EP3325354B1 - Procédé et dispositif de séparation et de transfert de pastilles - Google Patents

Procédé et dispositif de séparation et de transfert de pastilles Download PDF

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Publication number
EP3325354B1
EP3325354B1 EP15739179.8A EP15739179A EP3325354B1 EP 3325354 B1 EP3325354 B1 EP 3325354B1 EP 15739179 A EP15739179 A EP 15739179A EP 3325354 B1 EP3325354 B1 EP 3325354B1
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EP
European Patent Office
Prior art keywords
passage
pellets
pellet
channel
pressure differential
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EP15739179.8A
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German (de)
English (en)
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EP3325354A1 (fr
Inventor
Achim Wolf
Stefan Wolf
Karlheinz Seyfang
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Harro Hofliger Verpackungsmaschinen GmbH
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Harro Hofliger Verpackungsmaschinen GmbH
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B37/00—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
    • B65B37/16—Separating measured quantities from supply
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B37/00—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
    • B65B37/14—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged by pneumatic feeders

Definitions

  • the invention relates to a method for delimiting and transferring pellets, in particular cryopellets, into a target container, as well as to a separating device for carrying out this method.
  • active pharmaceutical ingredients are applied as a solution, but are unstable in dissolved form. As a freeze-dried formulation, however, they can be stably stored and reconstituted immediately before use. Examples include biotechnological products, peptides, vaccines and certain reagents.
  • cryopellets are also produced in the form of more or less spherical multiparticulate preparations as so-called cryopellets.
  • the starting solution is brought into drop form, wherein drops can be produced with a precisely defined volume.
  • these drops are frozen in liquid nitrogen and then dried by sublimation.
  • the dry cryopellets produced in this way have at least approximately a spherical shape with a defined mean diameter. If necessary, they can be brought back into solution in a suitable amount. It is desirable to produce only such a limited amount of solution as is necessary to meet the immediate needs, for which appropriate amounts of Cryopellets are kept in appropriate packaging units.
  • a metering device and a method for metering dry urea pellets are known.
  • a supply of pellets is provided in a storage room.
  • the pellets are directed from the storage space into two downwardly leading and upwardly oriented metering channels in such a way that in each case a column of superimposed pellets forms in both metering channels.
  • the lowest pellet of such a column is located in each case in a connection point, in which engages a slide element with two receiving spaces.
  • the two receiving chambers are alternately filled and emptied one at a time into a discharge channel running parallel downwards.
  • Sensitive pellets can be mechanically damaged by the slider element and its shearing motion.
  • the invention is therefore based on the object of specifying a method for the delimitation and the transfer of pellets in a target container, which allows a reliable and economical implementation even with difficult materials such as Cryopellets.
  • a further object of the invention is to provide a separating device suitable for this purpose.
  • a supply of pellets is provided in a storage space.
  • the pellets are then passed out of the storage space into a downwardly out of the storage space and upwardly oriented metering channel such that forms a column of stacked pellets in the metering.
  • the lowest pellet of this column of pellets is located in a connection point, wherein an outlet channel is connected to the dosing channel at the connection point and continues transversely from the dosing channel.
  • a first pressure difference channel which opens into the dosing channel above the connection point by means of a first channel opening, is subjected to negative pressure, wherein a pellet is sucked to the first channel opening and consequently fixed locally there. This sucked pellet acts as a barrier for the pellets above it.
  • a second pressure difference channel which opens into the connection point by means of a second channel opening, subjected to overpressure, wherein the pellet located in the connection point is blown through the outlet channel and fed to the target container.
  • the holding negative pressure in the first, upper differential pressure channel is switched off, so that the pellet held at the first channel mouth moves towards the connection point and a new lowermost pellet is in the connection point.
  • one or more pellets can be separated from the large pellet supply and fed in the limited number to the target container, wherein the delimitation and also the feeding is carried out solely by the targeted application of negative pressure and overpressure. Due to the purely pneumatic handling, the mechanical effect on the pellets is very low. Even mechanically critical pellets such as Cryopellets can be reliably handled without that mechanical damage of the pellets such as abrasion or the like can be recorded. In the context of the invention, the density of the pellets, which is too low for delivery under weight, proves to be an advantage because the suction and fixing of the pellets as well as the transport by blow-out function effectively at the very low material densities typical here. Friction and other mechanical effects are reduced to a minimum, so that electrostatic charges or their possible effects are largely avoided or meaningless.
  • the first and the second channel mouth are arranged in a height difference from one another.
  • said height difference is an integer multiple of a mean diameter of the pellets. This ensures that below the barrier acting pellets a defined number of pellets is collected, which is then blown in exactly this number in the target container.
  • the integer multiple may be two, three, four or more, and specifies the number of pellets to be blown out into each target container.
  • the integer multiple is one, as a result of which exactly one pellet is blown out with each working cycle. However, this does not necessarily mean that even just one pellet is fed to the target container. Rather, a certain number of individual pellets can be blown by a certain number of cycles in the target container, whereby a high process reliability is given.
  • an embodiment of the separating device may also be expedient in which a plurality of first pressure difference channels open into the dosing channel by means of their associated first channel openings. Depending on requirements, then a more or less highly positioned channel mouth can be activated with negative pressure and serve as a barrier, in which case depending on the selected altitude, a more or less large number of pellets is collected below and ejected into the target container.
  • the demarcation of a certain number of pellets is based on the fact that negative pressure is built up in the first, upper pressure difference channel, as a result of which a pellet is sucked in and held on the associated first channel mouth, this sucked-in and held-on pellet being a barrier for the one above Pellets works. In this way, it is achieved that the one or more pellets collected underneath can be blown out in the intended number, without further pellets advancing prematurely from above and falsifying the previously delimited quantity.
  • the lowermost pellet simply rests on the bottom of the transverse outlet channel and lies in the area of action of the second pressure difference channel. As soon as a blast of compressed air is blown out through this second pressure difference channel, this and possibly also the subsequent pellets are carried away together with the compressed air or the compressed gas to the target container.
  • the lowest pellet is not simply allowed to stand up on the ground. Rather, the lowermost pellet is sucked before blowing to the second channel mouth by the negative pressure is temporarily applied to the second pressure difference channel.
  • a reliable tracking of the pellets is favored from top to bottom, especially taking into account the effect of low weight forces.
  • the lowermost pellet is reliably fixed at the channel mouth of the lower pressure difference channel with suction force and thereby accurately positioned. This favors a precise counting process as well as a later reproducible blow-out process.
  • the suction of the pellets acting as a barrier to the first channel mouth and the suction of the lowermost pellets to the second channel mouth occurs in temporal change. There may be temporal overlaps. In any case, however, it should be ensured that there are timeslots in which only one of the two pressure difference channels is subjected to negative pressure. This ensures that the intake at one of the two channel openings is not influenced in detail by the intake at the respective other channel opening.
  • the holding negative pressure in the first pressure difference channel is switched off. It may be sufficient that there remains ambient pressure or a slight, but no longer holding negative pressure.
  • the first pressure difference channel is subjected to overpressure. Even with only a slight overpressure, a back-up is supported or promoted downwards by the pellet initially held at the first channel mouth.
  • a protective gas is suitably used, wherein such a protective gas is advantageously introduced at an overpressurization of the first and / or the second pressure difference channel in the metering or in the outlet channel.
  • cryopellets are usually extremely hygroscopic.
  • the inert gas of the inerting of the pellets serve.
  • a pressure monitoring and / or a flow rate monitoring of the first and / or the second pressure difference channel is made.
  • the simple method according to the invention also requires a correspondingly simple held separating device, the essential Elements in the form of channels and the like can be readily incorporated into a body.
  • This makes it possible for a plurality of separating devices to be connected to one another in a modular manner and therefore to be flexibly constructed in the desired number and configuration. It may be expedient to design the required channels and the like as holes in such a body.
  • the storage space, the metering channel, the outlet channel, the first pressure difference channel and / or the second pressure difference channel are incorporated into the surface of such a body and closed by the main body of an adjacent separating device. On the one hand, this minimizes production costs. On the other hand, by disassembly good accessibility of all channels can be achieved, so that disturbances of any kind can be easily resolved.
  • Fig. 1 shows a schematic sectional view of a first embodiment of a separating device 3 according to the invention for the transfer of pellets 1, 1 ', 1 "in a schematically indicated target container 2.
  • the separating device 3 shown here and described below, thus executed inventive method are suitable for demarcation and the transfer of almost any pellets, but here are the most critical in handling Cryopellets and as an example of the pellets 1, 1 ', 1 "apply.
  • the separating device 3 comprises a storage space 4 for the pellets 1 and a downwardly out of the storage space 4 leading and upwardly oriented metering 5.
  • the storage space 4 is configured here as a funnel, which tapers in relation to the weighting direction down into the metering 5 inside.
  • the upright orientation of the metering 5 does not necessarily mean a precise vertical orientation. It can also be an inclined embodiment appropriate in which at least proportionately there is a significant vertical extent.
  • the scale used is a first longitudinal axis 28 of the dosing 5, which is in the usual operating position in the embodiment shown parallel to the direction of gravity, but also against the weight direction of gravity may have an inclination of not more than 45 ° and in particular of not more than 30 °.
  • the separating device 3 further comprises an outlet channel 6 which is connected to the dosing channel 5 at a connection point 7 and which continues transversely from the dosing channel 5.
  • the outlet channel 6 is arranged horizontally in the embodiment shown.
  • a second longitudinal axis 29 of the outlet channel 6 is therefore in the normal operating position perpendicular to the direction of the weight force or parallel to the horizontal.
  • it can also have an inclination of preferably not more than 45 ° and in particular of not more than 30 ° relative to the horizontal.
  • the separating device 3 comprises at least one, here exactly a first pressure difference channel 8 and a second pressure difference channel 10.
  • the first pressure difference channel 8 opens into the dosing channel 5 via a first channel opening 9 above the connection point 7.
  • the second pressure difference channel 10 opens into the connection point 7 by means of a second channel opening 11 below the first channel opening 9.
  • the first pressure difference channel 8 has a first channel axis 12
  • the second pressure difference channel 10 has a second channel axis 13.
  • the first channel axis 12 lies in the region of the associated channel opening 9 transversely to the first longitudinal axis 28 of the metering channel 5, while the second channel axis 13 of the second pressure difference channel 10 in the region of the associated channel mouth 11 is substantially parallel, here even coaxial with the second longitudinal axis 29 of the outlet channel 6 ,
  • the two pressure difference channels 8, 10 are provided at their associated channel openings 9, 11, each with a retaining means 18, 19, which prevent the penetration of foreign bodies and in particular of the pellets 1, 1 ', 1 "into the respective pressure difference channels 8, 10 the retaining means 18, 19, however, are gas-permeable, suitable in particular for this purpose are fine-pored filter materials such as sintered filters, membrane filters or the like.
  • both pressure difference channels 8, 10 can be acted upon alternately with negative pressure or with overpressure.
  • a negative pressure source 14 and also an overpressure source 15 are provided for both pressure difference channels 8, 10, wherein the first pressure difference channel 8 and the second pressure difference channel 10 are selectively connected by means of a respectively assigned changeover valve 16 with the associated vacuum source 14 or the associated overpressure source 15 can.
  • a position of the respective switching valve 16 is possible in which ambient pressure in each pressure difference channel 8, 10 sets.
  • protective gas containers 17 are provided as overpressure sources 15, in which protective gas is kept available under overpressure.
  • the protective gas under pressure from the respective protective gas container 17 by means of the first pressure difference channel 8 and / or the second pressure difference channel 10 through the respective associated channel mouth 9, 11 in the metering 5 and in the outlet. 6 initiated.
  • Fig. 1 two protective gas tank 17 located.
  • Fig. 1 initially provided a larger supply of several pellets 1 in the storage space 4.
  • the pellets 1 together with the separating device 3 form a self-tuned system, according to which the free passage cross section of the metering channel 5 and also the free passage cross section of the outlet channel 6 are slightly larger than a mean diameter D (FIG. Fig. 2 ) of the pellets 1.
  • the passage cross-section, in particular of the upright metering channel 5 is much greater than the average diameter D (FIG. Fig. 2 ), that although the pellets 1 can pass unhindered from top to bottom through the metering channel 5, but on the other hand pass two pellets simultaneously next to each other.
  • the free passage cross section of the dosing channel 5 is dimensioned such that the pellets 1 fall down from the storage space 4 into the dosing channel 5 and thereby form a column of pellets 1, 1 ', 1 "lying one above the other the in Fig. 1 shown initial position a bottom pellet 1 'in the junction 7 of the outlet channel 6 with the dosing 5. It may be appropriate that the bottom pellet 1' rests on the bottom of the outlet channel 6.
  • the second pressure difference channel 10 is initially subjected to negative pressure by being connected by means of the associated switching valve 16 with the associated vacuum source 14. As a result, the lowest pellet becomes 1 'to the second Channel mouth 11 sucked and pressed against the retaining means 19, whereby the lowest pellet 1 'is held in place.
  • the first, upper pressure difference channel 8 is acted upon by negative pressure, for which purpose the first pressure difference channel 8 is likewise connected by means of its changeover valve 16 to its associated negative pressure source 14.
  • the pellet 1 "is sucked from the column of pellets 1, which is closest to the associated channel mouth 9.
  • This pellet 1" is pressed against the retaining means 18 and fixed locally as long as the holding negative pressure in the upper pressure difference channel 8 is maintained becomes. On the one hand, this prevents the sucked-in pellet 1 "from slipping down into the connection point 7.
  • the sucked-in pellet 1" acts as a barrier for the pellets 1 above and thus prevents them from moving downward.
  • FIGS. 2 and 3 show a detail of the arrangement Fig. 1 in the execution of subsequent process steps.
  • a blow-out of those lower pellets 1 ' which are collected below the pellet 1 "fixed at the first channel mouth 9 as a barrier, is collected, this step being shown schematically in the sectional view Fig. 2 shown.
  • the second pressure difference channel 10 is acted upon over a defined period of time with overpressure, for which purpose it is connected by means of the associated changeover valve 16 with its associated overpressure source 15.
  • a gas pressure surge arises, as a result of which gas is injected according to an arrow 22 through the channel mouth 11 into the outlet channel 6 along its fourth channel axis 29.
  • the injected gas carries the previously sucked at the lower channel mouth 11 lowest pellet 1 'according to an arrow 23 through the outlet channel 6 in the ready target container 2.
  • a single gas shock for the blowing of a single lower pellet 1' or more simultaneously collected lower pellets 1 'ranges usually a single gas shock.
  • the next step is carried out according to Fig. 3
  • the holding negative pressure in the first pressure difference channel 8 is switched off so that the pellet 1 "held at the first channel mouth 9 (FIG. Fig. 2 ) moves towards the junction 7 and a new lowermost pellet 1 '( Fig. 3 ) is located in the connection point 7.
  • This move can take place solely as a result of the acting weight forces.
  • this is the lower, second pressure difference channel 10 again subjected to negative pressure, whereby again the respective lowest pellet 1 'is sucked before the later blowing to the second channel mouth 11.
  • the above-described pellet transfer from the upper, first channel opening 9 to the lower, second channel opening 11 according to an arrow 25 can also be supported by the fact that the first pressure difference channel 8 is briefly subjected to overpressure by means of its associated switching valve 16 with the associated overpressure source 15 is connected.
  • a pressure surge is formed, by means of which gas is introduced according to an arrow 24 through the channel mouth 9 in the metering channel 5 and thereby the advancement of the previously held at the first channel mouth 9 pellet 1 "( Fig. 2 ) is supported according to the arrow 25.
  • this overpressure surge prevents premature upward movement of the column of pellets 1 located above it.
  • a protective gas container 17 is provided as an overpressure source 15
  • the protective gas is introduced from the respective protective gas container 17 into the metering channel 5 or into the outlet channel 6 in the above-described pressure surges by the first and / or the second pressure difference channel 8, 10.
  • a protective gas atmosphere can be maintained in all regions of the separating device according to the invention which interact with the pellets 1, 1 ', 1 ", which allows the handling of very pronounced hygroscopic cryopellets and, if required, also enables inerting of the pellets 1, 1 ', 1".
  • the negative pressure of the two pressure difference channels 8, 10 may overlap in time by a certain amount.
  • the temporary negative pressure in the lower, second pressure difference channel 10 also supports the advancement of the pellets 1 from the target container 2 into the metering channel 5. This can also be done for the initial filling of the metering channel 5 with pellets 1, 1 ', 1 "to achieve the starting position Fig. 1 be used.
  • first pressure difference channel 8 is again subjected to negative pressure, as a result of which a new, serving as a barrier pellet 1 "is sucked in and fixed Fig. 1 is again restored, and the process cycle described above may begin again.
  • Fig. 1 The representation after Fig. 1 is still removable, that in the region of the first and / or the second pressure difference channel 8, 10 monitoring means are arranged, which are configured here for example as a pressure sensor 26 and / or as a flow sensor 27 and connected to a suitable, not shown here for simplicity monitoring unit. In this way, a pressure monitoring and / or a flow rate monitoring can be made and errors are detected in the process flow.
  • Fig. 4 shows a schematic sectional view of a variant of the arrangement according to the Fig. 1 to 3 , wherein several, here exemplarily three first pressure difference channels 8, 8 ', 8 "open into the dosing channel 5 by means of their associated first channel openings 9, 9', 9".
  • the uppermost first channel opening 9 lies in a height difference ⁇ H above the second channel opening 11, where analogous to the embodiment of the Fig. 1 to 3 this height difference .DELTA.H is at least approximately an integer multiple of the mean diameter D. In the exemplary embodiment shown, this integer multiple 3.
  • first pressure difference channels 8, 8 ', 8 " If, therefore, the top of the plurality of first pressure difference channels 8, 8 ', 8 ", so here the pressure difference channel 8 is subjected to negative pressure, formed at the associated channel mouth 9 a lock by an adhesive or sucked Pellet 1 ", below which exactly three lower pellets 1 'collected and according to the procedure of the Fig. 1 to 3 be blown into the respective target container 2.
  • one of the other first pressure difference channels 8 ', 8 " can also be subjected to negative pressure, which then results in a delimitation of exactly one or exactly two lower pellets 1.
  • the embodiment is correct Fig. 4 with the one after the Fig. 1 to 3 match.
  • Fig. 5 shows in a perspective view a cuboid base body 20 for forming a single separating device 3 after the Fig. 1 to 3 and 6 , It may be expedient to introduce bores, openings or the like in such a base body 20 in order to thereby form the various channels described above. By two such holes, the two pressure difference channels 8, 10 are formed in the illustrated embodiment. Deviating from this, the storage space 4, the metering channel 5 and the outlet channel 6 are incorporated into a surface 21 of the main body 20 as a channel-like recess and initially open to the outside. But it may also be expedient to additionally form the two pressure difference channels 8, 10 or another part of the aforementioned elements in this one surface 21.
  • Several such basic body 20 can be according to the perspective view Fig. 6 connect in a linear series, the said channel-like depressions in a base body 20 are closed by the adjacent base body 20 ', and whereby modularly connected singulating devices 3, 3' are formed.
  • Fig. 8 Deviating from this shows Fig. 8 in a plan view of a base body 20 whose plan is circular segment. Again, the various channels on a side surface 21 analogous to Fig. 5 be educated. By way of example, however, the storage space 4, the metering channel 5 and also the other elements are incorporated centrally in the base body 20 here.
  • Fig. 9 shows in a perspective bottom view a group of several basic bodies 20, 20 ' Fig. 8 , which are connected to each other in a modular manner adjacent to each other and form a total of a circularly arranged group of separating devices 3, 3 'due to the circular segment shape of a single body 20.
  • individual separating devices 3 ' may be missing, which are shown here only by dashed lines for the sake of simplicity, resulting in a total circular segment shape of the group of separating devices 3 results.
  • outlet openings 30 of the outlet channels 6 are arranged on the underside of the base body 20. Details of this can be found in the schematic sectional view of the main body 20 Fig. 7 : In deviation from the embodiment according to Fig. 1 only the immediately adjacent to the junction 7 part of the outlet channel 6 extends transversely to the metering 5 and transverse to the direction of gravity, while an adjoining channel segment 6 'of the outlet channel 6 is angled down and leads by means of the lower outlet opening 30 to the target container 2 positioned underneath ,

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Air Transport Of Granular Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)

Claims (14)

  1. Procédé pour séparer et pour transférer des pastilles (1), en particulier des cryopastilles, dans un récipient cible (2), dans lequel une réserve de pastilles (1) est préparée dans un réservoir (4),
    dans lequel les pastilles (1), à partir de l'espace de réserve (4), sont amenées dans un conduit de dosage (5) sortant dudit espace de réserve (4) vers le bas et orienté verticalement, de telle sorte qu'il se forme dans le conduit de dosage (5) une colonne de pastilles (1) superposées, et dans lequel la pastille inférieure (1') de cette colonne de pastilles (1) se trouve à un point de liaison (7), caractérisé en ce qu'à ce point de liaison (7), un conduit de sortie (6) est relié au conduit de dosage (5) et s'éloigne de celui-ci transversalement,
    le procédé comprenant les étapes de procédé supplémentaires suivantes :
    - un premier conduit de pression différentielle (8), qui débouche dans le conduit de dosage (5) au-dessus du point de liaison (7) à l'aide d'un premier débouché de conduit (9), subit une dépression, moyennant quoi une pastille (1") est aspirée contre le premier débouché de conduit (9) et est ainsi fixée spatialement à cet endroit, et cette pastille (1") aspirée agit comme un barrage pour les pastilles (1) qui se trouvent au-dessus,
    - un deuxième conduit de pression différentielle (10), qui débouche dans le point de liaison (7) à l'aide d'un deuxième débouché de conduit (11), subit une surpression, moyennant quoi la pastille (1") qui se trouve dans le point de liaison (7) est expulsée par le conduit de sortie (6) et amenée dans le récipient cible (2),
    - après l'expulsion de la pastille inférieure (1'), la dépression maintenue est supprimée dans le conduit de pression différentielle (8), de sorte que la pastille (1") retenue contre le premier débouché de conduit (9) avance à son tour en direction du point de liaison (7), et qu'une nouvelle pastille inférieure (1') se trouve dans le point de liaison (7).
  2. Procédé selon la revendication 1,
    caractérisé en ce que la pastille inférieure (1'), avant son expulsion, est aspirée contre le deuxième débouché de conduit (11) grâce au fait que le deuxième conduit de pression différentielle (10) subisse une dépression.
  3. Procédé selon la revendication 2,
    caractérisé en ce que l'aspiration de la pastille (1") agissant comme barrage contre le premier débouché de conduit (9) et l'aspiration de la pastille inférieure (1') contre le deuxième débouché de conduit (11) ont lieu en alternance temporelle.
  4. Procédé selon l'une des revendications 1 à 3,
    caractérisé en ce que le premier conduit de pression différentielle (8), pour renforcer l'avance de la pastille (1") retenue contre le premier débouché de conduite (9), subit une surpression.
  5. Procédé selon l'une des revendications 1 à 4,
    caractérisé en ce que lors d'une surpression du premier et/ou du deuxième conduit de pression différentielle (8, 10), un gaz de protection est introduit dans le conduit de dosage (5) et dans le conduit de sortie (6), respectivement.
  6. Procédé selon l'une des revendications 1 à 5,
    caractérisé en ce qu'une surveillance de pression et/ou une surveillance de débit des premier et/ou deuxième conduits de pression différentielle (8, 10) est réalisée.
  7. Dispositif d'isolement (3) pour la mise en oeuvre du procédé selon l'une des revendications 1 à 6,
    comprenant un espace de réserve (4) pour les pastilles (1), un conduit de dosage (5) sortant dudit espace de réserve (4) vers le bas et orienté verticalement, un conduit de sortie (6) qui est relié au conduit de dosage (5) en un point de liaison (7) et s'éloigne du conduit de dosage (5) transversalement, au moins un premier conduit de pression différentielle (8), qui débouche dans le conduit de dosage (5) au-dessus du point de liaison (7) à l'aide d'un premier débouché de conduit (9), et un deuxième conduit de pression différentielle (10) qui débouche dans le point de liaison (7) à l'aide d'un deuxième débouché de conduit (11), dans lequel le premier conduit de pression différentielle (8) est apte à subir une dépression, et le deuxième conduit de pression différentielle (8) est apte à subir une surpression.
  8. Dispositif d'isolement selon la revendication 7,
    caractérisé en ce que les premier et deuxième débouchés de conduit (9, 11) sont disposés avec une différence de hauteur (ΔH) l'un par rapport à l'autre, dans lequel la différence de hauteur (ΔH) est égale à un multiple entier d'un diamètre moyen (D) des pastilles (1).
  9. Dispositif d'isolement selon la revendication 8,
    caractérisé en ce que le multiple entier est égal à un.
  10. Dispositif d'isolement selon l'une des revendications 7 à 9,
    caractérisé en ce que plusieurs premiers conduits de pression différentielle (8, 8', 8") débouchent dans le conduit de dosage (5) à l'aide de leur premier débouché de conduit (9, 9', 9") associé.
  11. Dispositif d'isolement selon l'une des revendications 7 à 10,
    caractérisé en ce que plusieurs dispositifs d'isolement (3, 3') sont reliés entre eux de manière modulaire.
  12. Dispositif d'isolement selon la revendication 11,
    caractérisé en ce que le dispositif d'isolement (3) comporte un corps de base (20) avec une surface extérieure (21), dans lequel l'espace de réserve (4), le conduit de dosage (5), le conduit de sortie (6), le premier conduit de pression différentielle (8) et/ou le deuxième conduit de pression différentielle (10) est réalisé dans la surface (21) du corps de base (20) et est obturé par le corps de base (20') du dispositif d'isolement (3') voisin.
  13. Dispositif d'isolement selon la revendication 11 ou 12,
    caractérisé en ce que les dispositifs d'isolement (3, 3') comportent des corps de base (20, 20') parallélépipédiques et sont reliés entre eux sur une rangée linéaire.
  14. Dispositif d'isolement selon la revendication 11 ou 12,
    caractérisé en ce que les dispositifs d'isolement (3, 3') comportent des corps de base (20, 20') en forme d'arc de cercle, vus en plan, et sont reliés entre eux en forme de cercle ou en forme d'arc de cercle.
EP15739179.8A 2015-07-18 2015-07-18 Procédé et dispositif de séparation et de transfert de pastilles Active EP3325354B1 (fr)

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US10556712B2 (en) 2020-02-11
EP3325354A1 (fr) 2018-05-30
CN108025823B (zh) 2019-12-27
CN108025823A (zh) 2018-05-11
CA2992325A1 (fr) 2017-01-26
WO2017012628A1 (fr) 2017-01-26
ES2742148T3 (es) 2020-02-13
CA2992325C (fr) 2022-04-19
US20180141689A1 (en) 2018-05-24

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