EP2139777B1 - Emballage pour la sterilisation par uv - Google Patents

Emballage pour la sterilisation par uv Download PDF

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Publication number
EP2139777B1
EP2139777B1 EP08716505A EP08716505A EP2139777B1 EP 2139777 B1 EP2139777 B1 EP 2139777B1 EP 08716505 A EP08716505 A EP 08716505A EP 08716505 A EP08716505 A EP 08716505A EP 2139777 B1 EP2139777 B1 EP 2139777B1
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EP
European Patent Office
Prior art keywords
process according
product
film
packaging
radiation
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Active
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EP08716505A
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German (de)
English (en)
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EP2139777A1 (fr
Inventor
Detlef Busch
Dirk Walgenbach
Bertram Schmitz
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Treofan Germany GmbH and Co KG
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Treofan Germany GmbH and Co KG
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/12—Sterilising contents prior to, or during, packaging
    • B65B55/16—Sterilising contents prior to, or during, packaging by irradiation

Definitions

  • the invention relates to a packaging with food and / or utensils that are sterilized or sanitized for hygienic reasons.
  • the invention also relates to a process for the sterilization, sterilization or partial sterilization of packaged goods.
  • a UV treatment of the washing and Transport water with which the food is pre-cleaned is required.
  • an additional UV treatment of the product to be packaged is required.
  • the different foods or goods pass through an area in which they are exposed to the UV radiation for a certain period of time in order to achieve a certain rate of sterilization.
  • the goal is to kill 90% of the germs on the surface and then pack the product under sterile conditions.
  • UV irradiation for sterilizing products is becoming increasingly important, since this method has many advantages over sterilization processes with peroxides or superheated steam.
  • the procedures are easy to apply, the product properties are not affected and the sterilization is very effective. No residue, no corrosive or harmful substances are produced during the treatment, the smell and taste of the food is not changed and the systems have low purchase and maintenance costs.
  • UVC rays are shorter wavelength and higher in energy than UVA and UVB rays. They cover most of the entire UV range and have a strong germicidal (bactericidal) effect. Like the visible wavelengths of light, UVC rays only move in a straight line and decrease in intensity as the distance from the source increases. UVC rays do not penetrate any substances, even window glass.
  • UVC radiation is technically produced by mercury lamps, whose primary radiation of 254nm, very close to the bactericidal effect maximum.
  • low, high or medium pressure lamps are used.
  • Low efficiency tubes with an efficiency of more than 90% in the bactericidal wavelength range are still unsurpassed in their efficiency.
  • the remaining radiation from a low-pressure tube is distributed to secondary emissions such as light (above 400nm) and heat.
  • UVC rays The germicidal effect of UVC rays is based on the following effects.
  • the short-wave and high-energy UVC rays are in certain areas of the DNA (DNA) is absorbed. This leads to a photo-chemical change in certain areas of the helix, for example to chain-linking reactions of adjacent functional groups. These become unusable for the copying process of the helix strand which works according to the template principle. The necessary information transfer is omitted. The cell can not multiply anymore.
  • the cell dies without proliferating. As a consequence of this principle of action, germs in the true sense are not killed. Rather, they are inactivated and thus prevented from building up a critical potential by cell division.
  • This object is achieved by a method for sterilizing, partial sterilization or sterilization of products by means of UV radiation, wherein the product is first encased in a UVC-permeable packaging material and then sterilized in the packaged state by irradiation with UVC radiation, partially sterilized or sterilized, the Packaging material as a main component comprises a polymer of at least one aliphatic hydroxycarboxylic acid.
  • packaging materials were found which, contrary to the prejudice in the prior art, are sufficiently permeable to UVC radiation.
  • inventive method offers the extraordinary advantage that the products are sterilized in their packaging or together with the packaging material by means of UVC radiation. This virtually completely eliminates recontamination after sterilization of the products on the way to packaging.
  • the packaging material consists of an unstretched (cast film), a monoaxially oriented or a biaxially oriented polyhydroxycarboxylic acid film, which may have one or more layers.
  • Other suitable packaging forms are containers, trays or similar shapes.
  • the main component of these packaging materials is a polymer of at least one aliphatic hydroxycarboxylic acid.
  • the packaging material or the film contains at least 70-100% by weight of polymer of aliphatic polyhydroxycarboxylic acid, preferably PLA (polylactic acid).
  • Embodiments are preferred from 80-99 wt .-%, preferably 85-95 wt .-% of said polymers, each based on the weight of the packaging material.
  • Multilayer films are generally composed of a thick base layer which has the largest layer thickness and accounts for 60 to 100% of the total thickness of the film. This base layer is optionally provided on one side or both sides, with cover layer / s. In further embodiments, additional interlayers or coatings are possible on the outer surface of the monolayer or multilayer film to yield four- or five-layer, coated or uncoated, films.
  • the thickness of the cover layer is generally in a range of 0.5 to 20 .mu.m, preferably 0.5 to 10 .mu.m, in particular 1 to 5 .mu.m.
  • the total thickness of the film is according to the invention in a range of 20 to 100 .mu.m, preferably 25 to 150 .mu.m, in particular 30 to 100 .mu.m.
  • the cover layers are the layers which form the outer layers of the film. Interlayers are naturally applied between the base layer and the cover layers. The following remarks on the layers of the film apply mutatis mutandis in the same way for single-layer embodiments of the film.
  • the layer or layers of the film contains / contains from 70 to about 100% by weight, preferably 80 to 98 wt .-% of a polymer of at least one aliphatic hydroxycarboxylic, hereinafter also called PHC or polyhydroxycarboxylic acids.
  • PHC polyhydroxycarboxylic
  • polylactic acids are particularly suitable. These are hereinafter referred to as PLA (polylactidacide).
  • PLA polylactidacide
  • PLA polylactidacide
  • PLA aliphatic polyhydroxycarboxylic acid
  • monomers of the aliphatic polyhydroxycarboxylic acid (PHC) in particular aliphatic mono-, di- or trihydroxycarboxylic acids or their dimeric cyclic esters are suitable, among which lactic acid in its D or L form is preferred.
  • Such polymers are known per se in the art and are commercially available.
  • the production of polylactic acid is also described in the prior art and is carried out via catalytic ring-opening polymerization of lactide (1,4-dioxane-3,6-dimethyl-2,5-dione), the dimeric cyclic ester of lactic acid, therefore PLA is often also called polylactide designated.
  • the following publications describe the preparation of PLA US 5,208,297 . US 5,247,058 or US 5,357,035 ,
  • polylactic acids which are composed exclusively of lactic acid units.
  • PLA homopolymers which contain 80-100% by weight of L-lactic acid units corresponding to 0 to 20% by weight of D-lactic acid units are preferred.
  • D-lactic acid units can be included as a comonomer.
  • the polylactic acid may additionally comprise as comonomer aliphatic polyhydroxycarboxylic acid units other than lactic acid, for example glycolic acid units, 3-hydroxypropanoic acid units, 2,2-dimethyl-3-hydroxypropanoic acid units or higher homologues of hydroxycarboxylic acids having up to 5 carbon atoms.
  • the molecular weight of the PLA is in a range of at least 10,000 to 500,000 (number average), preferably 50,000 to 300,000 (number average).
  • the glass transition temperature Tg is in a range of 40 to 100 ° C, preferably 40 to 80 ° C.
  • the individual layers of the film each contain 70 to about 100 wt .-% of the polymers described above, preferably 80 to 98 wt .-%, and optionally additionally additives such as neutralizing agents, stabilizers, lubricants, antistatic agents and other additives, provided that the UVC Do not obstruct permeability. They are expediently added to the polymer or the polymer mixture before melting. Stabilizers used are, for example, phosphorus compounds, such as phosphoric acid or phosphoric acid esters. In principle, the individual layers may have the same or different composition / s with respect to polymer and additization. In general, the composition of the base layer will be different from the composition of the remaining layers. In particular, additives such as antiblocking agents or lubricants are added to the outer layers. Neutralizers and stabilizers are generally present in all layers in respective effective amounts. However, the structure and composition of the individual layers of the film can fundamentally vary within wide limits.
  • the film can be coated to optimize other properties.
  • These coatings may be based on the above-described PHC polymers or, in turn, should be transparent to UVC radiation.
  • Typical coatings are adhesion-promoting, slip-improving or dehesive layers.
  • these additional layers may be over-lined by means of aqueous or nonaqueous dispersions prior to cross-stretching or applied off-line.
  • the PHC film is produced by the per se known extrusion or coextrusion process.
  • the melt (s) corresponding to the layers of the film are coextruded through a flat die, and the single or multilayer film thus obtained is drawn off on one or more rolls for solidification.
  • the film is then mono- or biaxially stretched (oriented), the stretched film heat-set.
  • the films on the surface layer provided for treatment on one or both sides corona or flame treated.
  • the stretching in the longitudinal direction preferably takes place with the aid of two rolls running at different speeds in accordance with the desired stretch ratio. For cross-stretching you generally use a corresponding clip frame.
  • the biaxial orientation can also be simultaneously carried out for example by means LISIM ® technology.
  • the further description of the film production takes place using the example of a flat film extrusion with subsequent sequential stretching.
  • the melt (s) are pressed through a flat die (slot die) and the squeezed film is drawn off on one or more draw rolls at a temperature of 10 to 100 ° C, preferably 20 to 80 ° C, cooling and solidifying.
  • the film thus obtained is then stretched longitudinally and transversely to the extrusion direction.
  • the lengthwise stretching is preferably carried out at a roll temperature of the draw rolls of 40 to 130 ° C., preferably 50 to 100 ° C., expediently with the aid of two rolls running at different speeds in accordance with the desired draw ratio, and the transverse stretching preferably at a temperature of 50 to 130 ° C., preferably 60 to 120 ° C using a corresponding clip frame.
  • the Longitudinal stretching ratios can be varied in the range of 1.5 to 8, preferably 1.5 to 4.
  • the transverse stretching ratios are in the range of 3 to 10, preferably 4 to 7.
  • the stretching of the film is followed by its heat setting (heat treatment), wherein the film is held convergently for about 0.1 to 10 seconds at a temperature of 60 to 150 ° C (convergence up to 25%). Subsequently, the film is wound in the usual manner with a winding device.
  • containers, bowls, bottles or other forms are suitable. These containers are made from the above-described polyhydroxycarboxylic acids, preferably PLA, as described above in connection with the films.
  • the rheological properties of the polymer must be adapted to the particular processing method, for example, the manufacture of injection molded or blow molded containers requires a different melt flow index of the PLA as a film raw material.
  • the suitable raw materials from the PLA polymers known per se.
  • any conventional packaging technologies and filling processes may be used, for example film wrapping on HFFS or VFFS packing machines.
  • the sterilization according to the invention partial sterilization or sterilization by UV radiation takes place.
  • the packaged product is suitably exposed in the package to UV radiation comprising the wavelength range of 254 nm (UVC).
  • UV radiation comprising the wavelength range of 254 nm (UVC).
  • UV-C radiation is produced technically by mercury lamps, for example by low-pressure lamps, optionally also by high or medium pressure lamps.
  • the UV lamps generally consist of a housing with a quartz glass window as an exit window for the radiation and the actual mercury discharge lamp.
  • Low-pressure tubes are preferred because they are very effective with a very high efficiency of over 80% in the bactericidal wavelength range of about 254nm.
  • these lamps also emit radiation at other wavelengths, for example in the range of 200 to 280 nm, but have the relevant range from about 254nm the highest intensity.
  • high-performance low-pressure mercury lamps are used, which are provided with a cooling device. The cooling prevents heating and the associated shift in the spectrum. These lamps are characterized by a very high and constant power outputs.
  • the radiant power of the UV lamps used can basically vary within a wide range, for example between 50 and 250W, preferably between 100 and 150W.
  • a ballast can be used to power, control and monitor the operating parameters. The irradiance can be adjusted individually to the respective sterilization or degermination process, or the contents.
  • the irradiance indicates the radiation power per area and is for example 10 to 200 mW / cm 2 , preferably 50 to 150 mW / cm 2 .
  • the speed of the band can be used to regulate the irradiation time and thus the irradiation dose.
  • the metering can also be effected via corresponding filters which influence the transmission of the UV radiation produced.
  • all three parameters should be set and optimized for the best possible efficiency.
  • the irradiation dose can be adjusted both on the irradiation time and on the irradiance.
  • the contents can also be pre-cleaned by per se known processes, or be sterilized in advance and subsequently treated by means of the sterilization or sterilization process according to the invention.
  • all types of filling products can be sterilized or sterilized by means of the process according to the invention, for example piece goods, products, powders, grains, liquids and water, for example packaged in bottles.
  • the products are all products in which sterilization and sterile storage is required, such as food, other perishables, medical products, such as disposable syringes dressing material or implants.
  • the method according to the invention makes use of all advantages of the UV sterilization or UV sterilization known per se and avoids recontamination of the products on the way from the sterilization to packaging, or until the intended use, since the packaging after sterilization before said recontamination reliably protects.
  • This sanitizing system is thus extremely effective and easy to use.
  • the product properties are not affected and no residues, side effects or by-products are produced.
  • the process leads in a single step to a germ-free packaged good, which ensures the quality and shelf life in the easiest way.
  • the packaging according to the invention will not be provided with a print or other applications which could hinder the passage of the UV radiation.
  • small-area imprints such as Data or barcodes that do not interfere with the product.
  • the germ-free packaging with contents after sterilization can additionally be provided with a further outer packaging or labels, which in turn have decorative or informative elements, for example wrap-around labels, self-adhesive labels, whole or partial printing or a metal coating for protection against gas or water vapor transmissions or the action of light.
  • This outer packaging must meet no special requirements in terms of sterility and can therefore be selected depending on the application of the variety of packaging materials known per se for functionality or appearance.
  • the base layer was nearly 100% by weight of a polylactic acid with a melting point of about 160 ° C.
  • the layer additionally contained stabilizers and neutralizing agents in conventional amounts.
  • the two sealable outer layers were essentially composed of an amorphous polylactic acid, this polylactic acid having a UD ratio of about 40/60.
  • the cover layers each contained 0.1% by weight of SiO 2 -based particles as antiblocking agents. The thickness of the cover layers was 2.5 ⁇ m in each case.
  • a bag package was made.
  • the pouch packaging was filled with strawberries and sealed. Subsequently, the filled, closed by sealing seams package was placed under a low pressure mercury lamp for 30 sec and then stored at a temperature of about 10 ° C for 7 days.
  • a bag packaging was prepared.
  • the pouch packaging was filled with strawberries and sealed.
  • the packaging was stored without previous UV disinfection at a temperature of about 10 ° C for 7 days.
  • the cover layers had a thickness of 0.6 ⁇ m in each case.
  • the base layer was made of propylene homopolymer with a Melting point of 166 ° C and a melt flow index of 3.4 g / 10min and N, N-bis-ethoxyalkylamine as an antistatic agent.
  • the cover layers consisted of random ethylene-propylene copolymers having a C 2 content of 4.5% by weight and 0.33% by weight SiO 2 as antiblocking agent with an average particle size of 2 ⁇ m and 0.90% by weight. % Polydimethylsiloxane.
  • a bag package was made.
  • the pouch packaging was filled with strawberries and sealed. Subsequently, the filled, sealed by sealing seams package was placed under a low pressure mercury lamp for 30 sec and stored at a temperature of about 10 ° C for 7 days.
  • Example 3 the strawberries which were packed according to Example 1 and UV-sterilized showed no signs of decay or mold, whereas without UV sterilization (Example 2) or with oPP film despite UV sterilization (Example 3) significant spoilage traces were observed.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Wrappers (AREA)
  • Packages (AREA)

Claims (19)

  1. Procédé de désinfection, de désinfection partielle ou de stérilisation de produits au moyen d'un rayonnement UV, le produit étant d'abord enveloppé d'une matière d'emballage perméable aux UVC et désinfecté, partiellement désinfecté ou stérilisé ensuite à l'état emballé, par irradiation au rayonnement UVC, caractérisé en ce que la matière d'emballage comprend en tant que composant principal un polymère d'au moins un acide carboxylique hydroxy aliphatique.
  2. Procédé selon la revendication 1, caractérisé en ce que la matière d'emballage est un film.
  3. Procédé selon la revendication 1, caractérisé en ce que la matière d'emballage est un récipient.
  4. Procédé selon la revendication 1, caractérisé en ce que la matière d'emballage est une combinaison d'une coque avec couvercle ou opercule.
  5. Procédé selon la revendication 1, caractérisé en ce que la matière d'emballage est une bouteille.
  6. Procédé selon l'une quelconque des revendications 1 à 5, caractérisé en ce que l'irradiation par UV s'effectue au moyen d'une lampe à vapeur de mercure.
  7. Procédé selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le produit est un produit agro-alimentaire ou une denrée alimentaire.
  8. Procédé selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le produit est un produit médical.
  9. Procédé selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le produit est un tampon.
  10. Procédé selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le produit est un produit cosmétique.
  11. Procédé selon l'une quelconque des revendications 1 à 6, caractérisé en ce que le produit est un produit liquide.
  12. Procédé selon l'une quelconque des revendications 1 à 5, caractérisé en ce que le produit est de l'eau.
  13. Procédé selon la revendication 2, caractérisé en ce que le film contient de 80 à < 98 % en poids d'un polymère d'un acide carboxylique hydroxy aliphatique.
  14. Procédé selon la revendication 13, caractérisé en ce que le film comporte sur les deux faces des couches de couverture et en ce que les couches de couverture contiennent de 70 à <100 % en poids d'un polymère d'un acide carboxylique hydroxy aliphatique.
  15. Procédé selon l'une quelconque des revendications 2, 13 ou 14, caractérisé en ce que l'acide carboxylique hydroxy aliphatique est un acide polylactique.
  16. Procédé selon l'une quelconque des revendications 2, 13 à 15, caractérisé en ce que le film a une épaisseur totale d'au moins 20 à 100 µm.
  17. Procédé selon l'une quelconque des revendications 2, 13 à 16, caractérisé en ce qu'au moins une couche de couverture est scellable.
  18. Procédé selon l'une quelconque des revendications précédentes, caractérisé en ce qu'on munit l'emballage d'un suremballage supplémentaire.
  19. Procédé selon l'une quelconque des revendications précédentes, caractérisé en ce qu'on munit l'emballage d'une étiquette.
EP08716505A 2007-03-16 2008-03-13 Emballage pour la sterilisation par uv Active EP2139777B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007012623 2007-03-16
PCT/EP2008/002008 WO2008113509A1 (fr) 2007-03-16 2008-03-13 Emballage pour la stérilisation par uv

Publications (2)

Publication Number Publication Date
EP2139777A1 EP2139777A1 (fr) 2010-01-06
EP2139777B1 true EP2139777B1 (fr) 2012-09-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP08716505A Active EP2139777B1 (fr) 2007-03-16 2008-03-13 Emballage pour la sterilisation par uv

Country Status (5)

Country Link
US (1) US9309018B2 (fr)
EP (1) EP2139777B1 (fr)
CA (1) CA2680082C (fr)
ES (1) ES2397873T3 (fr)
WO (1) WO2008113509A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022121420A1 (fr) * 2020-12-09 2022-06-16 华南农业大学 Synergiste de stérilisation aux ultraviolets et procédé de stérilisation utilisant celui-ci en combinaison avec des ultraviolets

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US4112124A (en) * 1971-04-26 1978-09-05 Drisan Packaging Ltd. Food packaging system and method
CH572415A5 (fr) 1974-04-10 1976-02-13 Aluminiumwerke Ag Rorschach
DE3545116A1 (de) * 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
JPH0797957B2 (ja) * 1988-08-29 1995-10-25 呉羽化学工業株式会社 真空包装生肉の殺菌方法
US5208297A (en) * 1991-12-30 1993-05-04 E. I. Du Pont De Nemours And Company Rare earth metal coordination compounds as lactone polymerization catalysts
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
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US5326542A (en) * 1992-10-01 1994-07-05 Tetra Laval Holdings & Finance S.A. Method and apparatus for sterilizing cartons
US5489022A (en) * 1994-04-19 1996-02-06 Sabin Corporation Ultraviolet light absorbing and transparent packaging laminate
US5817728A (en) * 1995-03-16 1998-10-06 Mitsui Chemicals, Inc. Preparation of degradable copolymers
US6433344B1 (en) * 1996-05-22 2002-08-13 Purepulse Technologies, Inc. Pulsed light sterilization of drinking water and drinking water containers
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WO1998036907A1 (fr) 1997-02-19 1998-08-27 Nippon Foil Mfg. Co., Ltd. Materiau d'emballage et contenant
FR2773715A1 (fr) * 1998-01-20 1999-07-23 Becton Dickinson France Procede d'introduction d'objets conditionnes dans une zone sterile
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US20040219056A1 (en) * 2000-10-26 2004-11-04 Zamir Tribelsky Disinfection through packaging
IL158425A0 (en) * 2001-04-30 2004-05-12 Trespaphan Gmbh Polyactic acid (pla) film having good antistatic properties
DE60216029T2 (de) * 2001-09-26 2007-06-21 Kabushiki Kaisha Toshiba Copolymer-Harzzusammensetzung und Verfahren zu seiner Herstellung
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Also Published As

Publication number Publication date
CA2680082C (fr) 2016-06-14
US20100092627A1 (en) 2010-04-15
CA2680082A1 (fr) 2008-09-25
WO2008113509A1 (fr) 2008-09-25
ES2397873T3 (es) 2013-03-12
US9309018B2 (en) 2016-04-12
EP2139777A1 (fr) 2010-01-06

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