DE69000290D1 - Thrombotische zusammensetzungen. - Google Patents

Thrombotische zusammensetzungen.

Info

Publication number
DE69000290D1
DE69000290D1 DE9090850008T DE69000290T DE69000290D1 DE 69000290 D1 DE69000290 D1 DE 69000290D1 DE 9090850008 T DE9090850008 T DE 9090850008T DE 69000290 T DE69000290 T DE 69000290T DE 69000290 D1 DE69000290 D1 DE 69000290D1
Authority
DE
Germany
Prior art keywords
thrombotic
treating
compositions
streptokinase
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090850008T
Other languages
English (en)
Other versions
DE69000290T2 (de
Inventor
Gunnar Pohl
Christer Mattsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Kabigen AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabigen AB filed Critical Kabigen AB
Publication of DE69000290D1 publication Critical patent/DE69000290D1/de
Application granted granted Critical
Publication of DE69000290T2 publication Critical patent/DE69000290T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE9090850008T 1989-01-10 1990-01-08 Thrombotische zusammensetzungen. Expired - Fee Related DE69000290T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8900067A SE462829B (sv) 1989-01-10 1989-01-10 Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas

Publications (2)

Publication Number Publication Date
DE69000290D1 true DE69000290D1 (de) 1992-10-15
DE69000290T2 DE69000290T2 (de) 1993-04-22

Family

ID=20374707

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090850008T Expired - Fee Related DE69000290T2 (de) 1989-01-10 1990-01-08 Thrombotische zusammensetzungen.

Country Status (11)

Country Link
US (1) US5202121A (de)
EP (1) EP0381640B1 (de)
JP (1) JP2958650B2 (de)
AT (1) ATE80308T1 (de)
AU (1) AU624466B2 (de)
CA (1) CA2007075C (de)
DE (1) DE69000290T2 (de)
DK (1) DK0381640T3 (de)
ES (1) ES2044534T3 (de)
GR (1) GR3006053T3 (de)
SE (1) SE462829B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6682733B1 (en) * 1987-06-18 2004-01-27 Roche Diagnostics, Gmbh Fibrinolytic enzymes
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions
US6020181A (en) * 1995-05-17 2000-02-01 New York Blood, Inc. Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase
US5830468A (en) * 1995-05-17 1998-11-03 The New York Blood Center, Inc. Fibrin(ogen) degradation by fibrinolytic matrix metalloproteinase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8503097A (nl) * 1985-11-11 1987-06-01 Leuven Res & Dev Vzw Geneesmiddel met thrombolytische werking.
EP0293394B2 (de) * 1986-01-31 2003-10-29 Genetics Institute, LLC Neue thrombolytische proteine
PT84589B (en) * 1986-04-02 1989-05-09 Beecham Group Plc Process for preparing a fibrinolytic enzyme
NL8701021A (nl) * 1987-04-29 1988-11-16 Stichting Centraal Lab Humane t-pa(u-pa) substitutie-mutant eiwitten, daarvoor coderend recombinant dna, getransfecteerde gastheercellen, bereiding van de mutant eiwitten, en farmaceutische preparaten.
US4935237A (en) * 1988-03-21 1990-06-19 Genentech, Inc. Processes for the preparation of t-PA mutants
US4963357A (en) * 1987-10-09 1990-10-16 Monsanto Company Tissue plasminogen activator modified by the substitution of Arg for Cys at position 73, methods and pharmaceutical compositions therefor
DE3741149A1 (de) * 1987-12-04 1989-06-15 Thomae Gmbh Dr K Zubereitungsformen zur verhinderung von adhaesionen von organen und organteilen

Also Published As

Publication number Publication date
CA2007075C (en) 2002-03-19
CA2007075A1 (en) 1990-07-10
DK0381640T3 (da) 1992-12-21
EP0381640A1 (de) 1990-08-08
SE8900067D0 (sv) 1989-01-10
AU4776890A (en) 1990-08-30
EP0381640B1 (de) 1992-09-09
ATE80308T1 (de) 1992-09-15
SE462829B (sv) 1990-09-10
SE8900067A (de) 1989-01-10
ES2044534T3 (es) 1994-01-01
DE69000290T2 (de) 1993-04-22
JPH02225420A (ja) 1990-09-07
JP2958650B2 (ja) 1999-10-06
AU624466B2 (en) 1992-06-11
GR3006053T3 (de) 1993-06-21
US5202121A (en) 1993-04-13

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER PATENTINHABER LAUTET RICHTIG: KABI PHARMACIA AB, UPPSALA, SE

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN AB, STOCKHOLM, SE

8339 Ceased/non-payment of the annual fee