EP1404291B1 - Wasserfreies ubichinon-konzentrat - Google Patents

Wasserfreies ubichinon-konzentrat Download PDF

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Publication number
EP1404291B1
EP1404291B1 EP02743249A EP02743249A EP1404291B1 EP 1404291 B1 EP1404291 B1 EP 1404291B1 EP 02743249 A EP02743249 A EP 02743249A EP 02743249 A EP02743249 A EP 02743249A EP 1404291 B1 EP1404291 B1 EP 1404291B1
Authority
EP
European Patent Office
Prior art keywords
weight units
coenzyme
concentrate
water
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP02743249A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1404291A1 (de
Inventor
Dariush Behnam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aquanova AG
Original Assignee
Aquanova AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7691172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1404291(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aquanova AG filed Critical Aquanova AG
Publication of EP1404291A1 publication Critical patent/EP1404291A1/de
Application granted granted Critical
Publication of EP1404291B1 publication Critical patent/EP1404291B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Confectionery (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP02743249A 2001-07-12 2002-06-29 Wasserfreies ubichinon-konzentrat Expired - Lifetime EP1404291B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10133305A DE10133305B4 (de) 2001-07-12 2001-07-12 Ubichinon Konzentrat
DE10133305 2001-07-12
PCT/EP2002/007195 WO2003007907A1 (de) 2001-07-12 2002-06-29 Wasserfreies ubichinon-konzentrat

Publications (2)

Publication Number Publication Date
EP1404291A1 EP1404291A1 (de) 2004-04-07
EP1404291B1 true EP1404291B1 (de) 2008-09-24

Family

ID=7691172

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02743249A Expired - Lifetime EP1404291B1 (de) 2001-07-12 2002-06-29 Wasserfreies ubichinon-konzentrat

Country Status (13)

Country Link
US (1) US7094804B2 (es)
EP (1) EP1404291B1 (es)
JP (1) JP2004534853A (es)
CN (1) CN1545406A (es)
AT (1) ATE409022T1 (es)
CA (1) CA2453473A1 (es)
DE (3) DE20122900U1 (es)
DK (1) DK1404291T3 (es)
ES (1) ES2315370T3 (es)
HK (1) HK1067297A1 (es)
MX (1) MXPA04000349A (es)
RU (1) RU2287981C2 (es)
WO (1) WO2003007907A1 (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20122900U1 (de) 2001-07-12 2009-12-03 Aquanova Ag Ubichinon Konzentrat
JP4234674B2 (ja) 2002-05-22 2009-03-04 ユニリーバー・ナームローゼ・ベンノートシヤープ 化粧品組成物を調製する方法、およびこの方法により調製した化粧品組成物
DE10243437A1 (de) * 2002-09-18 2004-04-29 Pm-International Ag Kosmetische Formulierung
US20060251637A1 (en) * 2003-03-11 2006-11-09 Toshinori Ikehara Oil-in-water type emulsion containing coenzyme q10 and process for producting the same
JP2006519796A (ja) * 2003-03-12 2006-08-31 ユニリーバー・ナームローゼ・ベンノートシヤープ 濃縮物からパーソナルケア組成物を製造する方法
US20070043106A1 (en) * 2005-08-18 2007-02-22 Dariush Behnam Alpha-lipoic acid concentrate
WO2006018301A1 (de) * 2004-08-18 2006-02-23 Aquanova German Solubilisate Technologies (Agt) Gmbh Liponsäure-konzentrat
JP5147239B2 (ja) * 2004-09-29 2013-02-20 三栄源エフ・エフ・アイ株式会社 コエンザイムｑ１０含有乳化組成物
AU2004326297B2 (en) * 2004-11-16 2008-08-07 Bioavailability, Inc. High concentration self-microemulsifying coenzyme Q10 preparations for nutritional use
DE102006010809B4 (de) * 2006-03-07 2009-10-22 Aquanova Ag Solubilisat eines Konservierungsmittels
US8491888B2 (en) * 2006-05-05 2013-07-23 Softgel Formulators, Inc. Highly absorbable coenzyme Q10 composition and method of producing same
MY153288A (en) * 2006-06-28 2015-01-29 Hovid Berhad An effective pharmaceutical carrier for poorly bioavailable drugs
JP5028885B2 (ja) * 2006-07-04 2012-09-19 大正製薬株式会社 ユビデカレノン含有自己乳化組成物
EP2066310B1 (de) * 2006-09-22 2012-04-18 Mivital AG Emulsionen enthaltend gummi arabicum
US20080145411A1 (en) * 2006-10-06 2008-06-19 Kaneka Corporation Composition of high absorbability for oral administration comprising oxidized coenzyme q10
WO2008138155A2 (de) * 2007-05-09 2008-11-20 Mivital Ag Emulsionsvorkonzentrate sowie micellare formulierungen enthaltend wurzelharz
US20090130198A1 (en) * 2007-11-21 2009-05-21 Innopharmax Inc. Pharmaceutical composition with enhanced bioavailability
WO2009117151A2 (en) * 2008-03-20 2009-09-24 Virun, Inc. Compositions containing non-polar compounds
WO2009117152A1 (en) 2008-03-20 2009-09-24 Virun, Inc. Emulsions including a peg-derivative of tocopherol
US8337931B2 (en) * 2008-06-23 2012-12-25 Virun, Inc. Compositions containing non-polar compounds
CH699449A2 (de) * 2008-08-27 2010-03-15 Mivital Ag Emulsionsvorkonzentrate sowie micellare Formulierungen enthaltend Glycerinfettsäureester.
US8445037B2 (en) * 2008-10-28 2013-05-21 A. M. Todd Company Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest
US9005608B2 (en) * 2009-03-24 2015-04-14 Adds Pharmaceuticals Llc Stabilized solubility-enhanced formulations for oral delivery
DE102009025215A1 (de) 2009-06-17 2010-12-30 Carl Zeiss Vision Gmbh Methode und Vorrichtung zur Ermittlung der habituellen Kopfhaltung
EP2544663B1 (en) 2010-03-12 2018-01-03 Berg LLC Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
WO2011119228A1 (en) * 2010-03-23 2011-09-29 Virun, Inc. Nanoemulsion including sucrose fatty acid ester
US8741373B2 (en) 2010-06-21 2014-06-03 Virun, Inc. Compositions containing non-polar compounds
MY183615A (en) 2011-06-17 2021-03-03 Berg Llc Inhalable pharmaceutical compositions
EP2811847B1 (en) 2012-02-10 2017-12-13 Virun, Inc. Beverage compositions containing non-polar compounds
EP2852379A4 (en) * 2012-05-22 2015-11-04 Laila Pharmaceuticals Pvt Ltd NEW NANOFORMULATIONS OF COMPOUNDS AND EXTRACTS DERIVED FROM HYDROPHOBIC, HIGHLY BIOAVAILABLE, WATER SOLUBLE AND EXTENDED RELEASE PLANTS
JP5722299B2 (ja) * 2012-12-07 2015-05-20 バイオアバイラビリティ，インク． 栄養学的に使用するための高濃度自己マイクロエマルジョン化コエンザイムｑ１０調製物
JP5999765B2 (ja) * 2012-12-07 2016-09-28 バイオアバイラビリティ，インク． 栄養学的に使用するための高濃度自己マイクロエマルジョン化コエンザイムｑ１０調製物
DE202012012130U1 (de) 2012-12-19 2014-03-21 Aquanova Ag Curcuminsolubilisat
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
AU2016324349A1 (en) * 2015-09-17 2018-02-15 Pharmako Biotechnologies Pty Limited Ubiquinone and ubiquinol compositions, and methods relating thereto
EP3290026A1 (en) 2016-09-06 2018-03-07 Athenion AG Method for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents
EP3511325A1 (en) * 2018-01-11 2019-07-17 MetrioPharm AG Method for solubilizing 5-amino-2,3-dihydro-1,4-phthalazinedione
EP3536332A1 (en) 2018-03-07 2019-09-11 Athenion AG Krill oil for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents
EP3919046A1 (en) 2020-06-02 2021-12-08 Athenion AG Method for solubilizing natural, endogenous and synthetic cannabinoids
EP4186497A1 (en) 2021-11-26 2023-05-31 Dorian Bevec Alpha lipoic acid, epigallocatechin 3-gallate, and curcumin as a medicament for the treatment of arthritis or sars-cov-2 infection
WO2023199908A1 (ja) * 2022-04-11 2023-10-19 株式会社ダイセル 乳化組成物の製造方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5581813A (en) * 1978-12-16 1980-06-20 Nisshin Flour Milling Co Ltd Composition containing coenzyme q10 and its perparation
JPS5618914A (en) 1979-07-25 1981-02-23 Eisai Co Ltd Ubidecarenone composition having good absorbability
DE3224619A1 (de) * 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Orale pharmazeutische zusammensetzung
JPS60199814A (ja) 1984-03-24 1985-10-09 Taisho Pharmaceut Co Ltd ユビデカレノン脂肪乳剤
EP0179583A1 (en) 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
JPS61221131A (ja) * 1985-03-28 1986-10-01 Eisai Co Ltd 吸収促進したユビデカレノン含有組成物
JPS62123113A (ja) 1985-11-22 1987-06-04 Green Cross Corp:The ユビデカレノン含有脂肪乳剤
IT1263840B (it) * 1993-03-30 1996-09-04 Giuseppe Furiosi Formulazioni orali di ubidecarenone in forma di capsule
US6056971A (en) * 1996-07-24 2000-05-02 Biosytes Usa, Inc. Method for enhancing dissolution properties of relatively insoluble dietary supplements and product incorporating same
DE19647352C2 (de) 1996-11-15 2000-06-29 Aqua Nova Getraenketechnologie Nicht alkoholisches Getränk mit einem Gehalt an Q 10
US6200550B1 (en) * 1998-12-11 2001-03-13 Q-Pharma, Inc. Oral care compositions comprising coenzyme Q10
US8753675B1 (en) * 2000-01-20 2014-06-17 Raj K. Chopra Reduced form of Coenzyme Q in high bioavailability stable dosage forms and related applications
DE10104847B4 (de) * 2000-06-09 2006-12-21 Aquanova German Solubilisate Technologies (Agt) Gmbh Tocopherol-Konzentrat und Verfahren zu seiner Herstellung
US6300377B1 (en) * 2001-02-22 2001-10-09 Raj K. Chopra Coenzyme Q products exhibiting high dissolution qualities
DE50100901D1 (de) 2001-04-12 2003-12-11 Vesifact Ag Baar Coenzym Q10 enthaltende Mikroemulsion-Prekonzentrate und Mikroemulsionen
DE20122900U1 (de) 2001-07-12 2009-12-03 Aquanova Ag Ubichinon Konzentrat

Also Published As

Publication number Publication date
MXPA04000349A (es) 2005-03-07
RU2004103975A (ru) 2005-03-27
DK1404291T3 (da) 2009-02-02
JP2004534853A (ja) 2004-11-18
DE10133305B4 (de) 2004-06-03
RU2287981C2 (ru) 2006-11-27
DE20122900U1 (de) 2009-12-03
CA2453473A1 (en) 2003-01-30
DE10133305A1 (de) 2003-02-13
CN1545406A (zh) 2004-11-10
US20030165438A1 (en) 2003-09-04
DE50212809D1 (de) 2008-11-06
EP1404291A1 (de) 2004-04-07
WO2003007907A1 (de) 2003-01-30
US7094804B2 (en) 2006-08-22
ES2315370T3 (es) 2009-04-01
HK1067297A1 (en) 2005-04-08
ATE409022T1 (de) 2008-10-15

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