ES2039194T3 - Un metodo de preparar una composicion farmaceutica tromboliticamente activa. - Google Patents

Un metodo de preparar una composicion farmaceutica tromboliticamente activa.

Info

Publication number
ES2039194T3
ES2039194T3 ES198686115665T ES86115665T ES2039194T3 ES 2039194 T3 ES2039194 T3 ES 2039194T3 ES 198686115665 T ES198686115665 T ES 198686115665T ES 86115665 T ES86115665 T ES 86115665T ES 2039194 T3 ES2039194 T3 ES 2039194T3
Authority
ES
Spain
Prior art keywords
thrombolitically
preparing
pharmaceutical composition
active pharmaceutical
plasminogen activators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686115665T
Other languages
English (en)
Inventor
Desire Jose Collen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Application granted granted Critical
Publication of ES2039194T3 publication Critical patent/ES2039194T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ACTIVADORES DE PLASMINOGENO DEL TIPO TEJIDO Y ACTIVADORES DE PLASMINOGENO DEL TIPO UROQUINASA PARECEN TENER UNA ACCION SINERGICA EN VIVO CUANDO SE SUMINISTRAN JUNTOS COMO AGENTES TROMBOLITICOS. ESTO SE PUEDE UTILIZAR EN COMPOSICIONES FARMACEUTICAS Y EN METODOS PARA SU PREPARACION Y USO.
ES198686115665T 1985-11-11 1986-11-11 Un metodo de preparar una composicion farmaceutica tromboliticamente activa. Expired - Lifetime ES2039194T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8503097A NL8503097A (nl) 1985-11-11 1985-11-11 Geneesmiddel met thrombolytische werking.

Publications (1)

Publication Number Publication Date
ES2039194T3 true ES2039194T3 (es) 1993-09-16

Family

ID=19846844

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686115665T Expired - Lifetime ES2039194T3 (es) 1985-11-11 1986-11-11 Un metodo de preparar una composicion farmaceutica tromboliticamente activa.

Country Status (17)

Country Link
EP (1) EP0223192B1 (es)
JP (1) JPH089546B2 (es)
AT (1) ATE64532T1 (es)
AU (1) AU586713B2 (es)
CA (1) CA1303987C (es)
DE (1) DE3679887D1 (es)
DK (1) DK164640C (es)
ES (1) ES2039194T3 (es)
GR (1) GR3002226T3 (es)
HU (1) HU196715B (es)
IE (1) IE59387B1 (es)
IL (1) IL80538A (es)
NL (1) NL8503097A (es)
NZ (1) NZ218231A (es)
PH (1) PH23192A (es)
PT (1) PT83721B (es)
ZA (1) ZA868464B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8623823D0 (en) * 1986-10-03 1986-11-05 Sandoz Ltd Therapeutic lysis of fibrin blood clots
SE462829B (sv) * 1989-01-10 1990-09-10 Kabigen Ab Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas
EP0472657B1 (en) * 1989-05-17 1996-03-13 Research Corporation Technologies, Inc. Method and composition for the treatment of thrombosis in a mammal
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1642612A1 (de) * 1967-03-02 1971-09-09 Bayer Ag Die Verwendung von Erythrozyten zur Gewinnung bzw.Isolierung eines Plasminogen-Aktivators
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
SU1662352A3 (ru) * 1982-05-05 1991-07-07 Генентек, Инк (Фирма) Штамм бактерий ЕSснеRIснIа coLI - продуцент активатора плазминогена тканевого типа
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
JPH0637398B2 (ja) * 1982-10-29 1994-05-18 三井東圧化学株式会社 血栓溶解剤
JPS59139323A (ja) * 1983-01-28 1984-08-10 Green Cross Corp:The ウロキナ−ゼ乾燥製剤
JPS6051119A (ja) * 1983-08-30 1985-03-22 Green Cross Corp:The ウロキナ−ゼ乾燥製剤
JPS60152421A (ja) * 1984-01-23 1985-08-10 Sanwa Kagaku Kenkyusho:Kk ヒト胎盤性プラスミノ−ゲン活性化因子、及びそれとヒトプラスミノ−ゲン活性化阻害因子との結合物、及びそれらの製法
GB8430253D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
WO1987006836A1 (en) * 1986-05-15 1987-11-19 Emory University Fibrinolytic composition
HUT47032A (en) * 1986-10-03 1989-01-30 Sandoz Ag Process for production of medical compositions dissolving blood cut

Also Published As

Publication number Publication date
IL80538A (en) 1991-06-30
JPS62155222A (ja) 1987-07-10
EP0223192A1 (en) 1987-05-27
DK164640C (da) 1992-12-14
GR3002226T3 (en) 1992-12-30
HUT43794A (en) 1987-12-28
IE862962L (en) 1987-05-11
AU6503186A (en) 1987-05-14
NL8503097A (nl) 1987-06-01
IL80538A0 (en) 1987-02-27
JPH089546B2 (ja) 1996-01-31
DK532886D0 (da) 1986-11-07
DK532886A (da) 1987-05-12
NZ218231A (en) 1988-10-28
PT83721A (en) 1986-12-01
PH23192A (en) 1989-05-29
ATE64532T1 (de) 1991-07-15
HU196715B (en) 1989-01-30
CA1303987C (en) 1992-06-23
ZA868464B (en) 1987-06-24
DE3679887D1 (de) 1991-07-25
DK164640B (da) 1992-07-27
PT83721B (pt) 1988-08-17
IE59387B1 (en) 1994-02-23
EP0223192B1 (en) 1991-06-19
AU586713B2 (en) 1989-07-20

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