DE10049812B4 - Apparatus for filtering of macroscopic particles from the blood stream to the local removal of an aortic valve on the human or animal heart - Google Patents

Apparatus for filtering of macroscopic particles from the blood stream to the local removal of an aortic valve on the human or animal heart

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Publication number
DE10049812B4
DE10049812B4 DE2000149812 DE10049812A DE10049812B4 DE 10049812 B4 DE10049812 B4 DE 10049812B4 DE 2000149812 DE2000149812 DE 2000149812 DE 10049812 A DE10049812 A DE 10049812A DE 10049812 B4 DE10049812 B4 DE 10049812B4
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Prior art keywords
filter
characterized
device according
filter screens
clamped
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Expired - Fee Related
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DE2000149812
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German (de)
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DE10049812A1 (en )
Inventor
Rico Bergmann
Ulrich Dr. Matern
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Universitaetsklinikum Freiburg
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Universitaetsklinikum Freiburg
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/018Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0006Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0073Quadric-shaped
    • A61F2230/0076Quadric-shaped ellipsoidal or ovoid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0073Quadric-shaped
    • A61F2230/008Quadric-shaped paraboloidal

Abstract

Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist, dadurch gekennzeichnet, dass zwei Filterschirme vorgesehen sind, die derart in Wirkverbindung stehen, dass im aufgespannten Zustand ihre konkav ausgebildeten Seiten gegenüberliegen. Apparatus for filtering of macroscopic particles from a bloodstream at the local removal of an aortic valve on the human or animal heart with at least one umbrella-like clampable filter screen which is clamped from a collapsed state to a clamped state and operable by means of a working catheter, characterized in that two filter screens provided are standing in operative connection that whilst clamped opposite their concave sides.

Description

  • Die Erfindung bezieht sich auf eine Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist. The invention relates to a device for filtering of macroscopic particles from a bloodstream at the local removal of an aortic valve on the human or animal heart with at least one umbrella-like clampable filter screen which is clamped from a collapsed state to a clamped state and operable by means of a working catheter.
  • Stand der Technik State of the art
  • Bei einer Vielzahl von Patienten kommt es vor, dass sich im Laufe der Zeit Ablagerungen an der Herzklappe bilden, insbesondere an der Aortenklappe, häufig in Form von Kalkablagerungen oder sonstigen Materialdepositionen. In a large number of patients, it happens that over time form deposits on the heart valve, especially the aortic valve, often in the form of calcium deposits or other material deposition. Durch derartige Materialablagerungen an der Aortenklappe, die in einem gesunden Zustand als ein feines flexibles Gewebesegel ausgebildet ist, kommt es zu einer irreversiblen Versteifung der Aortenklappe, wodurch insbesondere der Blutabfluss aus dem Herz erheblich in Mitleidenschaft gezogen wird. By such material deposits on the aortic valve, which is designed as a fine flexible fabric sail in a healthy condition, there is an irreversible stiffening of the aortic valve, whereby in particular the flow of blood is drawn from the heart significantly affected. Blutunterversorgung im gesamten Körper ist die Folge, so dass in einem derart fortgeschrittenen Stadium ein akuter Handlungsbedarf besteht, will man schwerwiegende Folgen für den Patienten vermeiden. Low blood supply throughout the body is the result, so that in such an advanced stage there is an acute need for action, wants to avoid serious consequences for the patient. Bisher bekannte medikamentöse Behandlungsmethoden zeigen jedoch nur begrenzten Erfolg, so dass nach heutiger Kenntnis einer Verkalkung von Aortenklappen lediglich durch einen schwerwiegende chirurgischen Eingriff begegnet werden kann. However, previously known drug treatments show limited success, so that can only be met by a serious surgical procedure now known to calcification of the aortic valve.
  • Üblicherweise wird in diesem Fall im Rahmen einer Sternotomie der Brustkorb eines Menschen geöffnet um Zugang zum Herz und insbesondere zu den verkalkten Aortenklappen zu erhalten, die mit bekannten Schneidewerkzeugen aus dem Körper extrahiert wird. Typically, the chest of a human being is opened to access the heart and in particular to the calcified aortic valve to obtain in this case as part of a sternotomy, which is extracted with known cutting tools from the body. Beispielsweise eignen sich hierzu Extraktionswerkzeuge wie sie in den amerikanischen Druckschriften For example, this extraction tools are in the American publications they US 6,033,419 US 6,033,419 sowie as US 5,827,316 US 5,827,316 beschrieben sind. are described. Nach erfolgtem operativen Eingriff und Wiederverschluss des Brustkorbes steht dem Patienten eine langwierige Heilungsdauer bevor, die in den meisten Fällen mit einer ebenso langwierigen Rehabilitationszeit gefolgt ist. After the surgery and re-closure of the thorax the patient is facing a lengthy healing period that is followed in most cases with an equally lengthy rehabilitation period.
  • Nun sind auch Operationstechniken bekannt geworden, die unter Einsatz von Kathetern und Endoskopen eine Behandlung der Aortenklappe auch mit weit geringeren Belastungen für den Patienten ermöglichen. Now surgical techniques have been disclosed which allow using catheters and endoscopes treatment of the aortic valve with far less stress for the patient. Dies jedoch setzt voraus, dass die verkalkte Aortenklappe mit Hilfe geeigneter Katheterwerkzeuge vor Ort abgetragen wird. This presupposes that the calcified aortic valve is removed with the aid of suitable catheters tools on site. Ein derartiger Abtrag der verkalkten Aortenklappe, unabhängig davon mit welchen Abtragungstechniken gearbeitet wird, führt jedoch nahezu unvermeidbar zu zerkleinerten, abgetragenen, dh abgetrennten und Iosgelösten Gewebebruchstücken, die in die freie Blutbahn gelangen können, sofern sie nicht durch entsprechende Absaugtechniken extrakorporal extrahiert werden können. Such a removal of the calcified aortic valve, working regardless of what removal techniques, but leads almost inevitably to crushed, worn, ie severed and Iosgelösten tissue fragments that can get into the free bloodstream, if they can not be extracted outside the body by appropriate suction techniques. Derartige, sich in der Blutbahn befindliche Bruchstücke mit makroskopischen Teilchendurchmessern von > 7,5 μm erhöhen jedoch drastisch die Thrombose- und Emboliegefahr des Patienten, so dass nach Maßnahmen gesucht wird, eben jene, bei der Extraktion der verkalkten Aortenklappe möglicherweise entstehenden Abbruchstücke vollständig aus der Blutbahn zu entfernen. However, increase such, be present in the bloodstream fragments with macroscopic particle diameters of> 7.5 microns dramatically thrombosis and embolism risk of the patient, so that searched for measures just those that may arise in the extraction of calcified aortic valve demolition pieces completely from the remove bloodstream.
  • Aus der From the DE 298 80 158 U1 DE 298 80 158 U1 geht ein Embolieschutzgerät in Art eines intravenös einbringbaren Faltschirmes hervor, der als eine Art Filter in der Blutbahn innerhalb eines Blutgefäßes aufgespannt werden kann, um auf diese Weise die Emboliegefahr erhöhende Partikel aus der Blutbahn auszufiltern. shows an embolic protection device in the manner of a intravenously insertable Faltschirmes which can be clamped as a filter in the blood stream within a blood vessel to filter out in this way the risk of embolism enhancing particles from the bloodstream.
  • Darstellung der Erfindung Summary of the Invention
  • Der Erfindung liegt die Aufgabe zugrunde, eine Vorrichtung zum Ausfiltern bzw. Auffangen makroskopischer Teilchen aus einer Blutbahn für den lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist, derart weiterzubilden, dass während des chirurgischen Eingriffes zum Abtrag der Aortenklappe entstehende makroskopisch große Teilchen, die nicht entsprechend entsorgt werden und in die Blutbahn gelangen, vollständig aufgefangen werden sollen. The object of the invention is to provide a device for filtering and collecting the macroscopic particles from a bloodstream for the local removal of an aortic valve on the human or animal heart with at least one umbrella-like clampable filter screen which is clamped from a collapsed state to a clamped state, and means a working catheter is operable to further develop such a way that formed during the surgical procedure for the removal of the aortic valve macroscopically large particles which are not disposed of and pass into the bloodstream, should be completely absorbed. Es soll insbesondere erreicht werden, dass der chirurgische Eingriff zur Ablation der Aortenklappe sicherer durchführbar ist. It is to be achieved in particular that the surgery for ablation of the aortic valve is safer to perform. Insbesondere soll die Vorrichtung auch einen minimal invasiven Eingriff zur Ablation der Aortenklappe nicht hinderlich im Wege stehen, sondern überdies den Eingriff erleichtern. In particular, the device should not be even a minimally invasive procedure for ablation of the aortic valve in the way of an obstacle, but also facilitate the engagement.
  • Die Lösung der Aufgabe ist im Anspruch 1 angegeben. The solution of the problem is defined in claim. 1 Vorteilhafte Weiterbildungen des Erfindungsgedankens sind Gegenstand der Unteransprüche sowie dem Beschreibungstext unter Bezugnahme auf das Ausführungsbeispiel zu entnehmen. Advantageous further developments of the invention are the subject matter of the subclaims and the description text with reference to the embodiment can be seen.
  • Erfindungsgemäß ist eine Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe, insbesondere am menschlichen Herz, gemäß dem Oberbegriff des Anspruchs 1 derart ausgebildet, dass zwei Filterschirme vorgesehen sind, die derart in Wirkverbindung stehen, dass im aufgespannten Zustand ihre konkav ausgebildeten Filterschirmseiten gegenüberliegen. According to the invention an apparatus for filtering macroscopic particles from a bloodstream at the local removal of an aortic valve, especially on the human heart, in accordance with the preamble of claim 1 configured such that two filter screens are provided which are in operative connection, that in the clamped state their concaved The filter screen of sides opposite each other.
  • Der Erfindung liegt die Idee zugrunde, dass durch die Kombination zweier Filterschirme, deren Konkavseiten sich gegenüberliegen, ein Volumen einbeschrieben wird, das in Art eines Käfigs von den Filterschirmen umgeben wird und in dem die chirurgischen Maßnahmen an der Aortenklappe durchgeführt werden kann. The invention is based on the idea that by combining two filter screens, their concave sides opposite to each other, a volume is inscribed, which is in the manner of a cage surrounded by the filter screens and in which the surgical procedure on the aortic valve can be performed. Hierzu ist es erforderlich, dass ein Filterschirm vor und der andere Filterschirm hinter der Aortenklappe angeordnet wird. For this purpose, it is necessary that a filter screen in front and the other filter screen is arranged behind the aortic valve. Nach entsprechendem Aufspannen der Filterschirme kann innerhalb des durch die Filterschirme einbeschriebenen Volumens die Ablation der Aortenklappe vorgenommen werden. After appropriate clamping of the filter screens ablation of the aortic valve can be made within the inscribed by the filter screens volume. Während der Ablation entstehende makroskopische Bruchstücke werden von den Filterschirmflächen aufgefangen und daran gehindert, in die übrige Blutbahn zu gelangen. During ablation, resulting macroscopic fragments are caught by the filter screen areas and prevented from entering the rest of the bloodstream. Nach Vollendung der Ablation und sonstiger chirurgischer Maßnahmen werden die Filterschirme zusammengefaltet und die darin gefangenen makroskopischen Teilchen wie auch evtl. die als Ganzes entfente Aortenklappe eingeschlossen. Upon completion of the ablation and other surgical procedures, the filter screens are folded and trapped inside macroscopic particles as well as possibly the enclosed as a whole entfente aortic valve. Die Dimensionierung der Filterschirmchen ist dabei derart gewählt, dass sie durch übliche Arbeitshohlkatheter geschoben werden können, so dass nach Beendigung der chirurgischen Maßnahme die mit makroskopischen Teilchen gefüllten Filterschirmchen durch einen entsprechenden Arbeitskanal extrakorporal verbracht werden können. The dimensioning of the Filterschirmchen is chosen such that they can be pushed by the usual work hollow catheter so that after completion of the surgical procedure, the Filterschirmchen filled with macroscopic particles can be introduced extracorporeally through a corresponding working channel.
  • Das Filtermaterial, aus dem die einzelnen Filterschirme bestehen, ist derart gewählt, dass die natürlichen Blutbestandteile ungehindert durch das Filtermaterial hindurchtreten können. The filter material of which the individual filter screens are made, is selected such that the natural blood components can pass through the filter material unhindered. Makroskopische Teilchen mit Teilchengrößen von mehr als 7,5 μm bleiben jedoch im Filtermaterial hängen und können entsprechend entsorgt werden. However, macroscopic particles with particle sizes greater than 7.5 microns are caught in the filter material and can be disposed of.
  • Kurze Beschreibung der Erfindung Summary of the Invention
  • Die Erfindung wird nachstehend ohne Beschränkung des allgemeinen Erfindungsgedankens anhand von Ausführungsbeispielen unter Bezugnahme auf die Zeichnung exemplarisch beschrieben. The invention is described below, without limiting the general inventive idea with reference to embodiments with reference to the accompanying drawing. Es zeigen: Show it:
  • 1a,b 1a, b schematisierte Darstellung der Filterschirmanordnung im zusammengefalteten sowie entspannten Zustand, sowie schematic representation of the filter screen assembly in the folded and relaxed state, and
  • 2 2 Filterschirmanordnung innnerhalb eines Blutgefäßes. Filter screen assembly made within a blood vessel.
  • Wege zur Ausführung der Erfindung, gewerbliche Verwendbarkeit WAYS OF IMPLEMENTING THE INVENTION, INDUSTRIAL APPLICABILITY
  • In In 1a 1a sind schematisiert zwei alternative Filterschirmanordnungen in zusammengefaltetem Zustand dargestellt. Two alternative filter screen arrangements are shown in collapsed condition schematically. Entlang einer Verbindungsachse Along a connection axis 1 1 , die mit einem Arbeitskatheter , With a working catheter 2 2 verbunden ist, sind zwei zusammengefaltete Filterschirme is connected, two collapsed filter screens 3 3 und and 4 4 angeordnet. arranged. Die Filterschirme The filter screens 3 3 , . 4 4 liegen im zusammengefalteten Zustand eng an der Verbindungsachse are in the folded state close to the connection axis 1 1 an, so dass sie durch einen dünnen Arbeitshohlkanal , so that they work by a thin hollow channel 7 7 eines Katheters geschoben werden können. a catheter can be pushed. Mittig zur Filterschirmfläche sind beide Filterschirme Centrally to the filter screen surface are both filter screens 3 3 und and 4 4 mit der Verbindungsachse with the connecting axis 1 1 fest verbunden, so dass sie im aufgespannten Zustand gemäß fixedly connected so that it in the clamped state according to 1b 1b mit ihren konkaven Seiten spiegelsymmetrisch relativ zu einer senkrecht zur Verbindungsachse ausgebildet sind. are formed with their concave sides mirror-symmetrically relative to a plane perpendicular to the connection axis.
  • Alternativ zur der in As an alternative to the in 1a 1a oben dargestellten zweigeteilten Ausführungsform der Filterschirme shown above, two divided screens embodiment, the filter 3 3 und and 4 4 ist es auch möglich durch enstrprechende Wahl des Filterschirmmaterials die Filterschirme it is also possible by enstrprechende choice of filter screen material, the filter screens 3 3 und and 4 4 an ihren Randbereichen zusammenzufügen, so dass sie im zusammengefalteten Zustand lediglich einen geschlossenen zusammenhängenden Schlauch darstellen, der auch ohne die Verwendung eines Arbeitshohlkanals put together at their edge regions, so that they represent only a closed tube connected in the folded state even without the use of a work hollow channel 2 2 in das Gefäß eingeführt werden kann. can be introduced into the vessel. Hierbei ist insbesondere darauf zu achten, dass das disale Ende der zusammengefalteten Filterschirmanordnung über eine Abrundung Here is particularly important to ensure that the disale end of the folded filter screen assembly via a rounding 8 8th verfügt, so dass die Gefäßwand während des Einführvorganges nicht beschädigt wird. has, so that the vessel wall is not damaged during the insertion.
  • Zum Aufspannen der beiden Filterschirme ist jeweils ein Schlittenelement To clamp the two filter screens, a respective slide element 5 5 vorgesehen, das längs der Verbindungsachse provided, along the connection axis 1 1 beweglich angeordnet ist. is movably disposed. Mit dem Schlittenelement With the carriage element 5 5 sind Spreizstreben are expanding struts 6 6 verbunden, die am Randbereich der Filterschirme angelenkt sind. connected, are hinged on the edge region of the filter screens. Durch entsprechendes Verschieben der Schlittenelemente By appropriate shifting of the carriage elements 5 5 in Richtung der Fixierstellen, an denen das Filtermaterial fest an der Verbindungsachse in the direction of the fixing points at which the filter material is fixed on the connecting shaft 1 1 angebracht ist, entfalten sich die Spreizstreben is attached, the expansion braces unfold 6 6 , wodurch die Filterschirme radial zur Verbindungsachse Whereby the filter screens radially to the connection axis 1 1 gespreizt werden. be spread.
  • Im gespannten Zustand der Filterschirmanordnung umschließen beide Filterschirme In the stressed state of the filter screen assembly both filter screens enclose 3 3 und and 4 4 ein inneres Volumen, in dem die Ablation der Aortenklappe vorgenommen werden kann. an inner volume in which ablation of the aortic valve can be made. Selbstverständlich ist es möglich, beide Randbereiche der Filterschirme derart miteinander zu verbinden, so dass das innere Volumen vollständig umschlossen ist. It is of course possible to connect both edge portions of the filter screens in such a manner so that the internal volume is completely enclosed. Entsprechende Öffnungen innerhalb des Filtermaterials sind vorzusehen, um die für die Ablation erforderlichen Werkzeugkatheter einzuführen. Corresponding openings within the filter material to be provided in order to introduce the required tool for the ablation catheter. Diese können jedoch auch längs zur Verbindungsachse However, this can also along the connecting axis 1 1 in das Innere der aufgespannten Filterschirme hineinreichen. extend into the interior of the clamped filter screens.
  • Zur Durchführung der Ablation einer verkalkten Aortenklappe wird die Filterschirmanordnung im zusammengefalteten Zustand durch eine, in der Aortenklappe vorhandene Öffnung hindurchgeschoben, so dass ein Filterschirm To carry out the ablation of a calcified aortic valve, the filter screen assembly in the folded state is pushed through one of the aortic valve in existing opening, so that a filter screen 3 3 auf der einen Seite der Aortenklappe zu liegen kommt und der andere Filterschirm to lie on one side of the aortic valve is and the other filter screen 4 4 auf der gegenüberliegenden Seite. on the opposite side. Im aufgeklappten Zustand vermögen die Filterschirme die zu ablatierende Aortenklappe vollständig zu umschließen. In the unfolded state, the filter screens are able to completely enclose the to be ablated aortic valve. Da das Filtermaterial für die natürlichen Blutbestandteile durchlässig ist, können die chirurgischen Maßnahmen trotz andauernder Herztätigkeit unternommen werden. Since the filter material for the natural blood components is permeable, the surgical measures can be undertaken despite ongoing cardiac activity.
  • Nach entsprechender Positionierung und Zentrierung der Filterschirmanordnung innerhalb des Aortenbogens respektive nach Justierung relativ zur ablatierenden Aortenklappe zentriert sich die Filterschirmanordnung selbständig durch Aufspreizen der einzelnen Filterschirme an der Innenwandung der Aorta. After appropriate positioning and centering the filter screen assembly within the aortic arch, respectively, relative to adjustment to be ablated aortic valve, the filter screen assembly is centered automatically by spreading apart of the individual filter screens on the inner wall of the aorta. Die Filterschirmanordnung dient in diesem Fall auch zugleich als mechanischer Fixpunkt bzw. Auflagemöglichkeit für die für die Ablation einzusetzenden mikrochirurgischen Instrumente. The filter screen assembly in this case serves at the same time as a mechanical fixture or support option for employed for ablation microsurgical instruments. Auf diese Weise ist eine Mikronavigation der für die Ablation erforderlichen Katheterwerkzeuge erheblich vereinfacht im Vergleich zu bisherigen Techniken, bei denen eine derartige Justierhilfe nicht vorhanden ist. In this way, a micro navigation required for the ablation catheter tools is greatly simplified compared to previous techniques in which such an adjustment aid does not exist.
  • In In 2 2 ist nochmals die Filterschirmanordnung innerhalb des Aortenbogens in zwei Stellungen is again the filter screen assembly within the aortic arch in two positions 1 1 und and 2 2 gezeigt. shown. In Stellung In position 1 1 ist die stark schematisiert dargestellte Filterschirmanordnung im zusammengefalteten Zustand dargestellt und wird in dieser Weise durch das Innere der Aorta geschoben. the filter screen assembly shown highly schematically represented in the folded state and is slid in this manner through the interior of the aorta. Die Filterschirmanordnung ist proximal mit einem elastischen Arbeitskatheter verbunden, der zugleich auch für die Navigation der Filterschirmanordnung innerhalb der Aorta sorgt. The filter screen assembly is proximally connected to an elastic working catheter, at the same time also provides for the navigation of the filter screen assembly within the aorta. Besonders vorteilhaft ist die distalseits abgerundete Form der Filterschirmanordnung im zusammengefalteten Zustand, die dafür sorgt, dass keine traumatischen Gewebeirritationen während des Einbringvorgangs der Filterschirmanordnung in den Körper entstehen. Particularly advantageous is the distalseits rounded shape of the filter screen assembly in the folded state, which ensures that no traumatic tissue irritation occur in the body during Einbringvorgangs the filter screen assembly. In der Position In the position 2 2 gemäß according to 2 2 ist die Filterschirmanordnung im aufgespannten Zustand dargestellt und es wird deutlich, dass die Filterschirmrandbereiche an die Innenwandung der Aorta anstoßen. the filter screen assembly is shown in the clamped state, and it is clear that the filter screen edge portions abut against the inner wall of the aorta. Hierdurch ist gewährleistet, dass eine Selbstzentrierung der Filterschirmanordnung erfolgt. This ensures that a self-centering of the filter screen assembly takes place.
  • Neben dem in In addition to the in 1 1 dargestellten Ausführungsbeispiel sind auch andere Lösungen zum Aufspannen der Filterschirme denkbar, wie beispielsweise ein Aufspannmechanismus der durch Rotation der Filterschirmanordnung um die Längsachse des Arbeitskatheters erfolgt. Embodiment shown, also other solutions for clamping the filter screens conceivable, such as a chuck mechanism takes place about the longitudinal axis of the working catheter by rotation of the filter screen assembly. Ebenso kann der Arbeitskatheter gemäß Similarly, the working catheter, according 2 2 auch als Durchführkanal für die für die Ablation erforderlichen Katheterwerkzeuge dienen, so dass diese unmittelbar nach Austritt aus dem Arbeitskatheter in das Innenvolumen der aufgespannten Filterschirme gelangen. also serve as a lead-through channel for the required for the ablation catheter tools so that they pass directly after leaving the working catheter in the internal volume of the clamped filter screens.
  • 1 1
    Verbindungsachse connecting axis
    2 2
    Arbeitskatheter working catheter
    3, 4 3, 4
    Filterschirm filter screen
    5 5
    Schlittenelement carriage element
    6 6
    Spreizstreben expansion braces

Claims (9)

  1. Vorrichtung zum Ausfiltern makroskopischer Teilchen aus einer Blutbahn beim lokalen Abtrag einer Aortenklappe am menschlichen oder tierischen Herz mit wenigstens einem schirmartig aufspannbaren Filterschirm, der aus einem zusammengefalteten Zustand in einen aufgespannten Zustand aufspannbar ist und mittels eines Arbeitskatheters betätigbar ist, dadurch gekennzeichnet , dass zwei Filterschirme vorgesehen sind, die derart in Wirkverbindung stehen, dass im aufgespannten Zustand ihre konkav ausgebildeten Seiten gegenüberliegen. Apparatus for filtering of macroscopic particles from a bloodstream at the local removal of an aortic valve on the human or animal heart with at least one umbrella-like clampable filter screen which is clamped from a collapsed state to a clamped state and operable by means of a working catheter, characterized in that two filter screens provided are standing in operative connection that whilst clamped opposite their concave sides.
  2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, dass die Filterschirme auf einer gemeinsamen Verbindungsachse angebracht sind, entlang der die Filterschirme im zusammengefalteten Zustand anliegen und von der sich die Filterschirme radial im aufgespannten Zustand erstrecken. Device according to claim 1, characterized in that the filter screens are mounted on a common connection axis along which the filter screens abut in the folded state and from which the filter screens extend radially in the clamped.
  3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, dass die Filterschirme bezogen auf eine die Verbindungsachse senkrecht schneidenden Achse spiegelsymmetrisch ausgebildet sind. Device according to claim 2, characterized in that the filter screens to the connection axis perpendicularly intersecting the axis are mirror symmetrical with respect.
  4. Vorrichtung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass die Filterschirme aus einem Filtermaterial bestehen, durch das die natürlichen Blutbestandteile ungehindert hindurchtreten aber makroskopische Teilchen mit Teilchengrößen von 7,5 um und mehr das Filtermaterial nicht passieren. Device according to one of claims 1 to 3, characterized in that the filter screens are made of a filter material through which pass unhindered but the natural blood components macroscopic particles having particle sizes of 7.5 microns and more not pass through the filter material.
  5. Vorrichtung nach einem der Ansprüche 2 bis 4, dadurch gekennzeichnet, dass die Filterschirme mittig zu ihrer Filterschirmfläche an der Verbindungsachse befestigt sind und mit jeweils einem Schlittenelement, das längs zur Verbindungsachse beweglich ist, über Spreizstreben, die jeweils mit dem Randbereich der Filterschirmfläche, verbunden sind. Device according to one of claims 2 to 4, characterized in that the filter screens are mounted centrally with respect to their filter screen surface to the connection axis and each having a slide member which is movable along the connecting axis, over expansion braces, which are each connected to the edge region of the filter screen surface, ,
  6. Vorrichtung nach Anspruch 5, dadurch gekennzeichnet, dass der Arbeitskatheter mit den Schlittenelementen in Wirkverbindung steht. Device according to claim 5, characterized in that the working catheter is in operative connection with the slide elements.
  7. Vorrichtung nach einem der Ansprüche 1 bis 6, dadurch gekennzeichnet, dass die Filterschirme im aufgespannten Zustand ein nahezu vollständig umschlossenes Volumen mit den Filterschirmen einschließen. Device according to one of claims 1 to 6, characterized in that the filter screens whilst clamped include an almost completely enclosed volume with the filter screens.
  8. Vorrichtung nach einem der Ansprüche 1 bis 7, dadurch gekennzeichnet, dass die Filterschirme im aufgespannten Zustand einen Filterschirmdurchmesser von bis zu 2,9 cm aufweisen und im zusammengefalteten Zustand längs durch einen Hohlkatheter mit einem Arbeitskanaldurchmesser von maximal 1 cm Durchmesser schiebbar sind. Device according to one of claims 1 to 7, characterized in that the filter screens in the clamped state have a filter screen diameter of up to 2.9 cm, and in the folded state can be pushed lengthwise through a hollow catheter having a working channel diameter of a maximum of 1 cm in diameter.
  9. Vorrichtung nach einem der Ansprüche 1 bis 8, dadurch gekennzeichnet, dass die Filterschirme mit ihren Randbereichen der Filterschirmfläche peripher verbunden sind. Device according to one of claims 1 to 8, characterized in that the filter screens are connected peripherally with their edge regions of the filter screen surface.
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Cited By (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009076482A1 (en) * 2007-12-10 2009-06-18 Incept, Llc Retrieval apparatus and methods for use
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US7846203B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Implanting a stent valve prosthesis at the native aortic valve
US7871436B2 (en) 2007-02-16 2011-01-18 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US8080054B2 (en) 2003-10-02 2011-12-20 Edwards Lifesciences Corporation Implantable prosthetic valve with non-laminar flow
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US8236049B2 (en) 2008-06-20 2012-08-07 Edwards Lifesciences Corporation Multipiece prosthetic mitral valve and method
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252051B2 (en) 2009-02-25 2012-08-28 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8460368B2 (en) 2008-02-29 2013-06-11 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
US8518073B2 (en) 2009-01-29 2013-08-27 Claret Medical, Inc. Illuminated intravascular blood filter
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US8753370B2 (en) 2009-07-27 2014-06-17 Claret Medical, Inc. Dual endovascular filter and methods of use
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US8876796B2 (en) 2010-12-30 2014-11-04 Claret Medical, Inc. Method of accessing the left common carotid artery
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US9114008B2 (en) 2006-12-22 2015-08-25 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method for making the same
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9132006B2 (en) 2001-10-11 2015-09-15 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US9241788B2 (en) 2001-03-23 2016-01-26 Edwards Lifesciences Corporation Method for treating an aortic valve
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US9326843B2 (en) 2009-01-16 2016-05-03 Claret Medical, Inc. Intravascular blood filters and methods of use
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9510942B2 (en) 2007-12-14 2016-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9566144B2 (en) 2015-04-22 2017-02-14 Claret Medical, Inc. Vascular filters, deflectors, and methods
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
US10022220B2 (en) 2000-04-06 2018-07-17 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399315B2 (en) 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US7462191B2 (en) 2004-06-30 2008-12-09 Edwards Lifesciences Pvt, Inc. Device and method for assisting in the implantation of a prosthetic valve
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US7780723B2 (en) 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
JP5628673B2 (en) 2007-09-26 2014-11-19 セント ジュード メディカル インコーポレイテッド Foldable artificial heart valve
US9532868B2 (en) 2007-09-28 2017-01-03 St. Jude Medical, Inc. Collapsible-expandable prosthetic heart valves with structures for clamping native tissue
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
ES2584315T3 (en) 2008-07-15 2016-09-27 St. Jude Medical, Inc. Collapsible designs and reexpansible Prosthetic heart valve sleeve and complementary technological applications
EP2480165B1 (en) 2009-09-21 2017-08-23 Claret Medical, Inc. Intravascular blood filters
US8372108B2 (en) 2009-01-16 2013-02-12 Claret Medical, Inc. Intravascular blood filter
EP2628465A1 (en) 2009-04-27 2013-08-21 Sorin Group Italia S.r.l. Prosthetic vascular conduit
EP2611388A2 (en) 2010-09-01 2013-07-10 Medtronic Vascular Galway Limited Prosthetic valve support structure
US8568475B2 (en) 2010-10-05 2013-10-29 Edwards Lifesciences Corporation Spiraled commissure attachment for prosthetic valve
CA2813419A1 (en) 2010-10-05 2012-04-12 Edwards Lifesciences Corporation Prosthetic heart valve
ES2641902T3 (en) 2011-02-14 2017-11-14 Sorin Group Italia S.R.L. Anchoring device for sutureless heart valve prostheses
EP2486894A1 (en) 2011-02-14 2012-08-15 Sorin Biomedica Cardio S.r.l. Sutureless anchoring device for cardiac valve prostheses
US8795357B2 (en) 2011-07-15 2014-08-05 Edwards Lifesciences Corporation Perivalvular sealing for transcatheter heart valve
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
EP2842517A1 (en) 2011-12-29 2015-03-04 Sorin Group Italia S.r.l. A kit for implanting prosthetic vascular conduits
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
WO2014021905A1 (en) 2012-07-30 2014-02-06 Tendyne Holdings, Inc. Improved delivery systems and methods for transcatheter prosthetic valves
EP2922592A4 (en) 2012-11-21 2016-10-19 Edwards Lifesciences Corp Retaining mechanisms for prosthetic heart valves
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
CN107334563A (en) 2013-05-20 2017-11-10 爱德华兹生命科学公司 Prosthetic heart valve delivery apparatus
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
US10098734B2 (en) 2013-12-05 2018-10-16 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998023976A2 (en) * 1996-11-14 1998-06-04 Schnurer John H Improved apparatus and method for gravitational modification
DE29880158U1 (en) * 1997-11-07 2000-11-30 Salviac Ltd Embolic protection device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998023976A2 (en) * 1996-11-14 1998-06-04 Schnurer John H Improved apparatus and method for gravitational modification
DE29880158U1 (en) * 1997-11-07 2000-11-30 Salviac Ltd Embolic protection device

Cited By (178)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7846203B2 (en) 1996-12-31 2010-12-07 Edwards Lifesciences Pvt, Inc. Implanting a stent valve prosthesis at the native aortic valve
US9486312B2 (en) 1996-12-31 2016-11-08 Edwards Lifesciences Pvt, Inc. Method of manufacturing a prosthetic valve
US9095432B2 (en) 1996-12-31 2015-08-04 Edwards Lifesciences Pvt, Inc. Collapsible prosthetic valve having an internal cover
US8721708B2 (en) 1999-11-17 2014-05-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9066799B2 (en) 1999-11-17 2015-06-30 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7892281B2 (en) 1999-11-17 2011-02-22 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8603159B2 (en) 1999-11-17 2013-12-10 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8876896B2 (en) 1999-11-17 2014-11-04 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US9060856B2 (en) 1999-11-17 2015-06-23 Medtronic Corevalve Llc Transcatheter heart valves
US8801779B2 (en) 1999-11-17 2014-08-12 Medtronic Corevalve, Llc Prosthetic valve for transluminal delivery
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8986329B2 (en) 1999-11-17 2015-03-24 Medtronic Corevalve Llc Methods for transluminal delivery of prosthetic valves
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8998979B2 (en) 1999-11-17 2015-04-07 Medtronic Corevalve Llc Transcatheter heart valves
USRE45865E1 (en) 1999-11-17 2016-01-26 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US10022220B2 (en) 2000-04-06 2018-07-17 Edwards Lifesciences Corporation Methods of implanting minimally-invasive prosthetic heart valves
US8092487B2 (en) 2000-06-30 2012-01-10 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8777980B2 (en) 2000-06-30 2014-07-15 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US7758606B2 (en) 2000-06-30 2010-07-20 Medtronic, Inc. Intravascular filter with debris entrapment mechanism
US8951280B2 (en) 2000-11-09 2015-02-10 Medtronic, Inc. Cardiac valve procedure methods and devices
US9241788B2 (en) 2001-03-23 2016-01-26 Edwards Lifesciences Corporation Method for treating an aortic valve
US7780726B2 (en) 2001-07-04 2010-08-24 Medtronic, Inc. Assembly for placing a prosthetic valve in a duct in the body
US8628570B2 (en) 2001-07-04 2014-01-14 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US9149357B2 (en) 2001-07-04 2015-10-06 Medtronic CV Luxembourg S.a.r.l. Heart valve assemblies
US8002826B2 (en) 2001-07-04 2011-08-23 Medtronic Corevalve Llc Assembly for placing a prosthetic valve in a duct in the body
US9539088B2 (en) 2001-09-07 2017-01-10 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US9572663B2 (en) 2001-09-13 2017-02-21 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9168136B2 (en) 2001-09-13 2015-10-27 Edwards Lifesciences Corporation Methods for deploying self-expanding heart valves
US9452046B2 (en) 2001-09-13 2016-09-27 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US9132006B2 (en) 2001-10-11 2015-09-15 Edwards Lifesciences Pvt, Inc. Prosthetic heart valve and method
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
US8858619B2 (en) 2002-04-23 2014-10-14 Medtronic, Inc. System and method for implanting a replacement valve
US8080054B2 (en) 2003-10-02 2011-12-20 Edwards Lifesciences Corporation Implantable prosthetic valve with non-laminar flow
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US8894703B2 (en) 2003-12-23 2014-11-25 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8623078B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Replacement valve and anchor
US8858620B2 (en) 2003-12-23 2014-10-14 Sadra Medical Inc. Methods and apparatus for endovascularly replacing a heart valve
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9532872B2 (en) 2003-12-23 2017-01-03 Boston Scientific Scimed, Inc. Systems and methods for delivering a medical implant
US8246678B2 (en) 2003-12-23 2012-08-21 Sadra Medicl, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8252052B2 (en) 2003-12-23 2012-08-28 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US9011521B2 (en) 2003-12-23 2015-04-21 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8623076B2 (en) 2003-12-23 2014-01-07 Sadra Medical, Inc. Low profile heart valve and delivery system
US8840662B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve and method
US9393113B2 (en) 2003-12-23 2016-07-19 Boston Scientific Scimed Inc. Retrievable heart valve anchor and method
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US9277991B2 (en) 2003-12-23 2016-03-08 Boston Scientific Scimed, Inc. Low profile heart valve and delivery system
US9358106B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed Inc. Methods and apparatus for performing valvuloplasty
US9308085B2 (en) 2003-12-23 2016-04-12 Boston Scientific Scimed, Inc. Repositionable heart valve and method
US9358110B2 (en) 2003-12-23 2016-06-07 Boston Scientific Scimed, Inc. Medical devices and delivery systems for delivering medical devices
US8231670B2 (en) 2003-12-23 2012-07-31 Sadra Medical, Inc. Repositionable heart valve and method
US9320599B2 (en) 2003-12-23 2016-04-26 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8668733B2 (en) 2004-06-16 2014-03-11 Sadra Medical, Inc. Everting heart valve
US8992608B2 (en) 2004-06-16 2015-03-31 Sadra Medical, Inc. Everting heart valve
US8591570B2 (en) 2004-09-07 2013-11-26 Medtronic, Inc. Prosthetic heart valve for replacing previously implanted heart valve
US9480556B2 (en) 2004-09-07 2016-11-01 Medtronic, Inc. Replacement prosthetic heart valve, system and method of implant
US8328868B2 (en) 2004-11-05 2012-12-11 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US8617236B2 (en) 2004-11-05 2013-12-31 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US9498329B2 (en) 2004-11-19 2016-11-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US9504564B2 (en) 2005-05-13 2016-11-29 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US9060857B2 (en) 2005-05-13 2015-06-23 Medtronic Corevalve Llc Heart valve prosthesis and methods of manufacture and use
US8506620B2 (en) 2005-09-26 2013-08-13 Medtronic, Inc. Prosthetic cardiac and venous valves
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US10058421B2 (en) 2006-03-28 2018-08-28 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US9331328B2 (en) 2006-03-28 2016-05-03 Medtronic, Inc. Prosthetic cardiac valve from pericardium material and methods of making same
US8348995B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies, Ltd. Axial-force fixation member for valve
US8771345B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US9301834B2 (en) 2006-09-19 2016-04-05 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8747460B2 (en) 2006-09-19 2014-06-10 Medtronic Ventor Technologies Ltd. Methods for implanting a valve prothesis
US9642704B2 (en) 2006-09-19 2017-05-09 Medtronic Ventor Technologies Ltd. Catheter for implanting a valve prosthesis
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US8771346B2 (en) 2006-09-19 2014-07-08 Medtronic Ventor Technologies Ltd. Valve prosthetic fixation techniques using sandwiching
US9387071B2 (en) 2006-09-19 2016-07-12 Medtronic, Inc. Sinus-engaging valve fixation member
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US9138312B2 (en) 2006-09-19 2015-09-22 Medtronic Ventor Technologies Ltd. Valve prostheses
US10004601B2 (en) 2006-09-19 2018-06-26 Medtronic Ventor Technologies Ltd. Valve prosthesis fixation techniques using sandwiching
US8414643B2 (en) 2006-09-19 2013-04-09 Medtronic Ventor Technologies Ltd. Sinus-engaging valve fixation member
US8348996B2 (en) 2006-09-19 2013-01-08 Medtronic Ventor Technologies Ltd. Valve prosthesis implantation techniques
US8052750B2 (en) 2006-09-19 2011-11-08 Medtronic Ventor Technologies Ltd Valve prosthesis fixation techniques using sandwiching
US8784478B2 (en) 2006-10-16 2014-07-22 Medtronic Corevalve, Inc. Transapical delivery system with ventruculo-arterial overlfow bypass
US8747459B2 (en) 2006-12-06 2014-06-10 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US9295550B2 (en) 2006-12-06 2016-03-29 Medtronic CV Luxembourg S.a.r.l. Methods for delivering a self-expanding valve
US9114008B2 (en) 2006-12-22 2015-08-25 Edwards Lifesciences Corporation Implantable prosthetic valve assembly and method for making the same
US7871436B2 (en) 2007-02-16 2011-01-18 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9504568B2 (en) 2007-02-16 2016-11-29 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US9237886B2 (en) 2007-04-20 2016-01-19 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9585754B2 (en) 2007-04-20 2017-03-07 Medtronic, Inc. Implant for treatment of a heart valve, in particular a mitral valve, material including such an implant, and material for insertion thereof
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9095433B2 (en) 2007-09-13 2015-08-04 Georg Lutter Truncated cone heart valve stent
US9254192B2 (en) 2007-09-13 2016-02-09 Georg Lutter Truncated cone heart valve stent
WO2009076482A1 (en) * 2007-12-10 2009-06-18 Incept, Llc Retrieval apparatus and methods for use
US9510942B2 (en) 2007-12-14 2016-12-06 Edwards Lifesciences Corporation Leaflet attachment frame for a prosthetic valve
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9089422B2 (en) 2008-01-24 2015-07-28 Medtronic, Inc. Markers for prosthetic heart valves
US8673000B2 (en) 2008-01-24 2014-03-18 Medtronic, Inc. Stents for prosthetic heart valves
US7972378B2 (en) 2008-01-24 2011-07-05 Medtronic, Inc. Stents for prosthetic heart valves
US10016274B2 (en) 2008-01-24 2018-07-10 Medtronic, Inc. Stent for prosthetic heart valves
US9333100B2 (en) 2008-01-24 2016-05-10 Medtronic, Inc. Stents for prosthetic heart valves
US9339382B2 (en) 2008-01-24 2016-05-17 Medtronic, Inc. Stents for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US8157852B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8628566B2 (en) 2008-01-24 2014-01-14 Medtronic, Inc. Stents for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8685077B2 (en) 2008-01-24 2014-04-01 Medtronics, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US8613765B2 (en) 2008-02-28 2013-12-24 Medtronic, Inc. Prosthetic heart valve systems
US8961593B2 (en) 2008-02-28 2015-02-24 Medtronic, Inc. Prosthetic heart valve systems
US9241792B2 (en) 2008-02-29 2016-01-26 Edwards Lifesciences Corporation Two-step heart valve implantation
US8784480B2 (en) 2008-02-29 2014-07-22 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US8460368B2 (en) 2008-02-29 2013-06-11 Edwards Lifesciences Corporation Expandable member for deploying a prosthetic device
US9592120B2 (en) 2008-03-18 2017-03-14 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8511244B2 (en) 2008-04-23 2013-08-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US9061119B2 (en) 2008-05-09 2015-06-23 Edwards Lifesciences Corporation Low profile delivery system for transcatheter heart valve
US7993394B2 (en) 2008-06-06 2011-08-09 Ilia Hariton Low profile transcatheter heart valve
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
US8236049B2 (en) 2008-06-20 2012-08-07 Edwards Lifesciences Corporation Multipiece prosthetic mitral valve and method
US9561101B2 (en) 2008-06-20 2017-02-07 Edwards Lifesciences Corporation Two-part prosthetic valve system
US9364325B2 (en) 2008-08-22 2016-06-14 Edwards Lifesciences Corporation Prosthetic heart valve delivery system and method
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US9532873B2 (en) 2008-09-17 2017-01-03 Medtronic CV Luxembourg S.a.r.l. Methods for deployment of medical devices
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US9301840B2 (en) 2008-10-10 2016-04-05 Edwards Lifesciences Corporation Expandable introducer sheath
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US9326843B2 (en) 2009-01-16 2016-05-03 Claret Medical, Inc. Intravascular blood filters and methods of use
US8518073B2 (en) 2009-01-29 2013-08-27 Claret Medical, Inc. Illuminated intravascular blood filter
US8252051B2 (en) 2009-02-25 2012-08-28 Edwards Lifesciences Corporation Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
US8974489B2 (en) 2009-07-27 2015-03-10 Claret Medical, Inc. Dual endovascular filter and methods of use
US8753370B2 (en) 2009-07-27 2014-06-17 Claret Medical, Inc. Dual endovascular filter and methods of use
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US8926691B2 (en) 2009-12-04 2015-01-06 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US8986373B2 (en) 2009-12-04 2015-03-24 Edwards Lifesciences Corporation Method for implanting a prosthetic mitral valve
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9084676B2 (en) 2009-12-04 2015-07-21 Edwards Lifesciences Corporation Apparatus for treating a mitral valve
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US9925044B2 (en) 2010-04-01 2018-03-27 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
US9931206B2 (en) 2010-07-09 2018-04-03 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9375312B2 (en) 2010-07-09 2016-06-28 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9326853B2 (en) 2010-07-23 2016-05-03 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
US9345565B2 (en) 2010-12-30 2016-05-24 Claret Medical, Inc. Steerable dual filter cerebral protection system
US9017364B2 (en) 2010-12-30 2015-04-28 Claret Medical, Inc. Deflectable intravascular filter
US10058411B2 (en) 2010-12-30 2018-08-28 Claret Madical, Inc. Method of isolating the cerebral circulation during a cardiac procedure
US8876796B2 (en) 2010-12-30 2014-11-04 Claret Medical, Inc. Method of accessing the left common carotid artery
US9055997B2 (en) 2010-12-30 2015-06-16 Claret Medical, Inc. Method of isolating the cerebral circulation during a cardiac procedure
US9492264B2 (en) 2010-12-30 2016-11-15 Claret Medical, Inc. Embolic protection device for protecting the cerebral vasculature
US9259306B2 (en) 2010-12-30 2016-02-16 Claret Medical, Inc. Aortic embolic protection device
US9155619B2 (en) 2011-02-25 2015-10-13 Edwards Lifesciences Corporation Prosthetic heart valve delivery apparatus
US9289282B2 (en) 2011-05-31 2016-03-22 Edwards Lifesciences Corporation System and method for treating valve insufficiency or vessel dilatation
US8998976B2 (en) 2011-07-12 2015-04-07 Boston Scientific Scimed, Inc. Coupling system for medical devices
US9339384B2 (en) 2011-07-27 2016-05-17 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9119716B2 (en) 2011-07-27 2015-09-01 Edwards Lifesciences Corporation Delivery systems for prosthetic heart valve
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9168131B2 (en) 2011-12-09 2015-10-27 Edwards Lifesciences Corporation Prosthetic heart valve having improved commissure supports
US9414918B2 (en) 2012-09-06 2016-08-16 Edwards Lifesciences Corporation Heart valve sealing devices
US9510946B2 (en) 2012-09-06 2016-12-06 Edwards Lifesciences Corporation Heart valve sealing devices
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9168129B2 (en) 2013-02-12 2015-10-27 Edwards Lifesciences Corporation Artificial heart valve with scalloped frame design
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9913715B2 (en) 2013-11-06 2018-03-13 St. Jude Medical, Cardiology Division, Inc. Paravalvular leak sealing mechanism
US9566144B2 (en) 2015-04-22 2017-02-14 Claret Medical, Inc. Vascular filters, deflectors, and methods

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