ES2039254T3 - Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas. - Google Patents

Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas.

Info

Publication number
ES2039254T3
ES2039254T3 ES87400635T ES87400635T ES2039254T3 ES 2039254 T3 ES2039254 T3 ES 2039254T3 ES 87400635 T ES87400635 T ES 87400635T ES 87400635 T ES87400635 T ES 87400635T ES 2039254 T3 ES2039254 T3 ES 2039254T3
Authority
ES
Spain
Prior art keywords
derived
papilomavirus
genome
production
dna sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87400635T
Other languages
English (en)
Inventor
Stewart Cole
Rolf E Streeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Application granted granted Critical
Publication of ES2039254T3 publication Critical patent/ES2039254T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

LA INVENCION SE REFIERE A FRAGMENTOS DE ADN DERIVADOS DEL ADN GENOMICO DE HPV-33. ESTOS FRAGMENTOS SE SELECCIONAN DEL GRUPO DE FRAGMENTOS EXTENDIENDOSE ENTRE LAS EXTREMIDADES NUCLEOTIDAS DEFINIDAS AQUI ANTES EN RELACION CON LA NUMERACION DE NUCLEOTIDOS EN FIGS. 1A Y 1B REPECTIVAMENTE: 76-556 543-864 867-2811 2728-3808 3326-3575 3842-4079 4198-5611 5516-8091 LA INVENCION TAMBIEN SE REFIERE AL USO DE ESTOS FRAGMENTOS COMO PRUEBAS PARA LA DETECCION DE HPV EN CULTIVOS DE TEJIDOS.
ES87400635T 1986-03-21 1987-03-20 Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas. Expired - Lifetime ES2039254T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP86400609 1986-03-21

Publications (1)

Publication Number Publication Date
ES2039254T3 true ES2039254T3 (es) 1995-04-01

Family

ID=8196291

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87400635T Expired - Lifetime ES2039254T3 (es) 1986-03-21 1987-03-20 Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas.

Country Status (13)

Country Link
US (7) US5554538A (es)
EP (1) EP0243221B1 (es)
JP (2) JP2633275B2 (es)
KR (1) KR930007580B1 (es)
AT (1) ATE76429T1 (es)
AU (1) AU615159B2 (es)
DE (1) DE3779175D1 (es)
DK (1) DK175314B1 (es)
ES (1) ES2039254T3 (es)
FI (1) FI100057B (es)
GR (1) GR3005272T3 (es)
NO (1) NO303287B1 (es)
WO (1) WO1987005630A1 (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876922A (en) 1985-07-31 1999-03-02 Institute Pasteur Papillomavirus probe and a process for in vitro diagnosis of papillomavirus infections
ES2039254T3 (es) * 1986-03-21 1995-04-01 Pasteur Institut Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas.
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
WO1989009940A1 (en) * 1988-04-04 1989-10-19 Oncor, Inc. Human papilloma virus typing method and nucleic acid probes used therein
FR2632956B2 (fr) * 1988-05-13 1991-07-12 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55; produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55; procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
FR2631341B1 (fr) * 1988-05-13 1991-04-26 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55 et produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55 et procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
CA1339729C (en) * 1988-10-26 1998-03-17 Wayne D. Lancaster Human papillomavirus type 52 dna sequences and methods for employing thesame
SE8803870D0 (sv) * 1988-10-28 1988-10-28 Medscand Ab Method for detection of human papillomavirus (hpv) for diagnostic purposes
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
JPH05501650A (ja) * 1989-12-01 1993-04-02 バイシス・インコーポレーテツド Ｈｐｖ転写物の検出
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
FR2656627B1 (fr) * 1989-12-28 1992-04-17 Pasteur Institut Sonde a papillomavirus (hvpv63), notamment pour le diagnostic in vitro d'infections a papillomavirus, pouvant s'accompagner de neoplasies genitales, et produits genetiquement et immunologiquement lies a ce papillomavirus.
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
CA2052413C (en) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
US6183746B1 (en) * 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US7569344B2 (en) * 1998-10-26 2009-08-04 Ventana Medical Systems, Inc. Detection of human papilloma virus in papanicolaou (Pap) smears
WO2000061804A1 (en) * 1999-04-14 2000-10-19 Musc Foundation For Research Development Tissue-specific and pathogen-specific toxic agents and ribozymes
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
US20060275784A1 (en) * 1999-10-26 2006-12-07 Ventana Medical Systems, Inc. Detection of Human Papilloma Virus in Papanicolaou (Pap) Smears
DE60141205D1 (de) * 2000-04-03 2010-03-18 Cytyc Corp Nachweis und typisierung des papillomavirus mittels pna-sonden
US6936443B2 (en) * 2000-04-03 2005-08-30 Cytyc Corporation Detection and typing of human papillomavirus using PNA probes
US7312041B2 (en) * 2001-02-16 2007-12-25 Arbor Vita Corporation Methods of diagnosing cervical cancer
US20040229298A1 (en) * 2000-11-11 2004-11-18 Lu Peter S. Methods and compositions for treating cervical cancer
US20030059806A1 (en) * 2001-01-05 2003-03-27 Science & Technology Corporation @ Unm Probes for the detection of human papillomavirus
CN100422342C (zh) 2002-01-07 2008-10-01 诺奇普公司 检测人乳头瘤病毒mRNA的方法
HUP0200981A3 (en) 2002-03-14 2004-06-28 Genoid Kft Pcr reactions with hybridizing probes using primers with broad genotype-specificity for detection of human papilloma-viruses and typing amplificates by using specifically hybridizing oligonucleotides
JP2005537028A (ja) * 2002-06-26 2005-12-08 ザ　ペン　ステート　リサーチ　ファウンデーション ヒト乳頭腫ウイルス感染症を治療する方法及び材料
CA2495449A1 (en) 2002-09-09 2004-03-18 Arbor Vita Corporation Methods of diagnosing cervical cancer
JP2006503914A (ja) * 2002-10-21 2006-02-02 エムジーアイ ファーマ バイオロジックス インコーポレイテッド ヒトパピローマウイルス媒介性疾患を治療するための組成物および方法
BRPI0414801A (pt) 2003-09-25 2006-11-14 Third Wave Tech Inc detecção de hpv
JP5030594B2 (ja) 2003-12-23 2012-09-19 アルボー ビータ コーポレーション Ｈｐｖの発癌性株に対する抗体およびそれらの使用方法
AU2005314061B2 (en) 2004-12-08 2010-01-28 Gen-Probe Incorporated Detection of nucleic acids from multiple types of human papillomaviruses
AU2005313858B2 (en) * 2004-12-10 2011-04-07 Genera Biosystems Limited Human papilloma virus (HPV) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (FACS)
AU2006210792B2 (en) 2005-02-01 2012-07-26 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Papillomavirus L2 N-terminal peptides for the induction of broadly cross-neutralizing antibodies
US20070031826A1 (en) * 2005-08-05 2007-02-08 My Gene Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
US8278056B2 (en) * 2008-06-13 2012-10-02 Oncohealth Corp. Detection of early stages and late stages HPV infection
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
NZ580242A (en) * 2007-04-05 2012-02-24 Genera Biosystems Ltd Compositions and methods of detection of hpv infection
US8980562B1 (en) 2007-06-12 2015-03-17 Physicians Reference Laboratory Method of simultaneous detection and typing of human papilloma viruses
EP2427763A4 (en) 2009-05-07 2013-08-21 Oncohealth Corp IDENTIFICATION OF HIGH GRADE OR CIN2 FOR DETECTION, MONITORING AND DIAGNOSIS, AT EARLY STAGES AND ADVANCED STAGES, OF HUMAN PAPILLOMAVIRUS (HPV) AND HPV ASSOCIATED CANCERS
WO2011084598A1 (en) 2010-01-08 2011-07-14 Oncohealth Corporation High throughput cell-based hpv immunoassays for diagnosis and screening of hpv-associated cancers
WO2011094528A2 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of an hpv in a sample
EP2576840B1 (en) 2010-05-25 2018-10-17 QIAGEN Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically-truncated probes
CN102229660B (zh) * 2011-05-25 2015-04-22 厦门大学 截短的人乳头瘤病毒33型l1蛋白
CN104076150A (zh) * 2013-03-28 2014-10-01 沈萍萍 一种hpv-e6蛋白的检测方法
US9936943B1 (en) 2014-08-07 2018-04-10 Nicholas MANCINI Suture passing surgical device with atraumatic grasper preventing accidental perforations

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
FR2524487B1 (fr) * 1982-04-05 1985-11-22 Pasteur Institut Fragments d'adn codant pour des polypeptides contenant au moins un determinant antigenique des papillomavirus, notamment du type hpv 1a et polypeptides correspondants
US4748109A (en) * 1983-07-01 1988-05-31 Baird Phillip J Assay method and reagent to determine antibodies to papillomavirus virions
US5411857A (en) * 1985-07-31 1995-05-02 Institut Nationale De La Sante Probes for papillomaviruses and an in vitro diagnostic procedure for papilloma infections
CA1276575C (fr) * 1984-11-30 1990-11-20 Sylvie Beaudenon Sondes a papillomavirus et procede de diagnostic in vitro d'infections a papillomavirus
ATE79138T1 (de) * 1985-04-04 1992-08-15 Univ Georgetown Typenspezifische papillomavirus-dns-sequenzen und peptide.
FR2586428B1 (fr) * 1985-08-26 1988-11-25 Pasteur Institut Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus
ES2039254T3 (es) * 1986-03-21 1995-04-01 Pasteur Institut Secuencias determinadas de adn, derivadas de un genoma de papilomavirus, sus usos con finalidades de diagnostico in vitro y la produccion de composiciones antigenas.
US4849322A (en) * 1986-04-30 1989-07-18 E. I. Du Pont De Nemours And Company Positive-working color proofing film and process
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
US4849331A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 44 nucleic acid hybridization probes and methods for employing the same
US4849334A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 43 nucleic acid hybridization probes and methods for employing the same
US4849332A (en) * 1987-05-26 1989-07-18 Life Technologies, Inc. Human papillomavirus 35 nucleic acid hybridization probes and methods for employing the same
DE3722967A1 (de) * 1987-07-11 1989-01-19 Behringwerke Ag Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
US5182377A (en) * 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus
DE3935592A1 (de) * 1989-10-26 1991-05-02 Hella Kg Hueck & Co Verfahren und einrichtung zur regelung der innenraumtemperatur von kraftfahrzeugen
JPH05501650A (ja) * 1989-12-01 1993-04-02 バイシス・インコーポレーテツド Ｈｐｖ転写物の検出
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
CA2052413C (en) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
IT1244462B (it) * 1990-12-06 1994-07-15 Sclavo Spa Oligonucleotidi sintetici utili per la diagnosi di infezione da tipi diversi di virus del gruppo papilloma e loro utilizzazione

Also Published As

Publication number Publication date
US6242250B1 (en) 2001-06-05
DE3779175D1 (de) 1992-06-25
AU615159B2 (en) 1991-09-26
US6107086A (en) 2000-08-22
DK175314B1 (da) 2004-08-16
US5876723A (en) 1999-03-02
NO303287B1 (no) 1998-06-22
JPS63502798A (ja) 1988-10-20
EP0243221A1 (en) 1987-10-28
JP2633275B2 (ja) 1997-07-23
US6344314B2 (en) 2002-02-05
AU7200787A (en) 1987-10-09
US20010049137A1 (en) 2001-12-06
US7063963B2 (en) 2006-06-20
NO874750L (no) 1987-11-13
EP0243221B1 (en) 1992-05-20
ATE76429T1 (de) 1992-06-15
NO874750D0 (no) 1987-11-13
US20040132012A1 (en) 2004-07-08
GR3005272T3 (es) 1993-05-24
JPH09117294A (ja) 1997-05-06
JP2735537B2 (ja) 1998-04-02
FI100057B (fi) 1997-09-15
US5648459A (en) 1997-07-15
KR930007580B1 (ko) 1993-08-13
DK605987A (da) 1987-11-18
US5554538A (en) 1996-09-10
WO1987005630A1 (en) 1987-09-24
FI875082A0 (fi) 1987-11-17
DK605987D0 (da) 1987-11-18
FI875082A (fi) 1987-11-17

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