EP0521460A1 - Pointe de transfert et prélèvement - Google Patents
Pointe de transfert et prélèvement Download PDFInfo
- Publication number
- EP0521460A1 EP0521460A1 EP19920111057 EP92111057A EP0521460A1 EP 0521460 A1 EP0521460 A1 EP 0521460A1 EP 19920111057 EP19920111057 EP 19920111057 EP 92111057 A EP92111057 A EP 92111057A EP 0521460 A1 EP0521460 A1 EP 0521460A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- flow
- channel
- piercing
- shut
- flow channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012546 transfer Methods 0.000 title abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 56
- 230000000903 blocking effect Effects 0.000 claims description 20
- 238000009423 ventilation Methods 0.000 claims description 20
- 239000000126 substance Substances 0.000 description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- 238000000605 extraction Methods 0.000 description 7
- 238000007789 sealing Methods 0.000 description 4
- 238000013459 approach Methods 0.000 description 3
- 238000004891 communication Methods 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 241001631457 Cannula Species 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000013022 venting Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2058—Connecting means having multiple connecting ports
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2058—Connecting means having multiple connecting ports
- A61J1/2062—Connecting means having multiple connecting ports with directional valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2072—Venting means for internal venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2086—Filtering means for fluid filtration
Definitions
- the invention relates to a device, in particular for medical purposes, with a carrier plate and, connected thereto, diametrically arranged piercing spikes, through which two flow channels are guided.
- a device is referred to in technical terminology, for example, as a transfer spike or transfer device.
- the field of application for the present invention is in particular medical technology.
- a first container holding the liquid in particular a bottle or a bag
- a second Container in particular a container for receiving a substance to be dissolved, in particular a bottle or a bag.
- the medical device with the piercing spikes is inserted into the sealing plugs, each of which seals the two containers and is made of rubber or the like, i.e. the sealing plugs are pierced by means of the piercing spikes, so that a flow connection is created between the two containers via one of the two flow channels, while the other flow channel serves to equalize the pressure between the two containers.
- the liquid-receiving container is held upward, so that the liquid can pass into the container to be dissolved, the air in this container flows through the ventilation channel into the empty container.
- the device with the emptied container was separated from the now filled container and the dissolved substance was removed by means of a syringe provided with a cannula.
- the plug of the container had to be pierced by the cannula.
- the additional cannula with protective cap and separate packaging means that additional effort is required to remove the dissolved substance from the container.
- Additional manipulations using a separate cannula and inserting the same into the rubber stopper of the container deliver additional particles and fragments of the dissolved substance.
- the same cannula is used for the patient that was previously used to pierce the rubber stopper of the container.
- a device which has two piercing mandrels into which the two flow channels are integrated, this device consisting entirely of plastic.
- a device which has four Has piercing mandrels, with two piercing mandrels arranged diametrically to each other being assigned a flow channel for the liquid transfer or the venting.
- the spikes consist of metal, so that the spikes are cannulas.
- the device has a shut-off element cooperating with one of the flow channels, which releases the flow through the flow channel in an open position and blocks the flow through the flow channel in a blocking position, a liquid removal channel of the device in in the blocking position Flow connection with a section of the flow channel open to a piercing tip, and the liquid removal channel opens into a connecting piece.
- the mixing of different liquids that is to say at a point in time at which a connection of the two containers through two flow channels is no longer necessary, at least one flow channel of the shut-off element, wherein the shut-off element in the locked position establishes a flow connection between a section of the flow channel that is open to a puncture tip and a liquid removal channel of the device, through which the dissolved liquid can then be removed.
- the liquid removal channel itself opens into a connection piece, which is designed in particular as a connection canoe, for syringes or transfer systems. It goes without saying that the liquid extraction channel can also open into several connecting pieces.
- the advantage of the invention is therefore that a separate cannula with the problem of additional particles by pushing through the rubber stopper is not necessary. This saves additional packaging, disposal, handling and costs. At the same time, the invention precludes the user from using the same cannula for the rubber stopper as for the patient.
- shut-off element interacts only with one flow channel
- the other flow channel remains open in the locked position of the shut-off element.
- a backflow of the dissolved liquid from the container located at the top when the dissolved liquid is removed into the empty container below is excluded because the air in this container cannot flow out because of the section of the flow channel which is closed by the shut-off element and is assigned to the empty container.
- shut-off element also interacts with the other flow channel, the shut-off element opening the flow through the other flow channel in the open position and blocking the flow through the other flow channel in the blocking position, with an outward position in the blocking position open ventilation channel of the device in flow connection with a section of the other flow channel open to a puncture syringe of the associated piercing mandrel.
- the shut-off element can thus completely shut off the sections of the two flow channels opening into the lower, empty container and it takes place via the channel sections of the two flow channels assigned to the upper container holding the dissolved substance, as well as the liquid removal channel and the ventilation channel emptying container instead.
- the device expediently has two diametrically arranged piercing mandrels.
- the outlet openings of the one flow channel in the area of the piercing tip of the one piercing mandrel should be arranged at a distance from the piercing tip of the other piercing mandrel, and the outlet openings of the other flow channel should be arranged in the area of the piercing tip of the other piercing mandrel and spaced from the piercing tip of the one piercing mandrel.
- the liquid When the substance is dissolved, the liquid enters the flow channel from the upper container, whose outlet opening facing this container is lower, while the air from the lower container passes into the upper container through the outlet opening of the other flow channel located further up.
- the device should be connected to the two containers in such a way that after the substance has been loosened, i.e. before the dissolved substance has been removed, the liquid removal channel is assigned to the section of the flow channel whose outlet opening is lower than the outlet opening of the associated other flow channel.
- the piercing mandrels should extend perpendicular to the plane of the carrier plate, which is usually the main plane thereof.
- the shut-off element is designed as a slide element which is slidably mounted in the carrier plate, the slide element having two through bores which form channel sections of the two flow channels in the open position of the slide element, and furthermore the slide element forms the liquid removal channel and has the ventilation channel, which in the blocking position come into flow connection with the flow channel sections of a piercing mandrel.
- the sections of the flow channels leading to the lower, empty container are blocked in the blocking position of the blocking element and the liquid is withdrawn from the upper container or its container Ventilation exclusively via the channel sections of the two flow channels assigned to the upper container and the liquid extraction channel and the ventilation channel.
- a special embodiment of the invention provides that the slide element assumes its blocking position in the inserted position. If it is assumed that a syringe for removing the dissolved liquid is primarily connected to the connecting piece of the slide element and the connecting piece is oriented in the sliding direction of the slide element, the transfer of the slide element into its locked position can be accomplished by a pronounced insertion movement of the syringe into the connecting piece .
- a second embodiment of the inventive principle described at the outset provides that the shut-off element is designed as a tap with two T passages, with a first and a second outlet of the respective passage in the open position of the tap being in flow connection with one of the flow channels of the piercing mandrels and the third The outlet is closed by the carrier plate, and in the blocking position of the tap the first outlet of the respective passage is closed by the carrier plate and the second and the third outlet of the respective passage are in flow communication with the channel section of a piercing mandrel and the liquid extraction channel or the ventilation channel.
- the connection between the container to be emptied and the liquid extraction channel or the ventilation channel is effected by turning the valve into its locked position.
- the tap has two T-passages, but in principle it would be sufficient to provide one T-passageway which can be brought into operative connection with the flow channel serving for the removal of liquid, while the other passage is straight could be so that it blocks the associated flow channel when the valve is in the blocking position and thus does not allow ventilation of the container from which the dissolved substance can be removed.
- the dissolved substance would have to be removed from the assigned container against increasing negative pressure. A pressure equalization would be possible after removing the syringe from the connector after swiveling the container downwards beforehand.
- a third embodiment of the principle of the invention described in the introduction provides that a valve is integrated in the liquid removal channel, in particular a lip valve, which allows a flow through the liquid removal channel to the connecting piece when a negative pressure is applied to the connecting piece side.
- the liquid extraction channel is integrated into the shut-off element, which is also designed as a slide element, and when the slide element is in the blocking position, this interrupts the passage through the assigned flow channel, so that a flow path from the other section of this flow channel through the liquid removal channel and thus when a negative pressure is applied through the valve is possible is.
- the valve closes off the assigned flow channel in the area of the connecting piece.
- one of the flow channels has a branch which opens into a connecting piece which receives a conical extension of a Syringe or other disposable system is used, the device wall forming the flow channel at the level of the connecting piece on the opposite side thereof having a shoulder arranged substantially perpendicular to the flow path, which the approach introduced into the connecting piece contacts, such that the approach to the flow path shuts off a channel section and a flow connection between the flow path to the other Channel section and the syringe / disposable system opens, the connector being closed by a cap when the syringe is removed.
- a basic, preferred embodiment provides that a filter is integrated in those configurations in which there is a liquid extraction channel and / or a ventilation channel.
- Figures 1a, 1b and 1c illustrate the problem underlying the invention.
- a substance in a first container, the bottle 1 is to be dissolved using a liquid in the second container, the bottle 2, in the present case water, and the dissolved substance is then removed from the bottle 1 by means of the device 3 according to the invention.
- Figure 1a shows the device 3 in a highly simplified representation. It has a carrier plate 4, in which a shut-off element 5 designed as a slide is located in the region of the carrier plate 4 is shown in dashed lines, is displaceable in the direction of the double arrows B.
- the carrier plate 4 On the top and underside, the carrier plate 4 has two piercing mandrels 6 and 7 or 8 and 9 in the form of metal cannulas, the long piercing mandrel 6 being aligned with the short piercing mandrel 8 and the short piercing mandrel 7 being aligned with the long piercing mandrel 9 and thus also the flow channels formed by the piercing mandrels 6 to 9, which cannot be removed from this FIG.
- the shut-off element 5 also has two through bores 10 and 11, which are aligned with the flow channels of the piercing pins 6 and 8 or 7 and 9 in the extended position of the shut-off element representing the open position. Furthermore, the shut-off element 5 is provided with a liquid removal channel 12 and a ventilation channel 13 which, when the position representing the blocking position of the shut-off element 5 is inserted, come into connection with the section of the flow channel of the piercing mandrel 6 or the piercing mandrel 7 and the flow channel sections of the piercing mandrels 8 and 9 shut off.
- the arrangement described so far works as follows:
- the shut-off element 5 When the shut-off element 5 is in the open position, the bottle 1 with its bottle neck is inserted into a receptacle sleeve 14 connected to one side of the carrier plate 4, the piercing pins 8 and 9 penetrating a rubber stopper, not shown, of the bottle 1 on the other side of the carrier plate 4 is the receiving sleeve 15, the other bottle 2 is inserted with its bottle neck and the piercing pins 6 and 7 penetrate the rubber sealing plug of this bottle 2, which is not shown in more detail.
- the shut-off element 5 When the bottles 1 and 2 are plugged in, the shut-off element 5 is in its open position , This initial situation is shown in Figure 1a.
- the bottle 2 containing the water is held upwards, so that the water can pass through the short piercing mandrel 7, the through hole 11 and the piercing mandrel 9 into the lower bottle 1 containing the substance to be dissolved, while the bottle 1 corresponds to the filling state of the bottle in this air through the piercing mandrel B, the through hole 10 and the long piercing mandrel 6 into the bottle 2.
- the syringe attachment 17 of a dispensing syringe 18, which is only partially shown, is inserted into a connecting piece 16 in fluid communication with the liquid channel 12, the shut-off element being due to the insertion movement 5 is immediately transferred to the locked position.
- This state is shown in the illustration in FIG. 1b.
- the liquid removal channel 12 is thus in flow connection with the piercing mandrel B, while the ventilation channel 13 is connected to the piercing mandrel 9.
- the carrier plate 4 with the two bottles 1 and 2 is pivoted about the longitudinal axis of the dispensing syringe 18 by 180 °, so that the bottle 1, which is in water contains dissolved substance, is arranged above, and the empty bottle 2 below.
- the withdrawal syringe 18 is pulled out, the liquid containing the substance can be removed from the bottle 1 through the short piercing mandrel B and the liquid removal channel 12, and air can enter the bottle 1 through the ventilation channel 13 and the long piercing mandrel 9. This state is shown in Figure 1c.
- the disposable syringe 18 is to be replaced by another one, this can be done, for example, by moving the arrangement into the position according to FIG. 1b before removing the syringe and pivoting the position of FIG. 1c back after the next syringe has been attached.
- FIGS. 2a and 2b show a modified design of the device 3 according to the invention using a shut-off element 5 designed as a slide.
- the device 3 consists entirely of plastic.
- Two diametrically arranged piercing pins 19 and 20 are connected directly to the carrier plate 4, through which the two flow channels 21 and 22 are guided. These flow channels 21 are in the open position shown in FIG. 2a and 22 in flow connection with the through bores 10 and 11 of the shut-off element 5.
- the piercing mandrel 19 is inserted into the bottle 1 and the piercing mandrel 20 into the bottle 2, so that after the bottle 2 is upward is pivoted, the water can flow from the bottle 2 into the bottle 1 containing the substance to be dissolved.
- the shut-off element 5 is moved into its locked position and then the arrangement is pivoted through 180 °, so that the bottle 1 containing the water and the substance is arranged at the top.
- the position of the shut-off element 5 in this end position is shown in FIG. 2b, according to which in the area of the piercing mandrel 19 the flow channel 21 is in fluid communication with the liquid extraction channel 12 over the short channel length and the long channel length of the flow channel 22 via the ventilation channel 13 in the surrounding atmosphere lies.
- a liquid filter 23 integrated into the shut-off element 5 is provided, and accordingly an air filter 24 in the transition area between the ventilation channel 13 and the assigned section of the flow channel 22.
- the liquid removal channel 12 opens into a connecting piece 25 for the Withdrawal syringe 18, further into a connecting piece 26 for a transfer system, not shown, which can be connected to the device 3 and thus to the overall arrangement.
- the connecting pieces 25 and 26 can optionally be closed by means of caps 27.
- Two locking elements 28 and 29 arranged on the shut-off element 5 serve to fix the shut-off element in its open position or locked position, in that one of the locking elements 28 and 29 respectively engages in a recess 30 in the carrier plate.
- the device 3 in accordance with the embodiment described above, has two piercing pins 19 and 20, but there the shut-off element 5 is designed as a tap with two T passages 31 and 32.
- Each T passage 31 and 32 thus has three outputs 33, 34 and 35, respectively.
- the bore sections of the T passages 31 and 32 located between the outlets 33 and 34 connect them to the flow channels 21 and 22, respectively, so that when the piercing pins 19 are inserted into the bottles 1 and 2, respectively or 20 overflow the water in the bottle 2 into the bottle 1 and thus can dissolve the substance therein.
- the device 3 is shown in the relevant position of the shut-off element 5 in Figures 3a and 3c. To remove the dissolved substance, it is then only necessary to move the shut-off element 5 into the locked position and to pivot the arrangement by 180 ° in total.
- the blocking position is shown in FIGS. 3b and 3d, according to which the shut-off element 5 is rotated by 90 ° and thus a flow connection is formed between the section of the flow channel 21 assigned to the piercing mandrel 19 via the outlets 35 and 33 to the liquid removal channel 12.
- the device 3 again has the two piercing pins 19 and 20, with the flow channels 21 and 22.
- the shut-off element 5 designed as a slide is exclusively assigned to one flow channel, namely the flow channel 21.
- the essentially rotationally symmetrical shut-off element 5, which opens directly into the connecting piece 16 for the dispensing syringe 18, has a projection 36 on the side of the flow channel 21 facing the spike 20, which in the open position of the shut-off element 5 extends as far from the partition 37 between the two flow channels 21 and 22 arranged away is that the flow channels 21 and 22 can be flowed through unhindered when dissolving the substance.
- a lip valve 38 integrated into the shut-off element 5 and pointing towards the connecting piece 16 prevents water from entering the connecting piece 16 when the water is passed over to dissolve the substance.
- the dispensing syringe 18 is inserted with the syringe attachment 17 into the connecting piece 16, the shut-off element 5 being moved in the direction of the dividing wall 37 during the insertion movement until the projection 36 abuts the dividing wall 37 and the Closes passage through the flow channel 22 in the area of the piercing mandrel 20.
- a liquid filter 23 is integrated in the shut-off element 5.
- An anti-rotation device is not shown between the shut-off element 5 and a device attachment 40 serving to guide it.
- the carrier plate 4 extends essentially perpendicular to the plane of the drawing. Since in this embodiment no separate ventilation duct 13 is provided in the shut-off element 5, the device 3 is particularly suitable for non-rigid containers, for example plastic bags.
- FIGS. 5a and 5b also have two piercing pins 19 and 20 with two flow channels 21 and 22 corresponding to those according to FIGS. 4a and 4b.
- About half the length of the flow channel 22 opens into the connecting piece 16, which is closed with a cap.
- the partition 37 has on the side facing the connecting piece 16 at the level of the connecting piece 16 a shoulder arranged substantially perpendicular to the flow path.
- the syringe attachment 17 of the withdrawal syringe 18 contacts via an arc of its Front ring the above paragraph 41, with simultaneous sealing of the syringe neck 17 to the neck 16, so that the flow path is blocked by the area associated with the piercing mandrel 20 of the flow channel 21. While the liquid can flow unhindered through the piercing pins 19 and 20 when the dispensing syringe 18 is not inserted or when the connecting piece 16 is closed, while venting through the piercing pins at the same time, as shown in FIG Flow channel 21 are removed.
- the carrier plate 4 extends perpendicular to the plane of the drawing.
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4122221 | 1991-07-04 | ||
DE19914122221 DE4122221A1 (de) | 1991-07-04 | 1991-07-04 | Transfer- und entnahmespike |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0521460A1 true EP0521460A1 (fr) | 1993-01-07 |
EP0521460B1 EP0521460B1 (fr) | 1995-09-13 |
Family
ID=6435468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19920111057 Expired - Lifetime EP0521460B1 (fr) | 1991-07-04 | 1992-06-30 | Pointe de transfert et prélèvement |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0521460B1 (fr) |
AT (1) | ATE127679T1 (fr) |
DE (2) | DE4122221A1 (fr) |
Cited By (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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WO1995013785A1 (fr) * | 1993-11-16 | 1995-05-26 | Christian Eichler | Systeme de transvasement a usage medical ou pharmaceutique, par exemple pour transvaser une substance dans une solution |
WO1996029113A1 (fr) * | 1995-03-20 | 1996-09-26 | Medimop Medical Projects Ltd. | Dispositif de regulation de fluide |
WO1997020536A1 (fr) * | 1995-12-06 | 1997-06-12 | Gabriel Meyer | Dispositif pour la preparation d'une solution medicamenteuse reconstituee a partir de deux composants |
WO1999026581A1 (fr) * | 1997-11-24 | 1999-06-03 | Eurospital S.P.A. | Dispositif de transfert de fluide connectant deux recipients medicaux dans un systeme ferme |
FR2850015A1 (fr) * | 2003-01-22 | 2004-07-23 | Rvp Finance | Dispositif pour le transfert d'un liquide entre deux recipients |
US7491197B2 (en) | 2003-03-06 | 2009-02-17 | Csl Behring Gmbh | Fluid transfer device |
AU2004200893B9 (en) * | 2003-03-06 | 2010-04-15 | Csl Behring Gmbh | Transfer Device, in Particular for Medical Fluids |
AU2004200893B2 (en) * | 2003-03-06 | 2010-03-11 | Csl Behring Gmbh | Transfer Device, in Particular for Medical Fluids |
US7294122B2 (en) | 2003-07-17 | 2007-11-13 | Nipro Corporation | Transfer needle |
EP1498097A3 (fr) * | 2003-07-17 | 2005-02-16 | Nipro Corporation | Aiguille de transfert |
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WO2005120431A1 (fr) * | 2004-05-03 | 2005-12-22 | Sedat | Seringue pour interventions medicales et necessaire de reconstitution de substances extemporanees comportant une telle seringue |
FR2869533A1 (fr) * | 2004-05-03 | 2005-11-04 | Sedat Sa | Seringue pour interventions medicales et necessaire de reconstitution de substances extemporanees comportant une telle seringue |
US7896849B2 (en) | 2004-05-03 | 2011-03-01 | Sedat | Syringe for medical interventions and kit for reconstituting extemporaneous substances |
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EP2419071A2 (fr) * | 2009-04-14 | 2012-02-22 | Yukon Medical, LLC | Dispositif de transfert de fluide |
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USD923782S1 (en) | 2019-01-17 | 2021-06-29 | West Pharma. Services IL, Ltd. | Medication mixing apparatus |
US11918542B2 (en) | 2019-01-31 | 2024-03-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
USD954253S1 (en) | 2019-04-30 | 2022-06-07 | West Pharma. Services IL, Ltd. | Liquid transfer device |
US11484470B2 (en) | 2019-04-30 | 2022-11-01 | West Pharma. Services IL, Ltd. | Liquid transfer device with dual lumen IV spike |
US11786442B2 (en) | 2019-04-30 | 2023-10-17 | West Pharma. Services IL, Ltd. | Liquid transfer device with dual lumen IV spike |
USD956958S1 (en) | 2020-07-13 | 2022-07-05 | West Pharma. Services IL, Ltd. | Liquid transfer device |
USD1043974S1 (en) | 2022-04-22 | 2024-09-24 | West Pharma. Services IL, Ltd. | Liquid transfer device |
Also Published As
Publication number | Publication date |
---|---|
EP0521460B1 (fr) | 1995-09-13 |
DE59203648D1 (de) | 1995-10-19 |
DE4122221A1 (de) | 1993-03-18 |
ATE127679T1 (de) | 1995-09-15 |
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