AR021143A1 - Identificacion de genotipos senv - Google Patents

Identificacion de genotipos senv

Info

Publication number
AR021143A1
AR021143A1 ARP990105694A ARP990105694A AR021143A1 AR 021143 A1 AR021143 A1 AR 021143A1 AR P990105694 A ARP990105694 A AR P990105694A AR P990105694 A ARP990105694 A AR P990105694A AR 021143 A1 AR021143 A1 AR 021143A1
Authority
AR
Argentina
Prior art keywords
nucleic acid
acid molecule
virus
genome
peptide
Prior art date
Application number
ARP990105694A
Other languages
English (en)
Original Assignee
Diasorin International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITMI982437 external-priority patent/IT1303732B1/it
Priority claimed from ITMI990923 external-priority patent/IT1312552B1/it
Application filed by Diasorin International Inc filed Critical Diasorin International Inc
Publication of AR021143A1 publication Critical patent/AR021143A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se refiere a una molécula de ácido nucleico que representa el genoma de un virus/agente vírico, poseyendo dicha molécula de ácido nucleico como mínimouna de las siguientes características: (a) contiene como mínimo un marco de lectura abierto (ORF) que codifica un polipéptido que tiene una secuencia deaminoácidos aquí descrita, (b) comprende una secuencia de DNA como la aquí descrita; (c) hibrida preferentemente en condiciones restrictivas con lahebra complementaria de la molécula de ácido nucleico aquí descrita, pero no con la hebra complementaria del genoma del virus TT; (d) es degenerada conrespecto a la molécula de ácido nucleico que hibrida; (e) es como mínimo 60% idéntica a la molécula de ácido nucleico que representa el genoma del virus/agente vírico de la invencion; y (f) partes de ella pueden amplificarse por PCR en condiciones adecuadas utilizando iniciadores como los aquídescritos. Se refiere además a vectores que comprenden dicha molécula de ácido nucleico, métodos de producir (poli) péptido(s) codificados por dichamolécula de ácido nucleico, a los virus/agentes víricos que incorporan un genoma representado por dicha molécula de ácido nucleico y anticuerposcontra dichos (poli)péptido(s) y/o dichos virus/agentes víricos.Adicionalmente, la invencion se refiere a composiciones, preferentemente composicionesfarmacéuticas, vacunas, reactivos de diagnostico y kits de diagnostico que incluyen o utilizan los compuestos de la invencion.
ARP990105694A 1998-11-10 1999-11-10 Identificacion de genotipos senv AR021143A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITMI982437 IT1303732B1 (it) 1998-11-10 1998-11-10 Molecole di acido nucleico che rappresentano un virus trasmissibileper via parenterale.
ITMI990923 IT1312552B1 (it) 1999-04-30 1999-04-30 Molecole di acido nucleico che rappresentano un virus trasmissibileper via parenterale
EP99830298 1999-05-14
EP99113932 1999-07-16

Publications (1)

Publication Number Publication Date
AR021143A1 true AR021143A1 (es) 2002-06-12

Family

ID=27443821

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990105694A AR021143A1 (es) 1998-11-10 1999-11-10 Identificacion de genotipos senv

Country Status (8)

Country Link
EP (1) EP1137779A2 (es)
JP (1) JP2002529092A (es)
AR (1) AR021143A1 (es)
AU (1) AU1381600A (es)
NO (1) NO20012276L (es)
PE (1) PE20001331A1 (es)
TN (1) TNSN99210A1 (es)
WO (1) WO2000028039A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003516136A (ja) * 1999-12-10 2003-05-13 ロシュ ダイアグノスティックス ゲーエムベーハー 肝炎ウイルスセンチネルウイルスｉ（ｓｖｉ）
DE10007234A1 (de) * 2000-02-17 2001-10-18 Sension Biolog Detektions Und Peptid und dafür kodierende Nukleinsäure zur Bestimmung, Diagnostik und Therapie von Erkrankungen des Nervensystems
DE10144346A1 (de) * 2001-09-10 2003-04-03 Deutsches Krebsforsch TT-Virus-Sequenzen in menschlichen Tumorgeweben, Mittel zu deren Nachweis sowie Tumortherapie
US20110318363A1 (en) 2010-06-23 2011-12-29 Deutsches Krebsforschungszentrum Specific TT virus sequences and chimeric TT virus host cell DNA molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity
DK2399928T3 (da) * 2010-06-23 2018-01-29 Deutsches Krebsforsch Specifikke TT-virus-sekvenser og kimæriske TT-virusværtscelle-DNA-molekyler til anvendelse ved diagnosticering, forebyggelse og behandling af cancer og auto-immunitet
WO2011160848A1 (en) * 2010-06-23 2011-12-29 Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Rechtes Rearranged tt virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity
US9676828B2 (en) 2010-06-23 2017-06-13 Deutsches Krebsforschungszentrum Rearranged TT virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010022220A (ko) * 1997-07-25 2001-03-15 다무라 료지 비-ｂ형 비-ｃ형 비-ｇ형 간염 바이러스 유전자,폴리뉴클레오티드, 폴리펩티드, 바이러스 입자, 바이러스입자의 분리 방법, 및 바이러스의 검출 방법
WO1999058638A2 (en) * 1998-05-13 1999-11-18 Innogenetics N.V. Sequences of tt viruses for use in diagnosis, prevention and treatment of ttv infections

Also Published As

Publication number Publication date
JP2002529092A (ja) 2002-09-10
PE20001331A1 (es) 2000-12-19
TNSN99210A1 (fr) 2005-11-10
NO20012276L (no) 2001-07-09
WO2000028039A3 (en) 2000-10-05
WO2000028039A2 (en) 2000-05-18
NO20012276D0 (no) 2001-05-09
EP1137779A2 (en) 2001-10-04
AU1381600A (en) 2000-05-29

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