EP1838595B1 - Folienbehälter - Google Patents

Folienbehälter Download PDF

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Publication number
EP1838595B1
EP1838595B1 EP05821609A EP05821609A EP1838595B1 EP 1838595 B1 EP1838595 B1 EP 1838595B1 EP 05821609 A EP05821609 A EP 05821609A EP 05821609 A EP05821609 A EP 05821609A EP 1838595 B1 EP1838595 B1 EP 1838595B1
Authority
EP
European Patent Office
Prior art keywords
film
weakening
film container
container according
films
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP05821609A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1838595A1 (de
Inventor
Sebastian Beyer
Johannes Geser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim International GmbH
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH, Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim International GmbH
Priority to EP11190894A priority Critical patent/EP2426064A1/de
Publication of EP1838595A1 publication Critical patent/EP1838595A1/de
Application granted granted Critical
Publication of EP1838595B1 publication Critical patent/EP1838595B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D2575/3209Details
    • B65D2575/3218Details with special means for gaining access to the contents
    • B65D2575/3227Cuts or weakening lines

Definitions

  • the invention relates to a film container according to the preamble of claim 1.
  • the film containers serve to protect pharmaceutical active ingredient formulations from environmental influences from the outside, which under certain circumstances may influence the pharmaceutical quality of the active substance formulation.
  • the DE 20 2004 003 781 U1 discloses a child-resistant rectangular package of two interconnected films, whose areal closure area includes at least one receiving space for a filling material.
  • a physical marking completely enclosed by the closure region is provided in the form of a change, in particular weakening or removal of a portion of the edge region.
  • the first mark is a cut or a line formed in the seal edge region closure region of the packaging formed from the films, which does not extend to the edge of the package, and provided as a second mark a line that crosses the first mark and at Buckling releases the first marking towards the outer contour towards tearing.
  • the closure area is widened in the area of an unsealed removal area to a tab which is bent so that the cut becomes part of the outer contour.
  • the opening of the packaging takes place by tearing off a packing end at the location of the cut.
  • a rectangular bag with a widened in a corner region sealing edge is shown, through which extends an obliquely to the outer contour aligned bending line from the right angles a cut or a punch for tearing the packaging.
  • the film container according to the invention has no additional tab or a relation to the receiving chamber changed connection area, as is known from the prior art, which is why it is relatively simple and therefore inexpensive to produce.
  • Rupture of the film container along the marking which is designed according to the invention as a weakening to remove a primary packaging, a powder, a liquid or other filling material, wherein the marking, for example, a partial weakening of the films, at least tearing of the films with a crack to ensures in the receiving chamber and present after bending at least on the outer edge of the film container.
  • a further marking which is also designed as a weakening, provided for the targeted buckling of the films in parallel and spaced from an outer edge of the film container.
  • the further marking may, for example, extend over the entire width of the film container and be printed as a line on one of the films.
  • the distance between the further marking and the associated outer edge is smaller than the distance from the receiving chamber.
  • the further marking separates the marking symmetrically, d. H. the mark has the same length on both sides of the further mark.
  • This variant is particularly preferred when tolerance reasons speak in particular in connection with a small length of the marking of, for example, 1 mm against the asymmetrical shape.
  • the tearing of the films for removal of the filling material is relatively easy to accomplish and on the other hand, the filling protected due to a relatively large area connection area from environmental influences.
  • the marking advantageously runs centrally to the receiving chamber.
  • the marking and the further marking expediently run at right angles to one another.
  • the marking is designed as a notch or cut.
  • the further marking is preferably a perforation. Due to these measures, the foil container can be opened without tools and the operations required for opening can be detected intuitively by an adult.
  • the two films are connected by a heat sealing lacquer.
  • the one film as the receiving chamber having carrier film and the other film is formed as a cover sheet.
  • the carrier film of the so-called blister is produced for example by deep drawing.
  • the films are formed as metal and / or plastic and / or paper foil. These materials can be present in multiple layers.
  • the support film consists for example on the side facing the contents of an approximately 60 micron thick layer of polyvinyl chloride (PVC), followed by an approximately 45 microns thick aluminum foil, which in turn with an approximately 25 micron thick film of an oriented polyamide (oPA) is connected.
  • PVC polyvinyl chloride
  • oPA oriented polyamide
  • the cover film may, for example, on the side facing the product from a about 5 microns (3 to 7 microns) thick heat sealing lacquer layer, for example, a commercially available polymer mixture based on acrylate, about 20 microns thick aluminum foil and an associated about 23 microns thick Foil consist of a polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the two films may also be identical or made of other materials, with a PET and a PVC / aluminum laminate per se are difficult to tear.
  • Aluminum foils also have the advantage that they may protect light-sensitive or UV-sensitive filling material from visible light and UV radiation.
  • a plurality of film containers are combined to form a blister card and singulated by intersecting perforations.
  • a blister card may comprise six foil containers, each foil container being separated by the intersecting perforations from adjacent foil containers.
  • the further marking runs parallel and at a distance to a perforation dividing the blister card in its middle. Accordingly, either first a separation of a film container from the blister card with subsequent buckling along the further marking for tearing according to the marking or, if necessary, after separation of the blister card in two halves buckling all film containers on one side of the blister card dividing perforation and the subsequent tearing a film container according to its marking required, the crack profile is considerably more difficult by the continuous edge of the respective opposite film container.
  • the film container according to the invention is, for example, for the packaging of pharmaceutical formulation containing Dabigatran etexilate, as described for example in the WHERE 03/074056 be described, suitable.
  • Trained as a blister film container 1 is part of a blister card 2, which is provided with intersecting perforations 3, 4 for separating the film container 1.
  • Each film container essentially comprises two films 5, one of which has a carrier film 9 having a capsule 8 filled with a pharmaceutical agent as a receiving chamber 6 and the other as a cover film 10 connected to the carrier film 9 by means of a heat sealing lacquer is formed, wherein the connecting portion of the two films 5, leaving the receiving chamber 6 extends over the entire surface.
  • the section 12 serves as a tear-open and lies after a buckling of the film container 1 along a parallel and spaced from the corresponding end-side outer edge 14 extending, designed as a perforation 15 further mark 16 at the corresponding outer edge 14.
  • the over the entire width of the film container 1 extending further mark 16 extends at right angles to the section 12 and separates it so asymmetrically that the course of the section 12 between the receiving chamber 6 and the further mark 16 longer than between the further mark 16 and the adjacent frontal outer edge 14 is.
  • the further marking 16 associated outer edge 14 opens into the centrally extending perforation 3 of the blister card 2, which is why tearing of the film container 1 for removal of the capsule 8 is possible only after a separation.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Table Devices Or Equipment (AREA)
  • Thermally Insulated Containers For Foods (AREA)
  • Wrappers (AREA)
  • Bag Frames (AREA)
  • Package Specialized In Special Use (AREA)
EP05821609A 2004-12-21 2005-12-16 Folienbehälter Active EP1838595B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11190894A EP2426064A1 (de) 2004-12-21 2005-12-16 Folienbehälter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004062864A DE102004062864A1 (de) 2004-12-21 2004-12-21 Folienbehälter
PCT/EP2005/056870 WO2006067096A1 (de) 2004-12-21 2005-12-16 Folienbehälter

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP11190894.3 Division-Into 2011-11-28

Publications (2)

Publication Number Publication Date
EP1838595A1 EP1838595A1 (de) 2007-10-03
EP1838595B1 true EP1838595B1 (de) 2012-04-04

Family

ID=35781441

Family Applications (2)

Application Number Title Priority Date Filing Date
EP05821609A Active EP1838595B1 (de) 2004-12-21 2005-12-16 Folienbehälter
EP11190894A Withdrawn EP2426064A1 (de) 2004-12-21 2005-12-16 Folienbehälter

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP11190894A Withdrawn EP2426064A1 (de) 2004-12-21 2005-12-16 Folienbehälter

Country Status (18)

Country Link
US (1) US7866474B2 (es)
EP (2) EP1838595B1 (es)
JP (1) JP4958902B2 (es)
KR (1) KR101237768B1 (es)
CN (1) CN101084155A (es)
AT (1) ATE552186T1 (es)
AU (1) AU2005318231B2 (es)
BR (1) BRPI0519727B1 (es)
CA (1) CA2592057C (es)
DE (1) DE102004062864A1 (es)
EA (1) EA012379B1 (es)
IL (1) IL184086A (es)
MX (1) MX2007007464A (es)
NO (1) NO338848B1 (es)
NZ (1) NZ556336A (es)
UA (1) UA87180C2 (es)
WO (1) WO2006067096A1 (es)
ZA (1) ZA200704195B (es)

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US20210395299A1 (en) 2018-10-29 2021-12-23 Huahai Us Inc. Novel dipeptide compounds and uses thereof
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CN114306245A (zh) 2020-09-29 2022-04-12 深圳市药欣生物科技有限公司 无定形固体分散体的药物组合物及其制备方法
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DE102004062864A1 (de) 2006-06-22
NO338848B1 (no) 2016-10-24
EP1838595A1 (de) 2007-10-03
MX2007007464A (es) 2007-07-19
AU2005318231B2 (en) 2011-08-25
JP4958902B2 (ja) 2012-06-20
NO20072669L (no) 2007-07-05
NZ556336A (en) 2010-12-24
WO2006067096A1 (de) 2006-06-29
CA2592057A1 (en) 2006-06-29
US7866474B2 (en) 2011-01-11
WO2006067096A8 (de) 2007-09-07
CN101084155A (zh) 2007-12-05
IL184086A0 (en) 2007-10-31
ATE552186T1 (de) 2012-04-15
IL184086A (en) 2015-08-31
EA200701208A1 (ru) 2007-12-28
AU2005318231A1 (en) 2006-06-29
KR20070094800A (ko) 2007-09-21
EA012379B1 (ru) 2009-10-30
CA2592057C (en) 2015-08-11
BRPI0519727A2 (pt) 2009-03-10
BRPI0519727B1 (pt) 2018-01-02
EP2426064A1 (de) 2012-03-07
UA87180C2 (ru) 2009-06-25
JP2008531428A (ja) 2008-08-14
KR101237768B1 (ko) 2013-03-08
US20060131204A1 (en) 2006-06-22
ZA200704195B (en) 2008-09-25

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