ES2012510A6 - Procedimiento para la produccion de derivados de calcitonina - Google Patents

Procedimiento para la produccion de derivados de calcitonina

Info

Publication number
ES2012510A6
ES2012510A6 ES8603267A ES8603267A ES2012510A6 ES 2012510 A6 ES2012510 A6 ES 2012510A6 ES 8603267 A ES8603267 A ES 8603267A ES 8603267 A ES8603267 A ES 8603267A ES 2012510 A6 ES2012510 A6 ES 2012510A6
Authority
ES
Spain
Prior art keywords
radical
alpha
amino acid
aminoacyl
calcitonin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8603267A
Other languages
English (en)
Spanish (es)
Inventor
Francois Cardinaux
Janos Pless
Robert Helmut Buck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2012510A6 publication Critical patent/ES2012510A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES8603267A 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina Expired - Lifetime ES2012510A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3542859 1985-12-04
DE3614784 1986-05-02

Publications (1)

Publication Number Publication Date
ES2012510A6 true ES2012510A6 (es) 1990-04-01

Family

ID=25838500

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603267A Expired - Lifetime ES2012510A6 (es) 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina

Country Status (20)

Country Link
US (1) US4758550A (OSRAM)
JP (1) JPH085916B2 (OSRAM)
KR (1) KR880006263A (OSRAM)
AU (1) AU600242B2 (OSRAM)
BE (1) BE905849A (OSRAM)
CH (1) CH671229A5 (OSRAM)
DK (1) DK580186A (OSRAM)
ES (1) ES2012510A6 (OSRAM)
FI (1) FI864939A7 (OSRAM)
FR (1) FR2590902B1 (OSRAM)
GB (1) GB2184729B (OSRAM)
GR (1) GR862836B (OSRAM)
HU (1) HUT44794A (OSRAM)
IL (1) IL80846A0 (OSRAM)
IT (1) IT1214754B (OSRAM)
LU (1) LU86697A1 (OSRAM)
NL (1) NL8602950A (OSRAM)
NZ (1) NZ218473A (OSRAM)
PT (1) PT83835B (OSRAM)
SE (1) SE8605189L (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0298474B1 (en) * 1987-07-08 1992-11-19 Mitsubishi Petrochemical Co., Ltd. Novel calcitonin derivative and salt thereof
AU609911B2 (en) * 1987-12-16 1991-05-09 Rorer International (Overseas) Inc. 8-glycine,16-x, des-19-leucine-calcitonin
GB2218102B (en) * 1988-04-08 1992-09-16 Sandoz Ltd Calcitonin peptide derivatives
US5153308A (en) * 1988-06-16 1992-10-06 Teijin Limited S-sulfonated calcitonin derivatives
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
DE68912090T2 (de) * 1988-11-24 1994-06-16 Mitsubishi Petrochemical Co Calcitonin-Derivate und deren Salze.
FI913899A7 (fi) * 1989-02-23 1991-08-19 Rorer Int Holdings Inc Terapeuttiset aerosoliseokset
US5204326A (en) * 1989-03-16 1993-04-20 Otsuka Pharmaceutical Co., Ltd. Polypeptide derivatives and calcium metabolism improving agent
WO1990012809A1 (en) * 1989-04-21 1990-11-01 Tsumura & Co. Novel physiologically active peptide and calcium metabolism-regulating agent comprising said peptide as effective ingredient
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
US5175146A (en) * 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides
CS89491A3 (en) * 1990-04-09 1992-01-15 Chugai Pharmaceutical Co Ltd Hybrid calcitonin
US5710244A (en) * 1992-12-31 1998-01-20 Labroo; Virender M. Derivatized calcitonins
WO1994015962A2 (en) * 1992-12-31 1994-07-21 Zymogenetics, Inc. Derivatized calcitonins
WO1995021622A1 (en) * 1994-02-09 1995-08-17 Brigham & Women's Hospital Gel-forming polypeptide derivatives
EP0726075A1 (en) * 1995-02-08 1996-08-14 Therapicon Srl Pharmaceutical non-inorganic saline solutions for endonasal administration
KR960031478A (ko) * 1995-02-14 1996-09-17 성재갑 유비퀴틴 융합 인간 칼시토닌의 정제방법
US6034064A (en) * 1995-04-07 2000-03-07 Hoechst Pharmaceuticals & Chemicals K.K. Peptides and therapeutic agent for autoimmune diseases containing the same
US5721207A (en) * 1995-04-18 1998-02-24 Innapharma, Inc. Method for treatment of pain
JP4372345B2 (ja) 1998-02-13 2009-11-25 アミリン・ファーマシューティカルズ,インコーポレイテッド 新規な混合アミリン活性化合物
US6936584B1 (en) 1998-02-13 2005-08-30 Amylin Pharmaceuticals, Inc. Mixed amylin activity compounds
US8653238B2 (en) * 2006-02-27 2014-02-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for transport of molecules with enhanced release properties across biological barriers
CN104011066A (zh) * 2011-12-09 2014-08-27 加利福尼亚大学董事会 经修饰的微型铁调素肽及其使用方法
WO2013162729A1 (en) 2012-04-24 2013-10-31 The Board Of Trustees Of The Leland Stanford Junior University Method for delivery of small molecules and proteins across the cell wall of algae using molecular transporters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926938A (en) * 1974-08-12 1975-12-16 Armour Pharma Synthesis of salmon calcitonin
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
GB1592969A (en) * 1976-09-13 1981-07-15 Armour Pharma Hentriacontapeptides and preparation thereof
WO1984003279A1 (en) * 1983-02-15 1984-08-30 Armour Pharma Des-asparagine-3 calcitonin
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
GB8327346D0 (en) * 1983-10-12 1983-11-16 Morris H R Peptide
US4497732A (en) * 1983-10-21 1985-02-05 Armour Pharmaceutical Company 1A-Endo-glycine-calcitonin
US4537716A (en) * 1983-12-05 1985-08-27 Armour Pharmaceutical Co. Des-serine2 or des-glycine2 -leucine22 calcitonin
US4622386A (en) * 1985-03-28 1986-11-11 Armour Pharmaceutical Company [1,7-di-alanine]calcitonin
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
AU7468687A (en) * 1987-06-23 1989-01-05 Armour Pharmaceutical Company (n-acyl, 1,7-di-alanine) calcitonin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Also Published As

Publication number Publication date
IT8648701A0 (it) 1986-12-04
AU600242B2 (en) 1990-08-09
IT1214754B (it) 1990-01-18
PT83835B (pt) 1989-06-30
DK580186D0 (da) 1986-12-02
KR880006263A (ko) 1988-07-22
HUT44794A (en) 1988-04-28
FI864939A7 (fi) 1987-06-05
NL8602950A (nl) 1987-07-01
DK580186A (da) 1987-06-05
FR2590902A1 (fr) 1987-06-05
PT83835A (en) 1986-12-01
NZ218473A (en) 1990-03-27
FI864939A0 (fi) 1986-12-03
SE8605189D0 (sv) 1986-12-03
GB2184729B (en) 1990-07-25
GB2184729A (en) 1987-07-01
AU6606186A (en) 1987-06-11
GR862836B (en) 1987-04-02
GB8628739D0 (en) 1987-01-07
JPH085916B2 (ja) 1996-01-24
JPS62132898A (ja) 1987-06-16
US4758550A (en) 1988-07-19
CH671229A5 (OSRAM) 1989-08-15
IL80846A0 (en) 1987-03-31
SE8605189L (sv) 1987-06-05
BE905849A (fr) 1987-06-03
FR2590902B1 (fr) 1994-12-23
LU86697A1 (fr) 1987-07-24

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