EP0335145B1 - Récipient d'expédition en verre scellable pour matière biologique - Google Patents

Récipient d'expédition en verre scellable pour matière biologique Download PDF

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Publication number
EP0335145B1
EP0335145B1 EP89104150A EP89104150A EP0335145B1 EP 0335145 B1 EP0335145 B1 EP 0335145B1 EP 89104150 A EP89104150 A EP 89104150A EP 89104150 A EP89104150 A EP 89104150A EP 0335145 B1 EP0335145 B1 EP 0335145B1
Authority
EP
European Patent Office
Prior art keywords
container
glass
container according
infrared
absorbing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP89104150A
Other languages
German (de)
English (en)
Other versions
EP0335145A2 (fr
EP0335145A3 (en
Inventor
Reinhard Männl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schott Ruhrglas GmbH
Original Assignee
Schott Ruhrglas GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schott Ruhrglas GmbH filed Critical Schott Ruhrglas GmbH
Priority to AT89104150T priority Critical patent/ATE72396T1/de
Publication of EP0335145A2 publication Critical patent/EP0335145A2/fr
Publication of EP0335145A3 publication Critical patent/EP0335145A3/de
Application granted granted Critical
Publication of EP0335145B1 publication Critical patent/EP0335145B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/065—Rigid ampoules, e.g. glass ampoules

Definitions

  • the invention relates to a container according to the preamble of claim 1.
  • melting containers made of glass offer the primary advantage that after melting the material contained in them hermetically seals against the environment. Melting containers made of glass have so far been used predominantly for biological preservation and the like for biological material. For this reason and in order to exclude any effects of the container material on the biological material, glass types were used for the containers which are chemically less susceptible to attack and in particular are not attacked by the water-containing biological material even after long exposure times.
  • containers of this type offer the advantage that both disruptive effects on the biological material from the outside and damage due to inadvertent leakage of biological material to the outside, for example in the form of bacterial or viral contamination, are prevented.
  • the present invention has for its object to provide a melt shipping container made of glass, which is particularly suitable for the dispatch of biological material.
  • the container according to the invention has the particular advantage that it can be melted comfortably with focused incandescent light, which is known to contain a lot of infrared, so that the melting can easily be carried out even by trained personnel and / or mechanically with sufficiently uniform results without one open flame is required. Avoiding an open flame is often a necessity, or at least an important safety factor, at examination sites where biological preparations are obtained.
  • glasses are available as infrared-absorbing material which have a considerably lower processing temperature than normal container glasses, e.g. in the range of about 950-1000 ° C. This not only makes melting easier, it also greatly reduces the risk of inadmissible heating of the biological material.
  • an infrared-absorbing material is preferably used, which absorbs preferably in the near infrared.
  • An infrared-absorbing glass is preferably present as the infrared-absorbing material. This can easily be provided and processed in the melting area. In addition, there is the possibility that the container consists entirely of infrared-absorbing glass. This simplifies production and handling.
  • Infrared-absorbing glass has so far not been used for storing biological material, because it is not only more expensive than normal container glass, but also generally has a considerably lower hydrolytic resistance, so that there is a fear of interactions with the always water-containing biological material are. According to the invention, however, it has been recognized that the higher costs in comparison to the handling advantages of the container according to the invention play no role, and that the lower hydrolytic resistance of the infrared-absorbing glass does not yet appear to be a nuisance given the short residence times of the biological material in a shipping container.
  • the container according to the invention is particularly suitable as a standard shipping container for medical sample material that is dispatched daily in large quantities, e.g. from medical practices to examination laboratories.
  • FIG. 1 shows a melting shipping container 1 made of glass for a perishable biological material 3 filled into it, which can in particular be a medical sample material.
  • the container 1 has a tapered melting area 5, which consists of infrared-absorbing glass. As a result, the container can easily be carried in this melting area 5 focused incandescent light are melted.
  • This is indicated in Figure 1 by an incandescent lamp 7 with an elliptical reflector 9; as a result, a light beam 11 can be focused on the melting region 5 with the incandescent lamp.
  • the container 1 shown consists in one piece entirely of infrared-absorbing glass. This makes production easier than in embodiments in which an infrared-absorbing material, preferably made of glass, is provided only in the melting region 5, which is connected, preferably fused, to the other parts of the container, which consist of normal container glass.
  • Glass type No. 8516 from SCHOTT GLASWERKE, Mainz is particularly suitable as infrared-absorbing glass. It is also advantageous if the container, at least in the melting area, consists of a glass that has a low processing temperature, e.g. about 950-1000 ° C; this is the case with the aforementioned glass No. 8516 from SCHOTT GLASWERKE.
  • the container is designed as an examination container for use in examining the biological material.
  • the container shown has a non-circular shape in cross-section with two opposite, parallel, flat side walls 13 and 15.
  • the container can e.g. can be used as a cuvette for optical examinations, so that refilling is not necessary.
  • the container expediently has at least one predetermined breaking zone 17 at a sufficient distance from the melting region 5, which can be produced in various ways, for example by scratching, etching or, in a particularly advantageous manner, in the form of a prestressing zone which can be produced by local heat treatment of the container .
  • the container 1 expediently has at least one marking 19 which indicates the location of a predetermined breaking zone.
  • the melting zone 5 is expediently tapered, as shown.
  • Figure 2 shows the container 12 after melting.
  • the melting tip 21 produced thereby forms a hermetic seal.
  • FIG. 3 shows an embodiment in which a container 301, which otherwise can be designed like the container 1 shown in FIGS. 1 and 2, is encased with a coherent plastic layer 23. If the container 301 breaks, this plastic layer prevents the escape of biological material. In addition, a plastic layer that can be easily labeled can be used.

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Laminated Bodies (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Packages (AREA)
  • Glass Compositions (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Claims (12)

1. Récipient d'expédition scellable (1) en verre pour des substances biologiques facilement périssables, notamment pour des échantillons médicaux, qui présente une zone scellable par fusion (5), caractérisé en ce que la zone scellable par fusion comporte un matériau absorbant le rayonnement infrarouge.
2. Récipient selon la revendication 1, caractérisé en ce que le matériau absorbant le rayonnement infrarouge est un matériau de préférence absorbant dans l'infrarouge proche.
3. Récipient selon la revendication 1 ou 2, caractérisé en ce que le matériau absorbant le rayonnement infrarouge est un verre absorbant le rayonnement infrarouge.
4. Récipient selon la revendication 3, caractérisé en ce qu'il est entièrement constitué de verre absorbant le rayonnement infrarouge.
5. Récipient selon l'une des revendications précédentes, caractérisé en ce que, au moins dans la zone scellable par fusion, le récipient est en verre qui présente une température de travail plus faible.
6. Récipient selon la revendication 5, caractérisé en ce que la température de travail du verre est comprise entre 950 et 1000°C environ.
7. Récipient selon l'une des revendications 3 à 6, caractérisé en ce le verre absorbant le rayonnement infrarouge est le verre N° 8516 de la société SCHOTT GLASWERKE, Mayence.
8. Récipient selon l'une des revendications précédentes, caractérisé en ce qu'il est réalisé sous forme de récipient d'examen pouvant être utilisé lors de l'examen de la substance biologique.
9. Récipient selon l'une des revendications précédentes, caractérisé en ce qui présente au moins une zone de rupture (17).
10. Récipient selon la revendication 9, caractérisé en ce que la zone de rupture (17) est une zone de précontrainte.
11. Récipient selon la revendication 9 ou 10 caractérisé en ce qu'il comporte au moins un repère (19) indiquant une zone de rupture (17).
12. Récipient selon l'une des revendications précédentes caractérisé en ce qu'il est enveloppé d'une couche de matière plastique (23) continue.
EP89104150A 1988-03-31 1989-03-09 Récipient d'expédition en verre scellable pour matière biologique Expired - Lifetime EP0335145B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT89104150T ATE72396T1 (de) 1988-03-31 1989-03-09 Zuschmelz-versandbehaelter aus glas fuer biologisches material.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3810939 1988-03-31
DE3810939A DE3810939A1 (de) 1988-03-31 1988-03-31 Zuschmelz-versandbehaelter aus glas fuer biologisches material

Publications (3)

Publication Number Publication Date
EP0335145A2 EP0335145A2 (fr) 1989-10-04
EP0335145A3 EP0335145A3 (en) 1989-12-27
EP0335145B1 true EP0335145B1 (fr) 1992-02-05

Family

ID=6351127

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89104150A Expired - Lifetime EP0335145B1 (fr) 1988-03-31 1989-03-09 Récipient d'expédition en verre scellable pour matière biologique

Country Status (7)

Country Link
US (1) US5105957A (fr)
EP (1) EP0335145B1 (fr)
JP (1) JPH0296629A (fr)
AT (1) ATE72396T1 (fr)
DE (2) DE3810939A1 (fr)
ES (1) ES2030226T3 (fr)
GR (1) GR3003739T3 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413644B2 (en) * 1997-03-03 2002-07-02 R.J. Reynolds Tobacco Company Thin film structures for and method of sealing to glass
JP3902333B2 (ja) * 1998-06-24 2007-04-04 日本電気硝子株式会社 リードスイッチ用赤外線吸収ガラス
DE19940706A1 (de) * 1999-08-27 2001-03-08 Schott Glas Verschließbarer Glasbehälter mit einem umspritzten Kunststoffüberzug und Verfahren zu seiner Herstellung
EP1153895A4 (fr) * 1999-08-30 2004-04-14 Nippon Electric Glass Co Verre filtrant les rayons infrarouges pour commutateur a lames
US20030015274A1 (en) * 2001-06-29 2003-01-23 Mallman A. James Reflective hood for heat-shrinking film onto an open-topped container and method of using same
US20030021969A1 (en) * 2001-06-29 2003-01-30 Aloisi Robert J. Reflective heat-shrinking film
US7089718B2 (en) * 2002-06-10 2006-08-15 Green-Line Products, Inc. Apparatus for heat-shrinking film onto an open-topped container and method of using same
US20040035088A1 (en) * 2002-06-10 2004-02-26 Loeffler Herbert H. Container positioning device
US20040068968A1 (en) * 2002-06-10 2004-04-15 Biba Scott I. Modular rotational assembly
US7637500B2 (en) * 2006-03-28 2009-12-29 Hewlett-Packard Development Company, L.P. Advancing a media sheet along a media path
US7943189B2 (en) * 2007-10-26 2011-05-17 Lee Ferrell Food preservation packaging system
CN107464597B (zh) * 2017-08-30 2024-06-18 中广核研究院有限公司 强放射性工业钴源防泄漏封装结构及封装工艺

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE473289A (fr) *
US2517604A (en) * 1948-08-04 1950-08-08 Owens Illinois Glass Co Ampoule with breakable neck
DE845564C (de) * 1949-12-02 1952-08-04 Mix & Genest Ag Verfahren und Vorrichtung zur Erwaermung thermoplastischer Stoffe durch Waermestrahlen zum Zwecke der Warmbearbeitung
DE1105560B (de) * 1959-09-01 1961-04-27 Heinz Kock Dr Ampullenfoermiger Glasbehaelter zur Aufnahme von zersetzbaren oder unbestaendigen Fluessigkeiten
NL6510316A (fr) * 1965-08-06 1967-02-07
US3535070A (en) * 1966-02-03 1970-10-20 Owens Illinois Inc Method of inducing stress in glass containers and container made with a stressed zone
FR1549511A (fr) * 1967-10-31 1968-12-13
DE1796232B1 (de) * 1968-09-25 1971-08-05 Jenaer Glaswerk Schott & Gen Waermeabsorbierende und elektrisch hochisolierende verschmel zglaeser mit waermedehnungskoeffizienten zwischen 91,5 und 94,9 x 10 hoch 7 pro grad c (20 bis 300 grad c) zum ver schmelzen mit hilfe von heizstrahlen
GB1497190A (en) * 1975-01-30 1978-01-05 Jenaer Glaswerk Schott & Gen Glass compositions
US3961970A (en) * 1975-04-21 1976-06-08 Corning Glass Works Reed switch construction
US3949335A (en) * 1975-04-21 1976-04-06 Corning Glass Works Reed switch construction
JPS52147617A (en) * 1976-06-03 1977-12-08 Toyo Glass Co Ltd Colored frit
SE414486B (sv) * 1977-05-13 1980-08-04 Plm Ab Behallare for ljuskensligt gods
US4156626A (en) * 1977-07-18 1979-05-29 Souder James J Method and apparatus for selectively heating discrete areas of surfaces with radiant energy
FR2446263A1 (fr) * 1979-01-12 1980-08-08 Corning Glass Works Verre de scellement presentant un coefficient d'absorption eleve pour les rayons infra-rouges
DE2930912C2 (de) * 1979-07-30 1981-10-15 Jenaer Glaswerk Schott & Gen., 6500 Mainz Rißunanfällige, wärmeabsorbierende Verschmelzgläser im System SiO↓2↓-Al↓2↓O↓3↓-Na↓2↓O-PbO-Fe↓3↓O↓4↓ mit niedrigen Verarbeitungstemperaturen zur hermetischen Kapselung elektrotechnischer Bauteile
DE8601774U1 (de) * 1986-01-24 1986-06-12 Bünder Glas GmbH, 4980 Bünde Ampulle aus Glas
DE3615287A1 (de) * 1986-05-06 1987-11-12 Schott Ruhrglas Glasgefaess, insbesondere ampulle, und verfahren zur behandlung dieses glasgefaesses
US4826025A (en) * 1986-11-21 1989-05-02 Toppan Printing Co., Ltd. & Mect Corp. Ampoule package

Also Published As

Publication number Publication date
ATE72396T1 (de) 1992-02-15
EP0335145A2 (fr) 1989-10-04
US5105957A (en) 1992-04-21
EP0335145A3 (en) 1989-12-27
ES2030226T3 (es) 1992-10-16
GR3003739T3 (fr) 1993-03-16
DE58900811D1 (de) 1992-03-19
JPH0296629A (ja) 1990-04-09
DE3810939A1 (de) 1989-10-19

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