EP3426258A4 - Kationische steroidale antibiotische zusammensetzungen zur behandlung von hautgewebe - Google Patents

Kationische steroidale antibiotische zusammensetzungen zur behandlung von hautgewebe Download PDF

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Publication number
EP3426258A4
EP3426258A4 EP17764201.4A EP17764201A EP3426258A4 EP 3426258 A4 EP3426258 A4 EP 3426258A4 EP 17764201 A EP17764201 A EP 17764201A EP 3426258 A4 EP3426258 A4 EP 3426258A4
Authority
EP
European Patent Office
Prior art keywords
treatment
dermal tissue
antibiotic compositions
cationic steroidal
steroidal antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP17764201.4A
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English (en)
French (fr)
Other versions
EP3426258A1 (de
Inventor
Paul B. Savage
Carl GENBERG
Ronald Bracken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham Young University
Original Assignee
Brigham Young University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham Young University filed Critical Brigham Young University
Publication of EP3426258A1 publication Critical patent/EP3426258A1/de
Publication of EP3426258A4 publication Critical patent/EP3426258A4/de
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP17764201.4A 2016-03-11 2017-03-10 Kationische steroidale antibiotische zusammensetzungen zur behandlung von hautgewebe Pending EP3426258A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662306810P 2016-03-11 2016-03-11
US201662412079P 2016-10-24 2016-10-24
US15/454,135 US10226550B2 (en) 2016-03-11 2017-03-09 Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
PCT/US2017/021832 WO2017156418A1 (en) 2016-03-11 2017-03-10 Cationic steroidal antibiotic compositions for the treatment of dermal tissue

Publications (2)

Publication Number Publication Date
EP3426258A1 EP3426258A1 (de) 2019-01-16
EP3426258A4 true EP3426258A4 (de) 2019-11-13

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ID=59788397

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17764201.4A Pending EP3426258A4 (de) 2016-03-11 2017-03-10 Kationische steroidale antibiotische zusammensetzungen zur behandlung von hautgewebe

Country Status (4)

Country Link
US (2) US10226550B2 (de)
EP (1) EP3426258A4 (de)
KR (2) KR102598106B1 (de)
WO (1) WO2017156418A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
WO2013013223A1 (en) 2011-07-20 2013-01-24 Brigham Young University Hydrogel materials incorporating eluting ceragenin compound
CA3152410A1 (en) 2011-10-14 2013-04-18 Sage Therapeutics, Inc. 3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders
CA2897150C (en) 2013-01-07 2021-07-13 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
AU2014234992B2 (en) 2013-03-15 2018-01-18 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
CN112110976B (zh) 2013-04-17 2023-08-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
CN113527400A (zh) 2013-04-17 2021-10-22 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
LT3021852T (lt) 2013-07-19 2021-04-12 Sage Therapeutics, Inc. Neuroaktyvūs steroidai, jų kompozicijos ir panaudojimas
DK3488852T3 (da) 2013-08-23 2021-02-01 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser deraf
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
ES2808855T3 (es) 2014-10-16 2021-03-02 Sage Therapeutics Inc Composiciones y métodos para tratar trastornos del SNC
TW202235090A (zh) 2014-10-16 2022-09-16 美商賽吉醫療公司 用於治療中樞神經系統(cns)病症之組合物及方法
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
HUE054092T2 (hu) 2015-01-26 2021-08-30 Sage Therapeutics Inc Központi idegrendszeri zavarok kezelésére szolgáló kompozíciók és eljárások
ES2935476T3 (es) 2015-02-20 2023-03-07 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
CA3030420A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C20, C17 and C21 converted neuroactive steroids and methods of using them
CN115974954A (zh) 2016-08-23 2023-04-18 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇的晶体
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
US20210361672A1 (en) * 2018-03-07 2021-11-25 Brigham Young University Method of Treating Ciliated Tissue Using CSA Micelles
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
WO2020210440A1 (en) 2019-04-12 2020-10-15 Geltor, Inc. Recombinant elastin and production thereof
BR112021024033A2 (pt) 2019-05-31 2022-02-08 Sage Therapeutics Inc Esteroides neuroativos e suas composições
GB2610313A (en) 2020-01-24 2023-03-01 Geltor Inc Animal-free dietary collagen
WO2023105494A1 (en) 2021-12-10 2023-06-15 Universidade Do Porto Cationic steroid compounds, method of obtaining thereof, formulations comprising thereof and their uses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110135742A1 (en) * 2006-06-20 2011-06-09 The Regents Of The University Of California Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles
US20140336131A1 (en) * 2013-03-15 2014-11-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US20150203257A1 (en) * 2008-07-07 2015-07-23 Grc Pack Luxembourg S.A. Flexible container for packaging, in particular in sterile conditions, of food products and relative package comprising said flexible container

Family Cites Families (190)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US821187A (en) 1906-05-22 peters
DE1037074B (de) 1957-03-25 1958-08-21 Schering Ag Mundpflegemittel
US3843779A (en) 1971-03-22 1974-10-22 Colgate Palmolive Co Process for preparing stable dentifrice
US4284236A (en) 1978-05-17 1981-08-18 Carrier Drysys Limited Air conditioning system
US4248236A (en) 1978-12-26 1981-02-03 Linder Gerald S Packaged medical appliance
US4473988A (en) 1979-10-24 1984-10-02 Colgate-Palmolive Company Dentifrice packaging process
US4296206A (en) 1980-04-30 1981-10-20 United States Of America Irreversible anti-glucocorticoids
US4289755A (en) 1980-11-03 1981-09-15 Richardson-Vicks Inc. Stable mouthwash compositions containing zinc and fluoride compounds
JPS6080457A (ja) 1983-10-07 1985-05-08 ユニチカ株式会社 抗菌剤徐放性導尿カテ−テル
FR2558107B3 (fr) 1984-01-12 1987-03-20 Dechaume Geoffroy Materiau sandwich a ondulations interieures de papier et protection exterieure par pellicule plastique et procedes de realisation d'un tel materiau
US4661341A (en) 1984-10-30 1987-04-28 The Procter & Gamble Company Oral compositions
US4723950A (en) 1984-12-12 1988-02-09 C. R. Bard, Inc. Urine drainage bag outlet with barrier against microbial infection
US5506354A (en) 1985-09-12 1996-04-09 The Upjohn Company Imidazolylpiperazinyl steroids
US4842593A (en) 1987-10-09 1989-06-27 The Procter & Gamble Company Disposable absorbent articles for incontinent individuals
US4865855A (en) 1988-01-11 1989-09-12 Kimberly-Clark Corporation Antimicrobial absorbent food pad
US4990338A (en) 1988-05-09 1991-02-05 Dow Corning Corporation Antimicrobial superabsorbent compositions and methods
US5356630A (en) 1989-02-22 1994-10-18 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
US4972848A (en) 1989-08-23 1990-11-27 Medtronic, Inc. Medical electrical lead with polymeric monolithic controlled release device and method of manufacture
US5025754A (en) 1990-02-01 1991-06-25 David Plyler Apparatus and method for providing drinking water to poultry
JPH0474026A (ja) 1990-07-16 1992-03-09 Nippon Telegr & Teleph Corp <Ntt> 移動通信における接続制御方法
GB9020075D0 (en) 1990-09-14 1990-10-24 Filler Aaron G Contrast agents for magnetic resonance imaging of axonal transport
US5310545A (en) 1991-04-11 1994-05-10 Drore Eisen Method of treatment using mouthwashes containing steroids and antifungal agents and compositions of matter
US5286479A (en) 1991-12-10 1994-02-15 The Dow Chemical Company Oral compositions for suppressing mouth odors
EP0608433B1 (de) * 1992-07-13 2004-05-19 Shiseido Company, Ltd. Dermatologische zusammensetzung
US5234703A (en) 1992-10-31 1993-08-10 Guthery B Eugene Disinfecting product and process
JP2877636B2 (ja) 1992-11-18 1999-03-31 積水化成品工業株式会社 抗菌性ドリップシート
US5352682A (en) 1993-03-08 1994-10-04 Digestive Care Inc. Compositions containing salts of bile acid-aminosalicylate conjugates
KR100296810B1 (ko) 1993-03-12 2001-10-24 로렌스 티. 마이젠헬더 결정성세프티오퍼유리산
US5407573A (en) 1993-06-01 1995-04-18 Alpine Water Purification, Inc. Continuous flow water-purifying device
PT749437E (pt) 1994-03-10 2002-03-28 Magainin Pharma Utilizacoes farmaceuticas de derivados de esteroides
US5856535A (en) 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US20020091433A1 (en) 1995-04-19 2002-07-11 Ni Ding Drug release coated stent
US5624704A (en) 1995-04-24 1997-04-29 Baylor College Of Medicine Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent
US5763430A (en) 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5687714A (en) 1995-10-10 1997-11-18 The United States Of America As Represented By The Department Of Health And Human Services Self-cleaning endotracheal tube apparatus
JP3044367B2 (ja) 1995-11-13 2000-05-22 三洋化成工業株式会社 抗菌性吸水剤組成物およびその製法
US6132765A (en) 1996-04-12 2000-10-17 Uroteq Inc. Drug delivery via therapeutic hydrogels
GB9608483D0 (en) 1996-04-25 1996-07-03 Smiths Industries Plc Introducers and assemblies
WO1998005337A1 (en) 1996-08-01 1998-02-12 Cocensys, Inc. Use of gaba and nmda receptor ligands for the treatment of migraine headache
WO1998019713A1 (en) 1996-11-06 1998-05-14 Sts Biopolymers Inc. Echogenic coating containing gaseous spaces for ultrasonography
US5897770A (en) 1997-10-23 1999-04-27 Plymouth Products, Inc. Center core cartridge feeder insert
US20040170563A1 (en) 1997-10-27 2004-09-02 Meade Thomas J. Magnetic resonance imaging agents for the delivery of therapeutic agents
US6767904B2 (en) 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
GB9804861D0 (en) 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
US6350738B1 (en) 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
DE69824638T2 (de) 1998-03-06 2005-06-23 Brigham Young University, Provo Antibiotische steroidderivate
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US7820734B2 (en) 1998-10-07 2010-10-26 Tyco Healthcare Group Lp Antimicrobial lubricious coating
US6329488B1 (en) 1998-11-10 2001-12-11 C. R. Bard, Inc. Silane copolymer coatings
US6667299B1 (en) 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
NO307168B1 (no) 1999-03-01 2000-02-21 Orix As Oralt preparat som er effektivt mot halitose
US6217896B1 (en) 1999-04-01 2001-04-17 Uab Research Foundation Conjunctival inserts for topical delivery of medication or lubrication
US6673771B1 (en) 1999-07-28 2004-01-06 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclast activity
WO2001014406A1 (fr) 1999-08-23 2001-03-01 Chugai Seiyaku Kabushiki Kaisha Agents anti-androgènes
US7074778B2 (en) 1999-12-09 2006-07-11 Genaera Corporation Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
IT1317862B1 (it) 2000-02-29 2003-07-15 Bracco Spa Coniugati di acidi biliari con chelati complessi di ioni metallici eloro uso.
US6551608B2 (en) 2000-03-06 2003-04-22 Porex Technologies Corporation Porous plastic media with antiviral or antimicrobial properties and processes for making the same
WO2001076650A1 (en) * 2000-04-06 2001-10-18 University Technology Corporation Compositions and methods for promoting wound healing
JP5052730B2 (ja) 2000-08-15 2012-10-17 ブリガム ヤング ユニバーシティ ステロイド由来抗生物質
JP3435405B2 (ja) 2000-11-24 2003-08-11 株式会社ティーセル研究所 家畜の乳房炎治療剤及びこれを用いた乳房炎の治療方法
US6514556B2 (en) 2000-12-15 2003-02-04 Ecolab Inc. Method and composition for washing poultry during processing
US6803066B2 (en) 2001-01-18 2004-10-12 Praxair Technology, Inc. Sanitizing food products
JP4674980B2 (ja) 2001-02-26 2011-04-20 サンスター株式会社 アルコール無配合液体口腔用組成物
MXPA03007672A (es) 2001-02-26 2004-11-12 Univ Sydney Metodo para mejorar la funcion de crecimiento de un animal.
ES2189649B1 (es) 2001-06-15 2004-09-16 Oftrai S.L. Nueva composicion desinfectante y antiseptica.
US6921390B2 (en) 2001-07-23 2005-07-26 Boston Scientific Scimed, Inc. Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface
JP5170934B2 (ja) 2001-08-16 2013-03-27 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 改良dnaリポフェクションならびに/または徐放性プロドラッグおよび薬物療法のための試薬の合成と使用
US9056048B2 (en) 2001-08-16 2015-06-16 The Trustees Of The University Of Pennsylvania Synthesis and use of cationic steroids for anti-inflammatory drug therapy
US6939376B2 (en) 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US6887270B2 (en) 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US7048956B2 (en) 2002-03-05 2006-05-23 The Penn State Research Foundation Process for antimicrobial treatment of fresh produce, particularly mushrooms
DE10218147B4 (de) 2002-04-23 2005-12-22 Stockhausen Gmbh Wasserabsorbierende, die Zersetzung von Körperflüssigkeiten verzögernde Polymerteilchen, deren Herstellung und Verwendung
US7334580B2 (en) 2002-05-07 2008-02-26 Smaldone Gerald C Methods, devices and formulations for targeted endobronchial therapy
DE10228104A1 (de) 2002-06-24 2004-01-15 Bayer Cropscience Ag Fungizide Wirkstoffkombination
US6689342B1 (en) 2002-07-29 2004-02-10 Warner-Lambert Company Oral care compositions comprising tropolone compounds and essential oils and methods of using the same
JP2006503839A (ja) 2002-09-23 2006-02-02 シェーリング コーポレイション 真菌感染の処置のためのポサコナゾールの使用
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7659061B2 (en) 2002-11-19 2010-02-09 Pharmacia & Upjohn Company Pharmaceutical compositions having a modified vehicle
US7282214B2 (en) 2002-12-19 2007-10-16 Johnson & Johnson Vision Care, Inc. Biomedical devices with antimicrobial coatings
US8420050B2 (en) 2003-01-13 2013-04-16 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7226577B2 (en) 2003-01-13 2007-06-05 Bracco Imaging, S. P. A. Gastrin releasing peptide compounds
US7611692B2 (en) 2003-01-13 2009-11-03 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US7850947B2 (en) 2003-01-13 2010-12-14 Bracco Imaging S.P.A. Gastrin releasing peptide compounds
US6928893B2 (en) 2003-01-15 2005-08-16 General Motors Corporation Method of making a gas diffusion media and quality controls for same
JP2006520779A (ja) 2003-03-20 2006-09-14 ファルマシア コーポレイション 抗炎症薬の分散性処方物
DE10317931A1 (de) 2003-04-17 2004-11-11 Schülke & Mayr GmbH Chemothermisches Desinfektionsverfahren
US6872306B2 (en) 2003-04-22 2005-03-29 Albert Shen Multifunctional pure water maker
DE10328261B4 (de) 2003-06-23 2007-10-25 Beiersdorf Ag Desinfizierende Auflage mit Silberbeschichtung und ihre Verwendung
NZ543643A (en) 2003-06-23 2007-09-28 Beiersdorf Ag Antimicrobial wound dressing with two layers and antimicrobial metal between layers but not on exterior
WO2005007209A1 (en) 2003-07-17 2005-01-27 Bioretec Oy Synthetic, bioabsorbable polymer materials and implants
CN100418585C (zh) 2003-07-24 2008-09-17 伯拉考成像股份公司 稳定的放射性药物组合物及制备方法
GB0318901D0 (en) 2003-08-12 2003-09-17 Univ Bath Improvements in or relating to bone substitute material
US6872303B2 (en) 2003-08-12 2005-03-29 Ian M. Knapp Water treatment cartridge
US20050267051A1 (en) 2003-12-19 2005-12-01 Lee Henry J Antineoplastic and anti-HIV conjugates of steroid acid and nucleosides
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US20060062774A1 (en) 2004-09-21 2006-03-23 The Procter & Gamble Company Compositions for maintaining and restoring normal urogenital flora
US20100092398A1 (en) 2004-09-30 2010-04-15 Max Reynolds Antimicrobial compositions and applications therefore
JP5022368B2 (ja) 2005-08-26 2012-09-12 ベクトン・ディキンソン・アンド・カンパニー エラストマー性封止物品の滅菌方法
EP1923065B1 (de) 2005-09-08 2010-12-01 Kabushiki Kaisha Yakult Honsha Cholesterol-absorptionsinhibitor
ES2661728T3 (es) * 2005-10-03 2018-04-03 Pinksky, Mark A. Composiciones y métodos para el cuidado mejorado de la piel
US20100226884A1 (en) 2009-01-20 2010-09-09 Immunomedics, Inc. Novel Class of Monospecific and Bispecific Humanized Antibodies that Target the Insulin-like Growth Factor Type I Receptor (IGF-1R)
TW200729539A (en) 2006-01-26 2007-08-01 Litmx Inc Making method for the circuit board of separated light emitting diode
WO2007089903A2 (en) 2006-02-01 2007-08-09 Brigham Young University Cationic steroid microbial compositions for treating or preventing influenza infections
WO2008048340A2 (en) 2006-02-01 2008-04-24 Brigham Young University Cationic steroid antimicrobial compositions for treating poxvirus infections
AU2007211279B2 (en) 2006-02-01 2013-02-14 Brigham Young University Cationic steroid antimicrobial compositions and methods of use
WO2007089906A2 (en) 2006-02-01 2007-08-09 Brigham Young University Cationic steroid antimicrobial compositions for treating or preventing herpes infections
JP4366507B2 (ja) 2006-03-20 2009-11-18 国立大学法人北陸先端科学技術大学院大学 酸化蛋白質の定量方法
DE102006016060B4 (de) 2006-04-04 2012-10-25 Zf Friedrichshafen Ag Radialgelenk und Verfahren zur Herstellung eines derartigen Radialgelenkes für ein Kraftfahrzeug
US7741273B2 (en) 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
WO2007134176A2 (en) 2006-05-10 2007-11-22 Microban Products Company Antimicrobial food pad
US7858000B2 (en) 2006-06-08 2010-12-28 Novartis Ag Method of making silicone hydrogel contact lenses
WO2008006083A2 (en) 2006-07-07 2008-01-10 Surmodics, Inc. Beaded wound spacer device
US20100022481A1 (en) 2006-08-02 2010-01-28 Dong Wang Drug Carriers, Their Synthesis, and Methods of Use Thereof
KR100950204B1 (ko) 2006-09-26 2010-03-29 경북대학교 산학협력단 7α-아미노스테로이드 유도체 또는 이의 약학적으로허용가능한 염, 이의 제조방법 및 이를 유효성분으로함유하는 항암용 또는 항생제 조성물
US9186511B2 (en) 2006-10-13 2015-11-17 Cyberonics, Inc. Obstructive sleep apnea treatment devices, systems and methods
KR101454041B1 (ko) 2006-11-06 2014-10-27 노파르티스 아게 안구 장치 및 그의 제조 및 사용 방법
US8784893B2 (en) * 2007-02-05 2014-07-22 Carbylan Therapeutics, Inc. Polymer formulations for delivery of bioactive agents
MX2009008364A (es) 2007-02-07 2009-08-20 Astrazeneca Ab Sal de napadisilato de un antagonista m3 muscarinico.
US7854941B2 (en) 2007-02-12 2010-12-21 The University Of Southern Mississippi Method of attaching drug compounds to non-reactive polymer surfaces
JP2008311504A (ja) 2007-06-15 2008-12-25 Toshiba Corp 半導体集積回路
US20090016973A1 (en) 2007-07-09 2009-01-15 Micropure, Inc. Composition and Method for the Prevention of Oral Disease
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8558051B2 (en) 2007-07-18 2013-10-15 The Procter & Gamble Company Disposable absorbent article having odor control system
US8772220B2 (en) 2007-08-24 2014-07-08 Sekisui Specialty Chemicals America, Llc Chemical delivery product and process for making the same
US20090068122A1 (en) 2007-09-06 2009-03-12 Shira Pilch Dentifrice Compositions for Treating Xerostomia
US9095568B2 (en) 2007-09-26 2015-08-04 Mark Berninger Therapeutic and vaccine polyelectrolyte nanoparticle compositions
US20090099531A1 (en) 2007-10-15 2009-04-16 Griesbach Iii Henry Louis Packaging for selectivity lubricating part of a medical device
AU2008314505C1 (en) 2007-10-16 2020-11-05 Progen Pg500 Series Pty Ltd Novel sulfated oligosaccharide derivatives
GB0724278D0 (en) 2007-12-13 2008-01-30 Syntopix Ltd uses for antimicrobial agents
WO2009144708A1 (en) * 2008-04-14 2009-12-03 Ganot, Arie Augmentation and treatment of gingival defects
US9943614B2 (en) 2008-06-17 2018-04-17 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
US20090324517A1 (en) 2008-06-30 2009-12-31 Dan Kline Halitosis treatment
KR20110028372A (ko) 2008-07-09 2011-03-17 보드 오브 리젠츠 오브 디 유니버시티 오브 네브라스카 화학 물질의 경조직 표적화 전달을 위한 기능성 마이셀
JP5147814B2 (ja) 2009-11-12 2013-02-20 ブリガム・ヤング・ユニバーシティ ステロイド由来抗生物質
US8623416B2 (en) 2009-11-25 2014-01-07 Michael Zasloff Formulations comprising aminosterols
US8529681B1 (en) 2010-01-07 2013-09-10 Sandia Corporation Biofouling-resistant ceragenin-modified materials and structures for water treatment
AU2011222612A1 (en) 2010-03-04 2012-09-20 The Trustees Of The University Of Pennsylvania Center For Technology Transfer Antimicrobial cationic stereoids and methods of use
JP5720103B2 (ja) 2010-03-18 2015-05-20 東レ株式会社 シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ
KR101134342B1 (ko) 2010-04-22 2012-04-09 주식회사 메가젠임플란트 치과용 임플란트의 픽스츄어 및 그를 구비하는 임플란트 시술용 세트
US8815228B2 (en) 2010-04-30 2014-08-26 Ayman Boutros Alloplastic injectable dermal filler and methods of use thereof
US8968783B2 (en) * 2010-05-27 2015-03-03 Covidien Lp Hydrogel implants with varying degrees of crosslinking
US8871716B2 (en) 2010-10-08 2014-10-28 Korea Advanced Institute Of Science And Technology Use of antimicrobial peptides in regeneration of skin cells
RU2576459C2 (ru) 2010-11-03 2016-03-10 Брайем Янг Юниверсити Устойчивые при хранении антимикробные композиции, включающие церагениновые соединения, и способы их применения
GB201021937D0 (en) 2010-12-24 2011-02-02 Reckitt & Colman Overseas Skin sanitizer compositions comprising alcohol based emulsion
CN102172356B (zh) 2011-03-03 2013-04-03 山东农业大学 牛磺鹅去氧胆酸在制备防治骨质疏松的药物中的应用
US20130004586A1 (en) 2011-06-24 2013-01-03 Vachon David J Biologically Efficacious Compositions, Articles of Manufacture and Processes for Producing and/or Using Same
US8810380B2 (en) 2011-07-01 2014-08-19 Gerald F. Leitz Golf scoring management system
WO2013013223A1 (en) 2011-07-20 2013-01-24 Brigham Young University Hydrogel materials incorporating eluting ceragenin compound
WO2013029055A1 (en) 2011-08-25 2013-02-28 Brigham Young University Incorporation of particulate ceragenins in polymers
US8945217B2 (en) 2011-08-25 2015-02-03 Brigham Young University Medical devices incorporating ceragenin-containing composites
WO2013029059A1 (en) * 2011-08-25 2013-02-28 Brigham Young University Medical devices incorporating ceragenin-containing composites
JP6038155B2 (ja) 2011-09-13 2016-12-07 ブリガム・ヤング・ユニバーシティBrigham Young University 組織創傷を治癒させる製品
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
JP6038154B2 (ja) 2011-09-13 2016-12-07 ブリガム・ヤング・ユニバーシティBrigham Young University 骨疾患および破断骨治療のための組成物
CN103974691A (zh) 2011-12-15 2014-08-06 高露洁-棕榄公司 水性口腔护理组合物
WO2013109236A2 (en) 2011-12-21 2013-07-25 Colgate-Palmolive Company Oral care compositions
US20140363780A1 (en) 2011-12-21 2014-12-11 Brigham Young University Oral care compositions
EP2819531B1 (de) 2012-03-01 2016-01-20 Brigham Young University Antimikrobielle lebensmittelverarbeitungszusammensetzungen mit cerageninverbindungen und verfahren zur verwendung
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
JP5803795B2 (ja) 2012-04-20 2015-11-04 富士通株式会社 受信装置、周波数偏差算出方法及びコンピュータプログラム
US20130280391A1 (en) 2012-04-24 2013-10-24 Brigham Young University Anti-microbial wash compositions including ceragenin compounds and methods of use for treating non-meat food products
US10039285B2 (en) 2012-05-02 2018-08-07 Brigham Young University Ceragenin particulate materials and methods for making same
AU2013257951A1 (en) 2012-05-11 2015-01-22 Akron Molecules Ag Use of compounds for the treatment of pain
KR20140029864A (ko) 2012-08-30 2014-03-11 삼성디스플레이 주식회사 표시 장치 및 이를 이용한 에어 터치 인식 방법 및 이를 이용한 입체 영상 표시 방법
BR112015008804A2 (pt) 2012-10-17 2017-07-04 Univ Brigham Young tratamento e prevenção de mastite
KR20230078823A (ko) 2012-12-13 2023-06-02 이뮤노메딕스, 인코오포레이티드 개선된 효능 및 감소된 독성을 위한 항체 및 sn-38의 면역컨쥬게이트의 투약
CA2897150C (en) 2013-01-07 2021-07-13 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
AU2014234992B2 (en) 2013-03-15 2018-01-18 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) * 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
US9527883B2 (en) 2015-04-22 2016-12-27 Brigham Young University Methods for the synthesis of ceragenins
WO2016172534A1 (en) 2015-04-22 2016-10-27 Savage Paul B Cationic steroidal antimicrobial salts
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
US20170080128A1 (en) 2015-09-21 2017-03-23 Brigham Young University Novel endotracheal tube for the reduction of intubation-related complication in neonates and babies
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
US20180206726A1 (en) 2016-12-07 2018-07-26 Progenity Inc. Gastrointestinal tract detection methods, devices and systems

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110135742A1 (en) * 2006-06-20 2011-06-09 The Regents Of The University Of California Controlled release encapsulated anti-bacterial and anti-inflammatory nanoparticles
US20150203257A1 (en) * 2008-07-07 2015-07-23 Grc Pack Luxembourg S.A. Flexible container for packaging, in particular in sterile conditions, of food products and relative package comprising said flexible container
US20140336131A1 (en) * 2013-03-15 2014-11-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2017156418A1 *

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US20170258963A1 (en) 2017-09-14
KR20180121615A (ko) 2018-11-07
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US11253634B2 (en) 2022-02-22
KR20220051277A (ko) 2022-04-26
EP3426258A1 (de) 2019-01-16
KR102598106B1 (ko) 2023-11-03
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