EP0984692A4 - Nouveaux inhibiteurs d'angiogenese - Google Patents
Nouveaux inhibiteurs d'angiogeneseInfo
- Publication number
- EP0984692A4 EP0984692A4 EP98923719A EP98923719A EP0984692A4 EP 0984692 A4 EP0984692 A4 EP 0984692A4 EP 98923719 A EP98923719 A EP 98923719A EP 98923719 A EP98923719 A EP 98923719A EP 0984692 A4 EP0984692 A4 EP 0984692A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- angiogenesis inhibitors
- novel angiogenesis
- novel
- inhibitors
- angiogenesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4807697P | 1997-05-30 | 1997-05-30 | |
US48076P | 1997-05-30 | ||
GB9800681 | 1998-01-14 | ||
GBGB9800681.0A GB9800681D0 (en) | 1998-01-14 | 1998-01-14 | Novel angiogenesis inhibitors |
PCT/US1998/010590 WO1998054093A1 (fr) | 1997-05-30 | 1998-05-26 | Nouveaux inhibiteurs d'angiogenese |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0984692A1 EP0984692A1 (fr) | 2000-03-15 |
EP0984692A4 true EP0984692A4 (fr) | 2001-02-21 |
Family
ID=26312935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98923719A Withdrawn EP0984692A4 (fr) | 1997-05-30 | 1998-05-26 | Nouveaux inhibiteurs d'angiogenese |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0984692A4 (fr) |
JP (1) | JP2002501532A (fr) |
AU (1) | AU734009B2 (fr) |
CA (1) | CA2291709A1 (fr) |
WO (1) | WO1998054093A1 (fr) |
Families Citing this family (160)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000012486A1 (fr) | 1998-08-29 | 2000-03-09 | Astrazeneca Ab | Composes pyrimidiniques |
JP2002523497A (ja) | 1998-08-29 | 2002-07-30 | アストラゼネカ・アクチエボラーグ | ピリミジン化合物 |
EP1109555A4 (fr) * | 1998-08-31 | 2001-11-21 | Merck & Co Inc | Nouveaux inhibiteurs d'angiogenese |
GB9828511D0 (en) | 1998-12-24 | 1999-02-17 | Zeneca Ltd | Chemical compounds |
US6265403B1 (en) * | 1999-01-20 | 2001-07-24 | Merck & Co., Inc. | Angiogenesis inhibitors |
RU2262935C2 (ru) | 1999-02-10 | 2005-10-27 | Астразенека Аб | Производные хиназолина в качестве ингибиторов ангиогенеза |
GB9905075D0 (en) | 1999-03-06 | 1999-04-28 | Zeneca Ltd | Chemical compounds |
US6245759B1 (en) | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
WO2000059231A1 (fr) * | 1999-03-26 | 2000-10-05 | Microsoft Corporation | Re-agencement et mise en bloc de donnees images transformees par ondelettes |
GB9907658D0 (en) | 1999-04-06 | 1999-05-26 | Zeneca Ltd | Chemical compounds |
GB9919778D0 (en) | 1999-08-21 | 1999-10-27 | Zeneca Ltd | Chemical compounds |
UA74803C2 (uk) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування |
GB0004886D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004887D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004890D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004888D0 (en) | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0007371D0 (en) | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
US20020061897A1 (en) | 2000-03-30 | 2002-05-23 | Elliott Richard L. | Neuropeptide Y antagonists |
GB0016877D0 (en) | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Chemical compounds |
AU2001276536B2 (en) | 2000-08-09 | 2007-01-04 | Astrazeneca Ab | Quinoline derivatives having vegf inhibiting activity |
CN1252065C (zh) | 2000-08-09 | 2006-04-19 | 阿斯特拉曾尼卡有限公司 | 噌啉化合物 |
GB0021726D0 (en) | 2000-09-05 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
US7067520B2 (en) | 2000-11-17 | 2006-06-27 | Ishihara Sangyo Kaisha, Ltd. | Preventive or therapeutic medicines for diabetes containing fused-heterocyclic compounds or their salts |
WO2002059110A1 (fr) | 2000-12-21 | 2002-08-01 | Glaxo Group Limited | Composes chimiques |
HUP0302525A2 (hu) | 2001-01-05 | 2003-10-28 | Abgenix, Inc. | Az inzulinszerű növekedési faktor I receptor elleni ellenanyagok |
GB0103926D0 (en) | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
GB0113041D0 (en) | 2001-05-30 | 2001-07-18 | Astrazeneca Ab | Chemical compounds |
US6995171B2 (en) | 2001-06-21 | 2006-02-07 | Agouron Pharmaceuticals, Inc. | Bicyclic pyrimidine and pyrimidine derivatives useful as anticancer agents |
AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
JP2005524609A (ja) * | 2001-12-17 | 2005-08-18 | スミスクライン ビーチャム コーポレーション | ピラゾロピリダジン誘導体 |
PT1474420E (pt) | 2002-02-01 | 2012-05-10 | Astrazeneca Ab | Compostos de quinazolina |
CA2478050A1 (fr) | 2002-03-01 | 2003-09-12 | Pfizer Inc. | Derives indolyl-uree de thienopyridines utilises comme agents antiangiogeniques, et leurs methodes d'utilisation |
GB0205688D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
GB0205693D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
GB0205690D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
AU2003208479A1 (en) | 2002-03-09 | 2003-09-22 | Astrazeneca Ab | 4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity |
DE60314623T2 (de) | 2002-05-10 | 2008-02-28 | Smithkline Beecham Corp. | Substituierte pyrazolopyrimidine |
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UA77303C2 (en) | 2002-06-14 | 2006-11-15 | Pfizer | Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use |
CZ293015B6 (cs) * | 2002-10-25 | 2004-01-14 | Léčiva, A.S. | Způsob výroby N-ethyl-N-[3-(3-methyl-pyrazolo[1,5-a]pyrimidin-7-yl)-fenyl]-acetamidu (zaleplonu) |
CN1747950A (zh) | 2002-12-19 | 2006-03-15 | 美国辉瑞有限公司 | 用于治疗眼病的作为蛋白激酶抑制剂的2-(1h-吲唑-6-基氨基)-苯甲酰胺化合物 |
EP2476667B1 (fr) | 2003-02-26 | 2014-07-16 | Sugen, Inc. | Composés d'aminohétéroaryle utilisés en tant qu'inhibiteurs de protéine kinase |
EP1599482A4 (fr) | 2003-02-28 | 2008-10-01 | Teijin Pharma Ltd | Derives de pyrazolo 1,5-a pyrimidine |
EP1608652A1 (fr) * | 2003-03-31 | 2005-12-28 | Vernalis (Cambridge) Limited | Composes pyrazolopyrimidines et leur utilisation en medecine |
GB0311274D0 (en) | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
GB0311276D0 (en) | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
GB0314262D0 (en) | 2003-06-19 | 2003-07-23 | Univ Nottingham Trent | Novel compounds and methods of using the same |
DE602004017479D1 (de) | 2003-08-29 | 2008-12-11 | Pfizer | Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davon |
AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
DE10356579A1 (de) | 2003-12-04 | 2005-07-07 | Merck Patent Gmbh | Aminderivate |
WO2005063756A1 (fr) * | 2003-12-22 | 2005-07-14 | Sb Pharmco Puerto Rico Inc | Antagonistes du recepteur de crf et procedes correspondants |
GEP20084572B (en) | 2003-12-23 | 2008-12-25 | Pfizer | Novel quinoline derivatives |
GB0330002D0 (en) | 2003-12-24 | 2004-01-28 | Astrazeneca Ab | Quinazoline derivatives |
TW200528101A (en) | 2004-02-03 | 2005-09-01 | Astrazeneca Ab | Chemical compounds |
PL1786785T3 (pl) | 2004-08-26 | 2010-08-31 | Pfizer | Enancjomerycznie czyste związki aminoheteroarylowe jako kinazy białkowe |
WO2006033795A2 (fr) * | 2004-09-17 | 2006-03-30 | Wyeth | Methode d'utilisation de pyrazolo [1,5-a] pyrimidines substituees |
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CA2737597C (fr) | 2008-10-16 | 2017-03-14 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Anticorps entierement humains diriges contre un antigene associe au melanome de masse moleculaire elevee et leurs utilisations |
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WO2013050725A1 (fr) | 2011-10-04 | 2013-04-11 | King's College London | Anticorps ige anti-hmw-maa |
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- 1998-05-26 JP JP50079099A patent/JP2002501532A/ja active Pending
- 1998-05-26 AU AU75944/98A patent/AU734009B2/en not_active Ceased
- 1998-05-26 WO PCT/US1998/010590 patent/WO1998054093A1/fr not_active Application Discontinuation
- 1998-05-26 EP EP98923719A patent/EP0984692A4/fr not_active Withdrawn
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KIRKPATRICK W E ET AL: "3-HALO-5,7-DIMETHYLPYRAZOLO U1,5-APYRIMIDINES, A NONBENZODIAZEPINOID CLASS OF ANTIANXIETY AGENTS DEVOID OF POTENTIATION OF CENTRAL NERVOUS SYSTEM DEPRESSANT EFFECTS OF ETHANOL OR BARBITURATES", JOURNAL OF MEDICINAL CHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 20, no. 3, 1 March 1977 (1977-03-01), pages 386 - 393, XP000670076, ISSN: 0022-2623 * |
See also references of WO9854093A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2291709A1 (fr) | 1998-12-03 |
AU7594498A (en) | 1998-12-30 |
WO1998054093A1 (fr) | 1998-12-03 |
JP2002501532A (ja) | 2002-01-15 |
EP0984692A1 (fr) | 2000-03-15 |
AU734009B2 (en) | 2001-05-31 |
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