ES2007177A6 - Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2. - Google Patents
Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2.Info
- Publication number
- ES2007177A6 ES2007177A6 ES8801031A ES8801031A ES2007177A6 ES 2007177 A6 ES2007177 A6 ES 2007177A6 ES 8801031 A ES8801031 A ES 8801031A ES 8801031 A ES8801031 A ES 8801031A ES 2007177 A6 ES2007177 A6 ES 2007177A6
- Authority
- ES
- Spain
- Prior art keywords
- thioamides
- purinyl
- amino
- beta
- acid amides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003556 thioamides Chemical class 0.000 title abstract 2
- TZUIYQSTNVLSSW-GKVYFZHNSA-N (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-3,4,5-trihydroxyoxolane-2-carboxamide Chemical class NC1=C2N=CN(C2=NC=N1)[C@]1(O)[C@H](O)[C@H](O)[C@H](O1)C(=O)N TZUIYQSTNVLSSW-GKVYFZHNSA-N 0.000 title 1
- -1 6-AMINO-9-PURINYL Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3711562 | 1987-04-06 | ||
| DE3711561 | 1987-04-06 | ||
| DE3711563 | 1987-04-06 | ||
| DE3711564 | 1987-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2007177A6 true ES2007177A6 (es) | 1989-06-01 |
Family
ID=27433888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8801031A Expired ES2007177A6 (es) | 1987-04-06 | 1988-04-05 | Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2. |
Country Status (22)
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755594A (en) * | 1986-01-31 | 1988-07-05 | Warner-Lambert Company | N6 -substituted adenosines |
| US4954504A (en) * | 1986-11-14 | 1990-09-04 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity |
| US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
| HU198950B (en) * | 1986-12-15 | 1989-12-28 | Sandoz Ag | Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds |
| EP0277917A3 (en) * | 1987-02-04 | 1990-03-28 | Ciba-Geigy Ag | Certain adenosine 5'-carboxamide derivatives |
| US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
| US5140015A (en) * | 1990-02-20 | 1992-08-18 | Whitby Research, Inc. | 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents |
| USRE36494E (en) * | 1990-02-20 | 2000-01-11 | Discovery Therapeutics, Inc. | 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents |
| IT1254915B (it) * | 1992-04-24 | 1995-10-11 | Gloria Cristalli | Derivati di adenosina ad attivita' a2 agonista |
| GB9301000D0 (en) * | 1993-01-20 | 1993-03-10 | Glaxo Group Ltd | Chemical compounds |
| TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| CZ20004868A3 (cs) | 1998-06-23 | 2001-08-15 | Glaxo Group Limited | 2-(Purin-9-yl)-tetrahydrofuran-3,4-diolové deriváty, způsob jejich přípravy a fármaceutické prostředky, které je obsahují |
| AU4343500A (en) | 1999-04-16 | 2000-11-02 | Schering Corporation | Use of azetidinone compounds |
| US20050033044A1 (en) | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
| AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| ATE531377T1 (de) * | 2004-09-20 | 2011-11-15 | Inotek Pharmaceuticals Corp | Purin-derivate und anwendungsverfahren |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH606084A5 (en) * | 1975-02-18 | 1978-10-13 | Hoffmann La Roche | (Di) nitrates of adenosine -5'-carboxylic acid derivs |
| US4167565A (en) * | 1976-11-08 | 1979-09-11 | Abbott Laboratories | Adenosine-5'-carboxamides and method of use |
| DE3406533A1 (de) * | 1984-02-23 | 1985-08-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten |
| HU198950B (en) * | 1986-12-15 | 1989-12-28 | Sandoz Ag | Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds |
| EP0277917A3 (en) * | 1987-02-04 | 1990-03-28 | Ciba-Geigy Ag | Certain adenosine 5'-carboxamide derivatives |
-
1988
- 1988-03-28 LU LU87181A patent/LU87181A1/fr unknown
- 1988-03-30 FR FR8804356A patent/FR2613367A1/fr not_active Withdrawn
- 1988-03-30 IT IT47794/88A patent/IT1219892B/it active
- 1988-03-30 BE BE8800374A patent/BE1002151A5/fr not_active IP Right Cessation
- 1988-03-31 CH CH1228/88A patent/CH676121A5/de not_active IP Right Cessation
- 1988-03-31 GB GB8807750A patent/GB2203149B/en not_active Expired - Lifetime
- 1988-04-04 IL IL85969A patent/IL85969A/xx not_active IP Right Cessation
- 1988-04-04 MY MYPI88000344A patent/MY102323A/en unknown
- 1988-04-04 PH PH36731A patent/PH25424A/en unknown
- 1988-04-04 KR KR1019880003819A patent/KR880012629A/ko not_active Ceased
- 1988-04-04 PT PT87153A patent/PT87153B/pt active IP Right Grant
- 1988-04-05 CA CA000563261A patent/CA1326017C/en not_active Expired - Fee Related
- 1988-04-05 NL NL8800862A patent/NL8800862A/nl not_active Application Discontinuation
- 1988-04-05 HU HU881638A patent/HU201955B/hu not_active IP Right Cessation
- 1988-04-05 SE SE8801236A patent/SE8801236L/xx unknown
- 1988-04-05 AU AU14151/88A patent/AU609109B2/en not_active Ceased
- 1988-04-05 ES ES8801031A patent/ES2007177A6/es not_active Expired
- 1988-04-05 JP JP63084974A patent/JPS63258892A/ja active Pending
- 1988-04-05 AT AT873/88A patent/AT393507B/de not_active IP Right Cessation
- 1988-04-05 DK DK183488A patent/DK183488A/da not_active Application Discontinuation
- 1988-04-05 FI FI881571A patent/FI87463C/fi not_active IP Right Cessation
- 1988-04-06 NZ NZ224131A patent/NZ224131A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2007177A6 (es) | Procedimiento para preparar amidas y tioamidas del acido 1'-desoxi-1'-(6-amino-9-purinil)-b-d-ribofuranuronico sustituidas en la posicion 2. | |
| ATE181064T1 (de) | Fibrinogen-rezeptor-antagonisten | |
| MX9203338A (es) | Nuevos derivados del oxico a_nor-esteroide-3-carboxilico. | |
| DE69230013D1 (de) | Fibrinogen-Rezeptor-Antagonisten | |
| DK0512829T3 (da) | Fibrinogenreceptorantagonister | |
| ES2056071T3 (es) | Triazolinonas substituidas. | |
| MY103352A (en) | Piperazinyl-heterocyclic compounds | |
| ATE145201T1 (de) | Dihydro-isoquinolinderivate | |
| DE69021501D1 (de) | Anti-entzündende 4-aminophenol-derivate. | |
| ATE154230T1 (de) | Haarwuchsmittel | |
| DK192988D0 (da) | Dihydropyridinamider, deres fremstilling og anvendelse | |
| MY103210A (en) | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds. | |
| MY132057A (en) | Quinoxalinones, a process for their preparation and their use | |
| DK0505400T3 (da) | N-substituerede naphthalimider, deres fremstilling og anvendelse | |
| DE3861271D1 (de) | Basisch substituierte benzofurancarbonsaeureamide, verfahren zu ihrer herstellung und sie enthaltende therapeutische mittel. | |
| FI910177A7 (fi) | Menetelmä pyridiini-2,4- ja pyridiini-2,5-dikarboksyyli-happodi-(nitr oksialkyyli)amidien valmistamiseksi ja niiden käyttö | |
| IT1241927B (it) | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono | |
| DK0418990T3 (da) | 13-brom- og 13,14-dibrom-ergoliner, deres fremstilling og anvendelse i lægemidler | |
| ATE89555T1 (de) | 3-substituierte 1-(2-halogen-alkoxybenzolsulfonyl)-3-heteroaryl-harnstoffe. | |
| ES8800666A1 (es) | Procedimiento para la obtencion de derivados de 1,4-dihidropiridina | |
| DK514786D0 (da) | 5-heterocyclyl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner og tautomere og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelsesom antidepressive midler | |
| NZ193663A (en) | 2-(2-phenylthioethyl) malonic acid n,n'-diphenyl hydrazide salts and esters antithrombic pharmaceutical compositions | |
| FI913161A7 (fi) | Menetelmä N-(3',4'-dimetoksikinnamoyyli)antraniilihapon valmistamiseks i | |
| ES8606298A1 (es) | 1.4-dihidropirazinas |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000301 |