EP1037815B2 - A method and a device for siliconising rubber stoppers - Google Patents

A method and a device for siliconising rubber stoppers Download PDF

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Publication number
EP1037815B2
EP1037815B2 EP98920777A EP98920777A EP1037815B2 EP 1037815 B2 EP1037815 B2 EP 1037815B2 EP 98920777 A EP98920777 A EP 98920777A EP 98920777 A EP98920777 A EP 98920777A EP 1037815 B2 EP1037815 B2 EP 1037815B2
Authority
EP
European Patent Office
Prior art keywords
emulsion
stoppers
pump
container
silicone oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP98920777A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1037815B1 (en
EP1037815A1 (en
Inventor
Jan-Olof Eriksson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Getinge Sterilization AB
Original Assignee
Getinge Sterilization AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20406759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1037815(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Getinge Sterilization AB filed Critical Getinge Sterilization AB
Priority to DK98920777T priority Critical patent/DK1037815T4/da
Publication of EP1037815A1 publication Critical patent/EP1037815A1/en
Application granted granted Critical
Publication of EP1037815B1 publication Critical patent/EP1037815B1/en
Publication of EP1037815B2 publication Critical patent/EP1037815B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C3/00—Apparatus in which the work is brought into contact with a bulk quantity of liquid or other fluent material
    • B05C3/02—Apparatus in which the work is brought into contact with a bulk quantity of liquid or other fluent material the work being immersed in the liquid or other fluent material

Definitions

  • the present invention relates to a method of treating rubber stoppers intended to seal packages containing sterile products, for instance medicinal preparations.
  • stoppers are used in order to stop such test tubes.
  • the stoppers are initially subjected to washing and rinsing treatments, followed by sterilisation and drying. Prior to the sterilisation step the stoppers are also treated with silicone to ensure that they do not adhere to one another when stored after the sterilisation step, but also to make the stoppers sufficiently pliable for convenient application to the test tubes one by one and for efficient sealing of the tubes.
  • stoppers are deposited on a vibrating table, known as a shaker.
  • a mist of silicone is sprayed onto the stoppers which are subsequently collected in containers or bags in which they are sterilised in an autoclave.
  • a thin silicone oil is mixed with water and an emulsifying agent is added to promote mixing.
  • an emulsion is formed which is pumped into a container holding stoppers therein.
  • the stoppers are siliconised, sterilised, and dried inside the container.
  • a method to siliconise devices using an emulsion of silicone oil and water together with an emulsifying agent is described in for example EP-0403400 and EP-0364375.
  • the object of the present invention is to provide a method of forming an emulsion from silicone and water without having to resort to the addition of any chemical substances, which emulsion may be used to efficiently siliconise rubber stoppers.
  • This object is achieved by means of the inventive method according to which silicone oil and water alone are mixed while being stirred with sufficient vigour to produce an emulsion, and the resulting emulsion is directed to a container in which the stoppers are stored and the siliconising process is carried out.
  • the invention likewise concerns a device for performing the method.
  • the features characterising the device are defined in the appended claims 3 and 4.
  • a dosage pump 4 is installed in a conduit 1 leading from a vessel 2 holding silicone oil 3. Downstream from the dosage pump 4 a shut-off valve 5 is mounted in the conduit 1.
  • the conduit 1 branches into a water-supply conduit 6 in which is likewise mounted a shut-off valve 7. Water supplied via the conduit 6 is mixed with dosed amounts of silicone oil 3 that are discharged from the pump 4 and transported through the conduit 1.
  • a dispersing pump 9 Downstream from the junction 8, where conduit 1 branches into conduit 6, a dispersing pump 9 is provided, and in a conduit 10 leading from pump 9 to a container 11 for storage of rubber stoppers to be siliconised are mounted a further shut-off valve 12 and a throttle valve 13.
  • the method in accordance with the invention is carried out in the following manner.
  • Water and silicone oil 3 in the desired proportions are pumped into the pump 9.
  • the dispersion carried out therein is sufficiently vigorous to produce an emulsion independently of whether the silicone oil is a high-viscosity or a low-viscosity oil.
  • the emulsion is then pumped into the container 11 wherein a mixture 14 of emulsion and rubber stoppers is formed. Siliconising of the rubber stoppers thereafter takes place, as a result of which the stoppers receive a thin silicone coating.
  • the throttle valve 13 is provided to allow variable throttling of the flow to the container 11. In this manner it becomes possible to regulate the emulsion mixing time inside the dispersing pump 9 in order to obtain optimum dispersing results.

Landscapes

  • Compositions Of Macromolecular Compounds (AREA)
  • Paints Or Removers (AREA)
  • Closures For Containers (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Sealing Material Composition (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
EP98920777A 1997-04-29 1998-04-23 A method and a device for siliconising rubber stoppers Expired - Lifetime EP1037815B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK98920777T DK1037815T4 (da) 1997-04-29 1998-04-23 En fremgangsmåde og en anordning til silikonisering af gummipropper

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9701602 1997-04-29
SE9701602A SE512231C2 (sv) 1997-04-29 1997-04-29 Metod och anordning för silikonisering av gummiproppar
PCT/SE1998/000738 WO1998049069A1 (en) 1997-04-29 1998-04-23 A method and a device for siliconising rubber stoppers

Publications (3)

Publication Number Publication Date
EP1037815A1 EP1037815A1 (en) 2000-09-27
EP1037815B1 EP1037815B1 (en) 2002-10-30
EP1037815B2 true EP1037815B2 (en) 2005-06-29

Family

ID=20406759

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98920777A Expired - Lifetime EP1037815B2 (en) 1997-04-29 1998-04-23 A method and a device for siliconising rubber stoppers

Country Status (6)

Country Link
EP (1) EP1037815B2 (ja)
JP (1) JP4190037B2 (ja)
AU (1) AU7354198A (ja)
DE (1) DE69809083T3 (ja)
SE (1) SE512231C2 (ja)
WO (1) WO1998049069A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114133608B (zh) * 2021-11-26 2023-02-03 湖北华强科技股份有限公司 一种提升丁基胶塞硅化均一度的硅化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5926129A (ja) * 1982-08-05 1984-02-10 Konishiroku Photo Ind Co Ltd 分散液滴の製造装置
FR2637606B1 (fr) * 1988-10-11 1990-12-14 Rhone Poulenc Chimie Dispersion aqueuse de silicone a base d'alcenyloxysilane reticulant en un elastomere par elimination de l'eau
FR2647798B1 (fr) * 1989-05-31 1991-09-13 Rhone Poulenc Chimie Dispersion aqueuse a base d'huiles silicones fonctionnalisees pouvant reticuler en un elastomere par elimination de l'eau
DE3931368A1 (de) * 1989-09-20 1991-03-28 Smeja Gmbh & Co Kg Reinigungs- und sterilisiermaschine fuer kleine gegenstaende, wie verschlusselemente von pharmazeutischen gefaessen
GB9519972D0 (en) * 1995-09-28 1995-11-29 Ag Patents Ltd Improved container stoppers

Also Published As

Publication number Publication date
JP2001522339A (ja) 2001-11-13
AU7354198A (en) 1998-11-24
SE9701602L (sv) 1998-10-30
DE69809083T3 (de) 2006-03-16
WO1998049069A1 (en) 1998-11-05
DE69809083D1 (de) 2002-12-05
EP1037815B1 (en) 2002-10-30
SE512231C2 (sv) 2000-02-14
SE9701602D0 (sv) 1997-04-29
JP4190037B2 (ja) 2008-12-03
DE69809083T2 (de) 2003-07-24
EP1037815A1 (en) 2000-09-27

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