Connect public, paid and private patent data with Google Patents Public Datasets

Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion

Info

Publication number
DE10049813C1
Authority
DE
Grant status
Grant
Patent type
Prior art keywords
cutting
cap
tool
end
far
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE2000149813
Other languages
German (de)
Inventor
Ulrich Matern
Peter Waller
Georg Berg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaetsklinikum Freiburg
Original Assignee
Universitaetsklinikum Freiburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320783Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22097Valve removal in veins

Abstract

The instrument for a local scraping of the aortic valve, in a human or animal heart, is a hollow catheter to be inserted into the aorta artery and is flexible at least at the far end. The far end carries a cutter, which has a fluid-tight closure cap (5) with at least one opening (6) defined by a cutting edge (7). A cutting tool (8) has a linear or rotating movement within the cap, with a cutting edge (10) moving against the cap cutting edge. The zone (11) around the cutting tool is linked towards the near end of the catheter. The zone (12) at the far side of the cutting tool is enclosed by it and the closure cap, and it is filled with a gas or fluid and/or a mechanical expansion system as the drive for the cutting tool. The cutting tool is of a ceramic or light metal alloy material.

Description

Technisches Gebiet technical field

Die Erfindung bezieht sich auf eine Vorrichtung zum lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz. The invention relates to a device for the local removal of an aortic valve on the human or animal heart.

Stand der Technik State of the art

Bei einer Vielzahl von Patienten kommt es vor, dass sich im Laufe der Zeit irreversible Ablagerungen an der Herzklappe bilden, insbesondere an der Aortenklappe, häufig in Form von Kalkablagerungen oder sonstigen Materialdepositionen. In a large number of patients, it happens that form irreversible deposits on the heart valve over time, particularly at the aortic valve, often in the form of calcium deposits or other material deposition. Durch derartige Materialablagerungen an der Aortenklappe, die in einem gesunden Zustand als ein feines flexibles Gewebesegel ausgebildet ist, kommt es zu einer irreversiblen Versteifung der Aortenklappe, wodurch insbesondere der Blutabfluss aus dem Herzen erheblich in Mitleidenschaft gezogen wird. By such material deposits on the aortic valve, which is designed as a fine flexible fabric sail in a healthy condition, there is an irreversible stiffening of the aortic valve, whereby in particular the flow of blood is drawn from the heart significantly affected. Blutunterversorgung im gesamten Körper ist die Folge, so dass in einem derart fortgeschrittenen Stadium akuter Handlungsbedarf besteht, will man schwerwiegende Folgen für den Patienten vermeiden. Low blood supply throughout the body is the result, so that there is in such an advanced stage of acute need for action, we want to avoid serious consequences for the patient. Bisher bekannte medikamentöse Behandlungsmethoden zeigen jedoch nur begrenzten Erfolg, so dass nach heutiger Kenntnis eine Verkalkung von Aortenklappen lediglich durch einen schwerwiegenden chirurgischen Eingriff begegnet werden kann. However, previously known drug treatments show limited success, so now known to calcification of the aortic valve can be countered only by a serious surgical procedure. Üblicherweise wird in diesem Fall im Rahmen einer Sternotomie der Brustkorb eines Menschen geöffnet um Zugang zum Herz und insbesondere zu den verkalkten Aortenklappen zu erhalten, die mit bekannten Schneidewerkzeugen aus dem Körper extrahiert werden. Usually, the chest of a man is opened to access the heart and in particular to the calcified aortic valves to obtain in this case as part of a sternotomy, which are extracted with known cutting tools from the body. Beispielsweise eignen sich hierzu Extraktionswerkzeuge wie sie in den amerikanischen Druckschriften US 6,033,419 sowie US 5,827,316 beschrieben sind. For example, this suitable extraction tools as described in the American documents US 6,033,419 and US 5,827,316. Nach erfolgtem operativen Eingriff und Wiederverschluss des Brustkorbes steht dem Patienten eine langwierige Heilungsdauer bevor, die in den meisten Fällen von einer ebenso langwierigen Rehabilitationszeit gefolgt ist. After the surgery and re-closure of the thorax the patient is facing a lengthy healing period that is followed in most cases by an equally lengthy rehabilitation period.

Aus der US 5,720,760 geht eine Resektionsvorrichtung hervor mit einem kanülenartig ausgebildeten Schneidkopf mit zwei relativ beweglichen Schnittkanten, doch ist diese Resektionsvorrichtung nicht zum Aortenabtrag geeignet zumal die Ansteuerung wenigstens einer Schnittkante über eine geradlinig starre Verbindung vom proximalen Ende der Kanülenanordnung aus erfolgt. From US 5,720,760 a resection is apparent with a cannula-like cutting head with two relatively movable cutting edges, but this resection device is not suitable for Aortenabtrag since the control is executed at least one cutting edge via a straight rigid connection from the proximal end of the cannula assembly. Eine deratige Anordnung kann aufgrund der Starrheit nicht durch das Gefäßsystem zur Aortenklappe geführt werden. A deratige arrangement can not be passed through the vascular system to the aortic valve because of the rigidity.

Bislang sind keine Möglichkeiten bekannt, die Entfernung einer verkalkten Aortenklappe unter Umgehung der vorstehend genannten Sternotomie durchzuführen. So far no ways are known to carry out the removal of a calcified aortic valve by bypassing the aforementioned sternotomy.

Darstellung der Erfindung Summary of the Invention

Der Erfindung liegt daher die Aufgabe zugrunde, eine Vorrichtung zum lokalen Abtrag einer verkalkten Aortenklappe am menschlichen oder tierischen Herz derart auszubilden, so dass ein chirurgischer Eingriff minimal invasiv durchgeführt werden kann, ohne die vorstehend genannten Nachteile bei der Sternotomie in Kauf nehmen zu müssen. The invention is therefore based on the object to form a device for the local removal of a calcified aortic valve on the human or animal heart in such a way so that a surgical procedure can be performed in a minimally invasive, without taking the above-mentioned disadvantages in the sternotomy into account. Es gilt insbesondere eine Vorrichtung anzugeben, mit der es möglich ist, eine verkalkte Aortenklappe sicher und schonend zu entfernen, ohne dabei die Herztätigkeit während des minimal invasiven Eingriffes in Mitleidenschaft zu ziehen. It applies in particular to provide a device with which it is possible to remove a calcified aortic valve safely and gently, without pulling the heart activity during the minimally invasive procedure affected.

Die Lösung der der Erfindung zugrunde liegende Aufgabe ist im Anspruch 1 angegeben. The solution of the problem underlying the invention is indicated in claim. 1 den Lösungsgedanken vorteilhaft weiterbildende Merkmale sind Gegenstand der Unteransprüche sowie der Beschreibung unter Bezugnahme auf die Ausführungsbeispiele zu entnehmen. the solution thought advantageously further features can be found in the subject of the dependent claims and the description with reference to the embodiments.

Erfindungsgemäß ist eine Vorrichtung zum lokalen Abtrag einer Aortenklappe vorzugsweise am menschlichen Körper derart ausgebildet, dass ein Hohlkatheter vorgesehen ist, der zumindest im distalen Bereich flexibel ausgebildet ist und sich durch intrakorporales Einbringen in den Aortenbogen dem natürlichen Verlauf des Aortenbogens anpasst. According to the invention a device for the local removal of an aortic valve is preferably designed in such a way on the human body, that a hollow catheter is provided which is flexible at least in the distal area and adapts by intracorporeal introduction into the aortic arch to the natural curve of the aortic arch. Am distalen Ende des Hohlkatheters ist eine Schervorrichtung vorgesehen, die eine fluiddicht mit dem Hohlkatheter verbundene Abschlusskappe vorsieht, die wenigstens eine Öffnung mit wenigstens einer die Öffnung begrenzenden Schneidkante aufweist. At the distal end of the hollow catheter, a shearing apparatus is provided which provides a fluid-tight manner to the hollow catheter associated end cap having at least one opening with at least one opening defining a cutting edge. Schließlich ist innerhalb der Abschlusskappe linear- oder drehbeweglich gelagert ein Schneidwerkzeug mit einer Schnittkante vorgesehen, die gegen die Schneidkante der Abschlusskante bewegbar ist. Finally, it is provided within the end cap linear or rotatably mounted a cutting tool with a cutting edge which is movable against the cutting edge of the end edge. Schließlich ist ein von dem Schneidwerkzeug umgebendes Volumen vorgesehen, das mit dem Hohlkatheter proximalwärts verbunden ist. Finally, a bounding volume of the cutting tool is provided, which is connected to the hollow catheter proximally. Um das Schneidwerkzeug innerhalb der Abschlusskappe auszulenken, schließen das Schneidwerkzeug und die Abschlusskappe einem distalseitig angeordneten Raumbereich ein, in dem ein Antriebsmodul vorgesehen ist, das aus einem Gas, einer Flüssigkeit befüllt und/oder aus einem mechanischen Expansionsmittel besteht. To deflect the cutting tool within the end cap, the cutting tool and the end cap include a distally disposed region of space in which a drive module is provided which is filled from a gas, a liquid and / or of a mechanical expansion means.

Mit dem erfindungsgemäß ausgebildeten Werkzeug ist es möglich, den Hohlkatheter über einen Schnitt im Leistenbereich eines Patienten über entsprechende intrakorporale Gefäßkanäle in die Aorta einzuführen und dem Aortaverlauf folgend die Schervorrichtung an der verkalkten Aortenklappe zu positionieren. With the inventive design tool, it is possible to insert the hollow catheter through an incision in the groin area of ​​a patient via corresponding intracorporeal vascular channels in the aorta and the aorta to position following the course of the shearing device to the calcified aortic valve. Hierzu ist der Hohlkatheter insbesondere im distalen Bereich flexibel ausgebildet, so dass der Hohlkatheter mit seinem distalen Ende ohne dabei den natürlichen Verlauf der Aorta zu schädigen oder gar zu verformen unmittelbar im Bereich der verkalkten Aortaklappe positioniert werden kann. For this purpose, the hollow catheter is particularly designed to be flexible in the distal region, so that the hollow catheter with its distal end without damaging the natural course of the aorta or deform even can be positioned directly in the region of the calcified aortic valve. Zu Zwecken der Navigation sowie Positionierung des Katheters innerhalb des menschlichen oder tierischen Gefäßes ist der Hohlkatheter mit geeigneten Seilzugvorrichtungen ausgestattet, die innerhalb des Hohlkatheters über entsprechend vorgesehene Kanäle verlaufen. For purposes of navigation and positioning of the catheter within the vessel of the human or animal hollow catheter is equipped with suitable devices cable extending within the hollow catheter over appropriately provided channels. Die Seilzüge können proximalseits entsprechend von einem geeignet geschulten Personal bedient werden. The cables can be operated in accordance proximalseits by a suitably trained personnel. Ferner dienen dillatierbare Volumen in Form von ballonartigen Gebilden, die an der Außenwand des Hohlkatheters angebracht sind und über entsprechende Zuleitungen dillatiert werden können, ebenso zu Zwecken der Navigation und Positionierung, Zentrierung und Fixierung. Further serve dillatierbare volume in the form of balloon-like structures, which are attached to the outer wall of the hollow catheter and can be dillatiert via corresponding leads, also for purposes of navigation and positioning, centering and fixing. So sind Hohlkatheterlängen von einem Meter und mehr durchaus denkbar und üblich, doch bemisst sich die Länge grundsätzlich nach der Körpergröße des zu behandelnde Patienten. Thus, hollow catheter lengths of one meter and more conceivable and customary, but the length depend in principle on the body size of the patient to be treated.

Die Positionierung und Navigation des distalen Endes des Hohlkatheters erfolgt vorzugsweise unter Röntgenbeobachtung oder mit geeigneten ähnlichen Beobachtungstechniken, so dass die Katheterspitze exakt im Bereich der verkalkten Aortenklappe positioniert werden kann. The positioning and navigation of the distal end of the hollow catheter is preferably performed under fluoroscopic observation or by appropriate similar observation techniques so that the catheter tip can be accurately positioned in the area of ​​the calcified aortic valve.

Die erfindungsgemäß ausgebildete Schervorrichtung soll anhand der nachstehenden Figuren näher erläutert werden. The inventively constructed shearing device will be explained with reference to the following figures.

Kurze Beschreibung der Erfindung Summary of the Invention

Die Erfindung wird nachstehend ohne Beschränkung des allgemeinen Erfindungsgedankens anhand von Ausführungsbeispielen unter Bezugnahme auf die Zeichnung exemplarisch beschrieben. The invention is described below, without limiting the general inventive idea with reference to embodiments with reference to the accompanying drawing. Es zeigen: Show it:

Fig. 1 schematisierte, perspektivische Darstellung des Hohlkatheters, Fig. 1 shows a schematic, perspective view of the hollow catheter,

Fig. 2 Querschnitt durch das distale Ende der Schervorrichtung sowie Fig. 2 cross-section through the distal end of the shearing device, and

Fig. 3 schematisierte Gesamtdarstellung der Vorrichtung. Fig. 3 schematic overall view of the device.

Wege zur Ausführung der Erfindung, gewerbliche Verwendbarkeit WAYS OF IMPLEMENTING THE INVENTION, INDUSTRIAL APPLICABILITY

In Fig. 1 ist eine schematisierte, perspektivische Darstellung des Hohlkatheters 1 dargestellt. In Fig. 1 is a schematic, perspective view of the hollow catheter 1 is shown. Die Figur gestattet einen perspektivischen. The figure shows a perspective permitted. Einblick in das Innere des proximalseitigen Endes des Hohlkatheters 1 , an dessen distalen Ende die Schervorrichtung 2 vorgesehen ist. Insight into the interior of the proximal end of the hollow catheter 1, the cutter 2 is provided at its distal end. Um den Hohlkatheter 1 in das entsprechende Aortengefäß einzuführen und das distale Ende mit der Schervorrichtung 2 gezielt an den Ort der Aortenklappe zu navigieren, sind innerhalb des Hohlkatheters 1 Navigationsseilzüge 3 vorgesehen, die proximalseitig von einer Bedienperson entsprechend betätigt werden. In order to introduce the hollow catheter 1 in the corresponding Aortengefäß and navigate the distal end of the cutter 2 targeted to the site of the aortic valve, are provided within the hollow catheter 1 Navigation cables 3, which are proximally actuated accordingly by an operator. Zu Zwecken der genauen Positionierung des Hohlkatheters innerhalb der Aorta sind im distalen Bereich des Hohlkatheters 1 zusätzliche, aufblasbare Ballone 4 vorgesehen, die die Schervorrichtung 2 inmitten der Aorta zu zentrierten vermögen. For purposes of the precise positioning of the hollow catheter within the aorta additional inflatable balloons 4 are provided in the distal portion of the hollow catheter 1 which are capable of the cutter 2 in the middle of the aorta to centered. Nicht dargestellt sind die Zuleitungen zum Befüllen der Ballone, die vorzugsweise ebenso wie die Navigationsseilzüge 3 innerhalb des Hohlkatheters 1 verlaufen. Not shown are the feed lines to the filling of the balloons, which preferably extend as well as the navigation cables 3 within the hollow catheter 1 is.

In der Querschnittsdarstellung gemäß Fig. 2 ist die Schervorrichtung 2 detaillierter dargestellt. In the cross-sectional view of FIG. 2, the cutter 2 is shown in more detail. Die Schervorrichtung 2 weist eine Abschlusskappe 5 auf, die fluiddicht mit dem Hohlkatheter 1 an ihrem proximalseitigen Ende verbunden ist (nicht in Fig. 2 dargestellt). The cutter 2 has an end cap 5, the fluid-tight to the hollow catheter 1 at its proximal end is connected (not shown in Fig. 2). Die Abschlusskappe 5 weist eine Öffnung 6 auf, deren proximal Öffnungsseite eine Schneidkante 7 vorsieht. The end cap 5 has an opening 6, the proximal opening side provides a cutting edge. 7 Im Inneren der Abschlusskappe 5 ist ein längsbewegliches Schneidwerkzeug 8 vorgesehen (siehe Doppelpfeil bezüglich seiner Längsbeweglichkeit), das ebenso wie die Abschlusskappe 5 eine Öffnung 9 vorsieht. Inside the end cap 5, a longitudinally movable cutting tool 8 is provided (see double arrow with respect to its longitudinal mobility), providing as well as the end cap 5 has an opening. 9 Die Öffnung 9 des Schneidwerkzeuges 8 entspricht in ihrer Geometrie und Größe der Öffnung 6 der Abschlussklappe 5 . The opening 9 of the cutting tool 8 corresponds in its geometry and size of the opening 6 of the closing flap. 5 Beide Öffnungen 9 und 6 weisen eine Öffnungsweite w von etwa 3-10 mm auf und sehen eine Öffnungstiefe t in der gleichen Größenordnung vor. Both openings 9 and 6 have an opening width w of about 3-10 mm and see an opening depth t in the same order before. Das Schneidwerkzeug 8 weist an seiner distalen Öffnungsseite eine schart ausgebildete Schnittkante 10 auf, die gleichsam wie die Schneidkante 7 spitz ausgebildet ist. The cutting tool 8 has at its distal opening side to a sharply edged cut 10, which is, as such, the cutting edge 7 is formed sharply. Ferner umschließt das Schneidwerkzeug 8 ein inneres Volumen 11 , das lediglich über die Öffnungen 9 offen ausgebildet ist. Further, the cutting tool 8 encloses an interior volume 11 which is designed to be open only through the openings. 9

Das Schneidwerkzeug 8 ist innerhalb der Abschlusskappe 5 längsbeweglich koaxial zur gedachten Längsachse des Hohlkatheters 1 angeordnet, so dass das Schneidwerkzeug 8 wechselweise distal- und proximalseitig derart bewegbar ist, so dass die Schnittkante 10 des Schneidwerkzeuges 8 unterhalb der Schneidkante 7 der Aschlusskappe 5 gelangen kann, wodurch das Volumen 11 vollständig eingeschlossen ist. The cutting tool 8 is longitudinally movable within the end cap 5 is arranged coaxially to the imaginary longitudinal axis of the hollow catheter 1, so that the cutting tool 8 is distal and proximal movable in such a manner alternately, so that the cut edge 10 of the cutting tool 8 may pass below the cutting edge 7 of the Aschlusskappe 5, whereby the volume 11 is completely enclosed.

Um das Schneidwerkzeug 8 innerhalb der Abschlusskappe 5 in der vorstehend beschriebenen Weise auszulenken, schließen das Schneidwerkzeug 8 und die Abschlusskappe 5 ein distalseitig angeordnetes Volumen (Raumbereich) 12 ein, in dem ein Antriebsmodul vorgesehen sein kann. To deflect the cutter 8 within the end cap 5 in the manner described above, the cutting tool 8 and the end cap 5 include a distal side disposed volume (space region) 12 in which a drive module can be provided. So ist es zum einen möglich, innerhalb des Volumens 12 Gas einzubringen, das durch lokale Erhitzung expandiert und das Schneidwerkzeug 8 proximalwärts bewegt. Thus, it is firstly possible to introduce gas 12 within the volume that is expanded by local heating and the cutting tool 8 is moved proximally. Der Energieeintrag kann beispielsweise mit Hilfe eines Lasers erfolgen, dessen Licht auf die Außenwand der Abschlusskappe 5 gerichtet ist und diese lokal erhitzt oder direkt in den Hohlraum 12 eingebracht werden. The energy input can be carried out, the light is directed to the outer wall of the end cap 5 and these are locally heated or incorporated directly into the cavity 12, for example with the aid of a laser. Laserlicht kann beispielsweise mit geeigneter Kathetertechnik an die vorstehend beschriebene Stelle der Abschlusskappe geleitet werden. Laser light can be directed, for example, with suitable catheter technology to the above-described location of the endcap. Andere Formen der Energieeinbringung sind denkbar. Other forms of energy input are conceivable.

Ferner ist es möglich innerhalb des Volumens 12 Flüssigkeit einzubringen, die über einen entsprechend, nicht dargestellten Zuleitungskanal durch den Hohlkatheter 1 extrakorporal zugeführt werden kann. Further, it is possible to introduce liquid 12 within the volume that can be supplied extracorporeally through a corresponding not shown supply channel through the hollow catheter. 1 Durch entsprechendes Anlegen einer schwingenden Flüssigkeitssäule innerhalb des Zuleitungskanals, die in dem Volumen 12 mündet, kann das Schneidwerkzeug 8 gezielt innerhalb der Abschlusskappe 5 ausgelenkt werden. By appropriately applying an oscillating column of liquid within the feed channel, which opens into the volume 12, the cutting tool 8 may be selectively deflected within the end cap. 5

Schließlich ist es denkbar, ein mechanisches Expansionsmittel, beispielsweise eine Feder innerhalb des Volumens 12 einzubringen, die über entsprechende Wirkmechanismen entspannt und komprimiert werden kann. Finally, it is conceivable, a mechanical expansion means such as a spring to bring within the volume 12, which can be relaxed and compressed via respective mechanisms of action.

Befindet sich das Schneidwerkzeug 2 im Bereich einer verkalkten Aortaklappe, so ist das Schneidwerkzeug derart relativ zur Aortaklappe zu positionieren, dass zumindest Teile der Aortaklappe in das Innere der Öffnungen 6 und 9 hineinragen. The cutting tool 2 is in the area of a calcified aortic valve, as the cutting tool is to be positioned in such a way relative to the aortic valve, that at least portions of the aortic valve protrude into the interior of the openings 6 and the ninth In diesem Fall wird wie vorstehend beschrieben, das Schneidwerkzeug 8 proximalwärts getrieben, wodurch die Schnittkante 10 gegen die Schneidkante 7 getrieben wird und das innerhalb des Volumens 11 hineinragende Teil der Aortaklappe gezielt abgeschnitten werden kann. In this case, the cutting tool 8 is as described above, proximally driven, whereby the cutting edge 10 is driven against the cutting edge 7 and the protruding part 11 inside the volume of the aortic valve can be selectively cut off. Der abgeschnittene Teil der Klappe gelangt nun über das Volumen 11 in das Innere des Hohlkanals 1 und kann durch entsprechende Absaugtechnik extrakorporal verbracht werden. The truncated portion of the flap now passes over the volume 11 in the interior of the hollow duct 1 and can be brought extracorporeally by appropriate extraction technology. Um zu vermeiden, dass Material aus dem Volumen 11 aus der Schervorrichtung austritt, ist proximalseitig am Schneidwerkzeug 8 ein Flatterventil 13 vorgesehen, das einen entsprechenden Rückfluss unterbindet. In order to avoid that material flows from the volume 11 from the shearing apparatus, a flutter valve 13 is provided proximal to the cutting tool 8, which prevents an appropriate reflux. Überdies dient das Flatterventil 13 auch als Anschlagfläche zum distalseitigen Verschieben des Schneidwerkzeugs 8 bspw. mittels Impulswellen oder einem Flüssigkeitsstrom, den man proximalseits zum Flatterventil anlegt Moreover, the reed valve 13 also serves as a stop surface for the distal displacement of the cutting tool 8, for example. By means of pulse waves or a liquid stream, which one applies to the flutter valve proximalseits

Mit Hilfe der in Fig. 2 dargestellten Schervorrichtung ist es möglich, die verkalkte Aortaklappe stückweise abzuschneiden und die abgeschnittenen Teile extrakorporal sicher zu verbringen. Using the shearing device illustrated in Fig. 2, it is possible to cut off the calcified aortic valve piecewise and to spend the cut pieces extracorporeally safely.

Vorzugsweise ist das Schneidwerkzeug 8 aus leichtem Material gefertigt, beispielsweise aus Keramik (lange scharfe Kante), um eine möglichst trägheitsfreie Bewegung des Schneidwerkzeuges 8 zu gewährleisten. Preferably, the cutting tool 8 is made of lightweight material, such as ceramic (long sharp edge), in order to ensure inertia-free as possible movement of the cutting tool. 8

In Fig. 3 ist der gesamte Hohlkatheter 1 mit der erfindungsgemäß ausgebildeten Schervorrichtung 2 dargestellt. In Fig. 3 the entire hollow catheter 1 is shown with the inventive design shear device 2. Proximalseitig zum Hohlkatheter 1 befinden sich Manipulationsvorrichtungen M zum Betätigen des Hohlkatheters zu Zwecken seiner Einführung in die Aorta. Proximal to the hollow catheter 1 are manipulation devices M for actuating the hollow catheter for purposes of its introduction into the aorta. Zusätzlich sind ein Spülbehälter 14 sowie ein Auffanggefäß 15 vorgesehen, um einen gezielten Transport von abgetrennten Gewebematerial aus dem Hohlkatheter 1 zu gewährleisten. In addition, a washing container 14 as well as a collecting vessel 15 are provided in order to ensure a targeted transport of detached tissue material out of the hollow catheter. 1

Der Hohlkatheter selbst ist vorzugsweise aus Kunststoffmaterial gefertigt, das über hochflexible Eigenschaften verfügt, so dass sich ein leichtes Anschmiegen des Hohlkatheters 1 beispielsweise an den Aortenbogen ergibt. The hollow catheter itself is preferably made of plastic material which has highly flexible characteristics, so that a light nestling of the hollow catheter 1, for example, results in the aortic arch.

Die Schervorrichtung 2 ist vorzugsweise auswechselbar über einen Konektor 16 mit dem distalen Ende des Hohlkatheters 1 verbindbar. The cutter 2 is preferably exchangeable on a Konektor 16 to the distal end of the hollow catheter 1 can be connected. Auf diese Weise ist es möglich, bei Verschleiß der Schnitt- und Schneidkante die Schervorrichtung 2 vom Hohlkatheter 1 zu trennen und entsprechend auszuwechseln. In this way, it is possible to separate in case of wear of the cutting and the cutting edge, the cutter 2 from the hollow catheter 1 and replaced according to.

Bezugszeichenliste LIST OF REFERENCE NUMBERS

1 1

Hohlkatheter hollow catheter

2 2

Schervorrichtung shearing device

3 3

Navigationsseilzüge Navigation cables

4 4

Ballon balloon

5 5

Abschlusskappe end cap

6 6

Öffnung opening

7 7

Schneidkante cutting edge

8 8th

Schneidwerkzeug cutting tool

9 9

Öffnung opening

10 10

Schnittkante cutting edge

11 11

Volumen volume

12 12

Volumen (Raumbereich) Volume (space area)

13 13

Flatterventil flutter valve

14 14

Behälter mit Spülflüssigkeit Container with rinsing liquid

15 15

Auffanggefäß collecting vessel

16 16

Konektor Konektor

Claims (11)

1. Vorrichtung zum lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit 1. A device for the local removal of an aortic valve on the human or animal heart with
einem Hohlkatheter ( 1 ), der zumindest im distalen Bereich flexibel ausgebildet ist und durch intrakorporales Einbringen in den Aortenbogen sich dem natürlichen Verlauf des Aortenbogens anpaßt, a hollow catheter (1) is flexible at least in the distal region and conforming by intracorporeal introduction into the aortic arch to the natural curve of the aortic arch,
einer am distalen Ende des Hohlkatheters ( 1 ) vorgesehenen Schervorrichtung ( 2 ), die eine fluiddicht mit dem Hohlkatheter ( 1 ) verbundene Abschlußkappe ( 5 ) vorsieht, die wenigstens die Öffnung ( 6 ) mit wenigstens einer, die Öffnung ( 6 ) begrenzenden Schneidkante ( 7 ) aufweist, a distal end of the hollow catheter (1) provided for shearing device (2) having a fluid-tight manner to the hollow catheter (1) connected to the end cap (5) provides for (the limiting at least the opening (6) with at least one opening (6) cutting edge 7)
mit einem innerhalb der Abschlußkappe ( 5 ) linear- oder drehbeweglich gelagerten Schneidwerkzeug ( 8 ) mit einer Schnittkante ( 10 ), die gegen die Schneidkante ( 7 ) der Abschlußkappe ( 5 ) bewegbar ist, sowie ein von dem Schneidwerkzeug ( 8 ) umgebendes Volumen ( 11 ), das mit dem Hohlkatheter ( 1 ) proximalwärts verbunden ist und linear- with an inside of the end cap (5) or rotatably mounted cutting tool (8) with a cutting edge (10) which is movable against the cutting edge (7) of the end cap (5), and a from the cutting tool (8) surrounding volume ( 11) (with the hollow catheter 1) is connected proximally and
mit einem Raumbereich ( 12 ), der distalseits zum Schneidwerkzeug ( 8 ) von diesem und der Abschlußkappe ( 5 ) einschlossen ist, der mit Gas oder einer Flüssigkeit befüllt und/oder mit einem mechanischen Expansionsmittel versehen ist und als Antrieb zur Bewegung des Schneidwerkzeuges ( 8 ) dient. with a space portion (12), which is which included distalseits to the cutting tool (8) of the latter and the end cap (5), which is filled with gas or a liquid and / or provided with a mechanical expansion means, and (as a drive for moving the cutting tool 8 ) is used.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, dass der Hohlkatheter ( 1 ) eine Länge aufweist, die einer Gefäßlänge zwischen der Leiste und dem Herzen eines Menschen entspricht. 2. Device according to claim 1, characterized in that the hollow catheter (1) has a length corresponding to one tube length between the strip and the heart of a human.
3. Vorrichtung nach Anspruch 1 oder 2, dadurch gekennzeichnet, das innerhalb des Hohlkatheters ( 1 ) und/oder an er Außenwand des Hohlkatheters ( 1 ) Mittel zur Positionierung des Hohlkatheters ( 1 ) innerhalb eines Gefäßes vorgesehen sind. 3. Device according to claim 1 or 2, characterized in that the means for positioning the hollow catheter (1) are provided within a vessel within the hollow catheter (1) and / or on he outer wall of the hollow catheter (1).
4. Vorrichtung nach Anspruch 3, dadurch gekennzeichnet, dass die Mittel zur Navigation Seilzüge ( 3 ) oder dillatierbare Volumina sind. 4. The device according to claim 3, characterized in that the means for navigation cables (3) or dillatierbare volumes.
5. Vorrichtung nach einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, dass das Schneidwerkzeug ( 8 ) innerhalb der Abschlußkappe wechselseitig distal- und proximalwärts zum Hohlkatheter ( 1 ) bewegbar ist. 5. The device is movable according to one of claims 1 to 4, characterized in that the cutting tool (8) within the end cap mutually distal and proximally to the hollow catheter (1).
6. Vorrichtung nach Anspruch 5, dadurch gekennzeichnet, dass das Schneidwerkzeug ( 8 ) eine Schneidöffnung ( 9 ) vorsieht, an deren distalseits orientierter Offnungsseite die Schnittkante ( 10 ) vorgesehen ist, dass die Schneidkante ( 7 ) der Öffnung ( 6 ) in der Abschlußkappe ( 5 ) an ihrer proximalseits orientierten Öffnungsseite angebracht ist, und dass bei Bewegung des Schneidwerkzeuges ( 8 ) Schnittkante ( 10 ) und Schneidkante ( 7 ) einander passieren. 6. The device according to claim 5, characterized in that the cutting tool (8) provides a cutting opening (9) is provided at its distalseits oriented opening side, the cutting edge (10), that the cutting edge (7) of the opening (6) in the end cap (5) is attached to its proximalseits oriented opening side, and that on movement of the cutting tool (8) cutting edge (10) and cutting edge (7) pass each other.
7. Vorrichtung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass das von dem Schneidwerkzeug ( 8 ) umgebende Volumen ( 11 ) über eine Ventilanordnung mit dem Hohlkatheter ( 1 ) proximalwärts verbunden ist. 7. Device according to one of claims 1 to 6, characterized in that the of the cutting tool (8) surrounding volume (11) via a valve arrangement to the hollow catheter (1) is connected proximally.
8. Vorrichtung nach einem der Ansprüche 1 bis 7, dadurch gekennzeichnet, dass die Öffnung ( 9 ) des Schneidwerkzeugs ( 8 ) sowie die Öffnung ( 6 ) der Abschlußkappe ( 5 ) in etwa eine gleiche Öffnungsweite sowie -tiefe aufweisen, dh einen gleichen Öffnungsabstand in Richtung einer gedachten Hohlkatheterlängsachse sowie eine gleiche Öffnungstiefe in Richtung senkrecht zur gedachten Hohlkatheterlängsachse. 8. Device according to one of claims 1 to 7, characterized in that the opening (9) of the cutting tool (8) and the opening (6) of the end cap (5) have the same opening width as well as depth approximately, that is, a same opening distance in direction of an imaginary hollow catheter longitudinal axis and an equal opening depth in the direction perpendicular to the imaginary longitudinal axis of the hollow catheter.
9. Vorrichtung nach Anspruch 8, dadurch gekennzeichnet, dass die Öffnungsweite sowie -tiefe im Bereich zwischen 3 bis 10 mm liegen. 9. Apparatus according to claim 8, characterized in that the opening width and depth in the range between 3 to 10 mm.
10. Vorrichtung nach einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, dass das Gas mittels Energieeintrag expandiert, die Flüssigkeit mittels einer schwingenden Flüssigkeitssäule auslenkbar ist und das mechanische Expansionsmittel mechanisch auslenkbar ist. 10. Device according to one of claims 1 to 9, characterized in that the gas expands means of energy input, the liquid is deflected by an oscillating liquid column and the mechanical expansion means is mechanically deflectable.
11. Vorrichtung nach einem der Ansprüche 1 bis 10, dadurch gekennzeichnet, dass das Schneidwerkzeugs ( 8 ) aus Keramik, aus einer leichten Metallegierung oder aus Titan gefertigt ist. 11. Device according to one of claims 1 to 10, characterized in that the cutting tool (8) made of ceramic, of a light metal alloy or is made of titanium.
DE2000149813 2000-10-09 2000-10-09 Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion Expired - Fee Related DE10049813C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE2000149813 DE10049813C1 (en) 2000-10-09 2000-10-09 Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2000149813 DE10049813C1 (en) 2000-10-09 2000-10-09 Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion

Publications (1)

Publication Number Publication Date
DE10049813C1 true DE10049813C1 (en) 2002-04-18

Family

ID=7659062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2000149813 Expired - Fee Related DE10049813C1 (en) 2000-10-09 2000-10-09 Instrument for the local removal of built-up matter at an aortic valve, in a human or animal heart, is a hollow catheter with a cutting unit at the far end within a closure cap for minimum invasion

Country Status (1)

Country Link
DE (1) DE10049813C1 (en)

Cited By (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7252682B2 (en) 2001-07-04 2007-08-07 Corevalve, S.A. Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US7462191B2 (en) 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7846203B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Implanting a stent valve prosthesis at the native aortic valve
US7871436B2 (en) 2007-02-16 2011-01-18 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US8080054B2 (en) 2003-10-02 2011-12-20 Edwards Lifesciences Corporation Implantable prosthetic valve with non-laminar flow
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
EP2455115A1 (en) 2010-11-19 2012-05-23 Persat, Jean-Charles Sampling carrier for tissue, in particular adipose
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US8236049B2 (en) 2008-06-20 2012-08-07 Edwards Lifesciences Corporation Multipiece prosthetic mitral valve and method
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252051B2 (en) 2009-02-25 2012-08-28 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8460368B2 (en) 2008-02-29 2013-06-11 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8709077B2 (en) 2000-04-06 2014-04-29 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9114008B2 (en) 2006-12-22 2015-08-25 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method for making the same
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9132006B2 (en) 2001-10-11 2015-09-15 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US9241788B2 (en) 2001-03-23 2016-01-26 Edwards Lifesciences Corporation Method for treating an aortic valve
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US9320598B2 (en) 2003-03-18 2016-04-26 Edwards Lifesciences Corporation Method of implanting a self-expandable prosthetic heart valve
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US9393110B2 (en) 2010-10-05 2016-07-19 Edwards Lifesciences Corporation Prosthetic heart valve
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9510942B2 (en) 2007-12-14 2016-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9636221B2 (en) 2007-09-26 2017-05-02 St. Jude Medical, Inc. Collapsible prosthetic heart valves
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US9675449B2 (en) 2008-07-15 2017-06-13 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022737A1 (en) * 1995-01-23 1996-08-01 Houser Russell A Atherectomy catheter and rf cutting method
US5720760A (en) * 1996-04-01 1998-02-24 Linvatec Corporation Endoscopic or open lipectomy instrument
US5827316A (en) * 1997-06-05 1998-10-27 Atrion Medical Products, Inc. Rotating aortic punch
US6033419A (en) * 1998-05-15 2000-03-07 Sulzer Carbomedics Inc. Apparatus and method for cutting a heart valve annulus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022737A1 (en) * 1995-01-23 1996-08-01 Houser Russell A Atherectomy catheter and rf cutting method
US5720760A (en) * 1996-04-01 1998-02-24 Linvatec Corporation Endoscopic or open lipectomy instrument
US5827316A (en) * 1997-06-05 1998-10-27 Atrion Medical Products, Inc. Rotating aortic punch
US6033419A (en) * 1998-05-15 2000-03-07 Sulzer Carbomedics Inc. Apparatus and method for cutting a heart valve annulus

Cited By (212)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846203B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Implanting a stent valve prosthesis at the native aortic valve
US9095432B2 (en) 1996-12-31 2015-08-04 Edwards Lifesciences Pvt, Inc. Collapsible prosthetic valve having an internal cover
US9486312B2 (en) 1996-12-31 2016-11-08 Edwards Lifesciences Pvt, Inc. Method of manufacturing a prosthetic valve
US9629714B2 (en) 1996-12-31 2017-04-25 Edwards Lifesciences Pvt, Inc. Collapsible prosthetic valve
USRE45865E1 (en) 1999-11-17 2016-01-26 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8801779B2 (en) 1999-11-17 2014-08-12 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8986329B2 (en) 1999-11-17 2015-03-24 Medtronic Corevalve Llc Methods for transluminal delivery of prosthetic valves
US8998979B2 (en) 1999-11-17 2015-04-07 Medtronic Corevalve Llc Transcatheter heart valves
US9060856B2 (en) 1999-11-17 2015-06-23 Medtronic Corevalve Llc Transcatheter heart valves
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8721708B2 (en) 1999-11-17 2014-05-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8603159B2 (en) 1999-11-17 2013-12-10 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8709077B2 (en) 2000-04-06 2014-04-29 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US8092487B2 (en) 2000-06-30 2012-01-10 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8777980B2 (en) 2000-06-30 2014-07-15 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US9707074B2 (en) 2001-03-23 2017-07-18 Edwards Lifesciences Corporation Method for treating an aortic valve
US9241788B2 (en) 2001-03-23 2016-01-26 Edwards Lifesciences Corporation Method for treating an aortic valve
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US8628570B2 (en) 2001-07-04 2014-01-14 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US8002826B2 (en) 2001-07-04 2011-08-23 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US7252682B2 (en) 2001-07-04 2007-08-07 Corevalve, S.A. Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9572663B2 (en) 2001-09-13 2017-02-21 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9539091B2 (en) 2001-09-13 2017-01-10 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9572664B2 (en) 2001-09-13 2017-02-21 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9452046B2 (en) 2001-09-13 2016-09-27 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9339383B2 (en) 2001-10-11 2016-05-17 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9132006B2 (en) 2001-10-11 2015-09-15 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9629717B2 (en) 2001-10-11 2017-04-25 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US9320598B2 (en) 2003-03-18 2016-04-26 Edwards Lifesciences Corporation Method of implanting a self-expandable prosthetic heart valve
US9675455B2 (en) 2003-03-18 2017-06-13 Edwards Lifesciences Corporation Method of positioning a minimally-invasive heart valve with cusp positioners
US9724193B2 (en) 2003-03-18 2017-08-08 Edwards Lifesciences Corporation Self-expandable heart valve with stabilizers
US8080054B2 (en) 2003-10-02 2011-12-20 Edwards Lifesciences Corporation Implantable prosthetic valve with non-laminar flow
US9241793B2 (en) 2003-10-02 2016-01-26 Edwards Lifesciences Corporation Method of implanting a prosthetic aortic valve having non-laminar flow
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US9393113B2 (en) 2003-12-23 2016-07-19 Boston Scientific Scimed Inc. Retrievable heart valve anchor and method
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9358110B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9585750B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9320599B2 (en) 2003-12-23 2016-04-26 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8623078B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Replacement valve and anchor
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US9585749B2 (en) 2003-12-23 2017-03-07 Boston Scientific Scimed, Inc. Replacement heart valve assembly
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9308085B2 (en) 2003-12-23 2016-04-12 Boston Scientific Scimed, Inc. Repositionable heart valve and method
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US9532872B2 (en) 2003-12-23 2017-01-03 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US8535373B2 (en) 2004-03-03 2013-09-17 Sorin Group Italia S.R.L. Minimally-invasive cardiac-valve prosthesis
US9775704B2 (en) 2004-04-23 2017-10-03 Medtronic3F Therapeutics, Inc. Implantable valve prosthesis
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US9744035B2 (en) 2004-06-16 2017-08-29 Boston Scientific Scimed, Inc. Everting heart valve
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US7462191B2 (en) 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US9480556B2 (en) 2004-09-07 2016-11-01 Medtronic, Inc. Replacement prosthetic heart valve, system and method of implant
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US8617236B2 (en) 2004-11-05 2013-12-31 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8540768B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US9486313B2 (en) 2005-02-10 2016-11-08 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8920492B2 (en) 2005-02-10 2014-12-30 Sorin Group Italia S.R.L. Cardiac valve prosthesis
US8539662B2 (en) 2005-02-10 2013-09-24 Sorin Group Italia S.R.L. Cardiac-valve prosthesis
US9415225B2 (en) 2005-04-25 2016-08-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US9649495B2 (en) 2005-04-25 2017-05-16 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9504564B2 (en) 2005-05-13 2016-11-29 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US9138312B2 (en) 2006-09-19 2015-09-22 Medtronic Ventor Technologies Ltd. Valve prostheses
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US8348995B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies, Ltd. Axial-force fixation member for valve
US9301834B2 (en) 2006-09-19 2016-04-05 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8771345B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US8348996B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies Ltd. Valve prosthesis implantation techniques
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8414643B2 (en) 2006-09-19 2013-04-09 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8771346B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthetic fixation techniques using sandwiching
US9642704B2 (en) 2006-09-19 2017-05-09 Medtronic Ventor Technologies Ltd. Catheter for implanting a valve prosthesis
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US9387071B2 (en) 2006-09-19 2016-07-12 Medtronic, Inc. Sinus-engaging valve fixation member
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US9114008B2 (en) 2006-12-22 2015-08-25 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method for making the same
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US7871436B2 (en) 2007-02-16 2011-01-18 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9585754B2 (en) 2007-04-20 2017-03-07 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9095433B2 (en) 2007-09-13 2015-08-04 Georg Lutter Truncated cone heart valve stent
US9254192B2 (en) 2007-09-13 2016-02-09 Georg Lutter Truncated cone heart valve stent
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9730792B2 (en) 2007-09-13 2017-08-15 Georg Lutter Truncated cone heart valve stent
US9693859B2 (en) 2007-09-26 2017-07-04 St. Jude Medical, Llc Collapsible prosthetic heart valves
US9636221B2 (en) 2007-09-26 2017-05-02 St. Jude Medical, Inc. Collapsible prosthetic heart valves
US9510942B2 (en) 2007-12-14 2016-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US8157852B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US8685077B2 (en) 2008-01-24 2014-04-01 Medtronics, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8784480B2 (en) 2008-02-29 2014-07-22 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US8460368B2 (en) 2008-02-29 2013-06-11 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8511244B2 (en) 2008-04-23 2013-08-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US9662204B2 (en) 2008-06-06 2017-05-30 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US8454685B2 (en) 2008-06-06 2013-06-04 Edwards Lifesciences Corporation Low profile transcatheter heart valve
US9561101B2 (en) 2008-06-20 2017-02-07 Edwards Lifesciences Corporation Two-part prosthetic valve system
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
US8236049B2 (en) 2008-06-20 2012-08-07 Edwards Lifesciences Corporation Multipiece prosthetic mitral valve and method
US9681949B2 (en) 2008-07-15 2017-06-20 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US9675449B2 (en) 2008-07-15 2017-06-13 St. Jude Medical, Llc Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9364325B2 (en) 2008-08-22 2016-06-14 Edwards Lifesciences Corporation Prosthetic heart valve delivery system and method
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8252051B2 (en) 2009-02-25 2012-08-28 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US8512397B2 (en) 2009-04-27 2013-08-20 Sorin Group Italia S.R.L. Prosthetic vascular conduit
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US9433500B2 (en) 2009-12-04 2016-09-06 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9084676B2 (en) 2009-12-04 2015-07-21 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US8986373B2 (en) 2009-12-04 2015-03-24 Edwards Lifesciences Corporation Method for implanting a prosthetic mitral valve
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8926691B2 (en) 2009-12-04 2015-01-06 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US9717591B2 (en) 2009-12-04 2017-08-01 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US9248017B2 (en) 2010-05-21 2016-02-02 Sorin Group Italia S.R.L. Support device for valve prostheses and corresponding kit
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9393110B2 (en) 2010-10-05 2016-07-19 Edwards Lifesciences Corporation Prosthetic heart valve
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
US8858461B2 (en) 2010-11-19 2014-10-14 Jean-Charles Persat Tissue sampling tool, in particular for adipose tissue
FR2967567A1 (en) * 2010-11-19 2012-05-25 Jean-Charles Persat Levy vector for particular adipose tissue
EP2455115A1 (en) 2010-11-19 2012-05-23 Persat, Jean-Charles Sampling carrier for tissue, in particular adipose
US9161836B2 (en) 2011-02-14 2015-10-20 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9289289B2 (en) 2011-02-14 2016-03-22 Sorin Group Italia S.R.L. Sutureless anchoring device for cardiac valve prostheses
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9370421B2 (en) 2011-12-03 2016-06-21 Boston Scientific Scimed, Inc. Medical device handle
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9757229B2 (en) 2011-12-09 2017-09-12 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9138314B2 (en) 2011-12-29 2015-09-22 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US8685084B2 (en) 2011-12-29 2014-04-01 Sorin Group Italia S.R.L. Prosthetic vascular conduit and assembly method
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9675452B2 (en) 2013-02-12 2017-06-13 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal

Similar Documents

Publication Publication Date Title
EP0624349B1 (en) Device for tamponade in and maintenance of bony body cavities
DE102006027873B4 (en) Endoscopic multifunction surgical unit
EP0479730B1 (en) Balloon dilatation catheter
EP0536440B1 (en) H.F. surgical instrument for cutting and coagulating
EP1281360B1 (en) Surgical instrument for endoscopic use
DE10049812B4 (en) Apparatus for filtering of macroscopic particles from the blood stream to the local removal of an aortic valve on the human or animal heart
DE19924311A1 (en) Clip cutting device to cut body tissue and place staple on at least one side of cut line; has clamp head with staples and pressure plate part, with collagen and fibrin fleece underlay covering staples
EP0117519A1 (en) Catheter
WO2009027065A1 (en) Trocar tube, trocar, obturator, or rectoscope for transluminal endoscopic surgery via natural body cavities
DE10049814A1 (en) Operating framework has anchoring elements attaching it to vessel's inner wall, is coiled or folded into cylindrical, and has connecting or contact structure.
WO1999051283A2 (en) Flexible trocar with an upturning tube system
EP1731105A1 (en) Device for establishing free transcutaneous access to an endoscopic surgical area
EP0421457A1 (en) Device for removal of deposits in vessels
DE19732234A1 (en) Surgical endoscopic instrument
WO2007147439A1 (en) Device for introducing and positioning surgical instruments and corresponding method
DE10010467A1 (en) Balloon catheter comprises an addititional tensioning balloon which is inflatable by means of a fluid supplied through the catheter tube to ensures that the cutting wires are kept at a specified tension
DE19706751A1 (en) An electrosurgical instrument for ablating tissue in body spaces
DE4116648C2 (en)
DE3804849A1 (en) Device for removing blood clots from vessels
DE10049815B4 (en) Device for the local removal of an aortic valve on the human or animal heart
DE19528440C2 (en) A surgical cutting instrument
DE4204210A1 (en) Tissue etc., extraction instrument from stomach cavity
WO2006108480A1 (en) Endoscopic surgical instrument
DE4114204A1 (en) Surgical stitching appliance - has tubular handle and rigid needle of suitable shape for lapariscopsy
EP0499243A1 (en) Extraction retainer for endoscopic surgery

Legal Events

Date Code Title Description
8100 Publication of the examined application without publication of unexamined application
D1 Grant (no unexamined application published) patent law 81
8364 No opposition during term of opposition
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20120501