CN101084155A - 薄膜容器 - Google Patents

薄膜容器 Download PDF

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CN101084155A
CN101084155A CNA2005800439588A CN200580043958A CN101084155A CN 101084155 A CN101084155 A CN 101084155A CN A2005800439588 A CNA2005800439588 A CN A2005800439588A CN 200580043958 A CN200580043958 A CN 200580043958A CN 101084155 A CN101084155 A CN 101084155A
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塞巴斯蒂安·贝耶
约翰尼斯·格瑟
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Abstract

一种薄膜容器，包括两个特别是长方形的薄膜(5)，所述薄膜围绕它们的外周连接在一起形成容纳室(6)，其用于填充物(7)特别是活性物质的药物制剂，至少一个所述的薄膜(5)被提供位于连接区域内的用于将其撕开的目的标记(13)，其在薄膜(5)被弯曲后为暴露的，所述的标记(13)在所述薄膜容器(1)的两个相对的外缘(11)之间的中间延伸。

Description

薄膜容器
技术领域
本发明涉及具有两个特别是长方形的薄膜围绕它们的外周连接在一起形成容纳室的薄膜容器，其用于填充物特别是活性物质的药物制剂，至少一种所述的薄膜被提供用于将其撕开的目的，在连接区域内形成的标记，当所述膜弯曲时该标记为暴露的。
除了别的之外，所述薄膜容器被用于保护活性物质的药物制剂免于来自外部的环境的影响，所述影响可在某些情况下降低所述制剂的药物性质。
背景技术
在某些国家，为了使孩子难于接近特别是具有毒性效应的或当不当使用时其存在相对严重的健康风险的药物，用于对儿童安全的医药产品的包装的条例正在被考虑或者其已经存在。
DE 20 2004 003 781 U1公开了一种对儿童安全的长方形包装，其包括连接在一起的两层箔薄膜，其平接(flat connecting)区域包括至少一个用于填充物的容纳室。为了打开所述薄膜容器，提供改进形式的物理标记，特别是削弱的区域(weakened area)或除去边缘部分，其全部被密封区域包围。提供的第一个标记为在所述的薄膜形成的所述包装的密封区域中的切口或直线，该密封区域为密封的边缘部分形式，该第一个标记并没有延伸至所述包装的边缘，而提供的第二个标记为横穿第一个标记的直线，当其折痕时暴露朝着外部轮廓的用于撕开的目的的第一个标记。在非密封的除去部分区域加宽密封区域，形成标记，因此，当沿标记起折痕时所述切口变成外部轮廓的一部分。所述包装通过撕去在切口位置的包装的一端打开。而且，长方形的袋显示出具有一个密封边缘，其在一个角区域加宽，同时贯穿其中的为与横跨外部轮廓延伸的弯曲线，并且从那里发出一个直角状的用于撕开所述包装的切口或穿孔部分。
发明内容
本发明的问题是提供一个如上所述类型的被密封的薄膜容器，其对儿童安全，又可大面积打开，同时易于制备。
根据本发明，通过标记在所述薄膜容器的两个相对的外缘之间的中间延伸可解决该问题。
根据本发明的所述薄膜容器没有另外的标记或连接区域，其改进了如在现有技术构造中相关的与容纳室有关的部分，由于这个原因，其相对易于制备，因此相对便宜。在根据说明书上的指示有意折叠或折痕所述薄膜后，例如，沿着标记中间撕开所述薄膜容器，以便取出基本包装、粉剂、液体或其它的填充物，同时所述的标记例如所述薄膜消弱的部分确保了至少所述薄膜由于撕裂作用被撕开时其进入容纳室，并且在折痕后，所述薄膜消弱的部分至少存在在所述薄膜容器的外缘。
为了制备较容易的薄膜的折痕以便暴露标记，方便地提供另一个标记，用于控制所述薄膜的折痕平行于和距所述薄膜容器外缘一间隔。所述另一个标记可例如延伸至所述薄膜容器的全宽度，并将其印刷成在该薄膜之一上的直线。为了保护填充物，另一个标记到所述相联外缘的距离小于到所述容纳室的距离。
优选地，所述另一个标记不对称地分开了所述标记。换句话说，所述标记在另一个标记的一个侧面与另一个侧面具有不同的长度。优选地，所述容纳室和所述另一个标记之间的标记长度比所述另一个标记和相应外缘之间的标记长度长。因此，在一个方面，其相对易于撕开所述薄膜以便于取出填充物，另一方面，通过相对大面积连接区域保护所述填充物免于环境的影响。为了使其易于取出所述填充物，所述标记有利地在所述容纳室的中间延伸。方便地，将所述标记和另一个标记设置为互相成直角存在。
在第二个优选的实施方案中，所述另一个标记对称地分开了所述标记，即，所述标记在所述另一个标记的两侧具有相同的长度。当针对不对称形状的容差的原因特别地与短长度例如1mm的标记有关时，该变形是特别优选的。也在该实施方案中，在一个方面，为了取出所述填充物而撕开所述薄膜是相对易于进行的，在另一个方面，因为相对大面积连接区域，保护了所述填充物免于环境的影响。为了使其易于取出所述填充物，所述标记有利地在所述容纳室的中间延伸。方便地，将所述标记和另一个标记设置成互相为直角存在。
根据一个特征，所述标记为缺口或切口的形式。优选地，另一个标记为穿孔。由于这些措施，可以打开所述薄膜容器而不需要使用打开需要的工具和方法，所述措施可由成年人直观地掌握。
为了保护填充物不吸收通过连接区域渗透的水分，将两个薄膜通过热封漆连接在一起。
方便地，一个薄膜构建为承载所述容纳室的所述载体膜，另一个薄膜构建为覆盖膜。称之为泡膜的载体膜为由例如热成型形成的。优选地，所述膜构建为金属和/或塑料和/或纸薄膜。这些物质可以存在于几个层中。例如，在朝着填充物的一个面上，所述载体膜包括一个约60μm厚的聚氯乙烯(PVC)层，然后是一个约45μm厚的铝箔，其依次连接着一个约25μm厚的定向聚酰胺(oPA)膜。在朝着所述填充物的一个面上，所述覆盖膜例如可包括一个5μm(3至7μm)厚的热封漆层，例如市售可获得的丙烯酸酯基聚合物混合物，一个约20μm厚的铝膜和连接到其上的约23μm厚的聚对苯二甲酸乙二醇酯(PET)膜。当然，所述两个薄膜也可以完全相同或者由其他的物质制备，而PET和PVC/铝层本身难于撕开。
铝箔也具有下述优点，其保护光敏或UV敏感的填充物免于可见光和紫外辐射。
根据进一步的特征，多个薄膜容器结合形成泡卡，其可利用横断穿孔(intersecting perforations)来分离。一个泡卡可例如包括六个薄膜容器，每个薄膜容器利用横断穿孔与邻近的薄膜容器分离。
总地来说，为了使总体上对儿童而言更难于打开在泡卡中的薄膜容器，优选地设置另一个标记平行于并距沿着中心分开了泡卡的穿孔一段距离。因此，有必要地是，首先从泡卡分离薄膜容器，随后沿着另一个标记折痕，以便于沿着该标记将其撕开，或者任选地再将泡卡分成两等份后，在所述分开所述泡卡的穿孔的一个面上折痕所有的所述薄膜容器，然后沿着这个标记撕开铝箔容器，在这种情况下，基本上难于撕过相对薄膜容器的连续的边缘结构。
应当理解，上文提到的特征和其它的将在下文中更详细地描述的特征，其不仅可用在规定的组合中，还可用在其它组合中。本发明的范围仅仅由权利要求书来定义。
根据本发明的所述薄膜容器适于例如用于包装包含dabigatran etexilate的药物制剂，如例如在WO 03/074056中描述的。
附图说明
在下文中，本发明利用参照相关附图的示例性实施方案进行了更详细地描述，其中：
图1为一种根据本发明的薄膜容器的平面图，
图2为根据图1的所述薄膜容器的透视图，
图3为根据图1的所述薄膜容器的另一个透视图，和
图4为一种由多个根据图1的薄膜容器制成的泡卡的简图。
具体实施方式
所述泡形式的薄膜容器1为泡卡2的一部分，其具有用于分离所述薄膜容器1的横断穿孔3、4。每个薄膜容器主要包括两种薄膜5，其中的一种构建为包括用于填充物7，即装满药物活性物质的胶囊8的容纳室6的载体膜，而另一种构建为利用热封漆附着在所述载体膜上的覆盖膜10，两种薄膜5之间的连接区域延伸至其全部的表面，除了容纳室6之外。
在所述长方形薄膜容器1的两个平行纵向外缘11之间，在所述容纳室6的中间，在两种薄膜5的连接区域，设置切口12形式的标记13，其与末端面的相关外缘14和容纳室6都隔开一定距离。所述切口12起辅助撕开的作用，并且在所述薄膜容器1已经折痕后，沿着在相应外缘14上的另一个标记16出现，所述标记16为穿孔15的形式，平行于末端面上相应外缘14延伸并与其隔开一定距离。将延伸过所述薄膜容器1的全宽度的另一个标记16设置成与切口12成直角，并将其不对称地分开，使得在所述容纳室6和另一个标记16之间的切口12的轨迹比在另一个标记16和末端面上相邻的外缘14之间的轨迹部分长。外缘14与所述另一个标记16联合打开通往在泡卡2中间的延伸穿孔3，这就是为什么所述薄膜容器1只能在其已经分离后再被撕开，从而取出胶囊8。

Claims (16)

1.具有两个特别是长方形薄膜(5)的薄膜容器，所述长方形薄膜围绕它们的外周连接在一起形成容纳室(6)，其用于填充物(7)特别是活性物质的药物制剂，至少一个所述的薄膜(5)被提供用于将其撕开目的的标记(13)，其在连接区域内形成，在薄膜(5)被弯曲后该标记为暴露的，其特征在于所述的标记(13)在所述薄膜容器(1)的两个相对的外缘(11)之间沿中间延伸。
2.根据权利要求1的薄膜容器，其特征在于提供用于控制所述膜(5)弯曲的另一个标记(16)，其平行于所述薄膜容器(1)的外缘(14)并和其离开一定的距离。
3.根据权利要求1或2的薄膜容器，其特征在于另一个标记(16)与所述外缘(14)的距离小于与容纳室(6)的距离。
4.根据权利要求1至3中任一项的薄膜容器，其特征在于另一个标记(16)不对称地分开了所述的标记(13)。
5.根据权利要求1至4中任一项的薄膜容器，其特征在于在容纳室(6)和另一个标记(16)之间的所述标记(13)的轨迹比另一个标记(16)和相应外缘(14)之间的轨迹长。
6.根据权利要求1至3中任一项的薄膜容器，其特征在于另一个标记(16)对称地分开了所述标记(13)。
7.根据权利要求1至6中任一项的薄膜容器，其特征在于所述的标记(13)沿所述容纳室(6)的中间延伸。
8.根据权利要求1至7中任一项的薄膜容器，其特征在于所述的标记(13)和另一个标记(16)互相成直角延伸。
9.根据权利要求1至8中任一项的薄膜容器，其特征在于所述标记(13)为缺口或切口(12)的形式。
10.根据权利要求2至8中任一项的薄膜容器，其特征在于另一个标记(16)为穿孔(15)。
11.根据权利要求1至10中任一项的薄膜容器，其特征在于所述两个薄膜(5)为通过热封漆连接在一起。
12.根据权利要求1至11中任一项的薄膜容器，其特征在于一个薄膜(5)构建为包括容纳室(6)的载体膜(9)，另一个薄膜(5)构建为覆盖膜(10)。
13.根据权利要求1至12中任一项的薄膜容器，其特征在于所述薄膜(5)构建为金属和/或塑料和/或纸薄膜。
14.根据权利要求1至13中任一项的薄膜容器，其特征在于多个薄膜容器(1)结合形成泡卡(2)，其可利用横断穿孔(3，4)来分离。
15.根据权利要求2至14中任一项的薄膜容器，其特征在于另一个标记(16)平行穿孔(3)延伸并和其离开一定的距离，所述穿孔(3)在中间分开所述泡卡(2)。
16.根据权利要求1至15中任一项的薄膜容器，其特征在于所述的填充物包含含有dabigatran etexilate的药物制剂。
CNA2005800439588A 2004-12-21 2005-12-16 薄膜容器 Pending CN101084155A (zh)

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CN106458411A (zh) * 2014-06-04 2017-02-22 葛兰素集团有限公司 防儿童的包装件
CN107000913A (zh) * 2014-10-16 2017-08-01 葛兰素史克消费者保健有限公司 展示包
CN107848688A (zh) * 2015-08-04 2018-03-27 Ckd株式会社 泡罩片和泡罩包装机
CN107848688B (zh) * 2015-08-04 2020-02-11 Ckd株式会社 泡罩片和泡罩包装机

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KR20070094800A (ko) 2007-09-21
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AU2005318231A1 (en) 2006-06-29
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US7866474B2 (en) 2011-01-11
US20060131204A1 (en) 2006-06-22
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WO2006067096A8 (de) 2007-09-07
DE102004062864A1 (de) 2006-06-22
UA87180C2 (ru) 2009-06-25
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IL184086A (en) 2015-08-31
CA2592057C (en) 2015-08-11
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WO2006067096A1 (de) 2006-06-29
AU2005318231B2 (en) 2011-08-25
IL184086A0 (en) 2007-10-31
EA012379B1 (ru) 2009-10-30
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