WO2019144071A1 - Medical device delivery system with feedback loop - Google Patents
Medical device delivery system with feedback loop Download PDFInfo
- Publication number
- WO2019144071A1 WO2019144071A1 PCT/US2019/014408 US2019014408W WO2019144071A1 WO 2019144071 A1 WO2019144071 A1 WO 2019144071A1 US 2019014408 W US2019014408 W US 2019014408W WO 2019144071 A1 WO2019144071 A1 WO 2019144071A1
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- WO
- WIPO (PCT)
- Prior art keywords
- controller
- medical device
- drive motor
- shaft
- implantable medical
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3468—Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
- A61B2017/00336—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means with a protective sleeve, e.g. retractable or slidable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
- A61B2017/00411—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like actuated by application of energy from an energy source outside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
- A61B2090/066—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension for measuring torque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/9517—Instruments specially adapted for placement or removal of stents or stent-grafts handle assemblies therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0001—Means for transferring electromagnetic energy to implants
- A61F2250/0002—Means for transferring electromagnetic energy to implants for data transfer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0004—Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system
Definitions
- the present disclosure pertains to medical devices, and methods for manufacturing medical devices. More particularly, the present disclosure pertains to medical delivery devices for delivering implantable devices and that include a feedback loop pertaining to relative position of the implantable device relative to the delivery device.
- intracorporeal medical devices have been developed for medical use, for example, intravascular use. Some of these devices include guidewires, catheters, and the like. These devices are manufactured by any one of a variety of different manufacturing methods and may be used according to any one of a variety of methods. Of the known medical devices and methods, each has certain advantages and disadvantages. There is an ongoing need to provide alternative medical devices as well as alternative methods for manufacturing and using medical devices.
- An example of the disclosure is a system for implanting an implantable medical system.
- the system includes a delivery catheter including an outer shaft and an inner shaft translatable relative to the outer shaft, with the implantable medical device operably coupled to the inner shaft.
- a drive motor is operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft.
- the system includes a control mechanism that is configured to control operation of the drive motor and that includes a controller and a position sensor that is disposed relative to the delivery catheter.
- the position sensor is operably coupled to the controller such that the position sensor is able to provide the controller with an indication of the position of the implantable medical device relative to the outer shaft.
- the drive motor is configured to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor.
- the controller is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
- the drive motor may include a stepper motor, and the stepper motor may be configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
- the drive system may further include a motor position sensor, and the motor position sensor may be configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
- the drive motor may provide the controller with an indication of a power draw when operating the drive motor in order to cause the inner shaft to translate relative to the outer shaft.
- the controller may be configured to determine an amount of torque being applied to the inner shaft, via the indicated power draw, and the controller may be configured to analyze the applied torque to ascertain whether the inner shaft is moving freely or is jammed.
- the controller may be configured to analyze the applied torque to ascertain whether the implantable medical device is contacting tissue.
- the system may further include a strain gauge that is operably coupled to the inner shaft and/or the outer shaft, and is configured to output to the controller a signal indicating relative strain.
- the system may further include a user interface operably coupled to the controller such that the controller can output signals to the user via the user interface.
- the controller may be configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
- the controller may be configured to recognize compression and/or elongation of the inner shaft by comparing a position of the implantable medical device indicated by the position sensor and an expected position of the implantable medical device indicated by the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
- the implantable medical device may include an implantable heart valve.
- FIG. 1 Another example of the disclosure is a drive assembly for use with a delivery catheter for delivering an implantable medical device, where the delivery catheter includes an inner shaft slidingly disposed within an outer shaft, with the implantable medical device releasably coupled to the inner shaft.
- the drive assembly includes a drive motor that is configured to be operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft.
- a controller is configured to receive a position signal from a position sensor disposed relative to the delivery catheter, the position signal indicating a position of the implantable medical device relative to the outer shaft.
- the controller is configured to receive a motor signal indicating a rotational position or an accumulated rotational movement of an output shaft of the drive motor and is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
- the controller may be configured to receive from the drive motor an indication of a power draw when the drive motor engages the inner shaft, and the controller is configured to determine an amount of torque being applied to the inner shaft, via the indicated power draw, and the controller may be further configured to analyze the applied torque to ascertain whether the inner shaft is moving freely or is jammed.
- the controller may be configured to analyze the applied torque to ascertain whether the implantable medical device is contacting tissue.
- the controller may be configured to receive a signal indicating relative strain from a strain gauge that is operably coupled to the inner shaft and/or the outer shaft of the delivery catheter.
- the drive assembly may further include a user interface that is operably coupled to the controller such that the controller can output signals to the user via the user interface.
- the controller may be configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position of the drive motor.
- the delivery device includes an outer shaft and an inner shaft that is moveably disposed within the outer shaft, with the implantable medical device releasably secured to the inner shaft.
- a drive mechanism is operably coupled with the inner shaft and includes a drive motor rotatably coupled to the inner shaft, a controller and a position sensor that is operably coupled to the controller.
- the position sensor is able to provide the controller with an indication of the position of the implantable medical device relative to the outer shaft.
- a motor position sensor is operably coupled to the controller such that the motor position sensor is able to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor.
- the controller is configured to control operation of the drive motor in accordance with the information received from the position sensor and the motor position sensor.
- the delivery device may further include a user interface that is operably coupled to the controller.
- the controller may be configured to implement a hard stop, requiring user intervention for further movement, when the information received form the position sensor and the motor position sensor agree that the implantable medical device is ready to be deployed.
- FIG. 1 is a side view of an example medical device system
- FIG. 2 is a partial cross-sectional view of a portion of an example shaft
- FIG. 3 is a side view of an example medical device system
- FIG. 4 is a side view of an example medical device system
- FIG. 5 is a side view of an example medical device system
- FIG. 6 is a side view of an example medical device system
- FIG. 7 is a side view of an example medical device system
- FIG. 8 is a schematic block diagram of an example control system.
- references in the specification to “an embodiment”, “some embodiments”,“other embodiments”, etc. indicate that the embodiment described may include one or more particular features, structures, and/or characteristics. However, such recitations do not necessarily mean that all embodiments include the particular features, structures, and/or characteristics. Additionally, when particular features, structures, and/or characteristics are described in connection with one embodiment, it should be understood that such features, structures, and/or characteristics may also be used connection with other embodiments whether or not explicitly described unless clearly stated to the contrary.
- Some relatively common medical conditions may include or be the result of inefficiency, ineffectiveness, or complete failure of one or more of the valves within the heart.
- failure of the aortic valve or the mitral valve can have a serious effect on a human and could lead to serious health condition and/or death if not dealt with properly.
- Treatment of defective heart valves poses other challenges in that the treatment often requires the repair or outright replacement of the defective valve.
- Such therapies may be highly invasive to the patient.
- medical devices that may be used for delivering a medical device to a portion of the cardiovascular system in order to diagnose, treat, and/or repair the system.
- At least some of the medical devices disclosed herein may be used to deliver and implant a replacement heart valve (e.g., a replacement aortic valve, replacement mitral valve, etc.).
- a replacement heart valve e.g., a replacement aortic valve, replacement mitral valve, etc.
- the devices disclosed herein may deliver the replacement heart valve percutaneously and, thus, may be much less invasive to the patient.
- the devices disclosed herein may also provide a number of additional desirable features and benefits as described in more detail below.
- FIG. 1 The figures illustrate selected components and/or arrangements of a medical device system 10, shown schematically in FIG. 1 for example. It should be noted that in any given figure, some features of the medical device system 10 may not be shown, or may be shown schematically, for simplicity. Additional details regarding some of the components of the medical device system 10 may be illustrated in other figures in greater detail.
- a medical device system 10 may be used to deliver and/or deploy a variety of medical devices to a number of locations within the anatomy.
- the medical device system 10 may include a replacement heart valve delivery system (e.g., a replacement aortic valve delivery system) that can be used for percutaneous delivery of a medical implant 16, such as a replacement/prosthetic heart valve.
- a replacement heart valve delivery system e.g., a replacement aortic valve delivery system
- the medical device system 10 may also be used for other interventions including valve repair, valvuloplasty, delivery of an implantable medical device (e.g., such as a stent, graft, etc.), and the like, or other similar interventions.
- an implantable medical device e.g., such as a stent, graft, etc.
- the medical device system 10 may generally be described as a catheter system that includes an outer sheath 12, an inner catheter 14 (a portion of which is shown in FIG. 1 in phantom line) extending at least partially through a lumen of the outer sheath 12, and a medical implant 16 (e.g. , a replacement heart valve implant) which may be coupled to the inner catheter 14 and disposed within a lumen of the outer sheath 12 during delivery of the medical implant 16.
- a medical device handle 18 may be disposed at a proximal end of the outer sheath 12 and/or the inner catheter 14 and may include one or more actuation mechanisms associated therewith.
- a tubular member e.g., the outer sheath 12, the inner catheter 14, etc.
- the medical device handle 18 may be designed to manipulate the position of the outer sheath 12 relative to the inner catheter 14 and/or aid in the deployment of the medical implant 16.
- the medical device system 10 may be advanced percutaneously through the vasculature to a position adjacent to an area of interest and/or a treatment location.
- the medical device system 10 may be advanced through the vasculature to a position adjacent to a defective native valve (e.g., aortic valve, mitral valve, etc.) ⁇
- Alternative approaches to treat a defective aortic valve and/or other heart valve(s) are also contemplated with the medical device system 10.
- the medical implant 16 may be generally disposed in an elongated and low profile“delivery” configuration within the lumen and/or a distal end of the outer sheath 12, as seen schematically in FIG. 1 for example.
- the outer sheath 12 may be retracted relative to the medical implant 16 and/or the inner catheter 14 to expose the medical implant 16.
- the medical implant 16 may be self-expanding such that exposure of the medical implant 16 may deploy the medical implant 16.
- the medical implant 16 may be expanded/deployed using the medical device handle 18 in order to translate the medical implant 16 into a generally shortened and larger profile “deployed” configuration suitable for implantation within the anatomy.
- the inner catheter (or components thereof) may be coupled to medical implant 16 whereby actuation of the inner catheter 14 relative to the outer sheath 12 and/ or the medical implant 16 may deploy the medical device 16 within the anatomy.
- the medical device system 10 may be disconnected, detached, and/or released from the medical implant 16 and the medical device system 10 can be removed from the vasculature, leaving the medical implant 16 in place in a“released” configuration.
- an implantable medical device e.g., the medical implant 16
- portions of the medical device system 10 may be required to be advanced through tortuous and/or narrow body lumens. Therefore, it may be desirable to utilize components and design medical delivery systems (e.g., such as the medical device system 10 and/or other medical devices) that reduce the profile of portions of the medical device while maintaining sufficient strength (compressive, torsional, etc.) and flexibility of the system as a whole.
- FIG. 2 illustrates a portion of an example shaft 20 that may have increased resistance to compressive forces (e.g., a“compression-resistant” shaft) and/or may have increased resistance to tension forces (e.g., a“tension-resistant” shaft).
- the shaft 20 may be used as the inner catheter 14 in the medical device system 10 illustrated in FIG. 1.
- the shaft 20 may be other components of the medical device system 10, a component of a different medical device system (e.g., a stent delivery system, an angioplasty system, a biopsy system, etc.), any other medical device where compression and/or tension resistance may be desired, or the like.
- the shaft 20 may include an inner member or liner 22.
- the inner liner 22 may include a number of features as discussed herein.
- An outer member or exoskeleton 24 may be disposed along the inner liner 22.
- the exoskeleton 24 may include a plurality of discrete members or articulating links.
- the exoskeleton 24 may include a plurality of bead members 26 and a plurality of barrel members 28.
- Other discrete members are contemplated that may have differing shapes and/or configurations.
- the discrete members e.g., the bead members 26 and the barrel members 28
- the discrete members are engaged with one another and are designed to increase the compression resistance, the tension resistance, or both of the shaft 20 while also affording a desirable amount of flexibility and kink resistance such that the shaft 20 can be navigated through the anatomy.
- the inner liner 22 may include a number of features.
- the inner liners 22 may include one or more tension resistance members 30a/30b.
- the tension resistance members 30a/30b may take the form of a wire (e.g., a metallic wire), a braid, cable, stranded cable, a composite structure, or the like.
- the tension resistance members 30a/30b are both metallic wires.
- the tension resistance members 30a/30b are both metallic braids.
- the braids may further include an axial wire made from a suitable polymer or metal (e.g., aramid).
- the tension resistance members 30a/30b may be made from the same materials and/or have the same configuration.
- tension resistance members 30a/30b may be different from one another.
- FIG. 2 illustrates that the inner liner 22 includes two tension resistance members 30a/30b, this is not intended to be limiting.
- Other numbers of tension resistance members 30a/30b are contemplated such as one, three, four, five, six, seven, or more.
- the inner liner 22 may also include a lumen 32.
- a first tubular member 34 may be disposed within the lumen 32.
- the first tubular member may define a guidewire lumen 35, through which a guidewire 36 may extend.
- a second tubular member 38 may also be disposed within the lumen 32.
- the second tubular member 38 may define a lumen 39 through which an actuation mechanism 40 may extend.
- the inner liner 22 may vary in form.
- the inner liner 22 may include a single lumen, multiple lumens, or lack a lumen. Additional details regarding the exoskeleton 24 may be found, for example, in U.S. Provisional Patent Application Serial No. 62/425,419 and entitled “MEDICAL DEVICE SHAFT RESISTANT TO COMPRESSION AND/OR TENSION”, filed on November 22, 2016, which application is incorporated by reference herein in its entirety.
- FIG. 3 is a side view of an example medical device system 50 that may be considered as being an example of the medical device system 10 illustrated in FIG. 1.
- the medical device system 50 includes an outer sheath 52 that may be considered as an example of the outer sheath 12 as well as an inner catheter 54 that may be considered as an example of the inner catheter 14.
- the inner catheter 54 may include one or more lumens extending through the inner catheter 54, similar to the lumen 32 extending through the inner liner 22.
- a guidewire may extend through this lumen.
- an actuation mechanism 56 may extend through the inner catheter 54.
- the actuation mechanism 56 may, for example, include a force translation rod 58 that extends from a proximal end of the inner catheter 54 to a coupler 60.
- the actuation mechanism 56 may include several push pull rods 62 that extend distally from the coupler 60. In some cases, the actuation mechanism 56 may include three push pull rods 62, but in other cases there may be more than three push pull rods 62.
- FIG. 4 shows an example medical device system 70 in which a proximal end 72 of the force translation rod 58 is actuated by a drive motor 74 having an output shaft 76, where a gear assembly 80 engages the force translation rod 58 in such a way as to enable rotation of the output shaft 76 to cause the force translation rod 58 to translate distally and proximally. It will be appreciated that rotating the output shaft 76 in one direction will cause the force translation rod 58 to translate distally while rotating the output shaft 76 in the opposite direction will cause the force translation rod 58 to translate proximally.
- the medical device system 70 generally includes a position sensor 82.
- the position sensor 82 may take a variety of different forms, although as shown the position sensor 82 may include a coil 84 that is wrapped around the outer sheath 12 in order to detect proximity of an indicator 86 that is secured relative to the inner catheter 54.
- the indicator 86 may be secured relative to the coupler 60, as the coupler 60 indicates where the force translation rod 58 is coupled to the push pull rods 62.
- the position sensor 82 may be inductive.
- the coil 84 may detect the approach of a high permeability material.
- the position sensor 82 may include a switch that closes in proximity to the indicator 86.
- the position sensor 82 may be magnetic. Any of a variety of sensors may be used as the position sensor 82. Further examples of sensors that may be used as the position sensor 82 may be found in co-pending provisional applications filed on even-date herewith, with Attorney Docket 2001.1910100 entitled“CONDUCTANCE MODE DEPLOYMENT SENSORS FOR TRANSCATHETER VALVE SYSTEM” and Attorney Docket 2001.1911100 entitled“INDUCTANCE MODE DEPLOYMENT SENSORS FOR TRANSCATHETER VALVE SYSTEM”, both of which are incorporated by reference herein in their entirety.
- the medical device system 70 includes a position sensor measurement circuit 88 that is operably coupled to the position sensor 82 via a pair of electrical conductors 89.
- the position sensor measurement circuit 88 receives an electrical signal representative of where the indicator 86 is relative to the coil 84, and reports this to a motor control circuit 90. If the indicator 86 has not yet reached the coil 84, the motor control circuit 90 may determine that it is appropriate to drive the actuation mechanism 56 further in a distal direction. The motor control circuit 90 may provide a signal to the drive motor 74 to do so. It will be appreciated that this forms a closed loop control system in which position as indicated by the position sensor 82 impacts operation of the drive motor 74, which in turn impacts relative position.
- FIG. 5 shows an example medical device system 100 that is similar to the medical device system 70 shown in FIG. 4, but adds a feature.
- the drive motor 74 is able to provide feedback to the motor control circuit 90.
- the electrical current draw of the drive motor 74 is proportional to the force required to move the actuation mechanism 56. If for example the inner catheter 54 is binding within the outer sheath 52, the force required to move the actuation mechanism 56 will increase. As a result, the electrical current draw of the drive motor 74 will also increase. Accordingly, if the electrical current draw of the drive motor 74 increases, this indicates to the motor control circuit 90 that there may be a problem.
- an increase in torque as indicated by an increase in the electrical current draw to the drive motor 74 may be an indication that the medical implant 16 is contacting tissue, which may in turn be an indication that the medical implant 16 may be approaching or at an appropriate location for deployment. It will be appreciated that in some cases, a position signal from the position sensor 82 may be used in combination with a torque indication as provided by the electrical current draw of the drive motor 74 to determine whether the medical implant 16 is approaching or at an appropriate location for deployment, or if the actuation mechanism 56 is just binding in some manner, or if the medical implant 16 is moving normally.
- the medical device system 110 may also be able to look at torque versus position and be able to tell if the medical implant 16 is moving normally. For example, if the position indicates that the medical implant 16 is proximate an implantation site, but the indicated torque is lower than expected, this can be an indication that the medical implant 16 may be under-sized relative to the native valve annulus. Conversely, a higher than expected indicated torque could indicate that the medical implant 16 is too large, for example.
- FIG. 6 shows an example medical device system 110 that is similar to the medical device system 100 shown in FIG. 5, but adds a motor position sensor 92.
- the drive motor 74 may be a stepper motor that can output accurate position data, including rotational position and/or total number of rotations.
- the motor position sensor 92 may be configured to provide such data to the motor control circuit 90.
- the motor position sensor 92 may be a Hall effect sensor that can count revolutions of the drive motor 74, or even count fractions of a revolution, and can output this data to the motor control circuit 90.
- the motor control circuit 90 may control operation of the drive motor 74 in a closed loop fashion, relying on position data from both the position sensor 82 and the motor position sensor 92.
- FIG. 7 shows an example medical device system 120 that relies upon one or more strain gauges.
- the medical device system 120 includes an interior rod strain gauge 122 that is secured relative to the coupler 60 and an exterior strain gauge 124 that is secured relative to the outer sheath 52.
- one or both of the interior rod strain gauge 122 and the exterior strain gauge 124 may be inductive elements with a variable resonance characteristic that is modulated by compression and elongate forces.
- paired compressive/elongation measurements may be combined to discriminate between displacement and deployment forces that are applied to the medical implant 16.
- the medical device system 120 may utilize one or more of position data (although the position sensor 82 is not illustrated in FIG. 7), motor torque and deployment force data in a closed loop control system for controlling operation of the drive motor 74.
- FIG. 8 is a schematic block diagram of a control system 130 that may be used in controlling operation of the medical device systems 10, 50, 70, 100, 110, 120 discussed herein. In some cases, various features of the medical device systems 10, 50, 70, 100, 110, 120 may be combined as desired. In some cases, at least part of the control system 130 may be built into the handle 18 (FIG. 1). In some instances, at least part of the control system 130 may be distinct from the handle 18, and portions of the control system 130 distinct from the handle 18 may be electrically or optically coupled to portions of the control handle 130 that are built into the handle 18.
- the control system 130 includes a controller 132.
- the controller 132 may be considered as including at least some of the functionality discussed with respect to the position sensor measurement circuit 88 and the motor control circuit 90. In some instances, the controller 132 may for example be built into the handle 18 while other components, such as one or more of the position sensor 82, the motor position sensor 92, the inner strain gauge 122 and the outer strain gauge 124 may be disposed remote from the handle, closer to a distal end of the device and are operably coupled with the controller 132.
- the controller 132 may be operably coupled to a torque sensor 136.
- the controller 132 may be configured to monitor the electrical current draw of the drive motor 74, and thus can recognize when torque applied by the drive motor 74 increases.
- the controller 132 may be configured to also look at positional data from the position sensor 82, in order to determine whether the device is merely binding, or if the medical implant 16 is at or near an appropriate deployment location.
- the controller 132 may be configured to control operation of the drive motor 74.
- the controller 132 may be programmed or otherwise configured to accept inputs from the aforementioned sensors and to provide appropriate motor drive commands 138 to the drive motor 74.
- the controller 132 may provide a closed loop control system that receives translational information from the position sensor 82 and/or receives torque information, whether from a torque sensor 136, or by analyzing the electrical current draw of the drive motor 74, and outputs motor control signals to the drive motor 74 accordingly. In some instances, the controller 132 may detect jam conditions and/or over-torque conditions using the feedback for both the position sensor 82 and relevant torque data. In some cases, the controller 132 may utilize motor count information, such as either directly from the drive motor 74 itself, if a stepper motor, or from a motor position sensor such as the motor position sensor 92.
- the controller 132 may be configured to detect compression and/or stretch of the actuation mechanism 56 by comparing movement of the drive motor 74 near a proximal end of the device to movement detected by the position sensor 82 near a distal end of the device.
- the controller 132 may be configured to receive or develop torque displacement signature records, and may be able to perform signal analysis on an early portion of the deployment process in order to identify the appropriate torque displacement characteristic curve. For example, the controller 132 may be configured to determine if tissue has been contacted by comparing a torque force characteristic for deploying the medical implant 16 in air with the torque force characteristic of deploying the medical implant 16 in an implant procedure. A difference in torque force data from a baseline value may be used by the controller 132 to detect tissue displacement.
- the materials that can be used for the various components of the medical devices and/or systems disclosed herein may include those commonly associated with medical devices.
- the following discussion makes reference to the shaft 20. However, this is not intended to limit the devices and methods described herein, as the discussion may be applied to other shafts and/or components of the medical devices and/or systems disclosed herein including the various bead members, barrel members, etc.
- the shaft 20 may be made from a metal, metal alloy, polymer (some examples of which are disclosed below), a metal-polymer composite, ceramics, combinations thereof, and the like, or other suitable material.
- suitable polymers may include polytetrafluoroethylene (PTFE), ethylene tetrafluoroethylene (ETFE), fluorinated ethylene propylene (FEP), polyoxymethylene (POM, for example, DELRIN® available from DuPont), polyether block ester, polyurethane (for example, Polyurethane 85A), polypropylene (PP), polyvinylchloride (PVC), poly ether-ester (for example, ARNITEL® available from DSM Engineering Plastics), ether or ester based copolymers (for example, butylene/poly(alkylene ether) phthalate and/or other polyester elastomers such as HYTREL® available from DuPont), polyamide (for example, DURETHAN® available from Bayer or CRIS), poly(for
- suitable metals and metal alloys include stainless steel, such as 304V, 304L, and 316LV stainless steel; mild steel; nickel-titanium alloy such as linear-elastic and/or super-elastic nitinol; other nickel alloys such as nickel-chromium-molybdenum alloys (e.g., UNS: N06625 such as INCONEL® 625, UNS: N06022 such as HASTELLOY® C-22®, UNS: N10276 such as HASTELLOY® C276®, other HASTELLOY® alloys, and the like), nickel-copper alloys (e.g., UNS: N04400 such as MONEL® 400, NICKELVAC® 400, NICORROS® 400, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nickel-molybdenum alloys
- portions or all of the shaft may also be doped with, made of, or otherwise include a radiopaque material.
- Radiopaque materials are understood to be materials capable of producing a relatively bright image on a fluoroscopy screen or another imaging technique during a medical procedure. This relatively bright image aids the user of the shaft in determining its location.
- Some examples of radiopaque materials can include, but are not limited to, gold, platinum, palladium, tantalum, tungsten alloy, polymer material loaded with a radiopaque filler, and the like. Additionally, other radiopaque marker bands and/or coils may also be incorporated into the design of the shaft 20 to achieve the same result.
- the shaft 20 may include a material that does not substantially distort the image and create substantial artifacts (e.g., gaps in the image). Certain ferromagnetic materials, for example, may not be suitable because they may create artifacts in an MRI image.
- the shaft 20 may also be made from a material that the MRI machine can image.
- Some materials that exhibit these characteristics include, for example, tungsten, cobalt-chromium-molybdenum alloys (e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nitinol, and the like, and others.
- cobalt-chromium-molybdenum alloys e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like
- nickel-cobalt-chromium-molybdenum alloys e.g., UNS: R30035 such as MP35-N® and the like
- nitinol and the like, and others.
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Abstract
A drive assembly for use with a delivery catheter for delivering an implantable medical device includes a drive motor configured to be operably coupled to an inner shaft of the delivery catheter such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft and a controller. The controller is configured to receive a position signal from a position sensor indicating a position of the implantable medical device relative to the outer shaft as well as a motor signal indicating a rotational position of an output shaft of the drive motor. The controller is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
Description
MEDICAL DEVICE DELIVERY SYSTEM WITH FEEDBACK LOOP
Cross-Reference To Related Applications
[0001] This application claims the benefit of priority under 35 U.S.C. §119 to U.S.
Provisional Application Serial No. 62/619,325, filed January 19, 2018, the entirety of which is incorporated herein by reference.
Technical Field
[0002] The present disclosure pertains to medical devices, and methods for manufacturing medical devices. More particularly, the present disclosure pertains to medical delivery devices for delivering implantable devices and that include a feedback loop pertaining to relative position of the implantable device relative to the delivery device.
Background
[0003] A wide variety of intracorporeal medical devices have been developed for medical use, for example, intravascular use. Some of these devices include guidewires, catheters, and the like. These devices are manufactured by any one of a variety of different manufacturing methods and may be used according to any one of a variety of methods. Of the known medical devices and methods, each has certain advantages and disadvantages. There is an ongoing need to provide alternative medical devices as well as alternative methods for manufacturing and using medical devices.
Brief Summary
[0004] This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example of the disclosure is a system for implanting an implantable medical system. The system includes a delivery catheter including an outer shaft and an inner shaft translatable relative to the outer shaft, with the implantable medical device operably coupled to the inner shaft. A drive motor is operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft. The system includes a control mechanism that is configured to control operation of the drive motor and that includes a controller and a position sensor that is disposed relative to the delivery catheter. The position sensor is operably coupled to the controller such that the position sensor is able to provide the controller with an indication of the position of the implantable medical
device relative to the outer shaft. The drive motor is configured to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor. The controller is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
[0005] Alternatively or additionally to any of the embodiments above, the drive motor may include a stepper motor, and the stepper motor may be configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
[0006] Alternatively or additionally to any of the embodiments above, the drive system may further include a motor position sensor, and the motor position sensor may be configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
[0007] Alternatively or additionally to any of the embodiments above, the drive motor may provide the controller with an indication of a power draw when operating the drive motor in order to cause the inner shaft to translate relative to the outer shaft.
[0008] Alternatively or additionally to any of the embodiments above, the controller may be configured to determine an amount of torque being applied to the inner shaft, via the indicated power draw, and the controller may be configured to analyze the applied torque to ascertain whether the inner shaft is moving freely or is jammed.
[0009] Alternatively or additionally to any of the embodiments above, the controller may be configured to analyze the applied torque to ascertain whether the implantable medical device is contacting tissue.
[0010] Alternatively or additionally to any of the embodiments above, the system may further include a strain gauge that is operably coupled to the inner shaft and/or the outer shaft, and is configured to output to the controller a signal indicating relative strain.
[0011] Alternatively or additionally to any of the embodiments above, the system may further include a user interface operably coupled to the controller such that the controller can output signals to the user via the user interface.
[0012] Alternatively or additionally to any of the embodiments above, the controller may be configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
[0013] Alternatively or additionally to any of the embodiments above, the controller may be configured to recognize compression and/or elongation of the inner shaft by comparing a position of the implantable medical device indicated by the position sensor and an expected position of the implantable medical device indicated by the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
[0014] Alternatively or additionally to any of the embodiments above, the implantable medical device may include an implantable heart valve.
[0015] Another example of the disclosure is a drive assembly for use with a delivery catheter for delivering an implantable medical device, where the delivery catheter includes an inner shaft slidingly disposed within an outer shaft, with the implantable medical device releasably coupled to the inner shaft. The drive assembly includes a drive motor that is configured to be operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft. A controller is configured to receive a position signal from a position sensor disposed relative to the delivery catheter, the position signal indicating a position of the implantable medical device relative to the outer shaft. The controller is configured to receive a motor signal indicating a rotational position or an accumulated rotational movement of an output shaft of the drive motor and is configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
[0016] Alternatively or additionally to any of the embodiments above, the controller may be configured to receive from the drive motor an indication of a power draw when the drive motor engages the inner shaft, and the controller is configured to determine an amount of torque being applied to the inner shaft, via the indicated power draw, and the controller may be further configured to analyze the applied torque to ascertain whether the inner shaft is moving freely or is jammed.
[0017] Alternatively or additionally to any of the embodiments above, the controller may be configured to analyze the applied torque to ascertain whether the implantable medical device is contacting tissue.
[0018] Alternatively or additionally to any of the embodiments above, the controller may be configured to receive a signal indicating relative strain from a strain gauge that is operably coupled to the inner shaft and/or the outer shaft of the delivery catheter.
[0019] Alternatively or additionally to any of the embodiments above, the drive assembly may further include a user interface that is operably coupled to the controller such that the controller can output signals to the user via the user interface.
[0020] Alternatively or additionally to any of the embodiments above, the controller may be configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position of the drive motor.
[0021] Another example of the disclosure is a delivery device for an implantable medical device. The delivery device includes an outer shaft and an inner shaft that is moveably disposed within the outer shaft, with the implantable medical device releasably secured to the inner shaft. A drive mechanism is operably coupled with the inner shaft and includes a drive motor rotatably coupled to the inner shaft, a controller and a position sensor that is operably coupled to the controller. The position sensor is able to provide the controller with an indication of the position of the implantable medical device relative to the outer shaft. A motor position sensor is operably coupled to the controller such that the motor position sensor is able to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor. The controller is configured to control operation of the drive motor in accordance with the information received from the position sensor and the motor position sensor.
[0022] Alternatively or additionally to any of the embodiments above, the delivery device may further include a user interface that is operably coupled to the controller.
[0023] Alternatively or additionally to any of the embodiments above, the controller may be configured to implement a hard stop, requiring user intervention for further movement, when the information received form the position sensor and the motor position sensor agree that the implantable medical device is ready to be deployed.
[0024] The above summary of some embodiments is not intended to describe each disclosed embodiment or every implementation of the present disclosure. The Figures, and Detailed Description, which follow, more particularly exemplify these embodiments.
Brief Description of the Drawings
[0025] The disclosure may be more completely understood in consideration of the following detailed description in connection with the accompanying drawings, in which:
[0026] FIG. 1 is a side view of an example medical device system;
[0027] FIG. 2 is a partial cross-sectional view of a portion of an example shaft;
[0028] FIG. 3 is a side view of an example medical device system;
[0029] FIG. 4 is a side view of an example medical device system;
[0030] FIG. 5 is a side view of an example medical device system;
[0031] FIG. 6 is a side view of an example medical device system;
[0032] FIG. 7 is a side view of an example medical device system; and
[0033] FIG. 8 is a schematic block diagram of an example control system.
[0034] While the disclosure is amenable to various modifications and alternative forms, specifics thereof have been shown by way of example in the drawings and will be described in detail. It should be understood, however, that the intention is not to limit the disclosure to the particular embodiments described. On the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the disclosure.
Detailed Description
[0035] For the following defined terms, these definitions shall be applied, unless a different definition is given in the claims or elsewhere in this specification.
[0036] All numeric values are herein assumed to be modified by the term“about”, whether or not explicitly indicated. The term“about” generally refers to a range of numbers that one of skill in the art would consider equivalent to the recited value (e.g., having the same function or result). In many instances, the terms“about” may include numbers that are rounded to the nearest significant figure.
[0037] The recitation of numerical ranges by endpoints includes all numbers within that range (e.g. 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, and 5).
[0038] As used in this specification and the appended claims, the singular forms“a”,“an”, and“the” include plural referents unless the content clearly dictates otherwise. As used in this specification and the appended claims, the term“or” is generally employed in its sense including“and/or” unless the content clearly dictates otherwise.
[0039] It is noted that references in the specification to “an embodiment”, “some embodiments”,“other embodiments”, etc., indicate that the embodiment described may include one or more particular features, structures, and/or characteristics. However, such recitations do not necessarily mean that all embodiments include the particular features, structures, and/or characteristics. Additionally, when particular features, structures, and/or characteristics are described in connection with one embodiment, it should be understood that such features, structures, and/or characteristics may also be used connection with other embodiments whether or not explicitly described unless clearly stated to the contrary.
[0040] The following detailed description should be read with reference to the drawings in which similar elements in different drawings are numbered the same. The drawings, which are not necessarily to scale, depict illustrative embodiments and are not intended to limit the scope of the invention.
[0041] Diseases and/or medical conditions that impact the cardiovascular system are prevalent throughout the world. Traditionally, treatment of the cardiovascular system was often conducted by directly accessing the impacted part of the system. For example, treatment of a blockage in one or more of the coronary arteries was traditionally treated using coronary artery bypass surgery. As can be readily appreciated, such therapies are rather invasive to the patient and require significant recovery times and/or treatments. More recently, less invasive therapies have been developed, for example, where a blocked coronary artery could be accessed and treated via a percutaneous catheter (e.g., angioplasty). Such therapies have gained wide acceptance among patients and clinicians.
[0042] Some relatively common medical conditions may include or be the result of inefficiency, ineffectiveness, or complete failure of one or more of the valves within the heart. For example, failure of the aortic valve or the mitral valve can have a serious effect on a human and could lead to serious health condition and/or death if not dealt with properly. Treatment of defective heart valves poses other challenges in that the treatment often requires the repair or outright replacement of the defective valve. Such therapies may be highly invasive to the patient. Disclosed herein are medical devices that may be used for delivering a medical device
to a portion of the cardiovascular system in order to diagnose, treat, and/or repair the system. At least some of the medical devices disclosed herein may be used to deliver and implant a replacement heart valve (e.g., a replacement aortic valve, replacement mitral valve, etc.). In addition, the devices disclosed herein may deliver the replacement heart valve percutaneously and, thus, may be much less invasive to the patient. The devices disclosed herein may also provide a number of additional desirable features and benefits as described in more detail below.
[0043] The figures illustrate selected components and/or arrangements of a medical device system 10, shown schematically in FIG. 1 for example. It should be noted that in any given figure, some features of the medical device system 10 may not be shown, or may be shown schematically, for simplicity. Additional details regarding some of the components of the medical device system 10 may be illustrated in other figures in greater detail. A medical device system 10 may be used to deliver and/or deploy a variety of medical devices to a number of locations within the anatomy. In at least some embodiments, the medical device system 10 may include a replacement heart valve delivery system (e.g., a replacement aortic valve delivery system) that can be used for percutaneous delivery of a medical implant 16, such as a replacement/prosthetic heart valve. This, however, is not intended to be limiting as the medical device system 10 may also be used for other interventions including valve repair, valvuloplasty, delivery of an implantable medical device (e.g., such as a stent, graft, etc.), and the like, or other similar interventions.
[0044] The medical device system 10 may generally be described as a catheter system that includes an outer sheath 12, an inner catheter 14 (a portion of which is shown in FIG. 1 in phantom line) extending at least partially through a lumen of the outer sheath 12, and a medical implant 16 (e.g. , a replacement heart valve implant) which may be coupled to the inner catheter 14 and disposed within a lumen of the outer sheath 12 during delivery of the medical implant 16. In some embodiments, a medical device handle 18 may be disposed at a proximal end of the outer sheath 12 and/or the inner catheter 14 and may include one or more actuation mechanisms associated therewith. In other words, a tubular member (e.g., the outer sheath 12, the inner catheter 14, etc.) may extend distally from the medical device handle 18. In general, the medical device handle 18 may be designed to manipulate the position of the outer sheath 12 relative to the inner catheter 14 and/or aid in the deployment of the medical implant 16.
[0045] In use, the medical device system 10 may be advanced percutaneously through the vasculature to a position adjacent to an area of interest and/or a treatment location. For
example, in some embodiments, the medical device system 10 may be advanced through the vasculature to a position adjacent to a defective native valve (e.g., aortic valve, mitral valve, etc.)· Alternative approaches to treat a defective aortic valve and/or other heart valve(s) are also contemplated with the medical device system 10. During delivery, the medical implant 16 may be generally disposed in an elongated and low profile“delivery” configuration within the lumen and/or a distal end of the outer sheath 12, as seen schematically in FIG. 1 for example. Once positioned, the outer sheath 12 may be retracted relative to the medical implant 16 and/or the inner catheter 14 to expose the medical implant 16. In some instances, the medical implant 16 may be self-expanding such that exposure of the medical implant 16 may deploy the medical implant 16. Alternatively, the medical implant 16 may be expanded/deployed using the medical device handle 18 in order to translate the medical implant 16 into a generally shortened and larger profile “deployed” configuration suitable for implantation within the anatomy. For example, in some instances the inner catheter (or components thereof) may be coupled to medical implant 16 whereby actuation of the inner catheter 14 relative to the outer sheath 12 and/ or the medical implant 16 may deploy the medical device 16 within the anatomy. When the medical implant 16 is suitably deployed within the anatomy, the medical device system 10 may be disconnected, detached, and/or released from the medical implant 16 and the medical device system 10 can be removed from the vasculature, leaving the medical implant 16 in place in a“released” configuration.
[0046] It can be appreciated that during delivery and/or deployment of an implantable medical device (e.g., the medical implant 16), portions of the medical device system 10 may be required to be advanced through tortuous and/or narrow body lumens. Therefore, it may be desirable to utilize components and design medical delivery systems (e.g., such as the medical device system 10 and/or other medical devices) that reduce the profile of portions of the medical device while maintaining sufficient strength (compressive, torsional, etc.) and flexibility of the system as a whole.
[0047] FIG. 2 illustrates a portion of an example shaft 20 that may have increased resistance to compressive forces (e.g., a“compression-resistant” shaft) and/or may have increased resistance to tension forces (e.g., a“tension-resistant” shaft). In some instances, the shaft 20 may be used as the inner catheter 14 in the medical device system 10 illustrated in FIG. 1. However, the shaft 20 may be other components of the medical device system 10, a component of a different medical device system (e.g., a stent delivery system, an angioplasty
system, a biopsy system, etc.), any other medical device where compression and/or tension resistance may be desired, or the like.
[0048] The shaft 20 may include an inner member or liner 22. The inner liner 22 may include a number of features as discussed herein. An outer member or exoskeleton 24 may be disposed along the inner liner 22. The exoskeleton 24 may include a plurality of discrete members or articulating links. For example, the exoskeleton 24 may include a plurality of bead members 26 and a plurality of barrel members 28. Other discrete members are contemplated that may have differing shapes and/or configurations. In general, the discrete members (e.g., the bead members 26 and the barrel members 28) are engaged with one another and are designed to increase the compression resistance, the tension resistance, or both of the shaft 20 while also affording a desirable amount of flexibility and kink resistance such that the shaft 20 can be navigated through the anatomy.
[0049] As indicated above, the inner liner 22 may include a number of features. For example, the inner liners 22 may include one or more tension resistance members 30a/30b. The tension resistance members 30a/30b may take the form of a wire (e.g., a metallic wire), a braid, cable, stranded cable, a composite structure, or the like. In one example, the tension resistance members 30a/30b are both metallic wires. In another instance, the tension resistance members 30a/30b are both metallic braids. The braids may further include an axial wire made from a suitable polymer or metal (e.g., aramid). The tension resistance members 30a/30b may be made from the same materials and/or have the same configuration. Alternatively, the tension resistance members 30a/30b may be different from one another. Furthermore, while FIG. 2 illustrates that the inner liner 22 includes two tension resistance members 30a/30b, this is not intended to be limiting. Other numbers of tension resistance members 30a/30b are contemplated such as one, three, four, five, six, seven, or more.
[0050] The inner liner 22 may also include a lumen 32. In some instances, a first tubular member 34 may be disposed within the lumen 32. The first tubular member may define a guidewire lumen 35, through which a guidewire 36 may extend. A second tubular member 38 may also be disposed within the lumen 32. The second tubular member 38 may define a lumen 39 through which an actuation mechanism 40 may extend. These are just examples. The inner liner 22 may vary in form. For example, the inner liner 22 may include a single lumen, multiple lumens, or lack a lumen. Additional details regarding the exoskeleton 24 may be found, for example, in U.S. Provisional Patent Application Serial No. 62/425,419 and entitled “MEDICAL DEVICE SHAFT RESISTANT TO COMPRESSION AND/OR TENSION”,
filed on November 22, 2016, which application is incorporated by reference herein in its entirety.
[0051] FIG. 3 is a side view of an example medical device system 50 that may be considered as being an example of the medical device system 10 illustrated in FIG. 1. The medical device system 50 includes an outer sheath 52 that may be considered as an example of the outer sheath 12 as well as an inner catheter 54 that may be considered as an example of the inner catheter 14. In some cases, the inner catheter 54 may include one or more lumens extending through the inner catheter 54, similar to the lumen 32 extending through the inner liner 22. In some cases, a guidewire may extend through this lumen. In some instances, as illustrated, an actuation mechanism 56 may extend through the inner catheter 54. The actuation mechanism 56 may, for example, include a force translation rod 58 that extends from a proximal end of the inner catheter 54 to a coupler 60. The actuation mechanism 56 may include several push pull rods 62 that extend distally from the coupler 60. In some cases, the actuation mechanism 56 may include three push pull rods 62, but in other cases there may be more than three push pull rods 62.
[0052] As will be appreciated, the implantable medical device 16, which is shown coupled to the push pull rods 62, can be translated relative to the outer sheath 52 by pushing or pulling on the actuation mechanism 56. In some cases, as seen for example in FIG. 4, the actuation mechanism 56 may be electronically controlled. FIG. 4 shows an example medical device system 70 in which a proximal end 72 of the force translation rod 58 is actuated by a drive motor 74 having an output shaft 76, where a gear assembly 80 engages the force translation rod 58 in such a way as to enable rotation of the output shaft 76 to cause the force translation rod 58 to translate distally and proximally. It will be appreciated that rotating the output shaft 76 in one direction will cause the force translation rod 58 to translate distally while rotating the output shaft 76 in the opposite direction will cause the force translation rod 58 to translate proximally.
[0053] Several control features are also shown in FIG. 4. The medical device system 70 generally includes a position sensor 82. The position sensor 82 may take a variety of different forms, although as shown the position sensor 82 may include a coil 84 that is wrapped around the outer sheath 12 in order to detect proximity of an indicator 86 that is secured relative to the inner catheter 54. In some cases, the indicator 86 may be secured relative to the coupler 60, as the coupler 60 indicates where the force translation rod 58 is coupled to the push pull rods 62. In some cases, the position sensor 82 may be inductive. For example, the coil 84 may detect
the approach of a high permeability material. In some cases, the position sensor 82 may include a switch that closes in proximity to the indicator 86. In some instances, the position sensor 82 may be magnetic. Any of a variety of sensors may be used as the position sensor 82. Further examples of sensors that may be used as the position sensor 82 may be found in co-pending provisional applications filed on even-date herewith, with Attorney Docket 2001.1910100 entitled“CONDUCTANCE MODE DEPLOYMENT SENSORS FOR TRANSCATHETER VALVE SYSTEM” and Attorney Docket 2001.1911100 entitled“INDUCTANCE MODE DEPLOYMENT SENSORS FOR TRANSCATHETER VALVE SYSTEM”, both of which are incorporated by reference herein in their entirety.
[0054] The medical device system 70 includes a position sensor measurement circuit 88 that is operably coupled to the position sensor 82 via a pair of electrical conductors 89. In some cases, the position sensor measurement circuit 88 receives an electrical signal representative of where the indicator 86 is relative to the coil 84, and reports this to a motor control circuit 90. If the indicator 86 has not yet reached the coil 84, the motor control circuit 90 may determine that it is appropriate to drive the actuation mechanism 56 further in a distal direction. The motor control circuit 90 may provide a signal to the drive motor 74 to do so. It will be appreciated that this forms a closed loop control system in which position as indicated by the position sensor 82 impacts operation of the drive motor 74, which in turn impacts relative position.
[0055] FIG. 5 shows an example medical device system 100 that is similar to the medical device system 70 shown in FIG. 4, but adds a feature. In the medical device system 100, the drive motor 74 is able to provide feedback to the motor control circuit 90. In some cases, the electrical current draw of the drive motor 74 is proportional to the force required to move the actuation mechanism 56. If for example the inner catheter 54 is binding within the outer sheath 52, the force required to move the actuation mechanism 56 will increase. As a result, the electrical current draw of the drive motor 74 will also increase. Accordingly, if the electrical current draw of the drive motor 74 increases, this indicates to the motor control circuit 90 that there may be a problem. In some cases, an increase in torque as indicated by an increase in the electrical current draw to the drive motor 74 may be an indication that the medical implant 16 is contacting tissue, which may in turn be an indication that the medical implant 16 may be approaching or at an appropriate location for deployment. It will be appreciated that in some cases, a position signal from the position sensor 82 may be used in combination with a torque indication as provided by the electrical current draw of the drive motor 74 to determine whether
the medical implant 16 is approaching or at an appropriate location for deployment, or if the actuation mechanism 56 is just binding in some manner, or if the medical implant 16 is moving normally.
[0056] In some cases, the medical device system 110 may also be able to look at torque versus position and be able to tell if the medical implant 16 is moving normally. For example, if the position indicates that the medical implant 16 is proximate an implantation site, but the indicated torque is lower than expected, this can be an indication that the medical implant 16 may be under-sized relative to the native valve annulus. Conversely, a higher than expected indicated torque could indicate that the medical implant 16 is too large, for example.
[0057] FIG. 6 shows an example medical device system 110 that is similar to the medical device system 100 shown in FIG. 5, but adds a motor position sensor 92. In some cases, the drive motor 74 may be a stepper motor that can output accurate position data, including rotational position and/or total number of rotations. In some instances, however, the motor position sensor 92 may be configured to provide such data to the motor control circuit 90. For example, the motor position sensor 92 may be a Hall effect sensor that can count revolutions of the drive motor 74, or even count fractions of a revolution, and can output this data to the motor control circuit 90. In response, the motor control circuit 90 may control operation of the drive motor 74 in a closed loop fashion, relying on position data from both the position sensor 82 and the motor position sensor 92.
[0058] FIG. 7 shows an example medical device system 120 that relies upon one or more strain gauges. As illustrated, the medical device system 120 includes an interior rod strain gauge 122 that is secured relative to the coupler 60 and an exterior strain gauge 124 that is secured relative to the outer sheath 52. In some cases, one or both of the interior rod strain gauge 122 and the exterior strain gauge 124 may be inductive elements with a variable resonance characteristic that is modulated by compression and elongate forces. In some cases, paired compressive/elongation measurements may be combined to discriminate between displacement and deployment forces that are applied to the medical implant 16. In some instances, the medical device system 120 may utilize one or more of position data (although the position sensor 82 is not illustrated in FIG. 7), motor torque and deployment force data in a closed loop control system for controlling operation of the drive motor 74.
[0059] FIG. 8 is a schematic block diagram of a control system 130 that may be used in controlling operation of the medical device systems 10, 50, 70, 100, 110, 120 discussed herein.
In some cases, various features of the medical device systems 10, 50, 70, 100, 110, 120 may be combined as desired. In some cases, at least part of the control system 130 may be built into the handle 18 (FIG. 1). In some instances, at least part of the control system 130 may be distinct from the handle 18, and portions of the control system 130 distinct from the handle 18 may be electrically or optically coupled to portions of the control handle 130 that are built into the handle 18. The control system 130 includes a controller 132. In some cases, the controller 132 may be considered as including at least some of the functionality discussed with respect to the position sensor measurement circuit 88 and the motor control circuit 90. In some instances, the controller 132 may for example be built into the handle 18 while other components, such as one or more of the position sensor 82, the motor position sensor 92, the inner strain gauge 122 and the outer strain gauge 124 may be disposed remote from the handle, closer to a distal end of the device and are operably coupled with the controller 132.
[0060] In some cases, the controller 132 may be operably coupled to a torque sensor 136. In some instances, the controller 132 may be configured to monitor the electrical current draw of the drive motor 74, and thus can recognize when torque applied by the drive motor 74 increases. In some cases, the controller 132 may be configured to also look at positional data from the position sensor 82, in order to determine whether the device is merely binding, or if the medical implant 16 is at or near an appropriate deployment location. In some cases, the controller 132 may be configured to control operation of the drive motor 74. The controller 132 may be programmed or otherwise configured to accept inputs from the aforementioned sensors and to provide appropriate motor drive commands 138 to the drive motor 74.
[0061] The controller 132 may provide a closed loop control system that receives translational information from the position sensor 82 and/or receives torque information, whether from a torque sensor 136, or by analyzing the electrical current draw of the drive motor 74, and outputs motor control signals to the drive motor 74 accordingly. In some instances, the controller 132 may detect jam conditions and/or over-torque conditions using the feedback for both the position sensor 82 and relevant torque data. In some cases, the controller 132 may utilize motor count information, such as either directly from the drive motor 74 itself, if a stepper motor, or from a motor position sensor such as the motor position sensor 92. In some instances, the controller 132 may be configured to detect compression and/or stretch of the actuation mechanism 56 by comparing movement of the drive motor 74 near a proximal end of the device to movement detected by the position sensor 82 near a distal end of the device.
[0062] In some cases, the controller 132 may be configured to receive or develop torque displacement signature records, and may be able to perform signal analysis on an early portion of the deployment process in order to identify the appropriate torque displacement characteristic curve. For example, the controller 132 may be configured to determine if tissue has been contacted by comparing a torque force characteristic for deploying the medical implant 16 in air with the torque force characteristic of deploying the medical implant 16 in an implant procedure. A difference in torque force data from a baseline value may be used by the controller 132 to detect tissue displacement.
[0063] The materials that can be used for the various components of the medical devices and/or systems disclosed herein (e.g., shaft 20 and/or other shafts disclosed herein) may include those commonly associated with medical devices. For simplicity purposes, the following discussion makes reference to the shaft 20. However, this is not intended to limit the devices and methods described herein, as the discussion may be applied to other shafts and/or components of the medical devices and/or systems disclosed herein including the various bead members, barrel members, etc.
[0064] The shaft 20 may be made from a metal, metal alloy, polymer (some examples of which are disclosed below), a metal-polymer composite, ceramics, combinations thereof, and the like, or other suitable material. Some examples of suitable polymers may include polytetrafluoroethylene (PTFE), ethylene tetrafluoroethylene (ETFE), fluorinated ethylene propylene (FEP), polyoxymethylene (POM, for example, DELRIN® available from DuPont), polyether block ester, polyurethane (for example, Polyurethane 85A), polypropylene (PP), polyvinylchloride (PVC), poly ether-ester (for example, ARNITEL® available from DSM Engineering Plastics), ether or ester based copolymers (for example, butylene/poly(alkylene ether) phthalate and/or other polyester elastomers such as HYTREL® available from DuPont), polyamide (for example, DURETHAN® available from Bayer or CRISTAMID® available from Elf Atochem), elastomeric polyamides, block polyamide/ethers, polyether block amide (PEBA, for example available under the trade name PEBAX®), ethylene vinyl acetate copolymers (EVA), silicones, polyethylene (PE), high density polyethylene (HDPE), polyester, Marlex high-density polyethylene, Marlex low-density polyethylene, linear low density polyethylene (for example REXELL®), ultra-high molecular weight (UHMW) polyethylene, polypropylene, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), polytrimethylene terephthalate, polyethylene naphthalate (PEN), polyetheretherketone (PEEK), polyimide (PI), polyetherimide (PEI), polyphenylene sulfide (PPS), polyphenylene
oxide (PPO), poly paraphenylene terephthalamide (for example, KEVLAR®), polysulfone, nylon, nylon-l2 (such as GRILAMID® available from EMS American Grilon), perfluoro(propyl vinyl ether) (PFA), ethylene vinyl alcohol, polyolefin, polystyrene, epoxy, polyvinylidene chloride (PVdC), poly (sty rene-/ -isobutylene-/ -styrene) (for example, SIBS and/or SIBS 50A), polycarbonates, ionomers, biocompatible polymers, other suitable materials, or mixtures, combinations, copolymers thereof, polymer/metal composites, and the like. In some embodiments the sheath can be blended with a liquid crystal polymer (LCP).
[0065] Some examples of suitable metals and metal alloys include stainless steel, such as 304V, 304L, and 316LV stainless steel; mild steel; nickel-titanium alloy such as linear-elastic and/or super-elastic nitinol; other nickel alloys such as nickel-chromium-molybdenum alloys (e.g., UNS: N06625 such as INCONEL® 625, UNS: N06022 such as HASTELLOY® C-22®, UNS: N10276 such as HASTELLOY® C276®, other HASTELLOY® alloys, and the like), nickel-copper alloys (e.g., UNS: N04400 such as MONEL® 400, NICKELVAC® 400, NICORROS® 400, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nickel-molybdenum alloys (e.g., UNS: N10665 such as HASTELLOY® ALLOY B2®), other nickel-chromium alloys, other nickel-molybdenum alloys, other nickel-cobalt alloys, other nickel-iron alloys, other nickel-copper alloys, other nickel-tungsten or tungsten alloys, and the like; cobalt-chromium alloys; cobalt-chromium- molybdenum alloys (e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like); platinum enriched stainless steel; titanium; combinations thereof; and the like; or any other suitable material.
[0066] In at least some embodiments, portions or all of the shaft may also be doped with, made of, or otherwise include a radiopaque material. Radiopaque materials are understood to be materials capable of producing a relatively bright image on a fluoroscopy screen or another imaging technique during a medical procedure. This relatively bright image aids the user of the shaft in determining its location. Some examples of radiopaque materials can include, but are not limited to, gold, platinum, palladium, tantalum, tungsten alloy, polymer material loaded with a radiopaque filler, and the like. Additionally, other radiopaque marker bands and/or coils may also be incorporated into the design of the shaft 20 to achieve the same result.
[0067] In some embodiments, a degree of Magnetic Resonance Imaging (MRI) compatibility is imparted into the shaft. For example, the shaft 20 may include a material that does not substantially distort the image and create substantial artifacts (e.g., gaps in the image). Certain ferromagnetic materials, for example, may not be suitable because they may create
artifacts in an MRI image. The shaft 20 may also be made from a material that the MRI machine can image. Some materials that exhibit these characteristics include, for example, tungsten, cobalt-chromium-molybdenum alloys (e.g., UNS: R30003 such as ELGILOY®, PHYNOX®, and the like), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035 such as MP35-N® and the like), nitinol, and the like, and others.
[0068] It should be understood that this disclosure is, in many respects, only illustrative. Changes may be made in details, particularly in matters of shape, size, and arrangement of steps without exceeding the scope of the disclosure. This may include, to the extent that it is appropriate, the use of any of the features of one example embodiment being used in other embodiments. The disclosure’s scope is, of course, defined in the language in which the appended claims are expressed.
Claims
1. A system for implanting an implantable medical device, the system comprising: a delivery catheter including an outer shaft and an inner shaft translatable relative to the outer shaft, the implantable medical device operably coupled to the inner shaft;
a drive motor operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft; and
a control mechanism configured to control operation of the drive motor, the control mechanism including:
a controller; and
a position sensor disposed relative to the delivery catheter and operably coupled to the controller such that the position sensor is able to provide the controller with an indication of the position of the implantable medical device relative to the outer shaft;
the drive motor configured to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor; and
the controller configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
2. The system of claim 1, wherein the drive motor comprises a stepper motor, and the stepper motor is configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
3. The system of claim 1, further comprising a motor position sensor, and the motor position sensor is configured to provide the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
4. The system of any one of claims 1 to 3, wherein the drive motor provides the controller with an indication of a power draw when operating the drive motor in order to cause the inner shaft to translate relative to the outer shaft and the controller is configured to determine an amount of torque being applied to the inner shaft, via the indicated power draw,
and the controller is further configured to analyze the applied torque to ascertain whether the inner shaft is moving freely or is jammed.
5. The system of claim 4, wherein the controller is configured to analyze the applied torque to ascertain whether the implantable medical device is contacting tissue.
6. The system of any one of claims 1 to 5, further comprising a strain gauge operably coupled to the inner shaft and/or the outer shaft, and configured to output to the controller a signal indicating relative strain.
7. The system of any one of claims 1 to 6, further comprising a user interface operably coupled to the controller such that the controller can output signals to the user via the user interface.
8. The system of any one of claims 1 to 7, wherein the controller is configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
9. The system of any one of claims 1 to 8, wherein the controller is configured to recognize compression and/or elongation of the inner shaft by comparing a position of the implantable medical device indicated by the position sensor and an expected position of the implantable medical device indicated by the rotational position or the accumulated rotational movement of the output shaft of the drive motor.
10. A drive assembly for use with a delivery catheter for delivering an implantable medical device, the delivery catheter including an inner shaft slidingly disposed within an outer shaft, the implantable medical device releasably coupled to the inner shaft, the drive assembly comprising:
a drive motor configured to be operably coupled to the inner shaft such that operation of the drive motor causes the inner shaft to translate relative to the outer shaft; and
a controller;
the controller configured to receive a position signal from a position sensor disposed relative to the delivery catheter, the position signal indicating a position of the implantable medical device relative to the outer shaft;
the controller configured to receive a motor signal indicating a rotational position or an accumulated rotational movement of an output shaft of the drive motor; and
the controller configured to output a control signal instructing operation of the drive motor based upon the indicated rotational position or the accumulated rotational movement of the output shaft of the drive motor and the indicated position of the implantable medical device relative to the outer shaft.
11. The drive assembly of claim 10, wherein the controller is configured to receive a signal indicating relative strain from a strain gauge that is operably coupled to the inner shaft and/or the outer shaft of the delivery catheter.
12. The drive assembly of any one of claims 10 or 11, wherein the controller is configured to determine when the implantable medical device has reached a deployment position, based upon the indication of the position of the implantable medical device relative to the outer shaft and/or the indication of the rotational position of the output shaft of the drive motor.
13. A delivery device for an implantable medical device, the delivery device comprising:
an outer shaft;
an inner shaft moveably disposed within the outer shaft, the implantable medical device releasably secured to the inner shaft;
a drive mechanism operably coupled with the inner shaft, the drive mechanism including:
a drive motor rotatably coupled to the inner shaft;
a controller;
a position sensor operably coupled to the controller such that the position sensor is able to provide the controller with an indication of the position of the implantable medical device relative to the outer shaft;
a motor position sensor operably coupled to the controller such that the motor position sensor is able to provide the controller with an indication of a rotational position or an accumulated rotational movement of an output shaft of the drive motor; and
the controller configured to control operation of the drive motor in accordance with the information received from the position sensor and the motor position sensor.
14. The delivery device of claim 13, further comprising a user interface operably coupled to the controller.
15. The delivery device of any one of claims 13 or 14, wherein the controller is configured to implement a hard stop, requiring user intervention for further movement, when the information received from the position sensor and the motor position sensor agree that the implantable medical device is ready to be deployed.
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JP2020539804A JP7047106B2 (en) | 2018-01-19 | 2019-01-21 | Medical device delivery system with feedback loop |
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Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8663220B2 (en) | 2009-07-15 | 2014-03-04 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instruments |
US11090104B2 (en) | 2009-10-09 | 2021-08-17 | Cilag Gmbh International | Surgical generator for ultrasonic and electrosurgical devices |
US20140005705A1 (en) | 2012-06-29 | 2014-01-02 | Ethicon Endo-Surgery, Inc. | Surgical instruments with articulating shafts |
US9393037B2 (en) | 2012-06-29 | 2016-07-19 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US9408622B2 (en) | 2012-06-29 | 2016-08-09 | Ethicon Endo-Surgery, Llc | Surgical instruments with articulating shafts |
US9737355B2 (en) | 2014-03-31 | 2017-08-22 | Ethicon Llc | Controlling impedance rise in electrosurgical medical devices |
US10687884B2 (en) | 2015-09-30 | 2020-06-23 | Ethicon Llc | Circuits for supplying isolated direct current (DC) voltage to surgical instruments |
US10595930B2 (en) | 2015-10-16 | 2020-03-24 | Ethicon Llc | Electrode wiping surgical device |
US10299821B2 (en) | 2016-01-15 | 2019-05-28 | Ethicon Llc | Modular battery powered handheld surgical instrument with motor control limit profile |
US11229471B2 (en) | 2016-01-15 | 2022-01-25 | Cilag Gmbh International | Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization |
US10456193B2 (en) | 2016-05-03 | 2019-10-29 | Ethicon Llc | Medical device with a bilateral jaw configuration for nerve stimulation |
US11266430B2 (en) | 2016-11-29 | 2022-03-08 | Cilag Gmbh International | End effector control and calibration |
US12023086B2 (en) | 2019-12-30 | 2024-07-02 | Cilag Gmbh International | Electrosurgical instrument for delivering blended energy modalities to tissue |
US11812957B2 (en) | 2019-12-30 | 2023-11-14 | Cilag Gmbh International | Surgical instrument comprising a signal interference resolution system |
US12064109B2 (en) | 2019-12-30 | 2024-08-20 | Cilag Gmbh International | Surgical instrument comprising a feedback control circuit |
US11696776B2 (en) | 2019-12-30 | 2023-07-11 | Cilag Gmbh International | Articulatable surgical instrument |
US11937863B2 (en) | 2019-12-30 | 2024-03-26 | Cilag Gmbh International | Deflectable electrode with variable compression bias along the length of the deflectable electrode |
US11744636B2 (en) | 2019-12-30 | 2023-09-05 | Cilag Gmbh International | Electrosurgical systems with integrated and external power sources |
US11707318B2 (en) | 2019-12-30 | 2023-07-25 | Cilag Gmbh International | Surgical instrument with jaw alignment features |
US11986201B2 (en) | 2019-12-30 | 2024-05-21 | Cilag Gmbh International | Method for operating a surgical instrument |
US20210196362A1 (en) | 2019-12-30 | 2021-07-01 | Ethicon Llc | Electrosurgical end effectors with thermally insulative and thermally conductive portions |
US11786294B2 (en) | 2019-12-30 | 2023-10-17 | Cilag Gmbh International | Control program for modular combination energy device |
US11937866B2 (en) | 2019-12-30 | 2024-03-26 | Cilag Gmbh International | Method for an electrosurgical procedure |
US11779387B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Clamp arm jaw to minimize tissue sticking and improve tissue control |
US11950797B2 (en) | 2019-12-30 | 2024-04-09 | Cilag Gmbh International | Deflectable electrode with higher distal bias relative to proximal bias |
US11779329B2 (en) | 2019-12-30 | 2023-10-10 | Cilag Gmbh International | Surgical instrument comprising a flex circuit including a sensor system |
US11786291B2 (en) | 2019-12-30 | 2023-10-17 | Cilag Gmbh International | Deflectable support of RF energy electrode with respect to opposing ultrasonic blade |
US11452525B2 (en) | 2019-12-30 | 2022-09-27 | Cilag Gmbh International | Surgical instrument comprising an adjustment system |
US11660089B2 (en) * | 2019-12-30 | 2023-05-30 | Cilag Gmbh International | Surgical instrument comprising a sensing system |
US12053224B2 (en) | 2019-12-30 | 2024-08-06 | Cilag Gmbh International | Variation in electrode parameters and deflectable electrode to modify energy density and tissue interaction |
US11944366B2 (en) | 2019-12-30 | 2024-04-02 | Cilag Gmbh International | Asymmetric segmented ultrasonic support pad for cooperative engagement with a movable RF electrode |
WO2024163313A1 (en) * | 2023-01-30 | 2024-08-08 | Edwards Lifesciences Corporation | Prosthetic medical device delivery apparatus |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050149159A1 (en) * | 2003-12-23 | 2005-07-07 | Xtent, Inc., A Delaware Corporation | Devices and methods for controlling and indicating the length of an interventional element |
WO2016100799A1 (en) * | 2014-12-18 | 2016-06-23 | Medtronic Inc. | Transcatheter prosthetic heart valve delivery system with clinician feedback |
Family Cites Families (773)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US15192A (en) | 1856-06-24 | Tubular | ||
US2682057A (en) | 1951-07-24 | 1954-06-29 | Harry A Lord | Heart valve |
US2701559A (en) | 1951-08-02 | 1955-02-08 | William A Cooper | Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera |
US2832078A (en) | 1956-10-17 | 1958-04-29 | Battelle Memorial Institute | Heart valve |
US3029819A (en) | 1959-07-30 | 1962-04-17 | J L Mcatee | Artery graft and method of producing artery grafts |
US3099016A (en) | 1960-08-11 | 1963-07-30 | Edwards Miles Lowell | Heart valve |
US3130418A (en) | 1960-11-25 | 1964-04-28 | Louis R Head | Artificial heart valve and method for making same |
US3113586A (en) | 1962-09-17 | 1963-12-10 | Physio Control Company Inc | Artificial heart valve |
US3221006A (en) | 1962-11-13 | 1965-11-30 | Eastman Kodak Co | 5-amino-3-substituted-1,2,4-thiadiazole azo compounds |
US3143742A (en) | 1963-03-19 | 1964-08-11 | Surgitool Inc | Prosthetic sutureless heart valve |
US3367364A (en) | 1964-10-19 | 1968-02-06 | Univ Minnesota | Prosthetic heart valve |
US3334629A (en) | 1964-11-09 | 1967-08-08 | Bertram D Cohn | Occlusive device for inferior vena cava |
US3365728A (en) | 1964-12-18 | 1968-01-30 | Edwards Lab Inc | Upholstered heart valve having a sealing ring adapted for dispensing medicaments |
GB1127325A (en) | 1965-08-23 | 1968-09-18 | Henry Berry | Improved instrument for inserting artificial heart valves |
US3587115A (en) | 1966-05-04 | 1971-06-28 | Donald P Shiley | Prosthetic sutureless heart valves and implant tools therefor |
US3445916A (en) | 1967-04-19 | 1969-05-27 | Rudolf R Schulte | Method for making an anatomical check valve |
US3548417A (en) | 1967-09-05 | 1970-12-22 | Ronnie G Kischer | Heart valve having a flexible wall which rotates between open and closed positions |
US3540431A (en) | 1968-04-04 | 1970-11-17 | Kazi Mobin Uddin | Collapsible filter for fluid flowing in closed passageway |
US3570014A (en) | 1968-09-16 | 1971-03-16 | Warren D Hancock | Stent for heart valve |
US3671979A (en) | 1969-09-23 | 1972-06-27 | Univ Utah | Catheter mounted artificial heart valve for implanting in close proximity to a defective natural heart valve |
US3628535A (en) | 1969-11-12 | 1971-12-21 | Nibot Corp | Surgical instrument for implanting a prosthetic heart valve or the like |
US3592184A (en) | 1969-12-16 | 1971-07-13 | David H Watkins | Heart assist method and catheter |
US3642004A (en) | 1970-01-05 | 1972-02-15 | Life Support Equipment Corp | Urethral valve |
US3657744A (en) | 1970-05-08 | 1972-04-25 | Univ Minnesota | Method for fixing prosthetic implants in a living body |
US3714671A (en) | 1970-11-30 | 1973-02-06 | Cutter Lab | Tissue-type heart valve with a graft support ring or stent |
US3725961A (en) | 1970-12-29 | 1973-04-10 | Baxter Laboratories Inc | Prosthetic heart valve having fabric suturing element |
US3755823A (en) | 1971-04-23 | 1973-09-04 | Hancock Laboratories Inc | Flexible stent for heart valve |
US3868956A (en) | 1972-06-05 | 1975-03-04 | Ralph J Alfidi | Vessel implantable appliance and method of implanting it |
US3839741A (en) | 1972-11-17 | 1974-10-08 | J Haller | Heart valve and retaining means therefor |
US3795246A (en) | 1973-01-26 | 1974-03-05 | Bard Inc C R | Venocclusion device |
US3874388A (en) | 1973-02-12 | 1975-04-01 | Ochsner Med Found Alton | Shunt defect closure system |
US4291420A (en) | 1973-11-09 | 1981-09-29 | Medac Gesellschaft Fur Klinische Spezialpraparate Mbh | Artificial heart valve |
US3983581A (en) | 1975-01-20 | 1976-10-05 | William W. Angell | Heart valve stent |
US3997923A (en) | 1975-04-28 | 1976-12-21 | St. Jude Medical, Inc. | Heart valve prosthesis and suturing assembly and method of implanting a heart valve prosthesis in a heart |
US4035849A (en) | 1975-11-17 | 1977-07-19 | William W. Angell | Heart valve stent and process for preparing a stented heart valve prosthesis |
CA1069652A (en) | 1976-01-09 | 1980-01-15 | Alain F. Carpentier | Supported bioprosthetic heart valve with compliant orifice ring |
US4084268A (en) | 1976-04-22 | 1978-04-18 | Shiley Laboratories, Incorporated | Prosthetic tissue heart valve |
US4056854A (en) | 1976-09-28 | 1977-11-08 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Aortic heart valve catheter |
US5876419A (en) | 1976-10-02 | 1999-03-02 | Navius Corporation | Stent and method for making a stent |
US4297749A (en) | 1977-04-25 | 1981-11-03 | Albany International Corp. | Heart valve prosthesis |
US4233690A (en) | 1978-05-19 | 1980-11-18 | Carbomedics, Inc. | Prosthetic device couplings |
US4265694A (en) | 1978-12-14 | 1981-05-05 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making unitized three leaflet heart valve |
US4222126A (en) | 1978-12-14 | 1980-09-16 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education & Welfare | Unitized three leaflet heart valve |
US4574803A (en) | 1979-01-19 | 1986-03-11 | Karl Storz | Tissue cutter |
GB2056023B (en) | 1979-08-06 | 1983-08-10 | Ross D N Bodnar E | Stent for a cardiac valve |
US4373216A (en) | 1980-10-27 | 1983-02-15 | Hemex, Inc. | Heart valves having edge-guided occluders |
US4326306A (en) | 1980-12-16 | 1982-04-27 | Lynell Medical Technology, Inc. | Intraocular lens and manipulating tool therefor |
US4339831A (en) | 1981-03-27 | 1982-07-20 | Medtronic, Inc. | Dynamic annulus heart valve and reconstruction ring |
US4470157A (en) | 1981-04-27 | 1984-09-11 | Love Jack W | Tricuspid prosthetic tissue heart valve |
US4323358A (en) | 1981-04-30 | 1982-04-06 | Vascor, Inc. | Method for inhibiting mineralization of natural tissue during implantation |
US4345340A (en) | 1981-05-07 | 1982-08-24 | Vascor, Inc. | Stent for mitral/tricuspid heart valve |
US4501030A (en) | 1981-08-17 | 1985-02-26 | American Hospital Supply Corporation | Method of leaflet attachment for prosthetic heart valves |
US4865600A (en) | 1981-08-25 | 1989-09-12 | Baxter International Inc. | Mitral valve holder |
US4425908A (en) | 1981-10-22 | 1984-01-17 | Beth Israel Hospital | Blood clot filter |
US4406022A (en) | 1981-11-16 | 1983-09-27 | Kathryn Roy | Prosthetic valve means for cardiovascular surgery |
US4423809A (en) | 1982-02-05 | 1984-01-03 | Staar Surgical Company, Inc. | Packaging system for intraocular lens structures |
FR2523810B1 (en) | 1982-03-23 | 1988-11-25 | Carpentier Alain | ORGANIC GRAFT FABRIC AND PROCESS FOR ITS PREPARATION |
SE445884B (en) | 1982-04-30 | 1986-07-28 | Medinvent Sa | DEVICE FOR IMPLANTATION OF A RODFORM PROTECTION |
US4484579A (en) | 1982-07-19 | 1984-11-27 | University Of Pittsburgh | Commissurotomy catheter apparatus and method |
IT1212547B (en) | 1982-08-09 | 1989-11-30 | Iorio Domenico | INSTRUMENT FOR SURGICAL USE INTENDED TO MAKE INTERVENTIONS FOR THE IMPLANTATION OF BIOPROTESIS IN HUMAN ORGANS EASIER AND SAFER |
DE3230858C2 (en) | 1982-08-19 | 1985-01-24 | Ahmadi, Ali, Dr. med., 7809 Denzlingen | Ring prosthesis |
US4885005A (en) | 1982-11-12 | 1989-12-05 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US5215541A (en) | 1982-11-12 | 1993-06-01 | Baxter International Inc. | Surfactant treatment of implantable biological tissue to inhibit calcification |
US4680031A (en) | 1982-11-29 | 1987-07-14 | Tascon Medical Technology Corporation | Heart valve prosthesis |
GB8300636D0 (en) | 1983-01-11 | 1983-02-09 | Black M M | Heart valve replacements |
US4535483A (en) | 1983-01-17 | 1985-08-20 | Hemex, Inc. | Suture rings for heart valves |
US4610688A (en) | 1983-04-04 | 1986-09-09 | Pfizer Hospital Products Group, Inc. | Triaxially-braided fabric prosthesis |
US4834755A (en) | 1983-04-04 | 1989-05-30 | Pfizer Hospital Products Group, Inc. | Triaxially-braided fabric prosthesis |
AR229309A1 (en) | 1983-04-20 | 1983-07-15 | Barone Hector Daniel | MOUNT FOR CARDIAC VALVES |
US4612011A (en) | 1983-07-22 | 1986-09-16 | Hans Kautzky | Central occluder semi-biological heart valve |
US4531943A (en) | 1983-08-08 | 1985-07-30 | Angiomedics Corporation | Catheter with soft deformable tip |
US4665906A (en) | 1983-10-14 | 1987-05-19 | Raychem Corporation | Medical devices incorporating sim alloy elements |
US4585705A (en) | 1983-11-09 | 1986-04-29 | Dow Corning Corporation | Hard organopolysiloxane release coating |
US4787899A (en) | 1983-12-09 | 1988-11-29 | Lazarus Harrison M | Intraluminal graft device, system and method |
US5693083A (en) | 1983-12-09 | 1997-12-02 | Endovascular Technologies, Inc. | Thoracic graft and delivery catheter |
US4627436A (en) | 1984-03-01 | 1986-12-09 | Innoventions Biomedical Inc. | Angioplasty catheter and method for use thereof |
US4617932A (en) | 1984-04-25 | 1986-10-21 | Elliot Kornberg | Device and method for performing an intraluminal abdominal aortic aneurysm repair |
US4592340A (en) | 1984-05-02 | 1986-06-03 | Boyles Paul W | Artificial catheter means |
US4883458A (en) | 1987-02-24 | 1989-11-28 | Surgical Systems & Instruments, Inc. | Atherectomy system and method of using the same |
US4979939A (en) | 1984-05-14 | 1990-12-25 | Surgical Systems & Instruments, Inc. | Atherectomy system with a guide wire |
US5007896A (en) | 1988-12-19 | 1991-04-16 | Surgical Systems & Instruments, Inc. | Rotary-catheter for atherectomy |
DE3426300A1 (en) | 1984-07-17 | 1986-01-30 | Doguhan Dr.med. 6000 Frankfurt Baykut | TWO-WAY VALVE AND ITS USE AS A HEART VALVE PROSTHESIS |
US4580568A (en) | 1984-10-01 | 1986-04-08 | Cook, Incorporated | Percutaneous endovascular stent and method for insertion thereof |
DE3442088A1 (en) | 1984-11-17 | 1986-05-28 | Beiersdorf Ag, 2000 Hamburg | HEART VALVE PROSTHESIS |
SU1271508A1 (en) | 1984-11-29 | 1986-11-23 | Горьковский государственный медицинский институт им.С.М.Кирова | Artificial heart valve |
US4759758A (en) | 1984-12-07 | 1988-07-26 | Shlomo Gabbay | Prosthetic heart valve |
US4662885A (en) | 1985-09-03 | 1987-05-05 | Becton, Dickinson And Company | Percutaneously deliverable intravascular filter prosthesis |
GB2181057B (en) | 1985-10-23 | 1989-09-27 | Blagoveshchensk G Med Inst | Prosthetic valve holder |
US4733665C2 (en) | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
DE3640745A1 (en) | 1985-11-30 | 1987-06-04 | Ernst Peter Prof Dr M Strecker | Catheter for producing or extending connections to or between body cavities |
US4710192A (en) | 1985-12-30 | 1987-12-01 | Liotta Domingo S | Diaphragm and method for occlusion of the descending thoracic aorta |
SU1371700A1 (en) | 1986-02-21 | 1988-02-07 | МВТУ им.Н.Э.Баумана | Prosthesis of heart valve |
CH672247A5 (en) | 1986-03-06 | 1989-11-15 | Mo Vysshee Tekhnicheskoe Uchil | |
US4878906A (en) | 1986-03-25 | 1989-11-07 | Servetus Partnership | Endoprosthesis for repairing a damaged vessel |
US4777951A (en) | 1986-09-19 | 1988-10-18 | Mansfield Scientific, Inc. | Procedure and catheter instrument for treating patients for aortic stenosis |
IL83966A (en) | 1986-09-26 | 1992-03-29 | Schering Ag | Amides of aminopolycarboxylic acids and pharmaceutical compositions containing them |
DE3750480T2 (en) | 1986-11-29 | 1995-03-02 | Terumo Corp | BALLOONED CATHETER. |
US4878495A (en) | 1987-05-15 | 1989-11-07 | Joseph Grayzel | Valvuloplasty device with satellite expansion means |
US4872874A (en) | 1987-05-29 | 1989-10-10 | Taheri Syde A | Method and apparatus for transarterial aortic graft insertion and implantation |
US4796629A (en) | 1987-06-03 | 1989-01-10 | Joseph Grayzel | Stiffened dilation balloon catheter device |
US4829990A (en) | 1987-06-25 | 1989-05-16 | Thueroff Joachim | Implantable hydraulic penile erector |
JPH088933B2 (en) | 1987-07-10 | 1996-01-31 | 日本ゼオン株式会社 | Catheter |
US4851001A (en) | 1987-09-17 | 1989-07-25 | Taheri Syde A | Prosthetic valve for a blood vein and an associated method of implantation of the valve |
US5159937A (en) | 1987-09-30 | 1992-11-03 | Advanced Cardiovascular Systems, Inc. | Steerable dilatation catheter |
US4755181A (en) | 1987-10-08 | 1988-07-05 | Matrix Medica, Inc. | Anti-suture looping device for prosthetic heart valves |
US4819751A (en) | 1987-10-16 | 1989-04-11 | Baxter Travenol Laboratories, Inc. | Valvuloplasty catheter and method |
US4873978A (en) | 1987-12-04 | 1989-10-17 | Robert Ginsburg | Device and method for emboli retrieval |
JPH01290639A (en) | 1988-05-17 | 1989-11-22 | Daikin Ind Ltd | Production of 1,1,1-trifluoro-2,2-dichloroethane |
US4909252A (en) | 1988-05-26 | 1990-03-20 | The Regents Of The Univ. Of California | Perfusion balloon catheter |
US5032128A (en) | 1988-07-07 | 1991-07-16 | Medtronic, Inc. | Heart valve prosthesis |
US4917102A (en) | 1988-09-14 | 1990-04-17 | Advanced Cardiovascular Systems, Inc. | Guidewire assembly with steerable adjustable tip |
US4950227A (en) | 1988-11-07 | 1990-08-21 | Boston Scientific Corporation | Stent delivery system |
DE8815082U1 (en) | 1988-11-29 | 1989-05-18 | Biotronik Meß- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin, 1000 Berlin | Heart valve prosthesis |
US4927426A (en) | 1989-01-03 | 1990-05-22 | Dretler Stephen P | Catheter device |
US4856516A (en) | 1989-01-09 | 1989-08-15 | Cordis Corporation | Endovascular stent apparatus and method |
US4966604A (en) | 1989-01-23 | 1990-10-30 | Interventional Technologies Inc. | Expandable atherectomy cutter with flexibly bowed blades |
US5425739A (en) | 1989-03-09 | 1995-06-20 | Avatar Design And Development, Inc. | Anastomosis stent and stent selection system |
US4994077A (en) | 1989-04-21 | 1991-02-19 | Dobben Richard L | Artificial heart valve for implantation in a blood vessel |
WO1990014804A1 (en) | 1989-05-31 | 1990-12-13 | Baxter International Inc. | Biological valvular prosthesis |
US5609626A (en) | 1989-05-31 | 1997-03-11 | Baxter International Inc. | Stent devices and support/restrictor assemblies for use in conjunction with prosthetic vascular grafts |
US5047041A (en) | 1989-08-22 | 1991-09-10 | Samuels Peter B | Surgical apparatus for the excision of vein valves in situ |
US4986830A (en) | 1989-09-22 | 1991-01-22 | Schneider (U.S.A.) Inc. | Valvuloplasty catheter with balloon which remains stable during inflation |
US5089015A (en) | 1989-11-28 | 1992-02-18 | Promedica International | Method for implanting unstented xenografts and allografts |
US5002559A (en) | 1989-11-30 | 1991-03-26 | Numed | PTCA catheter |
US5591185A (en) | 1989-12-14 | 1997-01-07 | Corneal Contouring Development L.L.C. | Method and apparatus for reprofiling or smoothing the anterior or stromal cornea by scraping |
US5141494A (en) | 1990-02-15 | 1992-08-25 | Danforth Biomedical, Inc. | Variable wire diameter angioplasty dilatation balloon catheter |
US5238004A (en) | 1990-04-10 | 1993-08-24 | Boston Scientific Corporation | High elongation linear elastic guidewire |
US5037434A (en) | 1990-04-11 | 1991-08-06 | Carbomedics, Inc. | Bioprosthetic heart valve with elastic commissures |
DK124690D0 (en) | 1990-05-18 | 1990-05-18 | Henning Rud Andersen | FAT PROTECTION FOR IMPLEMENTATION IN THE BODY FOR REPLACEMENT OF NATURAL FLEET AND CATS FOR USE IN IMPLEMENTING A SUCH FAT PROTECTION |
US5085635A (en) | 1990-05-18 | 1992-02-04 | Cragg Andrew H | Valved-tip angiographic catheter |
US5411552A (en) | 1990-05-18 | 1995-05-02 | Andersen; Henning R. | Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis |
US5064435A (en) | 1990-06-28 | 1991-11-12 | Schneider (Usa) Inc. | Self-expanding prosthesis having stable axial length |
US5122154A (en) | 1990-08-15 | 1992-06-16 | Rhodes Valentine J | Endovascular bypass graft |
US5197979A (en) | 1990-09-07 | 1993-03-30 | Baxter International Inc. | Stentless heart valve and holder |
ES1015196Y (en) | 1990-09-21 | 1992-01-01 | Rosello Barbara Mariano | SURGICAL INSTRUMENT. |
US5161547A (en) | 1990-11-28 | 1992-11-10 | Numed, Inc. | Method of forming an intravascular radially expandable stent |
US5217483A (en) | 1990-11-28 | 1993-06-08 | Numed, Inc. | Intravascular radially expandable stent |
US6165292A (en) | 1990-12-18 | 2000-12-26 | Advanced Cardiovascular Systems, Inc. | Superelastic guiding member |
US5152771A (en) | 1990-12-31 | 1992-10-06 | The Board Of Supervisors Of Louisiana State University | Valve cutter for arterial by-pass surgery |
US5282847A (en) | 1991-02-28 | 1994-02-01 | Medtronic, Inc. | Prosthetic vascular grafts with a pleated structure |
JPH06508769A (en) | 1991-03-01 | 1994-10-06 | アプライド メディカル リソーセス コーポレイション | Cholangiography catheter |
JPH05184611A (en) | 1991-03-19 | 1993-07-27 | Kenji Kusuhara | Valvular annulation retaining member and its attaching method |
US5295958A (en) | 1991-04-04 | 1994-03-22 | Shturman Cardiology Systems, Inc. | Method and apparatus for in vivo heart valve decalcification |
US5167628A (en) | 1991-05-02 | 1992-12-01 | Boyles Paul W | Aortic balloon catheter assembly for indirect infusion of the coronary arteries |
US5397351A (en) | 1991-05-13 | 1995-03-14 | Pavcnik; Dusan | Prosthetic valve for percutaneous insertion |
US5350398A (en) | 1991-05-13 | 1994-09-27 | Dusan Pavcnik | Self-expanding filter for percutaneous insertion |
IT1245750B (en) | 1991-05-24 | 1994-10-14 | Sorin Biomedica Emodialisi S R | CARDIAC VALVE PROSTHESIS, PARTICULARLY FOR REPLACING THE AORTIC VALVE |
US5209741A (en) | 1991-07-08 | 1993-05-11 | Endomedix Corporation | Surgical access device having variable post-insertion cross-sectional geometry |
US5370685A (en) | 1991-07-16 | 1994-12-06 | Stanford Surgical Technologies, Inc. | Endovascular aortic valve replacement |
US5769812A (en) | 1991-07-16 | 1998-06-23 | Heartport, Inc. | System for cardiac procedures |
US5571215A (en) | 1993-02-22 | 1996-11-05 | Heartport, Inc. | Devices and methods for intracardiac procedures |
US6866650B2 (en) | 1991-07-16 | 2005-03-15 | Heartport, Inc. | System for cardiac procedures |
CA2117088A1 (en) | 1991-09-05 | 1993-03-18 | David R. Holmes | Flexible tubular device for use in medical applications |
US5258042A (en) | 1991-12-16 | 1993-11-02 | Henry Ford Health System | Intravascular hydrogel implant |
US5756476A (en) | 1992-01-14 | 1998-05-26 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of cell proliferation using antisense oligonucleotides |
US5507767A (en) | 1992-01-15 | 1996-04-16 | Cook Incorporated | Spiral stent |
EP0552579B1 (en) | 1992-01-22 | 1996-01-03 | Guy-Henri Muller | Prosthetic implants for plastic surgery |
US5489297A (en) | 1992-01-27 | 1996-02-06 | Duran; Carlos M. G. | Bioprosthetic heart valve with absorbable stent |
US5163953A (en) | 1992-02-10 | 1992-11-17 | Vince Dennis J | Toroidal artificial heart valve stent |
US5258023A (en) | 1992-02-12 | 1993-11-02 | Reger Medical Development, Inc. | Prosthetic heart valve |
US5683448A (en) | 1992-02-21 | 1997-11-04 | Boston Scientific Technology, Inc. | Intraluminal stent and graft |
DE69333161T2 (en) | 1992-05-08 | 2004-06-03 | Schneider (Usa) Inc., Plymouth | Stent for the esophagus |
US5332402A (en) | 1992-05-12 | 1994-07-26 | Teitelbaum George P | Percutaneously-inserted cardiac valve |
FR2693366B1 (en) | 1992-07-09 | 1994-09-02 | Celsa Lg | Device forming a vascular prosthesis usable for the treatment of aneurysms. |
US5409019A (en) | 1992-10-30 | 1995-04-25 | Wilk; Peter J. | Coronary artery by-pass method |
JP2935751B2 (en) | 1993-01-14 | 1999-08-16 | ミードックス メディカルズ インコーポレイテッド | Radially expandable tubular prosthesis |
US5728151A (en) | 1993-02-22 | 1998-03-17 | Heartport, Inc. | Intercostal access devices for less-invasive cardiovascular surgery |
US5431676A (en) | 1993-03-05 | 1995-07-11 | Innerdyne Medical, Inc. | Trocar system having expandable port |
US5772609A (en) | 1993-05-11 | 1998-06-30 | Target Therapeutics, Inc. | Guidewire with variable flexibility due to polymeric coatings |
US5480423A (en) | 1993-05-20 | 1996-01-02 | Boston Scientific Corporation | Prosthesis delivery |
GB9312666D0 (en) | 1993-06-18 | 1993-08-04 | Vesely Ivan | Bioprostetic heart valve |
US5415633A (en) | 1993-07-28 | 1995-05-16 | Active Control Experts, Inc. | Remotely steered catheterization device |
US5443495A (en) | 1993-09-17 | 1995-08-22 | Scimed Lifesystems Inc. | Polymerization angioplasty balloon implant device |
KR970004845Y1 (en) | 1993-09-27 | 1997-05-21 | 주식회사 수호메디테크 | Stent for expanding a lumen |
US5545209A (en) | 1993-09-30 | 1996-08-13 | Texas Petrodet, Inc. | Controlled deployment of a medical device |
JP3336434B2 (en) | 1993-09-30 | 2002-10-21 | エンドガド リサーチ ピー・ティー・ワイ リミテッド | Endoluminal graft |
US5389106A (en) | 1993-10-29 | 1995-02-14 | Numed, Inc. | Impermeable expandable intravascular stent |
US5480424A (en) | 1993-11-01 | 1996-01-02 | Cox; James L. | Heart valve replacement using flexible tubes |
US5713950A (en) | 1993-11-01 | 1998-02-03 | Cox; James L. | Method of replacing heart valves using flexible tubes |
ES2135520T3 (en) | 1993-11-04 | 1999-11-01 | Bard Inc C R | NON-MIGRANT VASCULAR PROSTHESIS. |
AU1091095A (en) | 1993-11-08 | 1995-05-29 | Harrison M. Lazarus | Intraluminal vascular graft and method |
CA2129284C (en) * | 1993-11-24 | 1999-03-09 | Kenneth J. Niehoff | Controlling plunger drives for fluid injection in animals |
RU2089131C1 (en) | 1993-12-28 | 1997-09-10 | Сергей Апполонович Пульнев | Stent-expander |
DE4401227C2 (en) | 1994-01-18 | 1999-03-18 | Ernst Peter Prof Dr M Strecker | Endoprosthesis implantable percutaneously in a patient's body |
US5476506A (en) | 1994-02-08 | 1995-12-19 | Ethicon, Inc. | Bi-directional crimped graft |
US5609627A (en) | 1994-02-09 | 1997-03-11 | Boston Scientific Technology, Inc. | Method for delivering a bifurcated endoluminal prosthesis |
US5443477A (en) | 1994-02-10 | 1995-08-22 | Stentco, Inc. | Apparatus and method for deployment of radially expandable stents by a mechanical linkage |
US5549663A (en) | 1994-03-09 | 1996-08-27 | Cordis Corporation | Endoprosthesis having graft member and exposed welded end junctions, method and procedure |
US5556413A (en) | 1994-03-11 | 1996-09-17 | Advanced Cardiovascular Systems, Inc. | Coiled stent with locking ends |
US5476510A (en) | 1994-04-21 | 1995-12-19 | Medtronic, Inc. | Holder for heart valve |
DE4415359C2 (en) | 1994-05-02 | 1997-10-23 | Aesculap Ag | Surgical tubular shaft instrument |
US6139510A (en) | 1994-05-11 | 2000-10-31 | Target Therapeutics Inc. | Super elastic alloy guidewire |
US5765418A (en) | 1994-05-16 | 1998-06-16 | Medtronic, Inc. | Method for making an implantable medical device from a refractory metal |
CA2149290C (en) | 1994-05-26 | 2006-07-18 | Carl T. Urban | Optical trocar |
US5824041A (en) | 1994-06-08 | 1998-10-20 | Medtronic, Inc. | Apparatus and methods for placement and repositioning of intraluminal prostheses |
US5728068A (en) | 1994-06-14 | 1998-03-17 | Cordis Corporation | Multi-purpose balloon catheter |
US5522881A (en) | 1994-06-28 | 1996-06-04 | Meadox Medicals, Inc. | Implantable tubular prosthesis having integral cuffs |
EP1695673A3 (en) | 1994-07-08 | 2009-07-08 | ev3 Inc. | Intravascular filtering device |
DE4424242A1 (en) | 1994-07-09 | 1996-01-11 | Ernst Peter Prof Dr M Strecker | Endoprosthesis implantable percutaneously in a patient's body |
US5554185A (en) | 1994-07-18 | 1996-09-10 | Block; Peter C. | Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same |
US5545133A (en) | 1994-09-16 | 1996-08-13 | Scimed Life Systems, Inc. | Balloon catheter with improved pressure source |
WO1996019611A1 (en) | 1994-12-21 | 1996-06-27 | Novo Nordisk A/S | A method for enzymatic treatment of wool |
US5674277A (en) | 1994-12-23 | 1997-10-07 | Willy Rusch Ag | Stent for placement in a body tube |
BE1009085A3 (en) | 1995-02-10 | 1996-11-05 | De Fays Robert Dr | Intra-aortic prosthesis and surgical instruments for the introduction, implementation and fixing in the aortic prosthesis. |
US5575818A (en) | 1995-02-14 | 1996-11-19 | Corvita Corporation | Endovascular stent with locking ring |
WO1996025897A2 (en) | 1995-02-22 | 1996-08-29 | Menlo Care, Inc. | Covered expanding mesh stent |
US5681345A (en) | 1995-03-01 | 1997-10-28 | Scimed Life Systems, Inc. | Sleeve carrying stent |
EP0819014B1 (en) | 1995-03-30 | 2003-02-05 | Heartport, Inc. | Endovascular cardiac venting catheter |
ATE269742T1 (en) | 1995-03-30 | 2004-07-15 | Heartport Inc | SYSTEM FOR PERFORMING ENDOVASCULAR PROCEDURES |
US5709713A (en) | 1995-03-31 | 1998-01-20 | Cardiovascular Concepts, Inc. | Radially expansible vascular prosthesis having reversible and other locking structures |
US5667523A (en) | 1995-04-28 | 1997-09-16 | Impra, Inc. | Dual supported intraluminal graft |
US5824064A (en) | 1995-05-05 | 1998-10-20 | Taheri; Syde A. | Technique for aortic valve replacement with simultaneous aortic arch graft insertion and apparatus therefor |
US5534007A (en) | 1995-05-18 | 1996-07-09 | Scimed Life Systems, Inc. | Stent deployment catheter with collapsible sheath |
US5571175A (en) | 1995-06-07 | 1996-11-05 | St. Jude Medical, Inc. | Suture guard for prosthetic heart valve |
WO1996040011A1 (en) | 1995-06-07 | 1996-12-19 | St. Jude Medical, Inc. | Direct suture orifice for mechanical heart valve |
US5716417A (en) | 1995-06-07 | 1998-02-10 | St. Jude Medical, Inc. | Integral supporting structure for bioprosthetic heart valve |
US5728152A (en) | 1995-06-07 | 1998-03-17 | St. Jude Medical, Inc. | Bioresorbable heart valve support |
DE19532846A1 (en) | 1995-09-06 | 1997-03-13 | Georg Dr Berg | Valve for use in heart |
US5769882A (en) | 1995-09-08 | 1998-06-23 | Medtronic, Inc. | Methods and apparatus for conformably sealing prostheses within body lumens |
US5735842A (en) | 1995-09-11 | 1998-04-07 | St. Jude Medical, Inc. | Low profile manipulators for heart valve prostheses |
US5807405A (en) | 1995-09-11 | 1998-09-15 | St. Jude Medical, Inc. | Apparatus for attachment of heart valve holder to heart valve prosthesis |
US6193745B1 (en) | 1995-10-03 | 2001-02-27 | Medtronic, Inc. | Modular intraluminal prosteheses construction and methods |
US5824037A (en) | 1995-10-03 | 1998-10-20 | Medtronic, Inc. | Modular intraluminal prostheses construction and methods |
US6287336B1 (en) | 1995-10-16 | 2001-09-11 | Medtronic, Inc. | Variable flexibility stent |
US5591195A (en) | 1995-10-30 | 1997-01-07 | Taheri; Syde | Apparatus and method for engrafting a blood vessel |
DE19546692C2 (en) | 1995-12-14 | 2002-11-07 | Hans-Reiner Figulla | Self-expanding heart valve prosthesis for implantation in the human body via a catheter system |
US5861028A (en) | 1996-09-09 | 1999-01-19 | Shelhigh Inc | Natural tissue heart valve and stent prosthesis and method for making the same |
US5855602A (en) | 1996-09-09 | 1999-01-05 | Shelhigh, Inc. | Heart valve prosthesis |
US5843158A (en) | 1996-01-05 | 1998-12-01 | Medtronic, Inc. | Limited expansion endoluminal prostheses and methods for their use |
ATE290832T1 (en) | 1996-01-05 | 2005-04-15 | Medtronic Inc | EXPANDABLE ENDOLUMINAL PROSTHESES |
EP1011889B1 (en) | 1996-01-30 | 2002-10-30 | Medtronic, Inc. | Articles for and methods of making stents |
JPH09215753A (en) | 1996-02-08 | 1997-08-19 | Schneider Usa Inc | Self-expanding stent made of titanium alloy |
US6402736B1 (en) | 1996-02-16 | 2002-06-11 | Joe E. Brown | Apparatus and method for filtering intravascular fluids and for delivering diagnostic and therapeutic agents |
US6402780B2 (en) | 1996-02-23 | 2002-06-11 | Cardiovascular Technologies, L.L.C. | Means and method of replacing a heart valve in a minimally invasive manner |
US5716370A (en) | 1996-02-23 | 1998-02-10 | Williamson, Iv; Warren | Means for replacing a heart valve in a minimally invasive manner |
US5695498A (en) | 1996-02-28 | 1997-12-09 | Numed, Inc. | Stent implantation system |
US5720391A (en) | 1996-03-29 | 1998-02-24 | St. Jude Medical, Inc. | Packaging and holder for heart valve prosthesis |
US5891191A (en) | 1996-04-30 | 1999-04-06 | Schneider (Usa) Inc | Cobalt-chromium-molybdenum alloy stent and stent-graft |
US5885228A (en) | 1996-05-08 | 1999-03-23 | Heartport, Inc. | Valve sizer and method of use |
AU3122197A (en) | 1996-05-14 | 1997-12-05 | Embol-X, Inc. | Aortic occluder with associated filter and methods of use during cardiac surgery |
DE69719237T2 (en) | 1996-05-23 | 2003-11-27 | Samsung Electronics Co., Ltd. | Flexible, self-expandable stent and method for its manufacture |
US7238197B2 (en) | 2000-05-30 | 2007-07-03 | Devax, Inc. | Endoprosthesis deployment system for treating vascular bifurcations |
BR9709867A (en) | 1996-06-20 | 2000-01-11 | Sulzer Vascutek Ltda | Device for retaining a prosthesis in a passage of the body device for fixing a prosthesis on an internal surface of a body passage, prosthetic device, prosthesis and process for fixing a prosthetic device, for repairing a vessel and for inserting a prosthesis in a passage of the body. |
US5855601A (en) | 1996-06-21 | 1999-01-05 | The Trustees Of Columbia University In The City Of New York | Artificial heart valve and method and device for implanting the same |
US5843161A (en) | 1996-06-26 | 1998-12-01 | Cordis Corporation | Endoprosthesis assembly for percutaneous deployment and method of deploying same |
US5662671A (en) | 1996-07-17 | 1997-09-02 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
US5755783A (en) | 1996-07-29 | 1998-05-26 | Stobie; Robert | Suture rings for rotatable artificial heart valves |
US6702851B1 (en) | 1996-09-06 | 2004-03-09 | Joseph A. Chinn | Prosthetic heart valve with surface modification |
US6764509B2 (en) | 1996-09-06 | 2004-07-20 | Carbomedics Inc. | Prosthetic heart valve with surface modification |
US5800531A (en) | 1996-09-30 | 1998-09-01 | Baxter International Inc. | Bioprosthetic heart valve implantation device |
DE69732349D1 (en) | 1996-10-01 | 2005-03-03 | Numed Inc | EXPANDABLE STENT |
US5749890A (en) | 1996-12-03 | 1998-05-12 | Shaknovich; Alexander | Method and system for stent placement in ostial lesions |
NL1004827C2 (en) | 1996-12-18 | 1998-06-19 | Surgical Innovations Vof | Device for regulating blood circulation. |
US6206911B1 (en) | 1996-12-19 | 2001-03-27 | Simcha Milo | Stent combination |
US6015431A (en) | 1996-12-23 | 2000-01-18 | Prograft Medical, Inc. | Endolumenal stent-graft with leak-resistant seal |
EP0850607A1 (en) | 1996-12-31 | 1998-07-01 | Cordis Corporation | Valve prosthesis for implantation in body channels |
GB9701479D0 (en) | 1997-01-24 | 1997-03-12 | Aortech Europ Ltd | Heart valve |
US6241757B1 (en) | 1997-02-04 | 2001-06-05 | Solco Surgical Instrument Co., Ltd. | Stent for expanding body's lumen |
WO1998036790A1 (en) | 1997-02-19 | 1998-08-27 | Condado Medical Devices Corporation | Multi-purpose catheters, catheter systems, and radiation treatment |
US6152946A (en) | 1998-03-05 | 2000-11-28 | Scimed Life Systems, Inc. | Distal protection device and method |
US5830229A (en) | 1997-03-07 | 1998-11-03 | Micro Therapeutics Inc. | Hoop stent |
US6416510B1 (en) | 1997-03-13 | 2002-07-09 | Biocardia, Inc. | Drug delivery catheters that attach to tissue and methods for their use |
US5817126A (en) | 1997-03-17 | 1998-10-06 | Surface Genesis, Inc. | Compound stent |
US5824053A (en) | 1997-03-18 | 1998-10-20 | Endotex Interventional Systems, Inc. | Helical mesh endoprosthesis and methods of use |
US5824055A (en) | 1997-03-25 | 1998-10-20 | Endotex Interventional Systems, Inc. | Stent graft delivery system and methods of use |
US5928281A (en) | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
US5860966A (en) | 1997-04-16 | 1999-01-19 | Numed, Inc. | Method of securing a stent on a balloon catheter |
US5868783A (en) | 1997-04-16 | 1999-02-09 | Numed, Inc. | Intravascular stent with limited axial shrinkage |
JP4083241B2 (en) | 1997-04-23 | 2008-04-30 | アーテミス・メディカル・インコーポレイテッド | Bifurcated stent and distal protection system |
US5957949A (en) | 1997-05-01 | 1999-09-28 | World Medical Manufacturing Corp. | Percutaneous placement valve stent |
US6206917B1 (en) | 1997-05-02 | 2001-03-27 | St. Jude Medical, Inc. | Differential treatment of prosthetic devices |
US5855597A (en) | 1997-05-07 | 1999-01-05 | Iowa-India Investments Co. Limited | Stent valve and stent graft for percutaneous surgery |
US6245102B1 (en) | 1997-05-07 | 2001-06-12 | Iowa-India Investments Company Ltd. | Stent, stent graft and stent valve |
US6162245A (en) | 1997-05-07 | 2000-12-19 | Iowa-India Investments Company Limited | Stent valve and stent graft |
US6676682B1 (en) | 1997-05-08 | 2004-01-13 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US5911734A (en) | 1997-05-08 | 1999-06-15 | Embol-X, Inc. | Percutaneous catheter and guidewire having filter and medical device deployment capabilities |
US6258120B1 (en) | 1997-12-23 | 2001-07-10 | Embol-X, Inc. | Implantable cerebral protection device and methods of use |
US6007575A (en) | 1997-06-06 | 1999-12-28 | Samuels; Shaun Laurence Wilkie | Inflatable intraluminal stent and method for affixing same within the human body |
JP3645399B2 (en) | 1997-06-09 | 2005-05-11 | 住友金属工業株式会社 | Endovascular stent |
WO1998057599A2 (en) | 1997-06-17 | 1998-12-23 | Sante Camilli | Implantable valve for blood vessels |
US6635080B1 (en) | 1997-06-19 | 2003-10-21 | Vascutek Limited | Prosthesis for repair of body passages |
US5861024A (en) | 1997-06-20 | 1999-01-19 | Cardiac Assist Devices, Inc | Electrophysiology catheter and remote actuator therefor |
US5906619A (en) | 1997-07-24 | 1999-05-25 | Medtronic, Inc. | Disposable delivery device for endoluminal prostheses |
US6340367B1 (en) | 1997-08-01 | 2002-01-22 | Boston Scientific Scimed, Inc. | Radiopaque markers and methods of using the same |
US5984957A (en) | 1997-08-12 | 1999-11-16 | Schneider (Usa) Inc | Radially expanded prostheses with axial diameter control |
US6306164B1 (en) | 1997-09-05 | 2001-10-23 | C. R. Bard, Inc. | Short body endoprosthesis |
US5954766A (en) | 1997-09-16 | 1999-09-21 | Zadno-Azizi; Gholam-Reza | Body fluid flow control device |
US6056722A (en) | 1997-09-18 | 2000-05-02 | Iowa-India Investments Company Limited Of Douglas | Delivery mechanism for balloons, drugs, stents and other physical/mechanical agents and methods of use |
US5984959A (en) | 1997-09-19 | 1999-11-16 | United States Surgical | Heart valve replacement tools and procedures |
US5925063A (en) | 1997-09-26 | 1999-07-20 | Khosravi; Farhad | Coiled sheet valve, filter or occlusive device and methods of use |
US6361545B1 (en) | 1997-09-26 | 2002-03-26 | Cardeon Corporation | Perfusion filter catheter |
US6071308A (en) | 1997-10-01 | 2000-06-06 | Boston Scientific Corporation | Flexible metal wire stent |
IES81060B2 (en) | 1997-11-07 | 2000-01-12 | Salviac Ltd | An embolic protection device |
US6695864B2 (en) | 1997-12-15 | 2004-02-24 | Cardeon Corporation | Method and apparatus for cerebral embolic protection |
JP2002508209A (en) | 1997-12-15 | 2002-03-19 | プロリフィックス メディカル, インコーポレイテッド | Vascular stent for reduction of restenosis |
EP1042045B1 (en) | 1997-12-15 | 2004-05-19 | Domnick Hunter Limited | Filter assembly |
US6530952B2 (en) | 1997-12-29 | 2003-03-11 | The Cleveland Clinic Foundation | Bioprosthetic cardiovascular valve system |
CA2315211A1 (en) | 1997-12-29 | 1999-07-08 | The Cleveland Clinic Foundation | System for minimally invasive insertion of a bioprosthetic heart valve |
US6096074A (en) | 1998-01-27 | 2000-08-01 | United States Surgical | Stapling apparatus and method for heart valve replacement |
US5944738A (en) | 1998-02-06 | 1999-08-31 | Aga Medical Corporation | Percutaneous catheter directed constricting occlusion device |
WO1999039649A1 (en) | 1998-02-10 | 1999-08-12 | Dubrul William R | Occlusion, anchoring, tensioning and flow direction apparatus and methods for use |
EP1054634A4 (en) | 1998-02-10 | 2006-03-29 | Artemis Medical Inc | Entrapping apparatus and method for use |
EP0935978A1 (en) | 1998-02-16 | 1999-08-18 | Medicorp S.A. | Angioplasty and stent delivery catheter |
US6623521B2 (en) | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
US6280467B1 (en) | 1998-02-26 | 2001-08-28 | World Medical Manufacturing Corporation | Delivery system for deployment and endovascular assembly of a multi-stage stented graft |
US5938697A (en) | 1998-03-04 | 1999-08-17 | Scimed Life Systems, Inc. | Stent having variable properties |
US7491232B2 (en) | 1998-09-18 | 2009-02-17 | Aptus Endosystems, Inc. | Catheter-based fastener implantation apparatus and methods with implantation force resolution |
EP0943300A1 (en) | 1998-03-17 | 1999-09-22 | Medicorp S.A. | Reversible action endoprosthesis delivery device. |
US7500988B1 (en) | 2000-11-16 | 2009-03-10 | Cordis Corporation | Stent for use in a stent graft |
US6776791B1 (en) | 1998-04-01 | 2004-08-17 | Endovascular Technologies, Inc. | Stent and method and device for packing of same |
JP2002510524A (en) | 1998-04-02 | 2002-04-09 | サルヴィアック・リミテッド | Implant having a support structure and a transition material comprising a porous plastic material |
US6074418A (en) | 1998-04-20 | 2000-06-13 | St. Jude Medical, Inc. | Driver tool for heart valve prosthesis fasteners |
US6450989B2 (en) | 1998-04-27 | 2002-09-17 | Artemis Medical, Inc. | Dilating and support apparatus with disease inhibitors and methods for use |
US6319241B1 (en) | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
US6059827A (en) | 1998-05-04 | 2000-05-09 | Axya Medical, Inc. | Sutureless cardiac valve prosthesis, and devices and methods for implanting them |
JP4583597B2 (en) | 1998-05-05 | 2010-11-17 | ボストン サイエンティフィック リミテッド | Smooth end stent |
US6352554B2 (en) | 1998-05-08 | 2002-03-05 | Sulzer Vascutek Limited | Prosthetic tubular aortic conduit and method for manufacturing the same |
US6093203A (en) | 1998-05-13 | 2000-07-25 | Uflacker; Renan | Stent or graft support structure for treating bifurcated vessels having different diameter portions and methods of use and implantation |
KR20010052481A (en) | 1998-06-02 | 2001-06-25 | 쿡 인코포레이티드 | Multiple-sided intraluminal medical device |
US7452371B2 (en) | 1999-06-02 | 2008-11-18 | Cook Incorporated | Implantable vascular device |
US6630001B2 (en) | 1998-06-24 | 2003-10-07 | International Heart Institute Of Montana Foundation | Compliant dehyrated tissue for implantation and process of making the same |
AU749930B2 (en) | 1998-07-10 | 2002-07-04 | Shin Ishimaru | Stent (or stent graft) indwelling device |
US6159239A (en) | 1998-08-14 | 2000-12-12 | Prodesco, Inc. | Woven stent/graft structure |
US6179860B1 (en) | 1998-08-19 | 2001-01-30 | Artemis Medical, Inc. | Target tissue localization device and method |
US6312461B1 (en) | 1998-08-21 | 2001-11-06 | John D. Unsworth | Shape memory tubular stent |
US6358276B1 (en) | 1998-09-30 | 2002-03-19 | Impra, Inc. | Fluid containing endoluminal stent |
US6475239B1 (en) | 1998-10-13 | 2002-11-05 | Sulzer Carbomedics Inc. | Method for making polymer heart valves with leaflets having uncut free edges |
US6051014A (en) | 1998-10-13 | 2000-04-18 | Embol-X, Inc. | Percutaneous filtration catheter for valve repair surgery and methods of use |
US6254612B1 (en) | 1998-10-22 | 2001-07-03 | Cordis Neurovascular, Inc. | Hydraulic stent deployment system |
US6146366A (en) | 1998-11-03 | 2000-11-14 | Ras Holding Corp | Device for the treatment of macular degeneration and other eye disorders |
GB2347685B (en) | 1998-11-06 | 2002-12-18 | Furukawa Electric Co Ltd | NiTi-based medical guidewire and method of producing the same |
US6214036B1 (en) | 1998-11-09 | 2001-04-10 | Cordis Corporation | Stent which is easily recaptured and repositioned within the body |
US6336937B1 (en) | 1998-12-09 | 2002-01-08 | Gore Enterprise Holdings, Inc. | Multi-stage expandable stent-graft |
DE19857887B4 (en) | 1998-12-15 | 2005-05-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring support for a heart valve prosthesis |
US6363938B2 (en) | 1998-12-22 | 2002-04-02 | Angiotrax, Inc. | Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth |
FR2788217A1 (en) | 1999-01-12 | 2000-07-13 | Brice Letac | PROSTHETIC VALVE IMPLANTABLE BY CATHETERISM, OR SURGICAL |
US6736845B2 (en) | 1999-01-26 | 2004-05-18 | Edwards Lifesciences Corporation | Holder for flexible heart valve |
DE60044289D1 (en) | 1999-01-27 | 2010-06-10 | Medtronic Inc | DEVICE FOR HEADLAPPING |
US6896690B1 (en) | 2000-01-27 | 2005-05-24 | Viacor, Inc. | Cardiac valve procedure methods and devices |
EP3173035A1 (en) | 1999-02-01 | 2017-05-31 | Board of Regents, The University of Texas System | Woven intravascular devices |
DE60040206D1 (en) | 1999-02-01 | 2008-10-23 | Univ Texas | WOVEN, TWO AND THREE-WAY STENTS AND MANUFACTURING METHOD THEREFOR |
SG148822A1 (en) | 1999-02-01 | 2009-01-29 | Univ Texas | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
US7018401B1 (en) | 1999-02-01 | 2006-03-28 | Board Of Regents, The University Of Texas System | Woven intravascular devices and methods for making the same and apparatus for delivery of the same |
DE19904975A1 (en) | 1999-02-06 | 2000-09-14 | Impella Cardiotech Ag | Device for intravascular heart valve surgery |
US6425916B1 (en) | 1999-02-10 | 2002-07-30 | Michi E. Garrison | Methods and devices for implanting cardiac valves |
US20020138094A1 (en) | 1999-02-12 | 2002-09-26 | Thomas Borillo | Vascular filter system |
DE19907646A1 (en) | 1999-02-23 | 2000-08-24 | Georg Berg | Valve for blood vessels uses flap holders and counterpart holders on stent to latch together in place and all channeled for guide wire. |
US6171327B1 (en) | 1999-02-24 | 2001-01-09 | Scimed Life Systems, Inc. | Intravascular filter and method |
US6905743B1 (en) | 1999-02-25 | 2005-06-14 | Boston Scientific Scimed, Inc. | Dimensionally stable balloons |
US6743196B2 (en) | 1999-03-01 | 2004-06-01 | Coaxia, Inc. | Partial aortic occlusion devices and methods for cerebral perfusion augmentation |
US6231551B1 (en) | 1999-03-01 | 2001-05-15 | Coaxia, Inc. | Partial aortic occlusion devices and methods for cerebral perfusion augmentation |
IL128938A0 (en) | 1999-03-11 | 2000-02-17 | Mind Guard Ltd | Implantable stroke treating device |
US6673089B1 (en) | 1999-03-11 | 2004-01-06 | Mindguard Ltd. | Implantable stroke treating device |
US6319281B1 (en) | 1999-03-22 | 2001-11-20 | Kumar R. Patel | Artificial venous valve and sizing catheter |
US7226467B2 (en) | 1999-04-09 | 2007-06-05 | Evalve, Inc. | Fixation device delivery catheter, systems and methods of use |
US7147663B1 (en) | 1999-04-23 | 2006-12-12 | St. Jude Medical Atg, Inc. | Artificial heart valve attachment apparatus and methods |
WO2000067661A2 (en) | 1999-05-12 | 2000-11-16 | Spence Paul A | Heart valve and apparatus for replacement thereof, blood vessel leak detector and temporary pacemaker lead |
US6309417B1 (en) | 1999-05-12 | 2001-10-30 | Paul A. Spence | Heart valve and apparatus for replacement thereof |
US6858034B1 (en) | 1999-05-20 | 2005-02-22 | Scimed Life Systems, Inc. | Stent delivery system for prevention of kinking, and method of loading and using same |
US6790229B1 (en) | 1999-05-25 | 2004-09-14 | Eric Berreklouw | Fixing device, in particular for fixing to vascular wall tissue |
JP3755862B2 (en) | 1999-05-26 | 2006-03-15 | キヤノン株式会社 | Synchronized position control apparatus and method |
EP1057459A1 (en) | 1999-06-01 | 2000-12-06 | Numed, Inc. | Radially expandable stent |
EP1057460A1 (en) | 1999-06-01 | 2000-12-06 | Numed, Inc. | Replacement valve assembly and method of implanting same |
US7628803B2 (en) | 2001-02-05 | 2009-12-08 | Cook Incorporated | Implantable vascular device |
AU6000200A (en) | 1999-07-16 | 2001-02-05 | Biocompatibles Limited | Braided stent |
US6179859B1 (en) | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
US6312465B1 (en) | 1999-07-23 | 2001-11-06 | Sulzer Carbomedics Inc. | Heart valve prosthesis with a resiliently deformable retaining member |
US6371970B1 (en) | 1999-07-30 | 2002-04-16 | Incept Llc | Vascular filter having articulation region and methods of use in the ascending aorta |
US6544279B1 (en) | 2000-08-09 | 2003-04-08 | Incept, Llc | Vascular device for emboli, thrombus and foreign body removal and methods of use |
US6346116B1 (en) | 1999-08-03 | 2002-02-12 | Medtronic Ave, Inc. | Distal protection device |
US6142987A (en) | 1999-08-03 | 2000-11-07 | Scimed Life Systems, Inc. | Guided filter with support wire and methods of use |
US6235044B1 (en) | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
US6168579B1 (en) | 1999-08-04 | 2001-01-02 | Scimed Life Systems, Inc. | Filter flush system and methods of use |
US6299637B1 (en) | 1999-08-20 | 2001-10-09 | Samuel M. Shaolian | Transluminally implantable venous valve |
US6187016B1 (en) | 1999-09-14 | 2001-02-13 | Daniel G. Hedges | Stent retrieval device |
US6829497B2 (en) | 1999-09-21 | 2004-12-07 | Jamil Mogul | Steerable diagnostic catheters |
IT1307268B1 (en) | 1999-09-30 | 2001-10-30 | Sorin Biomedica Cardio Spa | DEVICE FOR HEART VALVE REPAIR OR REPLACEMENT. |
US6371983B1 (en) | 1999-10-04 | 2002-04-16 | Ernest Lane | Bioprosthetic heart valve |
US6364895B1 (en) | 1999-10-07 | 2002-04-02 | Prodesco, Inc. | Intraluminal filter |
FR2799364B1 (en) | 1999-10-12 | 2001-11-23 | Jacques Seguin | MINIMALLY INVASIVE CANCELING DEVICE |
US6383171B1 (en) | 1999-10-12 | 2002-05-07 | Allan Will | Methods and devices for protecting a passageway in a body when advancing devices through the passageway |
US6352708B1 (en) | 1999-10-14 | 2002-03-05 | The International Heart Institute Of Montana Foundation | Solution and method for treating autologous tissue for implant operation |
AU1084101A (en) | 1999-10-14 | 2001-04-23 | United Stenting, Inc. | Stents with multilayered struts |
US6440164B1 (en) | 1999-10-21 | 2002-08-27 | Scimed Life Systems, Inc. | Implantable prosthetic valve |
US6585758B1 (en) | 1999-11-16 | 2003-07-01 | Scimed Life Systems, Inc. | Multi-section filamentary endoluminal stent |
FR2800984B1 (en) | 1999-11-17 | 2001-12-14 | Jacques Seguin | DEVICE FOR REPLACING A HEART VALVE PERCUTANEOUSLY |
US7018406B2 (en) | 1999-11-17 | 2006-03-28 | Corevalve Sa | Prosthetic valve for transluminal delivery |
FR2815844B1 (en) | 2000-10-31 | 2003-01-17 | Jacques Seguin | TUBULAR SUPPORT FOR THE PERCUTANEOUS POSITIONING OF A REPLACEMENT HEART VALVE |
US8579966B2 (en) | 1999-11-17 | 2013-11-12 | Medtronic Corevalve Llc | Prosthetic valve for transluminal delivery |
US6379383B1 (en) | 1999-11-19 | 2002-04-30 | Advanced Bio Prosthetic Surfaces, Ltd. | Endoluminal device exhibiting improved endothelialization and method of manufacture thereof |
US6458153B1 (en) | 1999-12-31 | 2002-10-01 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US6849085B2 (en) | 1999-11-19 | 2005-02-01 | Advanced Bio Prosthetic Surfaces, Ltd. | Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same |
US7195641B2 (en) | 1999-11-19 | 2007-03-27 | Advanced Bio Prosthetic Surfaces, Ltd. | Valvular prostheses having metal or pseudometallic construction and methods of manufacture |
US6663667B2 (en) | 1999-12-29 | 2003-12-16 | Edwards Lifesciences Corporation | Towel graft means for enhancing tissue ingrowth in vascular grafts |
KR20020082217A (en) | 2000-01-27 | 2002-10-30 | 쓰리에프 쎄러퓨틱스, 인코포레이티드 | Prosthetic Heart Valve |
US6872226B2 (en) | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
US6398807B1 (en) | 2000-01-31 | 2002-06-04 | Scimed Life Systems, Inc. | Braided branching stent, method for treating a lumen therewith, and process for manufacture therefor |
US6622604B1 (en) | 2000-01-31 | 2003-09-23 | Scimed Life Systems, Inc. | Process for manufacturing a braided bifurcated stent |
EP2329796B1 (en) | 2000-01-31 | 2021-09-01 | Cook Biotech Incorporated | Stent valve |
US6652571B1 (en) | 2000-01-31 | 2003-11-25 | Scimed Life Systems, Inc. | Braided, branched, implantable device and processes for manufacture thereof |
US6797002B2 (en) | 2000-02-02 | 2004-09-28 | Paul A. Spence | Heart valve repair apparatus and methods |
WO2001056512A1 (en) | 2000-02-02 | 2001-08-09 | Snyders Robert V | Artificial heart valve |
US6821297B2 (en) | 2000-02-02 | 2004-11-23 | Robert V. Snyders | Artificial heart valve, implantation instrument and method therefor |
US6540768B1 (en) | 2000-02-09 | 2003-04-01 | Cordis Corporation | Vascular filter system |
US6344044B1 (en) | 2000-02-11 | 2002-02-05 | Edwards Lifesciences Corp. | Apparatus and methods for delivery of intraluminal prosthesis |
DE10010074B4 (en) | 2000-02-28 | 2005-04-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Device for fastening and anchoring heart valve prostheses |
DE10010073B4 (en) | 2000-02-28 | 2005-12-22 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring for implantable heart valve prostheses |
KR20020082861A (en) | 2000-03-03 | 2002-10-31 | 쿡 인코포레이티드 | Endovascular device having a stent |
WO2001067989A2 (en) | 2000-03-10 | 2001-09-20 | Don Michael T Anthony | Vascular embolism preventon device employing filters |
US6695865B2 (en) | 2000-03-20 | 2004-02-24 | Advanced Bio Prosthetic Surfaces, Ltd. | Embolic protection device |
US6468303B1 (en) | 2000-03-27 | 2002-10-22 | Aga Medical Corporation | Retrievable self expanding shunt |
US6454799B1 (en) | 2000-04-06 | 2002-09-24 | Edwards Lifesciences Corporation | Minimally-invasive heart valves and methods of use |
GB2369575A (en) | 2000-04-20 | 2002-06-05 | Salviac Ltd | An embolic protection system |
US6729356B1 (en) | 2000-04-27 | 2004-05-04 | Endovascular Technologies, Inc. | Endovascular graft for providing a seal with vasculature |
ATE416718T1 (en) | 2000-05-04 | 2008-12-15 | Univ Oregon Health & Science | ENDOVASCULAR STENT GRAFT |
IL136213A0 (en) | 2000-05-17 | 2001-05-20 | Xtent Medical Inc | Selectively expandable and releasable stent |
US20030083656A1 (en) | 2000-11-07 | 2003-05-01 | George Morrison | Tissue separator assembly and method |
US20050043757A1 (en) | 2000-06-12 | 2005-02-24 | Michael Arad | Medical devices formed from shape memory alloys displaying a stress-retained martensitic state and method for use thereof |
SE522805C2 (en) | 2000-06-22 | 2004-03-09 | Jan Otto Solem | Stent Application System |
US6527800B1 (en) | 2000-06-26 | 2003-03-04 | Rex Medical, L.P. | Vascular device and method for valve leaflet apposition |
US6676698B2 (en) | 2000-06-26 | 2004-01-13 | Rex Medicol, L.P. | Vascular device with valve for approximating vessel wall |
WO2002001999A2 (en) | 2000-06-30 | 2002-01-10 | Viacor, Incorporated | Method and apparatus for performing a procedure on a cardiac valve |
US6419696B1 (en) | 2000-07-06 | 2002-07-16 | Paul A. Spence | Annuloplasty devices and related heart valve repair methods |
US6572643B1 (en) | 2000-07-19 | 2003-06-03 | Vascular Architects, Inc. | Endoprosthesis delivery catheter assembly and method |
JP5178984B2 (en) | 2000-07-24 | 2013-04-10 | グレイゼル、ジェフリー | Stiffening balloon catheter for dilatation and stenting |
US6773454B2 (en) | 2000-08-02 | 2004-08-10 | Michael H. Wholey | Tapered endovascular stent graft and method of treating abdominal aortic aneurysms and distal iliac aneurysms |
US6485501B1 (en) | 2000-08-11 | 2002-11-26 | Cordis Corporation | Vascular filter system with guidewire and capture mechanism |
US6572652B2 (en) | 2000-08-29 | 2003-06-03 | Venpro Corporation | Method and devices for decreasing elevated pulmonary venous pressure |
US6846325B2 (en) | 2000-09-07 | 2005-01-25 | Viacor, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US6543610B1 (en) | 2000-09-12 | 2003-04-08 | Alok Nigam | System for packaging and handling an implant and method of use |
US7510572B2 (en) | 2000-09-12 | 2009-03-31 | Shlomo Gabbay | Implantation system for delivery of a heart valve prosthesis |
US6893459B1 (en) | 2000-09-20 | 2005-05-17 | Ample Medical, Inc. | Heart valve annulus device and method of using same |
WO2004030568A2 (en) | 2002-10-01 | 2004-04-15 | Ample Medical, Inc. | Device and method for repairing a native heart valve leaflet |
US6461382B1 (en) | 2000-09-22 | 2002-10-08 | Edwards Lifesciences Corporation | Flexible heart valve having moveable commissures |
US6602288B1 (en) | 2000-10-05 | 2003-08-05 | Edwards Lifesciences Corporation | Minimally-invasive annuloplasty repair segment delivery template, system and method of use |
DE10049813C1 (en) | 2000-10-09 | 2002-04-18 | Universitaetsklinikum Freiburg | Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion |
DE10049815B4 (en) | 2000-10-09 | 2005-10-13 | Universitätsklinikum Freiburg | Device for local ablation of an aortic valve on the human or animal heart |
DE10049812B4 (en) | 2000-10-09 | 2004-06-03 | Universitätsklinikum Freiburg | Device for filtering out macroscopic particles from the bloodstream during local removal of an aortic valve on the human or animal heart |
DE10049814B4 (en) | 2000-10-09 | 2006-10-19 | Universitätsklinikum Freiburg | Device for supporting surgical procedures within a vessel, in particular for minimally invasive explantation and implantation of heart valves |
US6936058B2 (en) | 2000-10-18 | 2005-08-30 | Nmt Medical, Inc. | Over-the-wire interlock attachment/detachment mechanism |
US6814754B2 (en) | 2000-10-30 | 2004-11-09 | Secant Medical, Llc | Woven tubular graft with regions of varying flexibility |
US6482228B1 (en) | 2000-11-14 | 2002-11-19 | Troy R. Norred | Percutaneous aortic valve replacement |
US7267685B2 (en) | 2000-11-16 | 2007-09-11 | Cordis Corporation | Bilateral extension prosthesis and method of delivery |
US6843802B1 (en) | 2000-11-16 | 2005-01-18 | Cordis Corporation | Delivery apparatus for a self expanding retractable stent |
DE60112603T2 (en) | 2000-11-21 | 2006-06-14 | Rex Medical Lp | PERKUTANE AORTENKLAPPE |
US6974476B2 (en) | 2003-05-05 | 2005-12-13 | Rex Medical, L.P. | Percutaneous aortic valve |
EP1347794A2 (en) | 2000-11-27 | 2003-10-01 | Medtronic, Inc. | Stents and methods for preparing stents from wires having hydrogel coating layers thereon |
US6953332B1 (en) | 2000-11-28 | 2005-10-11 | St. Jude Medical, Inc. | Mandrel for use in forming valved prostheses having polymer leaflets by dip coating |
US6663588B2 (en) | 2000-11-29 | 2003-12-16 | C.R. Bard, Inc. | Active counterforce handle for use in bidirectional deflectable tip instruments |
US6494909B2 (en) | 2000-12-01 | 2002-12-17 | Prodesco, Inc. | Endovascular valve |
ATE310470T1 (en) | 2000-12-15 | 2005-12-15 | Angiomed Ag | STENT WITH HEART VALVE |
US6471708B2 (en) | 2000-12-21 | 2002-10-29 | Bausch & Lomb Incorporated | Intraocular lens and additive packaging system |
US20020120328A1 (en) | 2000-12-21 | 2002-08-29 | Pathak Chandrashekhar Prabhakar | Mechanical heart valve packaged in a liquid |
US6468660B2 (en) | 2000-12-29 | 2002-10-22 | St. Jude Medical, Inc. | Biocompatible adhesives |
WO2002056955A1 (en) | 2001-01-18 | 2002-07-25 | Edwards Lifesciences Corporation | Arterial cannula with perforated filter lumen |
EP1363560A4 (en) | 2001-01-19 | 2007-04-04 | Walid Najib Aboul-Hosn | Apparatus and method for maintaining flow through a vessel or duct |
US6610077B1 (en) | 2001-01-23 | 2003-08-26 | Endovascular Technologies, Inc. | Expandable emboli filter and thrombectomy device |
US6863688B2 (en) | 2001-02-15 | 2005-03-08 | Spinecore, Inc. | Intervertebral spacer device utilizing a spirally slotted belleville washer having radially spaced concentric grooves |
US6623518B2 (en) | 2001-02-26 | 2003-09-23 | Ev3 Peripheral, Inc. | Implant delivery system with interlock |
US20020123755A1 (en) | 2001-03-01 | 2002-09-05 | Scimed Life Systems, Inc. | Embolic protection filter delivery sheath |
US6562058B2 (en) | 2001-03-02 | 2003-05-13 | Jacques Seguin | Intravascular filter system |
US6488704B1 (en) | 2001-05-07 | 2002-12-03 | Biomed Solutions, Llc | Implantable particle measuring apparatus |
WO2002071977A2 (en) | 2001-03-08 | 2002-09-19 | Atritech, Inc. | Atrial filter implants |
US6503272B2 (en) | 2001-03-21 | 2003-01-07 | Cordis Corporation | Stent-based venous valves |
US6733525B2 (en) | 2001-03-23 | 2004-05-11 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of use |
US7374571B2 (en) | 2001-03-23 | 2008-05-20 | Edwards Lifesciences Corporation | Rolled minimally-invasive heart valves and methods of manufacture |
US7556646B2 (en) | 2001-09-13 | 2009-07-07 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US6773456B1 (en) | 2001-03-23 | 2004-08-10 | Endovascular Technologies, Inc. | Adjustable customized endovascular graft |
DE60104647T2 (en) | 2001-03-27 | 2005-08-11 | William Cook Europe Aps | Vascular graft for the aorta |
JP2002293678A (en) | 2001-03-28 | 2002-10-09 | Fuji Photo Film Co Ltd | Method for forming image |
US6911036B2 (en) | 2001-04-03 | 2005-06-28 | Medtronic Vascular, Inc. | Guidewire apparatus for temporary distal embolic protection |
WO2002083224A2 (en) | 2001-04-17 | 2002-10-24 | Salviac Limited | A catheter |
US6837901B2 (en) | 2001-04-27 | 2005-01-04 | Intek Technology L.L.C. | Methods for delivering, repositioning and/or retrieving self-expanding stents |
WO2002087455A1 (en) | 2001-04-27 | 2002-11-07 | C.R. Bard, Inc. | Handle design for a medical catheter |
DE10121210B4 (en) | 2001-04-30 | 2005-11-17 | Universitätsklinikum Freiburg | Anchoring element for the intraluminal anchoring of a heart valve replacement and method for its production |
US6746469B2 (en) | 2001-04-30 | 2004-06-08 | Advanced Cardiovascular Systems, Inc. | Balloon actuated apparatus having multiple embolic filters, and method of use |
US20050021123A1 (en) | 2001-04-30 | 2005-01-27 | Jurgen Dorn | Variable speed self-expanding stent delivery system and luer locking connector |
US7374560B2 (en) | 2001-05-01 | 2008-05-20 | St. Jude Medical, Cardiology Division, Inc. | Emboli protection devices and related methods of use |
US6682558B2 (en) | 2001-05-10 | 2004-01-27 | 3F Therapeutics, Inc. | Delivery system for a stentless valve bioprosthesis |
US6716238B2 (en) | 2001-05-10 | 2004-04-06 | Scimed Life Systems, Inc. | Stent with detachable tethers and method of using same |
US6663663B2 (en) | 2001-05-14 | 2003-12-16 | M.I. Tech Co., Ltd. | Stent |
US6936067B2 (en) | 2001-05-17 | 2005-08-30 | St. Jude Medical Inc. | Prosthetic heart valve with slit stent |
US6821291B2 (en) | 2001-06-01 | 2004-11-23 | Ams Research Corporation | Retrievable stent and method of use thereof |
KR100393548B1 (en) | 2001-06-05 | 2003-08-02 | 주식회사 엠아이텍 | Stent |
EP1392197B1 (en) | 2001-06-08 | 2005-11-16 | Rex Medical, LP | Vascular device with valve for approximating vessel wall |
US7510571B2 (en) | 2001-06-11 | 2009-03-31 | Boston Scientific, Scimed, Inc. | Pleated composite ePTFE/textile hybrid covering |
US6818013B2 (en) | 2001-06-14 | 2004-11-16 | Cordis Corporation | Intravascular stent device |
GB0114918D0 (en) | 2001-06-19 | 2001-08-08 | Vortex Innovation Ltd | Devices for repairing aneurysms |
US7544206B2 (en) | 2001-06-29 | 2009-06-09 | Medtronic, Inc. | Method and apparatus for resecting and replacing an aortic valve |
FR2826863B1 (en) | 2001-07-04 | 2003-09-26 | Jacques Seguin | ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A BODY CONDUIT |
US7547322B2 (en) | 2001-07-19 | 2009-06-16 | The Cleveland Clinic Foundation | Prosthetic valve and method for making same |
FR2828091B1 (en) | 2001-07-31 | 2003-11-21 | Seguin Jacques | ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT |
US6755854B2 (en) | 2001-07-31 | 2004-06-29 | Advanced Cardiovascular Systems, Inc. | Control device and mechanism for deploying a self-expanding medical device |
FR2828263B1 (en) | 2001-08-03 | 2007-05-11 | Philipp Bonhoeffer | DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE |
US6896002B2 (en) | 2001-08-21 | 2005-05-24 | Scimed Life Systems, Inc | Pressure transducer protection valve |
EP1427469A4 (en) | 2001-08-22 | 2007-03-28 | Hasan Semih Oktay | Flexible mems actuated controlled expansion stent |
US7097665B2 (en) | 2003-01-16 | 2006-08-29 | Synecor, Llc | Positioning tools and methods for implanting medical devices |
US20030229390A1 (en) | 2001-09-17 | 2003-12-11 | Control Delivery Systems, Inc. | On-stent delivery of pyrimidines and purine analogs |
US6616682B2 (en) | 2001-09-19 | 2003-09-09 | Jomed Gmbh | Methods and apparatus for distal protection during a medical procedure |
US20030065386A1 (en) | 2001-09-28 | 2003-04-03 | Weadock Kevin Shaun | Radially expandable endoprosthesis device with two-stage deployment |
US7172572B2 (en) | 2001-10-04 | 2007-02-06 | Boston Scientific Scimed, Inc. | Manifold system for a medical device |
US6976974B2 (en) | 2002-10-23 | 2005-12-20 | Scimed Life Systems, Inc. | Rotary manifold syringe |
AU2002347855A1 (en) | 2001-10-09 | 2003-04-22 | Endoscopic Technologies, Inc. | Method and apparatus for improved stiffness in the linkage assembly of a flexible arm |
US6790237B2 (en) | 2001-10-09 | 2004-09-14 | Scimed Life Systems, Inc. | Medical stent with a valve and related methods of manufacturing |
US6893460B2 (en) | 2001-10-11 | 2005-05-17 | Percutaneous Valve Technologies Inc. | Implantable prosthetic valve |
US6866669B2 (en) | 2001-10-12 | 2005-03-15 | Cordis Corporation | Locking handle deployment mechanism for medical device and method |
US6939352B2 (en) | 2001-10-12 | 2005-09-06 | Cordis Corporation | Handle deployment mechanism for medical device and method |
US7192441B2 (en) | 2001-10-16 | 2007-03-20 | Scimed Life Systems, Inc. | Aortic artery aneurysm endovascular prosthesis |
US7144363B2 (en) | 2001-10-16 | 2006-12-05 | Extensia Medical, Inc. | Systems for heart treatment |
AUPR847201A0 (en) | 2001-10-26 | 2001-11-15 | Cook Incorporated | Endoluminal graft |
GB0125925D0 (en) | 2001-10-29 | 2001-12-19 | Univ Glasgow | Mitral valve prosthesis |
US6712843B2 (en) | 2001-11-20 | 2004-03-30 | Scimed Life Systems, Inc | Stent with differential lengthening/shortening members |
US20070073389A1 (en) * | 2001-11-28 | 2007-03-29 | Aptus Endosystems, Inc. | Endovascular aneurysm devices, systems, and methods |
US6890340B2 (en) | 2001-11-29 | 2005-05-10 | Medtronic Vascular, Inc. | Apparatus for temporary intraluminal protection |
US7294146B2 (en) | 2001-12-03 | 2007-11-13 | Xtent, Inc. | Apparatus and methods for delivery of variable length stents |
CA2759746C (en) | 2001-12-05 | 2018-05-22 | Smt Research And Development Ltd. | Endovascular device for entrapment of particulate matter and method for use |
US7041139B2 (en) | 2001-12-11 | 2006-05-09 | Boston Scientific Scimed, Inc. | Ureteral stents and related methods |
US6676668B2 (en) | 2001-12-12 | 2004-01-13 | C.R. Baed | Articulating stone basket |
US7189258B2 (en) | 2002-01-02 | 2007-03-13 | Medtronic, Inc. | Heart valve system |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US20030130729A1 (en) | 2002-01-04 | 2003-07-10 | David Paniagua | Percutaneously implantable replacement heart valve device and method of making same |
US6723116B2 (en) | 2002-01-14 | 2004-04-20 | Syde A. Taheri | Exclusion of ascending/descending aorta and/or aortic arch aneurysm |
US20030135162A1 (en) | 2002-01-17 | 2003-07-17 | Scimed Life Systems, Inc. | Delivery and retrieval manifold for a distal protection filter |
US6730377B2 (en) | 2002-01-23 | 2004-05-04 | Scimed Life Systems, Inc. | Balloons made from liquid crystal polymer blends |
US6911040B2 (en) | 2002-01-24 | 2005-06-28 | Cordis Corporation | Covered segmented stent |
US6689144B2 (en) | 2002-02-08 | 2004-02-10 | Scimed Life Systems, Inc. | Rapid exchange catheter and methods for delivery of vaso-occlusive devices |
US6974464B2 (en) | 2002-02-28 | 2005-12-13 | 3F Therapeutics, Inc. | Supportless atrioventricular heart valve and minimally invasive delivery systems thereof |
EP1482860B1 (en) | 2002-03-05 | 2007-11-14 | Salviac Limited | System with embolic filter and retracting snare |
US20030176884A1 (en) | 2002-03-12 | 2003-09-18 | Marwane Berrada | Everted filter device |
US7163556B2 (en) | 2002-03-21 | 2007-01-16 | Providence Health System - Oregon | Bioprosthesis and method for suturelessly making same |
US20030187495A1 (en) | 2002-04-01 | 2003-10-02 | Cully Edward H. | Endoluminal devices, embolic filters, methods of manufacture and use |
US6752828B2 (en) | 2002-04-03 | 2004-06-22 | Scimed Life Systems, Inc. | Artificial valve |
US7052511B2 (en) | 2002-04-04 | 2006-05-30 | Scimed Life Systems, Inc. | Delivery system and method for deployment of foreshortening endoluminal devices |
US20030195609A1 (en) | 2002-04-10 | 2003-10-16 | Scimed Life Systems, Inc. | Hybrid stent |
AU2003230938A1 (en) | 2002-04-16 | 2003-11-03 | Viacor, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US7125418B2 (en) | 2002-04-16 | 2006-10-24 | The International Heart Institute Of Montana Foundation | Sigmoid valve and method for its percutaneous implantation |
US20030199759A1 (en) | 2002-04-18 | 2003-10-23 | Richard Merwin F. | Coronary catheter with radiopaque length markers |
US8721713B2 (en) | 2002-04-23 | 2014-05-13 | Medtronic, Inc. | System for implanting a replacement valve |
US20030199971A1 (en) | 2002-04-23 | 2003-10-23 | Numed, Inc. | Biological replacement valve assembly |
US20030204249A1 (en) | 2002-04-25 | 2003-10-30 | Michel Letort | Endovascular stent graft and fixation cuff |
AU2003234505A1 (en) | 2002-05-03 | 2003-11-17 | The General Hospital Corporation | Involuted endovascular valve and method of construction |
US8070769B2 (en) | 2002-05-06 | 2011-12-06 | Boston Scientific Scimed, Inc. | Inverted embolic protection filter |
US7141064B2 (en) | 2002-05-08 | 2006-11-28 | Edwards Lifesciences Corporation | Compressed tissue for heart valve leaflets |
US6830575B2 (en) | 2002-05-08 | 2004-12-14 | Scimed Life Systems, Inc. | Method and device for providing full protection to a stent |
JP2005525169A (en) | 2002-05-10 | 2005-08-25 | コーディス・コーポレイション | Method of making a medical device having a thin wall tubular membrane on a structural frame |
US7351256B2 (en) | 2002-05-10 | 2008-04-01 | Cordis Corporation | Frame based unidirectional flow prosthetic implant |
DE10221076A1 (en) | 2002-05-11 | 2003-11-27 | Ruesch Willy Gmbh | stent |
US20030225445A1 (en) | 2002-05-14 | 2003-12-04 | Derus Patricia M. | Surgical stent delivery devices and methods |
US7585309B2 (en) | 2002-05-16 | 2009-09-08 | Boston Scientific Scimed, Inc. | Aortic filter |
US20040117004A1 (en) | 2002-05-16 | 2004-06-17 | Osborne Thomas A. | Stent and method of forming a stent with integral barbs |
WO2003096932A1 (en) | 2002-05-17 | 2003-11-27 | Bionethos Holding Gmbh | Medical device for the treatment of a body vessel or another tubular structure in the body |
EP1513440A2 (en) | 2002-05-30 | 2005-03-16 | The Board of Trustees of The Leland Stanford Junior University | Apparatus and method for coronary sinus access |
US7264632B2 (en) | 2002-06-07 | 2007-09-04 | Medtronic Vascular, Inc. | Controlled deployment delivery system |
US7717934B2 (en) | 2002-06-14 | 2010-05-18 | Ev3 Inc. | Rapid exchange catheters usable with embolic protection devices |
US7044962B2 (en) | 2002-06-25 | 2006-05-16 | Scimed Life Systems, Inc. | Implantable prosthesis with displaceable skirt |
US7166120B2 (en) | 2002-07-12 | 2007-01-23 | Ev3 Inc. | Catheter with occluding cuff |
US7232452B2 (en) | 2002-07-12 | 2007-06-19 | Ev3 Inc. | Device to create proximal stasis |
US7141063B2 (en) | 2002-08-06 | 2006-11-28 | Icon Medical Corp. | Stent with micro-latching hinge joints |
EP1388328A1 (en) | 2002-08-07 | 2004-02-11 | Abbott Laboratories Vascular Enterprises Limited | Apparatus for delivering and deployment of an expandable stent within a blood vessel |
US6969395B2 (en) | 2002-08-07 | 2005-11-29 | Boston Scientific Scimed, Inc. | Electroactive polymer actuated medical devices |
DE10362367B3 (en) | 2002-08-13 | 2022-02-24 | Jenavalve Technology Inc. | Device for anchoring and aligning prosthetic heart valves |
US7041132B2 (en) | 2002-08-16 | 2006-05-09 | 3F Therapeutics, Inc, | Percutaneously delivered heart valve and delivery means thereof |
US6863668B2 (en) | 2002-08-16 | 2005-03-08 | Edwards Lifesciences Corporation | Articulation mechanism for medical devices |
US7175652B2 (en) | 2002-08-20 | 2007-02-13 | Cook Incorporated | Stent graft with improved proximal end |
US8114114B2 (en) | 2002-08-27 | 2012-02-14 | Emboline, Inc. | Embolic protection device |
CA2714875C (en) | 2002-08-28 | 2014-01-07 | Heart Leaflet Technologies, Inc. | Method and device for treating diseased valve |
US7175660B2 (en) | 2002-08-29 | 2007-02-13 | Mitralsolutions, Inc. | Apparatus for implanting surgical devices for controlling the internal circumference of an anatomic orifice or lumen |
US7083633B2 (en) | 2002-09-03 | 2006-08-01 | Advanced Vascular Technologies Llc | Arterial embolic filter deployed from catheter |
KR100442330B1 (en) | 2002-09-03 | 2004-07-30 | 주식회사 엠아이텍 | Stent and manufacturing method the same |
US6875231B2 (en) | 2002-09-11 | 2005-04-05 | 3F Therapeutics, Inc. | Percutaneously deliverable heart valve |
CO5500017A1 (en) | 2002-09-23 | 2005-03-31 | 3F Therapeutics Inc | MITRAL PROTESTIC VALVE |
US20040059409A1 (en) | 2002-09-24 | 2004-03-25 | Stenzel Eric B. | Method of applying coatings to a medical device |
US7998163B2 (en) | 2002-10-03 | 2011-08-16 | Boston Scientific Scimed, Inc. | Expandable retrieval device |
US6824041B2 (en) | 2002-10-21 | 2004-11-30 | Agilent Technologies, Inc. | High temperature eutectic solder ball attach |
EP1553897A1 (en) | 2002-10-24 | 2005-07-20 | Boston Scientific Limited | Venous valve apparatus and method |
US7481823B2 (en) | 2002-10-25 | 2009-01-27 | Boston Scientific Scimed, Inc. | Multiple membrane embolic protection filter |
US6814746B2 (en) | 2002-11-01 | 2004-11-09 | Ev3 Peripheral, Inc. | Implant delivery system with marker interlock |
ES2325249T3 (en) | 2002-11-08 | 2009-08-31 | Jacques Seguin | ENDOVASCULAR PROTESIS FOR A FORK. |
AU2003287638A1 (en) | 2002-11-13 | 2004-06-03 | Rosengart, Todd, K. | Apparatus and method for cutting a heart valve |
EP2345380B1 (en) | 2002-11-13 | 2018-01-10 | Medtronic, Inc. | Cardiac valve procedure devices |
US20040098022A1 (en) | 2002-11-14 | 2004-05-20 | Barone David D. | Intraluminal catheter with hydraulically collapsible self-expanding protection device |
US6887266B2 (en) | 2002-11-14 | 2005-05-03 | Synecor, Llc | Endoprostheses and methods of manufacture |
US7527636B2 (en) | 2002-11-14 | 2009-05-05 | Medtronic Vascular, Inc | Intraluminal guidewire with hydraulically collapsible self-expanding protection device |
US7001425B2 (en) | 2002-11-15 | 2006-02-21 | Scimed Life Systems, Inc. | Braided stent method for its manufacture |
US7485143B2 (en) | 2002-11-15 | 2009-02-03 | Abbott Cardiovascular Systems Inc. | Apparatuses and methods for heart valve repair |
FR2847155B1 (en) | 2002-11-20 | 2005-08-05 | Younes Boudjemline | METHOD FOR MANUFACTURING A MEDICAL IMPLANT WITH ADJUSTED STRUCTURE AND IMPLANT OBTAINED THEREBY |
AU2003283792A1 (en) | 2002-11-29 | 2004-06-23 | Mindguard Ltd. | Braided intraluminal device for stroke prevention |
US7678068B2 (en) | 2002-12-02 | 2010-03-16 | Gi Dynamics, Inc. | Atraumatic delivery devices |
US7025791B2 (en) | 2002-12-02 | 2006-04-11 | Gi Dynamics, Inc. | Bariatric sleeve |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US6984242B2 (en) | 2002-12-20 | 2006-01-10 | Gore Enterprise Holdings, Inc. | Implantable medical device assembly |
US6945957B2 (en) | 2002-12-30 | 2005-09-20 | Scimed Life Systems, Inc. | Valve treatment catheter and methods |
US6830585B1 (en) | 2003-01-14 | 2004-12-14 | 3F Therapeutics, Inc. | Percutaneously deliverable heart valve and methods of implantation |
US20040138694A1 (en) | 2003-01-15 | 2004-07-15 | Scimed Life Systems, Inc. | Intravascular filtering membrane and method of making an embolic protection filter device |
US7753945B2 (en) | 2003-01-17 | 2010-07-13 | Gore Enterprise Holdings, Inc. | Deployment system for an endoluminal device |
WO2004066876A1 (en) | 2003-01-27 | 2004-08-12 | Medtronic Vascular Connaught | Improved packaging for stent delivery systems |
GB2398245B (en) | 2003-02-06 | 2007-03-28 | Great Ormond Street Hospital F | Valve prosthesis |
US7740644B2 (en) | 2003-02-24 | 2010-06-22 | Boston Scientific Scimed, Inc. | Embolic protection filtering device that can be adapted to be advanced over a guidewire |
WO2004078065A2 (en) | 2003-03-03 | 2004-09-16 | Sinus Rhythm Technologies, Inc. | Electrical conduction block implant device |
US7399315B2 (en) | 2003-03-18 | 2008-07-15 | Edwards Lifescience Corporation | Minimally-invasive heart valve with cusp positioners |
US7682389B2 (en) | 2003-03-20 | 2010-03-23 | Aortech International Plc | Cardiac valve featuring a parabolic function |
US20060271081A1 (en) | 2003-03-30 | 2006-11-30 | Fidel Realyvasquez | Apparatus and methods for valve repair |
US7871434B2 (en) | 2003-04-01 | 2011-01-18 | Cook Incorporated | Percutaneously deployed vascular valves |
US7530995B2 (en) | 2003-04-17 | 2009-05-12 | 3F Therapeutics, Inc. | Device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
US7175656B2 (en) | 2003-04-18 | 2007-02-13 | Alexander Khairkhahan | Percutaneous transcatheter heart valve replacement |
US7591832B2 (en) | 2003-04-24 | 2009-09-22 | Medtronic, Inc. | Expandable guide sheath and apparatus with distal protection and methods for use |
EP1472996B1 (en) | 2003-04-30 | 2009-09-30 | Medtronic Vascular, Inc. | Percutaneously delivered temporary valve |
US6969396B2 (en) | 2003-05-07 | 2005-11-29 | Scimed Life Systems, Inc. | Filter membrane with increased surface area |
US7235093B2 (en) | 2003-05-20 | 2007-06-26 | Boston Scientific Scimed, Inc. | Mechanism to improve stent securement |
US20040243221A1 (en) | 2003-05-27 | 2004-12-02 | Fawzi Natalie V. | Endovascular graft including substructure for positioning and sealing within vasculature |
US7625364B2 (en) | 2003-05-27 | 2009-12-01 | Cardia, Inc. | Flexible center connection for occlusion device |
DE602004029159D1 (en) | 2003-05-28 | 2010-10-28 | Cook Inc | |
US7041127B2 (en) | 2003-05-28 | 2006-05-09 | Ledergerber Walter J | Textured and drug eluting coronary artery stent |
WO2005004753A1 (en) | 2003-06-09 | 2005-01-20 | 3F Therapeutics, Inc. | Atrioventricular heart valve and minimally invasive delivery systems thereof |
BRPI0412362A (en) | 2003-07-08 | 2006-09-05 | Ventor Technologies Ltd | prosthetic implant devices particularly for transarterial transport in the treatment of aortic stenoses and implantation methods for such devices |
US7201772B2 (en) | 2003-07-08 | 2007-04-10 | Ventor Technologies, Ltd. | Fluid flow prosthetic device |
US7744620B2 (en) | 2003-07-18 | 2010-06-29 | Intervalve, Inc. | Valvuloplasty catheter |
AU2004258942B2 (en) | 2003-07-21 | 2009-12-03 | The Trustees Of The University Of Pennsylvania | Percutaneous heart valve |
DE10334868B4 (en) | 2003-07-29 | 2013-10-17 | Pfm Medical Ag | Implantable device as a replacement organ valve, its manufacturing process and basic body and membrane element for it |
WO2005011535A2 (en) | 2003-07-31 | 2005-02-10 | Cook Incorporated | Prosthetic valve for implantation in a body vessel |
EP1659992B1 (en) | 2003-07-31 | 2013-03-27 | Cook Medical Technologies LLC | Prosthetic valve devices and methods of making such devices |
DE10340265A1 (en) | 2003-08-29 | 2005-04-07 | Sievers, Hans-Hinrich, Prof. Dr.med. | Prosthesis for the replacement of the aortic and / or mitral valve of the heart |
US20050049692A1 (en) | 2003-09-02 | 2005-03-03 | Numamoto Michael J. | Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation |
WO2005023358A1 (en) | 2003-09-03 | 2005-03-17 | Acumen Medical, Inc. | Expandable sheath for delivering instruments and agents into a body lumen |
US8535344B2 (en) | 2003-09-12 | 2013-09-17 | Rubicon Medical, Inc. | Methods, systems, and devices for providing embolic protection and removing embolic material |
US7758625B2 (en) | 2003-09-12 | 2010-07-20 | Abbott Vascular Solutions Inc. | Delivery system for medical devices |
US7993384B2 (en) | 2003-09-12 | 2011-08-09 | Abbott Cardiovascular Systems Inc. | Delivery system for medical devices |
EG24012A (en) | 2003-09-24 | 2008-03-23 | Wael Mohamed Nabil Lotfy | Valved balloon stent |
US10219899B2 (en) | 2004-04-23 | 2019-03-05 | Medtronic 3F Therapeutics, Inc. | Cardiac valve replacement systems |
EP1684671B1 (en) | 2003-10-06 | 2020-09-30 | Medtronic 3F Therapeutics, Inc. | Minimally invasive valve replacement system |
US20050075712A1 (en) | 2003-10-06 | 2005-04-07 | Brian Biancucci | Minimally invasive valve replacement system |
CA2541970A1 (en) | 2003-10-09 | 2005-06-09 | E.I. Du Pont De Nemours And Company | Gene silencing by using micro-rna molecules |
WO2005037338A1 (en) | 2003-10-14 | 2005-04-28 | Cook Incorporated | Hydrophilic coated medical device |
DE602004026756D1 (en) | 2003-10-15 | 2010-06-02 | Cook Inc | HOLDING DEVICE FOR A PROSTHESIS SYSTEM |
US7175654B2 (en) | 2003-10-16 | 2007-02-13 | Cordis Corporation | Stent design having stent segments which uncouple upon deployment |
US7004176B2 (en) | 2003-10-17 | 2006-02-28 | Edwards Lifesciences Ag | Heart valve leaflet locator |
US7419498B2 (en) | 2003-10-21 | 2008-09-02 | Nmt Medical, Inc. | Quick release knot attachment system |
US7070616B2 (en) | 2003-10-31 | 2006-07-04 | Cordis Corporation | Implantable valvular prosthesis |
US7347869B2 (en) | 2003-10-31 | 2008-03-25 | Cordis Corporation | Implantable valvular prosthesis |
WO2005048883A1 (en) | 2003-11-13 | 2005-06-02 | Fidel Realyvasquez | Methods and apparatus for valve repair |
US6972025B2 (en) | 2003-11-18 | 2005-12-06 | Scimed Life Systems, Inc. | Intravascular filter with bioabsorbable centering element |
US7186265B2 (en) | 2003-12-10 | 2007-03-06 | Medtronic, Inc. | Prosthetic cardiac valves and systems and methods for implanting thereof |
US20050137683A1 (en) | 2003-12-19 | 2005-06-23 | Medtronic Vascular, Inc. | Medical devices to treat or inhibit restenosis |
US7261732B2 (en) | 2003-12-22 | 2007-08-28 | Henri Justino | Stent mounted valve |
US20050137686A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical, A Delaware Corporation | Externally expandable heart valve anchor and method |
US8182528B2 (en) | 2003-12-23 | 2012-05-22 | Sadra Medical, Inc. | Locking heart valve anchor |
US8343213B2 (en) | 2003-12-23 | 2013-01-01 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US9526609B2 (en) | 2003-12-23 | 2016-12-27 | Boston Scientific Scimed, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US7329279B2 (en) | 2003-12-23 | 2008-02-12 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8579962B2 (en) | 2003-12-23 | 2013-11-12 | Sadra Medical, Inc. | Methods and apparatus for performing valvuloplasty |
US8603160B2 (en) | 2003-12-23 | 2013-12-10 | Sadra Medical, Inc. | Method of using a retrievable heart valve anchor with a sheath |
US20120041550A1 (en) | 2003-12-23 | 2012-02-16 | Sadra Medical, Inc. | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements |
US7988724B2 (en) | 2003-12-23 | 2011-08-02 | Sadra Medical, Inc. | Systems and methods for delivering a medical implant |
US7381219B2 (en) | 2003-12-23 | 2008-06-03 | Sadra Medical, Inc. | Low profile heart valve and delivery system |
US8840663B2 (en) | 2003-12-23 | 2014-09-23 | Sadra Medical, Inc. | Repositionable heart valve method |
US7748389B2 (en) | 2003-12-23 | 2010-07-06 | Sadra Medical, Inc. | Leaflet engagement elements and methods for use thereof |
US7824442B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US7959666B2 (en) | 2003-12-23 | 2011-06-14 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a heart valve |
US20050137694A1 (en) | 2003-12-23 | 2005-06-23 | Haug Ulrich R. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US8828078B2 (en) | 2003-12-23 | 2014-09-09 | Sadra Medical, Inc. | Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements |
US8287584B2 (en) | 2005-11-14 | 2012-10-16 | Sadra Medical, Inc. | Medical implant deployment tool |
US20050137696A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Apparatus and methods for protecting against embolization during endovascular heart valve replacement |
PT2749254E (en) | 2003-12-23 | 2015-10-16 | Boston Scient Scimed Inc | Repositionable heart valve |
US20050137691A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Two piece heart valve and anchor |
AU2004308508B2 (en) | 2003-12-23 | 2011-03-10 | Sadra Medical, Inc. | Repositionable heart valve |
US7824443B2 (en) | 2003-12-23 | 2010-11-02 | Sadra Medical, Inc. | Medical implant delivery and deployment tool |
US7445631B2 (en) | 2003-12-23 | 2008-11-04 | Sadra Medical, Inc. | Methods and apparatus for endovascularly replacing a patient's heart valve |
US20050137687A1 (en) | 2003-12-23 | 2005-06-23 | Sadra Medical | Heart valve anchor and method |
US7780725B2 (en) | 2004-06-16 | 2010-08-24 | Sadra Medical, Inc. | Everting heart valve |
US9005273B2 (en) | 2003-12-23 | 2015-04-14 | Sadra Medical, Inc. | Assessing the location and performance of replacement heart valves |
US20050228495A1 (en) | 2004-01-15 | 2005-10-13 | Macoviak John A | Suspended heart valve devices, systems, and methods for supplementing, repairing, or replacing a native heart valve |
US7468070B2 (en) | 2004-01-23 | 2008-12-23 | Boston Scientific Scimed, Inc. | Stent delivery catheter |
US7597711B2 (en) | 2004-01-26 | 2009-10-06 | Arbor Surgical Technologies, Inc. | Heart valve assembly with slidable coupling connections |
US20050203818A9 (en) | 2004-01-26 | 2005-09-15 | Cibc World Markets | System and method for creating tradeable financial units |
CA2556077C (en) | 2004-02-05 | 2012-05-01 | Children's Medical Center Corporation | Transcatheter delivery of a replacement heart valve |
US7311730B2 (en) | 2004-02-13 | 2007-12-25 | Shlomo Gabbay | Support apparatus and heart valve prosthesis for sutureless implantation |
CA2813136A1 (en) | 2004-02-27 | 2005-09-15 | Aortx, Inc. | Prosthetic heart valve delivery systems and methods |
ITTO20040135A1 (en) | 2004-03-03 | 2004-06-03 | Sorin Biomedica Cardio Spa | CARDIAC VALVE PROSTHESIS |
WO2005086888A2 (en) | 2004-03-09 | 2005-09-22 | Fidel Realyvasquez | Off pump aortic valve replacement for valve prosthesis |
EP2308425B2 (en) | 2004-03-11 | 2023-10-18 | Percutaneous Cardiovascular Solutions Pty Limited | Percutaneous Heart Valve Prosthesis |
CA2561188A1 (en) | 2004-03-31 | 2005-10-20 | Med Institute, Inc. | Endoluminal graft with a prosthetic valve |
EP1737390A1 (en) | 2004-04-08 | 2007-01-03 | Cook Incorporated | Implantable medical device with optimized shape |
WO2005102015A2 (en) | 2004-04-23 | 2005-11-03 | 3F Therapeutics, Inc. | Implantable prosthetic valve |
EP1600121B1 (en) | 2004-05-25 | 2007-07-18 | William Cook Europe ApS | Stent and stent retrieval system |
WO2005118019A1 (en) | 2004-05-28 | 2005-12-15 | Cook Incorporated | Implantable bioabsorbable valve support frame |
US7122020B2 (en) | 2004-06-25 | 2006-10-17 | Mogul Enterprises, Inc. | Linkage steering mechanism for deflectable catheters |
US7276078B2 (en) | 2004-06-30 | 2007-10-02 | Edwards Lifesciences Pvt | Paravalvular leak detection, sealing, and prevention |
US7462191B2 (en) | 2004-06-30 | 2008-12-09 | Edwards Lifesciences Pvt, Inc. | Device and method for assisting in the implantation of a prosthetic valve |
US8500785B2 (en) | 2004-07-13 | 2013-08-06 | Boston Scientific Scimed, Inc. | Catheter |
FR2874813B1 (en) | 2004-09-07 | 2007-06-22 | Perouse Soc Par Actions Simpli | VALVULAR PROSTHESIS |
US6951571B1 (en) | 2004-09-30 | 2005-10-04 | Rohit Srivastava | Valve implanting device |
US7641687B2 (en) | 2004-11-02 | 2010-01-05 | Carbomedics Inc. | Attachment of a sewing cuff to a heart valve |
US20060161249A1 (en) | 2004-11-22 | 2006-07-20 | Fidel Realyvasquez | Ring-shaped valve prosthesis attachment device |
US7989157B2 (en) | 2005-01-11 | 2011-08-02 | Medtronic, Inc. | Solution for storing bioprosthetic tissue used in a biological prosthesis |
ITTO20050074A1 (en) | 2005-02-10 | 2006-08-11 | Sorin Biomedica Cardio Srl | CARDIAC VALVE PROSTHESIS |
US7918880B2 (en) | 2005-02-16 | 2011-04-05 | Boston Scientific Scimed, Inc. | Self-expanding stent and delivery system |
DK1850796T3 (en) | 2005-02-18 | 2016-01-18 | Cleveland Clinic Foundation | DEVICE FOR REPLACEMENT OF A HEART VALVE |
US7722666B2 (en) | 2005-04-15 | 2010-05-25 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
US7914569B2 (en) | 2005-05-13 | 2011-03-29 | Medtronics Corevalve Llc | Heart valve prosthesis and methods of manufacture and use |
JP4912395B2 (en) | 2005-05-24 | 2012-04-11 | エドワーズ ライフサイエンシーズ コーポレイション | Rapid placement prosthetic heart valve |
CN101991478B (en) | 2005-05-27 | 2013-04-24 | 心叶科技公司 | Stentless support structure |
US7938851B2 (en) | 2005-06-08 | 2011-05-10 | Xtent, Inc. | Devices and methods for operating and controlling interventional apparatus |
US20060287668A1 (en) | 2005-06-16 | 2006-12-21 | Fawzi Natalie V | Apparatus and methods for intravascular embolic protection |
WO2007005799A1 (en) | 2005-06-30 | 2007-01-11 | Abbott Laboratories | Delivery system for a medical device |
US8968379B2 (en) | 2005-09-02 | 2015-03-03 | Medtronic Vascular, Inc. | Stent delivery system with multiple evenly spaced pullwires |
US7712606B2 (en) | 2005-09-13 | 2010-05-11 | Sadra Medical, Inc. | Two-part package for medical implant |
US20080188928A1 (en) | 2005-09-16 | 2008-08-07 | Amr Salahieh | Medical device delivery sheath |
EP1945129A2 (en) | 2005-09-30 | 2008-07-23 | Incept, LLC | Apparatus and methods for locating an ostium of a vessel |
DE102005052628B4 (en) | 2005-11-04 | 2014-06-05 | Jenavalve Technology Inc. | Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter |
EP1991168B1 (en) | 2006-02-16 | 2016-01-27 | Transcatheter Technologies GmbH | Minimally invasive heart valve replacement |
WO2007130881A2 (en) | 2006-04-29 | 2007-11-15 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
AU2007261046A1 (en) | 2006-06-20 | 2007-12-27 | Aortx, Inc. | Torque shaft and torque drive |
US20080033541A1 (en) | 2006-08-02 | 2008-02-07 | Daniel Gelbart | Artificial mitral valve |
US8876895B2 (en) | 2006-09-19 | 2014-11-04 | Medtronic Ventor Technologies Ltd. | Valve fixation member having engagement arms |
JP5106537B2 (en) | 2006-09-28 | 2012-12-26 | ハート リーフレット テクノロジーズ, インコーポレイテッド | Delivery tool for transdermal delivery of prostheses |
EP3329860A1 (en) | 2006-11-07 | 2018-06-06 | David Stephen Celermajer | Devices for the treatment of heart failure |
WO2008073214A2 (en) | 2006-12-08 | 2008-06-19 | Boston Scientific Limited | Therapeutic catheter with displacement sensing transducer |
US8236045B2 (en) | 2006-12-22 | 2012-08-07 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method of making the same |
EP2129332B1 (en) | 2007-02-16 | 2019-01-23 | Medtronic, Inc. | Replacement prosthetic heart valves |
US7753949B2 (en) | 2007-02-23 | 2010-07-13 | The Trustees Of The University Of Pennsylvania | Valve prosthesis systems and methods |
US8070802B2 (en) | 2007-02-23 | 2011-12-06 | The Trustees Of The University Of Pennsylvania | Mitral valve system |
US9138315B2 (en) | 2007-04-13 | 2015-09-22 | Jenavalve Technology Gmbh | Medical device for treating a heart valve insufficiency or stenosis |
US20080294230A1 (en) * | 2007-05-24 | 2008-11-27 | Cook Incorporated | Apparatus and methods for deploying self-expanding stents |
ES2375426T3 (en) | 2007-06-26 | 2012-02-29 | St. Jude Medical, Inc. | APPLIANCE FOR THE IMPLEMENTATION OF REPLIGABLE / EXPANSIBLE PROTESTIC HEART VALVES. |
US8828079B2 (en) | 2007-07-26 | 2014-09-09 | Boston Scientific Scimed, Inc. | Circulatory valve, system and method |
US8827082B2 (en) | 2007-08-02 | 2014-09-09 | Montrose Technologies Inc. | Apparatus for inspecting and sorting articles traveling on a conveyor |
US8192351B2 (en) | 2007-08-13 | 2012-06-05 | Paracor Medical, Inc. | Medical device delivery system having integrated introducer |
EP2185107B1 (en) | 2007-09-07 | 2017-01-25 | Edwards Lifesciences Corporation | Active holder for annuloplasty ring delivery |
EP2222247B1 (en) | 2007-11-19 | 2012-08-22 | Cook Medical Technologies LLC | Valve frame |
US20090171456A1 (en) | 2007-12-28 | 2009-07-02 | Kveen Graig L | Percutaneous heart valve, system, and method |
US8157853B2 (en) | 2008-01-24 | 2012-04-17 | Medtronic, Inc. | Delivery systems and methods of implantation for prosthetic heart valves |
US8317858B2 (en) | 2008-02-26 | 2012-11-27 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8398704B2 (en) | 2008-02-26 | 2013-03-19 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US8052607B2 (en) | 2008-04-22 | 2011-11-08 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ultrasound imaging catheter with pivoting head |
US8696743B2 (en) | 2008-04-23 | 2014-04-15 | Medtronic, Inc. | Tissue attachment devices and methods for prosthetic heart valves |
EP3967274B1 (en) | 2008-04-23 | 2022-08-24 | Medtronic, Inc. | Stented heart valve devices |
US8323335B2 (en) | 2008-06-20 | 2012-12-04 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves and methods for using |
US8652202B2 (en) | 2008-08-22 | 2014-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US9192497B2 (en) | 2008-09-05 | 2015-11-24 | Cook Medical Technologies Llc | Apparatus and methods for improved stent deployment |
EP3753534A1 (en) | 2008-09-29 | 2020-12-23 | Edwards Lifesciences CardiAQ LLC | Heart valve |
CA2739275C (en) | 2008-10-01 | 2017-01-17 | Impala, Inc. | Delivery system for vascular implant |
EP3238661B1 (en) | 2008-10-10 | 2019-05-22 | Boston Scientific Scimed, Inc. | Medical devices and delivery systems for delivering medical devices |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
EP2201911B1 (en) | 2008-12-23 | 2015-09-30 | Sorin Group Italia S.r.l. | Expandable prosthetic valve having anchoring appendages |
US9402720B2 (en) | 2009-01-12 | 2016-08-02 | Valve Medical Ltd. | Modular percutaneous valve structure and delivery method |
US20100217382A1 (en) | 2009-02-25 | 2010-08-26 | Edwards Lifesciences | Mitral valve replacement with atrial anchoring |
JP5659168B2 (en) | 2009-02-27 | 2015-01-28 | セント・ジュード・メディカル,インコーポレイテッド | Foldable prosthetic heart valve stent features |
US9980818B2 (en) | 2009-03-31 | 2018-05-29 | Edwards Lifesciences Corporation | Prosthetic heart valve system with positioning markers |
CA2961053C (en) | 2009-04-15 | 2019-04-30 | Edwards Lifesciences Cardiaq Llc | Vascular implant and delivery system |
AU2010315030B2 (en) | 2009-11-05 | 2016-03-10 | The Trustees Of The University Of Pennsylvania | Valve prosthesis |
EP2509538B1 (en) | 2009-12-08 | 2017-09-20 | Avalon Medical Ltd. | Device and system for transcatheter mitral valve replacement |
DE102010008360A1 (en) | 2010-02-17 | 2011-09-29 | Transcatheter Technologies Gmbh | Medical implant in which gaps remain during crimping or folding, method and device for moving |
WO2011109813A2 (en) | 2010-03-05 | 2011-09-09 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US8623079B2 (en) | 2010-04-23 | 2014-01-07 | Medtronic, Inc. | Stents for prosthetic heart valves |
US9744031B2 (en) | 2010-05-25 | 2017-08-29 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
CA2835893C (en) | 2011-07-12 | 2019-03-19 | Boston Scientific Scimed, Inc. | Coupling system for medical devices |
US9119716B2 (en) | 2011-07-27 | 2015-09-01 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
EP4289398A3 (en) | 2011-08-11 | 2024-03-13 | Tendyne Holdings, Inc. | Improvements for prosthetic valves and related inventions |
US20130123796A1 (en) | 2011-11-15 | 2013-05-16 | Boston Scientific Scimed, Inc. | Medical device with keyed locking structures |
CA3201836A1 (en) | 2011-12-09 | 2013-06-13 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
EP2793748B1 (en) | 2011-12-20 | 2017-02-22 | Boston Scientific Scimed, Inc. | Apparatus for endovascularly replacing a heart valve |
US9277993B2 (en) | 2011-12-20 | 2016-03-08 | Boston Scientific Scimed, Inc. | Medical device delivery systems |
US10172708B2 (en) | 2012-01-25 | 2019-01-08 | Boston Scientific Scimed, Inc. | Valve assembly with a bioabsorbable gasket and a replaceable valve implant |
CN104487022B (en) | 2012-05-09 | 2017-03-29 | 波士顿科学国际有限公司 | The valve of the reduction profile with locking member |
US9259315B2 (en) | 2012-07-12 | 2016-02-16 | Boston Scientific Scimed, Inc. | Low profile heart valve delivery system and method |
EP2900327B1 (en) | 2012-09-25 | 2017-11-15 | Koninklijke Philips N.V. | A treatment device and a treatment system |
CN110338911B (en) | 2014-03-10 | 2022-12-23 | 坦迪尼控股股份有限公司 | Apparatus and method for positioning and monitoring tether load of prosthetic mitral valve |
US9757232B2 (en) | 2014-05-22 | 2017-09-12 | Edwards Lifesciences Corporation | Crimping apparatus for crimping prosthetic valve with protruding anchors |
US9788942B2 (en) | 2015-02-03 | 2017-10-17 | Boston Scientific Scimed Inc. | Prosthetic heart valve having tubular seal |
US10342660B2 (en) | 2016-02-02 | 2019-07-09 | Boston Scientific Inc. | Tensioned sheathing aids |
US11826522B2 (en) | 2016-06-01 | 2023-11-28 | Becton, Dickinson And Company | Medical devices, systems and methods utilizing permanent magnet and magnetizable feature |
-
2019
- 2019-01-21 US US16/253,010 patent/US11246625B2/en active Active
- 2019-01-21 JP JP2020539804A patent/JP7047106B2/en active Active
- 2019-01-21 WO PCT/US2019/014408 patent/WO2019144071A1/en unknown
- 2019-01-21 EP EP19703919.1A patent/EP3740170A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050149159A1 (en) * | 2003-12-23 | 2005-07-07 | Xtent, Inc., A Delaware Corporation | Devices and methods for controlling and indicating the length of an interventional element |
WO2016100799A1 (en) * | 2014-12-18 | 2016-06-23 | Medtronic Inc. | Transcatheter prosthetic heart valve delivery system with clinician feedback |
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US20190223909A1 (en) | 2019-07-25 |
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