EP1997522A4 - Biologisch abbaubares magnesiummaterial zur medizinischen verwendung - Google Patents

Biologisch abbaubares magnesiummaterial zur medizinischen verwendung

Info

Publication number
EP1997522A4
EP1997522A4 EP07739014A EP07739014A EP1997522A4 EP 1997522 A4 EP1997522 A4 EP 1997522A4 EP 07739014 A EP07739014 A EP 07739014A EP 07739014 A EP07739014 A EP 07739014A EP 1997522 A4 EP1997522 A4 EP 1997522A4
Authority
EP
European Patent Office
Prior art keywords
medical use
magnesium material
biodegradable magnesium
biodegradable
medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07739014A
Other languages
English (en)
French (fr)
Other versions
EP1997522A1 (de
EP1997522B1 (de
Inventor
Sachiko Hiromoto
Akiko Yamamoto
Norio Maruyama
Toshiji Mukai
Hidetoshi Somekawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute for Materials Science
Original Assignee
National Institute for Materials Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Institute for Materials Science filed Critical National Institute for Materials Science
Publication of EP1997522A1 publication Critical patent/EP1997522A1/de
Publication of EP1997522A4 publication Critical patent/EP1997522A4/de
Application granted granted Critical
Publication of EP1997522B1 publication Critical patent/EP1997522B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • A61L27/047Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/306Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/022Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • A61L31/088Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EP20070739014 2006-03-20 2007-03-19 Verfahren zur kontrolle der abbauszeit einer biologisch abbaubaren vorrichtung Not-in-force EP1997522B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006077776 2006-03-20
PCT/JP2007/055571 WO2007108450A1 (ja) 2006-03-20 2007-03-19 医療用生分解性マグネシウム材

Publications (3)

Publication Number Publication Date
EP1997522A1 EP1997522A1 (de) 2008-12-03
EP1997522A4 true EP1997522A4 (de) 2011-11-02
EP1997522B1 EP1997522B1 (de) 2015-05-13

Family

ID=38522479

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20070739014 Not-in-force EP1997522B1 (de) 2006-03-20 2007-03-19 Verfahren zur kontrolle der abbauszeit einer biologisch abbaubaren vorrichtung

Country Status (4)

Country Link
US (1) US20090131540A1 (de)
EP (1) EP1997522B1 (de)
JP (1) JPWO2007108450A1 (de)
WO (1) WO2007108450A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108431261A (zh) * 2015-12-28 2018-08-21 韩国机械研究院 具有优异的机械性能和耐腐蚀性的镁合金及其制造方法

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
EP2054537A2 (de) 2006-08-02 2009-05-06 Boston Scientific Scimed, Inc. Endoprothese mit dreidimensionaler desintegrationssteuerung
CA2663250A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
CA2663220A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
US8057534B2 (en) 2006-09-15 2011-11-15 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
EP2210625B8 (de) 2006-09-15 2012-02-29 Boston Scientific Scimed, Inc. Biologisch erodierbare Endoprothese mit biostabilen anorganischen Schichten
EP2068962B1 (de) 2006-09-18 2013-01-30 Boston Scientific Limited Endoprothesen
US20080069858A1 (en) * 2006-09-20 2008-03-20 Boston Scientific Scimed, Inc. Medical devices having biodegradable polymeric regions with overlying hard, thin layers
JP5355418B2 (ja) 2006-12-28 2013-11-27 ボストン サイエンティフィック リミテッド 生侵食性内部人工器官、及び該生侵食性内部人工器官を製造する方法
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US8172908B2 (en) * 2008-01-17 2012-05-08 The University Of Hong Kong Implant for tissue engineering
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
JP5328013B2 (ja) * 2008-07-02 2013-10-30 学校法人千葉工業大学 酸化マグネシウム皮膜の形成方法
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
JP2010057590A (ja) * 2008-09-02 2010-03-18 Olympus Corp 移植材とその製造方法
JP2010063534A (ja) * 2008-09-09 2010-03-25 Olympus Corp 移植材とその製造方法
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
JP2010125156A (ja) * 2008-11-28 2010-06-10 Olympus Corp 移植材とその製造方法
JP5339347B2 (ja) * 2008-12-25 2013-11-13 独立行政法人物質・材料研究機構 医療用生体吸収性部材とその製造方法。
JP5517024B2 (ja) * 2009-02-02 2014-06-11 独立行政法人物質・材料研究機構 Mg基構造部材
WO2010101901A2 (en) 2009-03-02 2010-09-10 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8435281B2 (en) 2009-04-10 2013-05-07 Boston Scientific Scimed, Inc. Bioerodible, implantable medical devices incorporating supersaturated magnesium alloys
JP2011072617A (ja) * 2009-09-30 2011-04-14 Olympus Corp 移植材とその製造方法
TWI517865B (zh) * 2009-10-30 2016-01-21 阿卡斯塔克維京群島托特拉公司 以超純鎂為基底材質形成之生物可降解之植入性醫療器材
US20130001086A1 (en) * 2010-01-27 2013-01-03 Kimihiro Yamashita Metal oxide, metal material, biocompatible material, and method for producing metal oxide
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
GB201005031D0 (en) * 2010-03-25 2010-05-12 Magnesium Elektron Ltd Magnesium alloys containing heavy rare earths
EP2555811B1 (de) * 2010-04-06 2017-09-27 Boston Scientific Scimed, Inc. Endoprosthese
US9629873B2 (en) 2010-07-02 2017-04-25 University Of Florida Research Foundation, Inc. Bioresorbable metal alloy and implants made of same
US11491257B2 (en) 2010-07-02 2022-11-08 University Of Florida Research Foundation, Inc. Bioresorbable metal alloy and implants
KR101250700B1 (ko) * 2010-12-06 2013-04-03 성균관대학교산학협력단 생체분해성 마그네슘의 분해속도 제어방법 및 이를 이용한 의료기기용 생체분해성 마그네슘
TWI548427B (zh) 2010-12-21 2016-09-11 星瑟斯有限公司 含有生物可降解鎂系合金之醫療植入物及其製造方法
JP6027894B2 (ja) * 2011-01-24 2016-11-16 オリンパス株式会社 生分解性移植材およびその製造方法
WO2014028599A1 (en) * 2012-08-14 2014-02-20 Guo Yuebin A biodegradable medical device having an adjustable degradation rate and methods of making the same
JP2014132114A (ja) * 2012-12-07 2014-07-17 Nippon Sozai Kk 耐食性マグネシウム2元合金
US9155637B2 (en) * 2013-03-13 2015-10-13 Medtronic Vascular, Inc. Bioabsorbable stent with hydrothermal conversion film and coating
KR102246635B1 (ko) * 2013-03-15 2021-04-30 틱소매트 인코포레이티드 고강도 및 바이오-흡수가능한 마그네슘 합금
CN103272285B (zh) * 2013-05-24 2014-12-03 华南理工大学 可全降解生物材料及其制备方法
EP3011979A4 (de) * 2013-06-18 2017-02-15 Olympus Corporation Implantat für lebende organismen
WO2015003112A1 (en) * 2013-07-03 2015-01-08 University Of Florida Research Foundation, Inc. Biodegradable magnesium alloys, methods of manufacture thereof and articles comprising the same
DE102013214636A1 (de) * 2013-07-26 2015-01-29 Heraeus Medical Gmbh Bioresorbierbare Werkstoffverbunde, enthaltend Magnesium und Magnesiumlegierungen sowie Implantate aus diesen Verbunden
US9795427B2 (en) 2013-11-05 2017-10-24 University Of Florida Research Foundation, Inc. Articles comprising reversibly attached screws comprising a biodegradable composition, methods of manufacture thereof and uses thereof
US20160271301A1 (en) * 2013-11-08 2016-09-22 Siddarth Senthil-Kumar Hybrid Corrosion Inhibiting and Bio-Functional Coatings for Magnesium-Based Materials for Development of Biodegradable Metallic Implants
CN103757511B (zh) * 2013-12-27 2016-09-07 南通河海大学海洋与近海工程研究院 弥散强化型医用Mg-Zn-Ce-Ca-Mn合金及其制备方法
CN104790009B (zh) * 2014-01-16 2017-09-29 深圳富泰宏精密工业有限公司 金属与树脂的复合体的制备方法及由该方法制得的复合体
CN103882274B (zh) * 2014-03-18 2016-06-08 北京科技大学 生物医用可降解Mg-Zn-Zr-Sc合金及其制备方法
JP2015228906A (ja) * 2014-06-03 2015-12-21 オリンパス株式会社 骨接合用インプラント
JP2015229792A (ja) * 2014-06-05 2015-12-21 オリンパス株式会社 インプラントとその製造方法
JP6253528B2 (ja) * 2014-06-26 2017-12-27 オリンパス株式会社 インプラント
WO2016033312A1 (en) * 2014-08-27 2016-03-03 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Magnesium enhanced/induced bone formation
CA2969836C (en) 2014-12-12 2023-02-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Ultrahigh ductility mg-li based alloys for biomedical applications
WO2016118444A1 (en) 2015-01-23 2016-07-28 University Of Florida Research Foundation, Inc. Radiation shielding and mitigating alloys, methods of manufacture thereof and articles comprising the same
CN104593851A (zh) * 2015-02-12 2015-05-06 重庆大学 含细胞响应性耐腐蚀涂层的镁合金及其制备方法和应用
KR101722310B1 (ko) * 2015-02-17 2017-03-31 서울대학교산학협력단 생체 분해성 마그네슘 및 생체 분해성 마그네슘의 분해속도 제어방법
CN105411643B (zh) * 2015-12-17 2018-06-22 张韬 可降解医用弹簧圈
CN105671391B (zh) * 2016-01-19 2020-08-04 周倩 一种全降解镁合金及其制备方法
CN107773283A (zh) * 2016-08-31 2018-03-09 微创神通医疗科技(上海)有限公司 植入物、植入物制备方法及植入物系统
CN110191971A (zh) 2017-01-10 2019-08-30 不二轻金属株式会社 镁合金
CN106757251A (zh) * 2017-01-18 2017-05-31 东南大学 一种镁合金表面复合涂层的制备方法
WO2018139647A1 (ja) 2017-01-30 2018-08-02 株式会社日本医療機器技研 高機能生体吸収性ステント
CN108193111B (zh) * 2018-01-31 2019-10-18 中南大学 一种稀土镁合金阳极材料及其制备方法
CN114686739A (zh) 2018-07-09 2022-07-01 株式会社日本医疗机器技研 镁合金
CN109457130B (zh) * 2019-01-14 2020-11-20 兰州理工大学 一种高韧生物医用镁合金及其制备方法
JP7313612B2 (ja) * 2019-03-25 2023-07-25 学校法人 芝浦工業大学 高純度マグネシウム製の医療用インプラント及びその製造方法
CN110669971A (zh) * 2019-07-23 2020-01-10 东莞理工学院 一种医用3d打印镁合金材料及其制备方法
CN110747382B (zh) * 2019-12-11 2021-04-23 浙江工贸职业技术学院 一种超高压力作用下的Mg-Sc-X合金及其制备方法
IT201900023586A1 (it) * 2019-12-11 2021-06-11 Univ Degli Studi Di Palermo Metodo per il trattamento superficiale di leghe di magnesio per applicazioni biomedicali
CN111228577A (zh) * 2020-01-15 2020-06-05 太原科技大学 一种可短期降解医用镁合金及其制备方法
US20220370691A1 (en) 2021-05-10 2022-11-24 Cilag Gmbh International Bioabsorbable staple comprising mechanism for delaying the absorption of the staple
CN113322403A (zh) * 2021-06-03 2021-08-31 郑州大学 一种新型可降解高强韧镁合金骨钉材料及其制备方法
CN113667872A (zh) * 2021-08-25 2021-11-19 哈尔滨工程大学 一种Ho强化镁锂合金及其制备方法
CN113718145A (zh) * 2021-09-02 2021-11-30 景烽医用材料(浙江)有限公司 一种用于心血管疾病支架合金的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060052824A1 (en) * 2003-06-16 2006-03-09 Ransick Mark H Surgical implant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09176894A (ja) * 1995-12-21 1997-07-08 Sony Corp 表面処理方法
SE513481C2 (sv) * 1997-05-16 2000-09-18 Nobel Biocare Ab Implantatelement utfört av titan med en titanoxidyta modifierad med eloxidering
DE19731021A1 (de) * 1997-07-18 1999-01-21 Meyer Joerg In vivo abbaubares metallisches Implantat
SE514202C2 (sv) * 1999-05-31 2001-01-22 Nobel Biocare Ab På implantat till ben- eller vävnadsstruktur anordnat skikt samt sådant implantat och förfarande för applicering av skiktet
US7736687B2 (en) * 2006-01-31 2010-06-15 Advance Bio Prosthetic Surfaces, Ltd. Methods of making medical devices
JP4174153B2 (ja) * 1999-12-21 2008-10-29 昭和電工株式会社 Mg合金製押出品およびその製造方法
JP3768388B2 (ja) * 2000-07-18 2006-04-19 独立行政法人科学技術振興機構 生体用マグネシウム材料及びその製造方法
JP4911855B2 (ja) * 2001-10-17 2012-04-04 正 小久保 生体親和性に優れた骨代替材料の製造方法
DE10163106A1 (de) * 2001-12-24 2003-07-10 Univ Hannover Medizinische Implantate, Prothesen, Protheseteile, medizinische Instrumente, Geräte und Hilfsmittel aus einem halogenid-modifizierten Magnesiumwerkstoff
JP4212945B2 (ja) * 2003-04-24 2009-01-21 Necトーキン株式会社 機能性医療機器及びその製造方法
JP2005021420A (ja) * 2003-07-03 2005-01-27 Dentsply Sankin Kk 骨接合用プレート

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060052824A1 (en) * 2003-06-16 2006-03-09 Ransick Mark H Surgical implant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108431261A (zh) * 2015-12-28 2018-08-21 韩国机械研究院 具有优异的机械性能和耐腐蚀性的镁合金及其制造方法

Also Published As

Publication number Publication date
WO2007108450A1 (ja) 2007-09-27
EP1997522A1 (de) 2008-12-03
EP1997522B1 (de) 2015-05-13
JPWO2007108450A1 (ja) 2009-08-06
US20090131540A1 (en) 2009-05-21

Similar Documents

Publication Publication Date Title
EP1997522A4 (de) Biologisch abbaubares magnesiummaterial zur medizinischen verwendung
EP1997521A4 (de) Medizinisches material
EP2092892A4 (de) Ultraschallgerät
EP2014237A4 (de) Ultraschallgerät
IL192263A0 (en) Material
PT2029220E (pt) Sonda médica
HK1183225A1 (zh) 創傷敷料
EP1986554A4 (de) Gewebeklammer
EP2078536A4 (de) Medizinische vorrichtung
EP1997436A4 (de) Sonograph
GB0614988D0 (en) Autoclaves
GB0603926D0 (en) Syringes
EP2189118A4 (de) Ultraschallgerät
GB0616290D0 (en) Material
HK1147960A1 (en) Sterilisation indicator
GB0611223D0 (en) Biomedical materials
IL177979A0 (en) Multi-layered material
GB0625783D0 (en) Medicament
EP2060233A4 (de) Ultraschallgerät
GB0708169D0 (en) Surgical apparatus
EP2191850A4 (de) Gewebeverbindbares material zur medizinischen verwendung
EP2047804A4 (de) Ultraschallgerät
GB0615064D0 (en) Medicament
GB0615814D0 (en) Medicament
GB2438967B (en) Hopper unit

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20081008

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): CH DE FR GB LI

RBV Designated contracting states (corrected)

Designated state(s): CH DE FR GB LI

A4 Supplementary search report drawn up and despatched

Effective date: 20111006

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/00 20060101AFI20110929BHEP

Ipc: A61L 31/14 20060101ALI20110929BHEP

Ipc: A61L 31/08 20060101ALI20110929BHEP

Ipc: A61L 31/02 20060101ALI20110929BHEP

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20120731

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 602007041440

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: A61L0027000000

Ipc: A61L0027040000

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/30 20060101ALI20150108BHEP

Ipc: A61L 27/04 20060101AFI20150108BHEP

Ipc: A61L 31/14 20060101ALI20150108BHEP

Ipc: A61L 31/08 20060101ALI20150108BHEP

Ipc: A61L 31/02 20060101ALI20150108BHEP

Ipc: A61L 27/58 20060101ALI20150108BHEP

INTG Intention to grant announced

Effective date: 20150123

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): CH DE FR GB LI

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602007041440

Country of ref document: DE

Effective date: 20150625

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602007041440

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 10

26N No opposition filed

Effective date: 20160216

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160331

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160331

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 11

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20180322

Year of fee payment: 12

Ref country code: GB

Payment date: 20180321

Year of fee payment: 12

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20180330

Year of fee payment: 12

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602007041440

Country of ref document: DE

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20190319

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20191001

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190319

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20190331