ES2001618A6 - Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura. - Google Patents

Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura.

Info

Publication number
ES2001618A6
ES2001618A6 ES8601490A ES8601490A ES2001618A6 ES 2001618 A6 ES2001618 A6 ES 2001618A6 ES 8601490 A ES8601490 A ES 8601490A ES 8601490 A ES8601490 A ES 8601490A ES 2001618 A6 ES2001618 A6 ES 2001618A6
Authority
ES
Spain
Prior art keywords
yeast
procedure
preparation
repressible
water above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601490A
Other languages
English (en)
Spanish (es)
Inventor
Albert Hinnen
Bernd Meyhack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES2001618A6 publication Critical patent/ES2001618A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Led Devices (AREA)
  • Gyroscopes (AREA)
  • Graft Or Block Polymers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
ES8601490A 1985-08-29 1986-08-29 Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura. Expired ES2001618A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858521496A GB8521496D0 (en) 1985-08-29 1985-08-29 Repressible yeast promoters

Publications (1)

Publication Number Publication Date
ES2001618A6 true ES2001618A6 (es) 1988-06-01

Family

ID=10584428

Family Applications (3)

Application Number Title Priority Date Filing Date
ES8601490A Expired ES2001618A6 (es) 1985-08-29 1986-08-29 Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura.
ES8800794A Expired ES2006382A6 (es) 1985-08-29 1988-03-16 Procedimiento para la preparacion de un polipeptido mediante levadura que contiene un promotor hibrido con los puntos de activacion aguas arriba del gen pho5 de levadura.
ES8800795A Expired ES2006383A6 (es) 1985-08-29 1988-03-16 Procedimiento para la preparacion de vectores hibridos de levadura comprendiendo promotores de levadura represibles con los lugares de actuacion aguas arriba del gen ph05 de levadura.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES8800794A Expired ES2006382A6 (es) 1985-08-29 1988-03-16 Procedimiento para la preparacion de un polipeptido mediante levadura que contiene un promotor hibrido con los puntos de activacion aguas arriba del gen pho5 de levadura.
ES8800795A Expired ES2006383A6 (es) 1985-08-29 1988-03-16 Procedimiento para la preparacion de vectores hibridos de levadura comprendiendo promotores de levadura represibles con los lugares de actuacion aguas arriba del gen ph05 de levadura.

Country Status (22)

Country Link
US (1) US5436136A (https=)
EP (1) EP0213593B1 (https=)
JP (1) JPH07110233B2 (https=)
AT (1) ATE62510T1 (https=)
AU (1) AU599329B2 (https=)
CA (1) CA1318616C (https=)
DD (2) DD254212A5 (https=)
DE (1) DE3678647D1 (https=)
DK (1) DK175093B1 (https=)
ES (3) ES2001618A6 (https=)
FI (1) FI91280C (https=)
GB (1) GB8521496D0 (https=)
GR (1) GR862209B (https=)
HU (1) HU211207B (https=)
IE (1) IE58844B1 (https=)
IL (1) IL79837A (https=)
NO (1) NO175871C (https=)
NZ (1) NZ217388A (https=)
PH (1) PH24715A (https=)
PT (1) PT83273B (https=)
SU (1) SU1630616A3 (https=)
ZA (1) ZA866535B (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0245479B1 (en) * 1985-11-13 1993-02-17 Xoma Corporation Shortened phosphoglycerate kinase promoter
MY101203A (en) * 1985-12-12 1991-08-17 Ucp Gen Pharma Ag Production of thrombin iinhibitors.
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
GB8907110D0 (en) * 1988-05-04 1989-05-10 Ciba Geigy Ag Improvements in the production of polypeptides
NO177065C (no) * 1988-09-26 1995-07-12 Labofina Sa Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
EP0548267A4 (en) * 1990-09-04 1994-11-23 Salk Inst Biotech Ind Production of insulin-like growth factor-1 in methylotrophic yeast cells
ATE220105T1 (de) * 1991-04-01 2002-07-15 Merck & Co Inc Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
DE69731960T2 (de) * 1996-09-24 2005-12-15 Cadus Pharmaceutical Corp. Verfahren und zusammensetzungen für die identifizierung von receptor effectoren
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en) 1999-12-10 2005-05-10 The Salk Institute Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
WO2011146833A1 (en) 2010-05-20 2011-11-24 Evolva Inc. Method of producing isoprenoid compounds in yeast
KR20220047395A (ko) 2012-03-09 2022-04-15 베스타론 코포레이션 독성 펩타이드 제조, 식물에서의 펩타이드 발현 및 시스테인 농후 펩타이드의 조합
WO2021216621A2 (en) 2020-04-20 2021-10-28 Vestaron Corporation Proteolytically stable u1-agatoxin-ta1b variant polypeptides for pest control
MX2022013415A (es) 2020-05-01 2022-11-14 Vestaron Corp Combinaciones de insecticidas.
CA3215602A1 (en) 2021-04-01 2022-10-06 Vestaron Corporation Av3 mutant polypeptides for pest control
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method
TW202413392A (zh) 2022-05-18 2024-04-01 美商韋斯塔隆公司 殺蟲ａｃｔｘ肽變異體
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
WO2024026406A2 (en) 2022-07-29 2024-02-01 Vestaron Corporation Next Generation ACTX Peptides
WO2024259306A2 (en) 2023-06-16 2024-12-19 Vestaron Corporation Pvd1 variant polypeptides for pest control
WO2025226701A1 (en) 2024-04-23 2025-10-30 Vestaron Corporation Proteolytically stable u1-agatoxin-ta1b variant polypeptides for pest control

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
IE58011B1 (en) * 1983-05-27 1993-06-16 Texas A & M Univ Sys Method for producing a recombinant baculovirus expression vector
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
PH22337A (en) * 1983-11-21 1988-08-12 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast
DE3587759T2 (de) * 1984-05-11 1994-07-07 Chiron Corp., Emeryville, Calif. Erhöhte Hefetranskription unter Verwendung einer Hybridkonstruktion der Promotorregion.
EP0164566A3 (de) * 1984-05-11 1986-10-29 LGA Gastechnik GmbH Sicherheitseinrichtung für Flüssiggastanks
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen

Also Published As

Publication number Publication date
SU1630616A3 (ru) 1991-02-23
AU6203286A (en) 1987-03-05
HU211207B (en) 1995-11-28
GB8521496D0 (en) 1985-10-02
EP0213593B1 (en) 1991-04-10
AU599329B2 (en) 1990-07-19
JPS6251995A (ja) 1987-03-06
NZ217388A (en) 1989-02-24
GR862209B (en) 1986-12-31
IL79837A (en) 1992-06-21
DE3678647D1 (en) 1991-05-16
JPH07110233B2 (ja) 1995-11-29
US5436136A (en) 1995-07-25
EP0213593A1 (en) 1987-03-11
PT83273A (en) 1986-09-01
NO175871B (https=) 1994-09-12
DK409686D0 (da) 1986-08-28
ATE62510T1 (de) 1991-04-15
IE58844B1 (en) 1993-11-17
PH24715A (en) 1990-10-01
IL79837A0 (en) 1986-11-30
CA1318616C (en) 1993-06-01
PT83273B (pt) 1989-05-12
DD254212A5 (de) 1988-02-17
DD267739A5 (de) 1989-05-10
ES2006383A6 (es) 1989-04-16
FI91280C (fi) 1994-06-10
FI91280B (fi) 1994-02-28
NO863458L (no) 1987-03-02
DK175093B1 (da) 2004-05-24
DK409686A (da) 1987-03-01
FI863430L (fi) 1987-03-01
IE862307L (en) 1987-02-28
ZA866535B (en) 1987-04-29
NO863458D0 (no) 1986-08-28
NO175871C (no) 1994-12-21
FI863430A0 (fi) 1986-08-25
HUT42525A (en) 1987-07-28
ES2006382A6 (es) 1989-04-16

Similar Documents

Publication Publication Date Title
ES2001618A6 (es) Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura.
GB8509817D0 (en) Deoxygenation of aqueous systems
NZ209308A (en) Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein
DK221187D0 (da) Aktiveringsorgan til aerosolventil
DK13780A (da) Koblingslegeme til forseglede roer eller ledninger
DK152382A (da) Faeldningskiselsyrer samt fremgangsmaade til deres fremstilling
NO864786L (no) Sikkerhetsventil.
NO850817L (no) Fremgangsmaate for aa bevare effektiviteten til bakteriepreparater
BR8601686A (pt) Sistema de valvula de alivio de pressao operada por piloto
ES512235A0 (es) Un procedimiento para mejorar la actividad de los catalizadores de oxidos metalicos que contienen teluro.
NO156877B (no) Sikkerhetsventilsystem for en undervannsbroenn.
NO172595C (no) Fremgangsmaate og ekspresjonsplasmid for fremstilling av hemagglutinin under kontroll av drosophila hsp-promoter
DK166100C (da) Kobling til hoejtryksslange
DK43685A (da) Benzobicycliske lactamsyrer og derivater deraf, fremgangsmaade til deres fremstilling samt deres anvendelse
DK388484D0 (da) Chromonalkaloid, fremgangsmaade til isolering deraf fra dysoxylum binectariferum samt dets anvendelse som laegemiddel
NO843267L (no) Brannslukkings-system for helikopterdekk.
DK460885A (da) Sikkerhedsventil til beholdere
NO882614L (no) Anvendelse av jordalkalisater av eterkarboksylsyrer som katalysatorer for alkoksylering.
IT1118622B (it) Procedimento per il recupero su scala industriale di ossido di magnesio di purezza elevata
NO164987C (no) Anvendelse av spermin eller spermidin for beskyttelse av flerumettede fettsyrer mot oksydasjon.
MX148373A (es) Mejoras a sistema de control para la seleccion de una cabina de elevador
DK119082A (da) Phosphor(phosphon)-syreesteramider,fremgangsmaade til fremstilling heraf samt deres anvendelse som midler til bekaempelse afskadelige organismer
IT8619557A0 (it) Analoghi di ammino prostaglandine tiabicicloeptano-sostituite.
DE3585325D1 (de) Umwandlungssystem fuer naturgas.
IT8620163A0 (it) Analoghi di prostaglandine 7-ossabicicloeptano sostituiti.

Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20060830