EP1660017A4 - Aminosäure-prodrugs - Google Patents
Aminosäure-prodrugsInfo
- Publication number
- EP1660017A4 EP1660017A4 EP04816791A EP04816791A EP1660017A4 EP 1660017 A4 EP1660017 A4 EP 1660017A4 EP 04816791 A EP04816791 A EP 04816791A EP 04816791 A EP04816791 A EP 04816791A EP 1660017 A4 EP1660017 A4 EP 1660017A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- amino acid
- acid prodrugs
- prodrugs
- amino
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49133103P | 2003-07-29 | 2003-07-29 | |
PCT/US2004/024901 WO2005046575A2 (en) | 2003-07-29 | 2004-07-29 | Amino acid prodrugs |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1660017A2 EP1660017A2 (de) | 2006-05-31 |
EP1660017A4 true EP1660017A4 (de) | 2011-03-09 |
Family
ID=34590076
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04816791A Withdrawn EP1660017A4 (de) | 2003-07-29 | 2004-07-29 | Aminosäure-prodrugs |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1660017A4 (de) |
JP (2) | JP2007510621A (de) |
KR (3) | KR20130081319A (de) |
CN (1) | CN101123878A (de) |
AU (1) | AU2004289174B2 (de) |
CA (1) | CA2534342C (de) |
IL (1) | IL173382A0 (de) |
NZ (3) | NZ601772A (de) |
SG (2) | SG178721A1 (de) |
WO (1) | WO2005046575A2 (de) |
ZA (1) | ZA200600660B (de) |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7589233B2 (en) | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
EP1660017A4 (de) * | 2003-07-29 | 2011-03-09 | Signature R & D Holdings Llc | Aminosäure-prodrugs |
US8173840B2 (en) | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
CZ2006427A3 (cs) | 2003-12-29 | 2006-11-15 | Sepracor Inc. | Pyrrolové a pyrazolové inhibitory DAAO |
EP2754454A3 (de) * | 2004-01-07 | 2014-09-24 | Seikagaku Corporation | Derivaten von nicht-Steroide entzündungshemmende Arzneimittel |
US7241807B2 (en) | 2004-07-12 | 2007-07-10 | Xenoport, Inc. | Prodrugs of propofol, compositions and uses thereof |
PL1877098T3 (pl) * | 2005-05-05 | 2013-09-30 | Glaxosmithkline Ip Dev Ltd | Koniugaty estru alfa-aminokwasu z lekiem ulegające hydrolizie z udziałem karboksyloesterazy |
AU2006315638B2 (en) * | 2005-11-11 | 2013-02-21 | V. Ravi Chandran | Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements |
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US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
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CN116041259A (zh) * | 2023-01-13 | 2023-05-02 | 武汉科技大学 | 一种羟氯喹的衍生物及其制备方法 |
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EP1660017A4 (de) * | 2003-07-29 | 2011-03-09 | Signature R & D Holdings Llc | Aminosäure-prodrugs |
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2004
- 2004-07-29 EP EP04816791A patent/EP1660017A4/de not_active Withdrawn
- 2004-07-29 AU AU2004289174A patent/AU2004289174B2/en not_active Ceased
- 2004-07-29 KR KR1020137015399A patent/KR20130081319A/ko not_active Application Discontinuation
- 2004-07-29 CA CA2534342A patent/CA2534342C/en not_active Expired - Fee Related
- 2004-07-29 CN CNA2004800282229A patent/CN101123878A/zh active Pending
- 2004-07-29 NZ NZ601772A patent/NZ601772A/xx not_active IP Right Cessation
- 2004-07-29 JP JP2006522125A patent/JP2007510621A/ja active Pending
- 2004-07-29 SG SG2012005310A patent/SG178721A1/en unknown
- 2004-07-29 WO PCT/US2004/024901 patent/WO2005046575A2/en active Application Filing
- 2004-07-29 NZ NZ545570A patent/NZ545570A/xx not_active IP Right Cessation
- 2004-07-29 KR KR1020127022817A patent/KR20120116991A/ko not_active Application Discontinuation
- 2004-07-29 SG SG200805624-4A patent/SG145693A1/en unknown
- 2004-07-29 NZ NZ601780A patent/NZ601780A/xx not_active IP Right Cessation
- 2004-07-29 KR KR1020067002214A patent/KR20060073584A/ko active Search and Examination
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2005
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2006
- 2006-01-26 IL IL173382A patent/IL173382A0/en unknown
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2012
- 2012-10-01 JP JP2012219487A patent/JP2013035863A/ja active Pending
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US20030087803A1 (en) * | 2001-11-05 | 2003-05-08 | Yatvin Milton B. | Covalent conjugates of biologically-active compounds with amino acids and amino acid derivatives for targeting to physiologically-protected sites |
Also Published As
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SG178721A1 (en) | 2012-03-29 |
WO2005046575A3 (en) | 2007-10-04 |
SG145693A1 (en) | 2008-09-29 |
AU2004289174A1 (en) | 2005-05-26 |
KR20060073584A (ko) | 2006-06-28 |
NZ601772A (en) | 2012-10-26 |
AU2004289174B2 (en) | 2011-05-19 |
KR20130081319A (ko) | 2013-07-16 |
JP2013035863A (ja) | 2013-02-21 |
EP1660017A2 (de) | 2006-05-31 |
IL173382A0 (en) | 2006-06-11 |
AU2004289174A2 (en) | 2005-05-26 |
NZ601780A (en) | 2012-10-26 |
CA2534342C (en) | 2016-05-10 |
ZA200600660B (en) | 2007-04-25 |
CA2534342A1 (en) | 2005-05-26 |
CN101123878A (zh) | 2008-02-13 |
KR20120116991A (ko) | 2012-10-23 |
WO2005046575A2 (en) | 2005-05-26 |
NZ545570A (en) | 2012-07-27 |
JP2007510621A (ja) | 2007-04-26 |
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