EP0822840A1 - Magnetfluidunterstützter elektromagnetischer antrieb für eine blutpumpe zur unterstützung oder zum teilweisen bis totalen ersatz des herzens - Google Patents
Magnetfluidunterstützter elektromagnetischer antrieb für eine blutpumpe zur unterstützung oder zum teilweisen bis totalen ersatz des herzensInfo
- Publication number
- EP0822840A1 EP0822840A1 EP97918007A EP97918007A EP0822840A1 EP 0822840 A1 EP0822840 A1 EP 0822840A1 EP 97918007 A EP97918007 A EP 97918007A EP 97918007 A EP97918007 A EP 97918007A EP 0822840 A1 EP0822840 A1 EP 0822840A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- heart
- magnetic fluid
- blood pump
- support
- electromagnetic drive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
- H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
- H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
- H01F1/442—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids the magnetic component being a metal or alloy, e.g. Fe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
- A61M60/178—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/196—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body replacing the entire heart, e.g. total artificial hearts [TAH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/424—Details relating to driving for positive displacement blood pumps
- A61M60/427—Details relating to driving for positive displacement blood pumps the force acting on the blood contacting member being hydraulic or pneumatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/89—Valves
- A61M60/892—Active valves, i.e. actuated by an external force
Definitions
- Magnetic fluid-assisted electromagnetic drive for a blood pump to support or to partially or completely replace the heart
- the invention is based on a magnetofluid-assisted electromagnetic drive for a blood pump for support or for partial or total replacement of the heart, which consists of one or more electromagnets and force-converting devices, as is known from US Pat. No. 4,650,485 .
- Electromagnetic Table systems consist of an electromagnet that mechanically squeezes a blood sack to promote the blood. Such an arrangement is described in detail in U.S. Patent 3,874,002. With the help of an electric motor, electromechanical systems generate a rotational movement which is converted into a pump movement. Electrohydraulic and electropneumatic systems are also known, in which a liquid or a gas is pumped into a chamber by means of a hydraulic pump or a compressor in order to move a flexible membrane for conveying the blood.
- Magnetofluids are stable dispersions with super-magnetic properties. They consist of single domain particles which are homogeneously distributed in selectable solvents with the aid of surface-active substances. The homogeneous distribution is maintained even in a strong magnetic field (gradient).
- the DD description 160532 describes such a magnetic fluid in detail. Magnetofluids with initial permeabilities up to 4 and saturation magnetizations up to 100 mT are known and described.
- the invention has for its object to provide a drive for a blood pump to support or to partially or completely replace the heart, the blood pump largely corresponds to the natural heart in terms of its weight and its energy density, and is particularly suitable for implantation, a reduction in the size of the overall system compared to known systems while improving the efficiency is made possible.
- a blood pump has a magnetofluid-assisted electromagnetic drive, which consists of one or more electromagnets and force-converting devices and in which the interspace of at least one electromagnetic circuit is completely or partially filled with magnetofluid, the poles having permanent magnetic properties .
- the essential idea of the invention is that the effect of the intermediate space is increased by the introduced magnetic fluid (ferrofluid, magnetic fluid) because of its higher permeability. This succeeds because the transition from the highly permeable inference to the fluid is one Force increase (Maxwellian tension).
- the negative pressure of the magnetic fluid can be used, which arises from the fact that on its free surface (for example to air), under the action of a magnetic field, force densities arise which are directed out of the magnetic fluid.
- the simplest version of the drive can be placed directly on a blood pump as a unicameral system. In more complex designs, two-chamber or four-chamber training is also possible. Executions in series are just as possible as a parallel arrangement.
- the drive can therefore be used in simple cardiovascular supports or can be used as a partial or even total replacement of the heart in a natural reproduction of the heart function.
- Fig. 1 cross section of the artificial heart drive when compressed
- Chamber, 2 cross section of the artificial heart drive during the suction process
- Figure 1 the principle of the drive is shown schematically for a single-chamber system in section.
- the chamber volume 10 is tightly enclosed by the chamber wall 9.
- the chamber wall 9 is designed as a flexible membrane and has inflow and outflow pipes 11 together with the ventricle 12.
- the flexibility of the chamber wall 9 allows the chamber volume 10 to be compressed by the drive 1 to 6.
- the necessary power transmission is through the direct contact of the upper chamber wall 9 with the guaranteed lower core half 2.
- the stationary parts are fixed by the housing 8, which is connected on the one hand to the lower chamber wall 9 and on the other hand to the upper core half 1.
- the two core halves 1 and 2 close in that the magnetic fluid 5 escapes from the magnetorheological contraction space.
- the springs 4 are tensioned for the expulsion phase.
- the chamber volume 9 is enlarged due to the elastic forces of the chamber wall 9 and, associated with this, as shown in FIG. 2, a suction process takes place via the opened inlet ventricle 12.
- the coils are fed from the outside through feed lines running in the channel 14.
- the specially developed magnetofluids with a saturation magnetization of 120 to 450 mT and initial permeabilities of 5 to 25 are advantageously used.
- These very high values for magnetofluids are achieved by using new magnetofluid compositions which contain ferromagnetic single domain particles (iron, cobalt or iron-cobalt alloys) in high concentration and which are used in low-viscosity solvents. agents are homogeneously distributed by means of surface-active compounds which are firmly anchored to the particle surface and are readily soluble in the respective solvent.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Mechanical Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Power Engineering (AREA)
- External Artificial Organs (AREA)
- Prostheses (AREA)
- Soft Magnetic Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19609281 | 1996-02-27 | ||
DE19609281A DE19609281C1 (de) | 1996-02-27 | 1996-02-27 | Magnetofluidunterstützter elektromagnetischer Antrieb für eine Blutpumpe zur Unterstützung oder zum teilweisen bis totalen Ersatz des Herzens |
PCT/DE1997/000441 WO1997031662A1 (de) | 1996-02-27 | 1997-02-27 | Magnetfluidunterstützter elektromagnetischer antrieb für eine blutpumpe zur unterstützung oder zum teilweisen bis totalen ersatz des herzens |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0822840A1 true EP0822840A1 (de) | 1998-02-11 |
Family
ID=7787799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97918007A Withdrawn EP0822840A1 (de) | 1996-02-27 | 1997-02-27 | Magnetfluidunterstützter elektromagnetischer antrieb für eine blutpumpe zur unterstützung oder zum teilweisen bis totalen ersatz des herzens |
Country Status (10)
Country | Link |
---|---|
US (1) | US6074365A (hu) |
EP (1) | EP0822840A1 (hu) |
JP (1) | JPH11504554A (hu) |
AU (1) | AU719915B2 (hu) |
BR (1) | BR9702122A (hu) |
CA (1) | CA2219490A1 (hu) |
DE (1) | DE19654864A1 (hu) |
EA (1) | EA000221B1 (hu) |
HU (1) | HUP9901479A3 (hu) |
WO (1) | WO1997031662A1 (hu) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2772971A1 (fr) * | 1997-12-23 | 1999-06-25 | Commissariat Energie Atomique | Actionneur a ferrofluide de proximite |
DE19806167A1 (de) * | 1998-02-14 | 1999-08-19 | Studiengesellschaft Kohle Mbh | Edelmetall-geschützte, antikorrosive magnetische Nanokolloide |
DE19821968A1 (de) * | 1998-05-18 | 1999-11-25 | Studiengesellschaft Kohle Mbh | Verfahren zur Modifizierung der Dispergiereigenschaften von metallorganisch-prästabilisierten bzw. -vorbehandelten Nanometallkolloiden |
US6251061B1 (en) | 1998-09-09 | 2001-06-26 | Scimed Life Systems, Inc. | Cardiac assist device using field controlled fluid |
AUPQ100699A0 (en) | 1999-06-17 | 1999-07-08 | Northern Sydney Area Health Service | An assist device for the failing heart |
AUPR333301A0 (en) * | 2001-02-23 | 2001-03-22 | Northern Sydney Area Health Service | Determining the volume of a normal heart and its pathological and treated variants by using dimension sensors |
DE10123151B4 (de) * | 2001-05-03 | 2007-07-19 | Berlin Heart Ag | Vorrichtung zur subkutanen Übertragung von Energie oder Daten |
DE10227779A1 (de) * | 2002-06-21 | 2004-01-08 | Studiengesellschaft Kohle Mbh | Monodisperse, magnetische Nanokolloide einstellbarer Größe und Verfahren zu deren Herstellung |
CN100344874C (zh) * | 2003-01-28 | 2007-10-24 | 清华大学 | 一种流体的传输方法及实现该方法的微型蠕动泵 |
TWI228101B (en) * | 2003-09-26 | 2005-02-21 | Ind Tech Res Inst | Micro pump using magnetic fluid or magneto-rheological fluid |
US7172551B2 (en) * | 2004-04-12 | 2007-02-06 | Scimed Life Systems, Inc. | Cyclical pressure coronary assist pump |
US7303581B2 (en) * | 2004-09-10 | 2007-12-04 | Peralta Eduardo J | Artificial heart using magnetohydrodynamic propulsionh |
US7539016B2 (en) * | 2005-12-30 | 2009-05-26 | Intel Corporation | Electromagnetically-actuated micropump for liquid metal alloy enclosed in cavity with flexible sidewalls |
US8128699B2 (en) * | 2009-03-13 | 2012-03-06 | Warsaw Orthopedic, Inc. | Spinal implant and methods of implantation and treatment |
ES2535255T3 (es) * | 2009-11-06 | 2015-05-07 | Fundación Tecnalia Research & Innovation | Dispositivo y procedimiento para la fijación de piezas |
US9157460B2 (en) * | 2012-06-05 | 2015-10-13 | Toyota Motor Engineering & Manufacturing North America, Inc. | Controlling a fluid flow with a magnetic field |
WO2017151562A1 (en) * | 2016-02-29 | 2017-09-08 | Lord Corporation | Additive for magnetorheological fluids |
DE102017128271A1 (de) * | 2017-08-01 | 2019-02-07 | Schwarzer Precision GmbH & Co. KG | Membranpumpe und Verfahren zur berührungslosen Betätigung der Membranen von mehreren Arbeitsräumen einer Membranpumpe |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE160532C (hu) * | ||||
US3768931A (en) * | 1971-05-03 | 1973-10-30 | Birch R | Magnetically actuated pump with flexible membrane |
US3874002A (en) * | 1972-09-07 | 1975-04-01 | Kurpanek W H | Pulsatile magneto-motive artificial heart |
US3912538A (en) * | 1974-01-15 | 1975-10-14 | United Technologies Corp | Novel composite fuel cell electrode |
GB2079381A (en) * | 1980-07-09 | 1982-01-20 | Bailey Arthur Raymond | Alternating current energised gas pumping device |
US4485024A (en) * | 1982-04-07 | 1984-11-27 | Nippon Seiko Kabushiki Kaisha | Process for producing a ferrofluid, and a composition thereof |
IT1203722B (it) * | 1983-12-30 | 1989-02-23 | Sala Berardino Della | Cuore artificiale rotale con azionamento elettromagnetico |
US4732706A (en) * | 1985-03-20 | 1988-03-22 | Ferrofluidics Corporation | Method of preparing low viscosity, electrically conductive ferrofluid composition |
IT1198253B (it) * | 1986-12-23 | 1988-12-21 | Sala Berardino Della | Protesi di cuore artificiale a ferrofluido perfezionata |
DE3709852A1 (de) * | 1987-03-24 | 1988-10-06 | Silica Gel Gmbh Adsorptions Te | Stabile magnetische fluessigkeitszusammensetzungen und verfahren zu ihrer herstellung und ihre verwendung |
US4992190A (en) * | 1989-09-22 | 1991-02-12 | Trw Inc. | Fluid responsive to a magnetic field |
US5129789A (en) * | 1990-04-23 | 1992-07-14 | Advanced Medical Systems, Inc. | Means and method of pumping fluids, particularly biological fluids |
US5147573A (en) * | 1990-11-26 | 1992-09-15 | Omni Quest Corporation | Superparamagnetic liquid colloids |
US5354488A (en) * | 1992-10-07 | 1994-10-11 | Trw Inc. | Fluid responsive to a magnetic field |
-
1996
- 1996-02-27 DE DE19654864A patent/DE19654864A1/de not_active Ceased
-
1997
- 1997-02-27 WO PCT/DE1997/000441 patent/WO1997031662A1/de not_active Application Discontinuation
- 1997-02-27 US US08/945,780 patent/US6074365A/en not_active Expired - Fee Related
- 1997-02-27 HU HU9901479A patent/HUP9901479A3/hu unknown
- 1997-02-27 AU AU26317/97A patent/AU719915B2/en not_active Ceased
- 1997-02-27 BR BR9702122A patent/BR9702122A/pt not_active Application Discontinuation
- 1997-02-27 JP JP9530518A patent/JPH11504554A/ja active Pending
- 1997-02-27 CA CA002219490A patent/CA2219490A1/en not_active Withdrawn
- 1997-02-27 EP EP97918007A patent/EP0822840A1/de not_active Withdrawn
- 1997-02-27 EA EA199700273A patent/EA000221B1/ru not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO9731662A1 * |
Also Published As
Publication number | Publication date |
---|---|
EA000221B1 (ru) | 1998-12-24 |
US6074365A (en) | 2000-06-13 |
WO1997031662A1 (de) | 1997-09-04 |
HUP9901479A2 (hu) | 1999-08-30 |
HUP9901479A3 (en) | 2001-06-28 |
CA2219490A1 (en) | 1997-09-04 |
EA199700273A1 (ru) | 1998-02-26 |
AU2631797A (en) | 1997-09-16 |
BR9702122A (pt) | 1999-01-26 |
DE19654864A1 (de) | 1997-08-28 |
AU719915B2 (en) | 2000-05-18 |
JPH11504554A (ja) | 1999-04-27 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 19971016 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE ES FR GB IT LI NL SE |
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17Q | First examination report despatched |
Effective date: 20010622 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
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18W | Application withdrawn |
Withdrawal date: 20011010 |