EP3332814A4 - Structure de cellule, animal modèle non-humain, procédé de production d'animal modèle non-humain, et procédé d'évaluation d'une substance d'essai - Google Patents
Structure de cellule, animal modèle non-humain, procédé de production d'animal modèle non-humain, et procédé d'évaluation d'une substance d'essai Download PDFInfo
- Publication number
- EP3332814A4 EP3332814A4 EP16832892.0A EP16832892A EP3332814A4 EP 3332814 A4 EP3332814 A4 EP 3332814A4 EP 16832892 A EP16832892 A EP 16832892A EP 3332814 A4 EP3332814 A4 EP 3332814A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- model animal
- human model
- cell structure
- test substance
- evaluating test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241001465754 Metazoa Species 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
- A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/12—Animals modified by administration of exogenous cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/15—Humanized animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2207/00—Modified animals
- A01K2207/30—Animals modified by surgical methods
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Environmental Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Transplantation (AREA)
- General Engineering & Computer Science (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015153298 | 2015-08-03 | ||
PCT/JP2016/072137 WO2017022613A1 (fr) | 2015-08-03 | 2016-07-28 | Structure de cellule, animal modèle non-humain, procédé de production d'animal modèle non-humain, et procédé d'évaluation d'une substance d'essai |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3332814A1 EP3332814A1 (fr) | 2018-06-13 |
EP3332814A4 true EP3332814A4 (fr) | 2018-07-25 |
Family
ID=57942937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16832892.0A Pending EP3332814A4 (fr) | 2015-08-03 | 2016-07-28 | Structure de cellule, animal modèle non-humain, procédé de production d'animal modèle non-humain, et procédé d'évaluation d'une substance d'essai |
Country Status (5)
Country | Link |
---|---|
US (1) | US20180171324A1 (fr) |
EP (1) | EP3332814A4 (fr) |
JP (2) | JP6710211B2 (fr) |
CN (1) | CN107921173B (fr) |
WO (1) | WO2017022613A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2743220C1 (ru) * | 2020-07-14 | 2021-02-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации | Способ индивидуальной оценки биосовместимости с организмом имплантируемых полимерных материалов |
JPWO2023042875A1 (fr) * | 2021-09-16 | 2023-03-23 |
Citations (6)
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WO2007138098A2 (fr) * | 2006-05-31 | 2007-12-06 | Projech Science To Technology, S.L. | Modèles animaliers de métastases tumorales et toxicité |
WO2011108517A1 (fr) * | 2010-03-01 | 2011-09-09 | 富士フイルム株式会社 | Structure cellulaire comportant des cellules et des blocs macromoléculaires ayant une biocompatibilité |
EP2564880A1 (fr) * | 2011-08-31 | 2013-03-06 | Fujifilm Corporation | Construction de cellules pour la transplantation cellulaire et agrégat de cellules pour transplantation cellulaire |
WO2014133081A1 (fr) * | 2013-02-27 | 2014-09-04 | 富士フイルム株式会社 | Structure cellulaire pour transplantation cellulaire, bloc de polymère biocompatible et procédés pour les produire |
WO2016052504A1 (fr) * | 2014-09-30 | 2016-04-07 | 富士フイルム株式会社 | Composition, structure cellulaire, kit de transplantation d'îlot, agent thérapeutique de transplantation de cellule d'îlot de langerhans, et agent de réduction de glycémie, composition comprenant des îlots, kit comprenant des îlots, et agent thérapeutique de transplantation d'îlot, et agent de réduction de glycémie |
WO2017010414A1 (fr) * | 2015-07-10 | 2017-01-19 | 富士フイルム株式会社 | Structure cellulaire et procédé permettant de produire une structure cellulaire |
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US5032508A (en) * | 1988-09-08 | 1991-07-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
WO1999019479A1 (fr) * | 1997-09-26 | 1999-04-22 | Corixa Corporation | Modele murin associe a un carcinome humain |
EP1507454A4 (fr) * | 2002-05-30 | 2007-11-21 | Raven Biotechnologies Inc | Modele animal permettant de predire la toxicologie et le dosage |
EP1857543B1 (fr) * | 2005-02-15 | 2012-04-04 | School Juridical Person Kitasato Gakuen | Procédé et appareil pour à produire un tissu de culture de densité élevée |
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2016
- 2016-07-28 JP JP2017532538A patent/JP6710211B2/ja active Active
- 2016-07-28 CN CN201680045485.3A patent/CN107921173B/zh active Active
- 2016-07-28 EP EP16832892.0A patent/EP3332814A4/fr active Pending
- 2016-07-28 WO PCT/JP2016/072137 patent/WO2017022613A1/fr active Application Filing
-
2018
- 2018-02-02 US US15/887,083 patent/US20180171324A1/en active Pending
-
2020
- 2020-05-26 JP JP2020091250A patent/JP2020124226A/ja active Pending
Patent Citations (12)
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WO2007138098A2 (fr) * | 2006-05-31 | 2007-12-06 | Projech Science To Technology, S.L. | Modèles animaliers de métastases tumorales et toxicité |
WO2011108517A1 (fr) * | 2010-03-01 | 2011-09-09 | 富士フイルム株式会社 | Structure cellulaire comportant des cellules et des blocs macromoléculaires ayant une biocompatibilité |
EP2543397A1 (fr) * | 2010-03-01 | 2013-01-09 | FUJIFILM Corporation | Structure cellulaire comportant des cellules et des blocs macromoléculaires ayant une biocompatibilité |
EP2564880A1 (fr) * | 2011-08-31 | 2013-03-06 | Fujifilm Corporation | Construction de cellules pour la transplantation cellulaire et agrégat de cellules pour transplantation cellulaire |
JP2014012114A (ja) * | 2011-08-31 | 2014-01-23 | Fujifilm Corp | 細胞移植用細胞構造体および細胞移植用細胞集合体 |
WO2014133081A1 (fr) * | 2013-02-27 | 2014-09-04 | 富士フイルム株式会社 | Structure cellulaire pour transplantation cellulaire, bloc de polymère biocompatible et procédés pour les produire |
EP2962703A1 (fr) * | 2013-02-27 | 2016-01-06 | Fujifilm Corporation | Structure cellulaire pour transplantation cellulaire, bloc de polymère biocompatible et procédés pour les produire |
WO2016052504A1 (fr) * | 2014-09-30 | 2016-04-07 | 富士フイルム株式会社 | Composition, structure cellulaire, kit de transplantation d'îlot, agent thérapeutique de transplantation de cellule d'îlot de langerhans, et agent de réduction de glycémie, composition comprenant des îlots, kit comprenant des îlots, et agent thérapeutique de transplantation d'îlot, et agent de réduction de glycémie |
EP3202409A1 (fr) * | 2014-09-30 | 2017-08-09 | Fujifilm Corporation | Composition, structure cellulaire, kit de transplantation d'îlot, agent thérapeutique de transplantation de cellule d'îlot de langerhans, et agent de réduction de glycémie, composition comprenant des îlots, kit comprenant des îlots, et agent thérapeutique de transplantation d'îlot, et agent de réduction de glycémie |
WO2017010414A1 (fr) * | 2015-07-10 | 2017-01-19 | 富士フイルム株式会社 | Structure cellulaire et procédé permettant de produire une structure cellulaire |
EP3320925A1 (fr) * | 2015-07-10 | 2018-05-16 | Fujifilm Corporation | Structure cellulaire et procédé permettant de produire une structure cellulaire |
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Non-Patent Citations (9)
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BOJ SYLVIA F ET AL: "Organoid Models of Human and Mouse Ductal Pancreatic Cancer", CELL, CELL PRESS, AMSTERDAM, NL, vol. 160, no. 1, 31 December 2014 (2014-12-31), pages 324 - 338, XP029132656, ISSN: 0092-8674, DOI: 10.1016/J.CELL.2014.12.021 * |
CLAUS KORDES ET AL: "Stellate cells are mesenchymal stem cells", EUROPEAN JOURNAL OF MEDICAL RESEARCH, BIOMED CENTRAL LTD, LONDON, UK, vol. 19, no. Suppl 1, 19 June 2014 (2014-06-19), pages S6, XP021189787, ISSN: 2047-783X, DOI: 10.1186/2047-783X-19-S1-S6 * |
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KENNETH P: OLIVE ET AL: "Supplementary Online Materials", 21 May 2009 (2009-05-21), XP055484705, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998180/bin/NIHMS228663-supplement-Supplementary_Materials.pdf> [retrieved on 20180615] * |
LEI DAI ET AL: "Construction of orthotopic xenograft mouse models for human pancreatic cancer", EXPERIMENTAL AND THERAPEUTIC MEDICINE, vol. 10, no. 3, 16 July 2015 (2015-07-16), GR, pages 1033 - 1038, XP055484815, ISSN: 1792-0981, DOI: 10.3892/etm.2015.2642 * |
See also references of WO2017022613A1 * |
STACEY J COLEMAN: "Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 20, no. 26, 14 July 2014 (2014-07-14), CN, pages 8471, XP055484833, ISSN: 1007-9327, DOI: 10.3748/wjg.v20.i26.8471 * |
VISWANATH DAS ET AL: "Pathophysiologically relevant in vitro tumor models for drug screening", DRUG DISCOVERY TODAY, vol. 20, no. 7, 20 April 2015 (2015-04-20), AMSTERDAM, NL, pages 848 - 855, XP055484827, ISSN: 1359-6446, DOI: 10.1016/j.drudis.2015.04.004 * |
Also Published As
Publication number | Publication date |
---|---|
EP3332814A1 (fr) | 2018-06-13 |
WO2017022613A1 (fr) | 2017-02-09 |
US20180171324A1 (en) | 2018-06-21 |
CN107921173A (zh) | 2018-04-17 |
JP6710211B2 (ja) | 2020-06-17 |
JP2020124226A (ja) | 2020-08-20 |
CN107921173B (zh) | 2021-07-06 |
JPWO2017022613A1 (ja) | 2018-07-12 |
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