EP0335145B1 - Sealable glass shipping container for biological material - Google Patents

Sealable glass shipping container for biological material Download PDF

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Publication number
EP0335145B1
EP0335145B1 EP89104150A EP89104150A EP0335145B1 EP 0335145 B1 EP0335145 B1 EP 0335145B1 EP 89104150 A EP89104150 A EP 89104150A EP 89104150 A EP89104150 A EP 89104150A EP 0335145 B1 EP0335145 B1 EP 0335145B1
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EP
European Patent Office
Prior art keywords
container
glass
container according
infrared
absorbing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP89104150A
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German (de)
French (fr)
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EP0335145A3 (en
EP0335145A2 (en
Inventor
Reinhard Männl
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Schott Ruhrglas GmbH
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Schott Ruhrglas GmbH
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Priority to AT89104150T priority Critical patent/ATE72396T1/en
Publication of EP0335145A2 publication Critical patent/EP0335145A2/en
Publication of EP0335145A3 publication Critical patent/EP0335145A3/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/065—Rigid ampoules, e.g. glass ampoules

Definitions

  • the invention relates to a container according to the preamble of claim 1.
  • melting containers made of glass offer the primary advantage that after melting the material contained in them hermetically seals against the environment. Melting containers made of glass have so far been used predominantly for biological preservation and the like for biological material. For this reason and in order to exclude any effects of the container material on the biological material, glass types were used for the containers which are chemically less susceptible to attack and in particular are not attacked by the water-containing biological material even after long exposure times.
  • containers of this type offer the advantage that both disruptive effects on the biological material from the outside and damage due to inadvertent leakage of biological material to the outside, for example in the form of bacterial or viral contamination, are prevented.
  • the present invention has for its object to provide a melt shipping container made of glass, which is particularly suitable for the dispatch of biological material.
  • the container according to the invention has the particular advantage that it can be melted comfortably with focused incandescent light, which is known to contain a lot of infrared, so that the melting can easily be carried out even by trained personnel and / or mechanically with sufficiently uniform results without one open flame is required. Avoiding an open flame is often a necessity, or at least an important safety factor, at examination sites where biological preparations are obtained.
  • glasses are available as infrared-absorbing material which have a considerably lower processing temperature than normal container glasses, e.g. in the range of about 950-1000 ° C. This not only makes melting easier, it also greatly reduces the risk of inadmissible heating of the biological material.
  • an infrared-absorbing material is preferably used, which absorbs preferably in the near infrared.
  • An infrared-absorbing glass is preferably present as the infrared-absorbing material. This can easily be provided and processed in the melting area. In addition, there is the possibility that the container consists entirely of infrared-absorbing glass. This simplifies production and handling.
  • Infrared-absorbing glass has so far not been used for storing biological material, because it is not only more expensive than normal container glass, but also generally has a considerably lower hydrolytic resistance, so that there is a fear of interactions with the always water-containing biological material are. According to the invention, however, it has been recognized that the higher costs in comparison to the handling advantages of the container according to the invention play no role, and that the lower hydrolytic resistance of the infrared-absorbing glass does not yet appear to be a nuisance given the short residence times of the biological material in a shipping container.
  • the container according to the invention is particularly suitable as a standard shipping container for medical sample material that is dispatched daily in large quantities, e.g. from medical practices to examination laboratories.
  • FIG. 1 shows a melting shipping container 1 made of glass for a perishable biological material 3 filled into it, which can in particular be a medical sample material.
  • the container 1 has a tapered melting area 5, which consists of infrared-absorbing glass. As a result, the container can easily be carried in this melting area 5 focused incandescent light are melted.
  • This is indicated in Figure 1 by an incandescent lamp 7 with an elliptical reflector 9; as a result, a light beam 11 can be focused on the melting region 5 with the incandescent lamp.
  • the container 1 shown consists in one piece entirely of infrared-absorbing glass. This makes production easier than in embodiments in which an infrared-absorbing material, preferably made of glass, is provided only in the melting region 5, which is connected, preferably fused, to the other parts of the container, which consist of normal container glass.
  • Glass type No. 8516 from SCHOTT GLASWERKE, Mainz is particularly suitable as infrared-absorbing glass. It is also advantageous if the container, at least in the melting area, consists of a glass that has a low processing temperature, e.g. about 950-1000 ° C; this is the case with the aforementioned glass No. 8516 from SCHOTT GLASWERKE.
  • the container is designed as an examination container for use in examining the biological material.
  • the container shown has a non-circular shape in cross-section with two opposite, parallel, flat side walls 13 and 15.
  • the container can e.g. can be used as a cuvette for optical examinations, so that refilling is not necessary.
  • the container expediently has at least one predetermined breaking zone 17 at a sufficient distance from the melting region 5, which can be produced in various ways, for example by scratching, etching or, in a particularly advantageous manner, in the form of a prestressing zone which can be produced by local heat treatment of the container .
  • the container 1 expediently has at least one marking 19 which indicates the location of a predetermined breaking zone.
  • the melting zone 5 is expediently tapered, as shown.
  • Figure 2 shows the container 12 after melting.
  • the melting tip 21 produced thereby forms a hermetic seal.
  • FIG. 3 shows an embodiment in which a container 301, which otherwise can be designed like the container 1 shown in FIGS. 1 and 2, is encased with a coherent plastic layer 23. If the container 301 breaks, this plastic layer prevents the escape of biological material. In addition, a plastic layer that can be easily labeled can be used.

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  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Packages (AREA)
  • Laminated Bodies (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)

Abstract

A sealable glass shipping container for easily spoiled biological material, in particular medical sample material, is characterised in that the container has a sealing zone which possesses an infra red-absorbing material, in particular glass. <IMAGE>

Description

Die Erfindung betrifft einen Behälter nach dem Oberbegriff des Anspruchs 1.The invention relates to a container according to the preamble of claim 1.

Zuschmelz-Behälter aus Glas bieten für den Versand von leicht verderblichem biologischem Material, insbesondere medizinischem Probenmaterial, in erster Linie den Vorteil, daß sie nach dem Abschmelzen das in ihnen enthaltene Materials hermetisch gegen die Umgebung abdichten. Zuschmelz-Behälter aus Glas sind für biologisches Material bisher überwiegend für die Langzeit-Konservierung und dergleichen verwendet worden. Deshalb und um etwaige Einwirkungen des Behältermaterials auf das biologische Material auszuschließen, wurden für die Behälter Glassorten verwendet, die chemisch wenig angreifbar sind und insbesondere von dem wasserhaltigen biologischen Material auch nach langen Einwirkungszeiten nicht angegriffen werden.For the dispatch of perishable biological material, in particular medical sample material, melting containers made of glass offer the primary advantage that after melting the material contained in them hermetically seals against the environment. Melting containers made of glass have so far been used predominantly for biological preservation and the like for biological material. For this reason and in order to exclude any effects of the container material on the biological material, glass types were used for the containers which are chemically less susceptible to attack and in particular are not attacked by the water-containing biological material even after long exposure times.

Ein Verfahren um einen solchen Behälter herzustellen, ist in der FR-A-1549511 beschrieben.A method for producing such a container is described in FR-A-1549511.

In neuerer Zeit ist erkannt worden, daß es zweckmäßig ist, Zuschmelzbehälter aus Glas auch beim Versand von biologischen Proben zu verwenden und den Mehraufwand für das Zuschmelzen und das zerstörende Öffnen der Behälter in Kauf zu nehmen; derartige Behälter bieten nämlich wegen des schon erwähnten hermetischen Abschlusses gegen die Umgebung den Vorteil, daß sowohl störende Einwirkungen von außen auf das biologische Material als auch Schäden durch unbeabsichtigten Austritt von biologischem Material nach außen, beispielsweise in Form einer bakteriellen oder viralen Kontaminierung, verhindert werden.It has recently been recognized that it is expedient to use melting containers made of glass even when sending biological samples and to accept the additional expenditure for melting and the destructive opening of the containers; Because of the hermetic seal against the environment already mentioned, containers of this type offer the advantage that both disruptive effects on the biological material from the outside and damage due to inadvertent leakage of biological material to the outside, for example in the form of bacterial or viral contamination, are prevented.

Die allgemeine Einführung derartiger Behälter für den Versand von biologischem Material, insbesondere medizinischem Probenmaterial, ist jedoch bisher durch Handhabungsnachteile behindert worden. So ist es für wenig Geübte nicht einfach, einen Glasbehälter abzuschmelzen und dadurch zu verschließen; denn es sind dazu hohe Temperaturen und die Anwendung entsprechend leistungsfähiger Heizquellen, in der Regel Gebläseflammen, erforderlich. Auch wird beim Abschmelzen oft das in dem Behälter befindliche biologische Material, das seiner Natur nach wärmeempfindlich ist, unzulässig hoch erwärmt und dadurch beschädigt oder gar abgetötet.The general introduction of such containers for the dispatch of biological material, in particular medical sample material, has so far been hampered by handling disadvantages. So it is not easy for the inexperienced to melt a glass container and thereby seal it; because this requires high temperatures and the use of correspondingly powerful heat sources, usually fan flames. Also when melting, that is often in biological material in the container, which is inherently sensitive to heat, heated to an unacceptably high level and thereby damaged or even killed

Die vorliegende Erfindung geht von der Aufgabe aus, einen Zuschmelz-Versandbehälter aus Glas zu schaffen, der für den Versand von biologischem Material besonders geeignet ist.The present invention has for its object to provide a melt shipping container made of glass, which is particularly suitable for the dispatch of biological material.

Nach der Erfindung wird diese Aufgabe mit dem Behälter nach dem Anspruch 1 gelöst.According to the invention, this object is achieved with the container according to claim 1.

Der erfindungsgemäße Behälter bietet insbesondere den Vorteil, daß er bequem mit fokussiertem Glühlicht, das bekanntlich viel Infrarot enthält, zugeschmolzen werden kann, so daß das Zuschmelzen leicht auch von nur angelerntem Personal und/oder maschinell mit ausreichend gleichmäßigen Ergebnissen durchgeführt werden kann, ohne daß eine offene Flamme erforderlich ist. Das Vermeiden einer offenen Flamme ist an Untersuchungsorten, wo biologische Präparate gewonnen werden, oft eine Notwendigkeit oder zumindest ein bedeutender Sicherheitsfaktor. Hinzu kommt, daß als infrarot-absorbierendes Material Gläser erhältlich sind, die eine erheblich niedrigere Verarbeitungstemperatur als normale Behältergläser haben, z.B. im Bereich von etwa 950-1000°C. Dadurch wird nicht nur das Zuschmelzen erleichtert, sondern auch die Gefahr einer unzulässigen Erwärmung des biologischen Materials stark verringert. Entsprechend der spektralen Leistungsverteilung bei Glühlampenlicht wird vorzugsweise ein infrarot-absorbierendes Material verwendet, das bevorzugt im nahen Infrarot absorbiert.The container according to the invention has the particular advantage that it can be melted comfortably with focused incandescent light, which is known to contain a lot of infrared, so that the melting can easily be carried out even by trained personnel and / or mechanically with sufficiently uniform results without one open flame is required. Avoiding an open flame is often a necessity, or at least an important safety factor, at examination sites where biological preparations are obtained. In addition, glasses are available as infrared-absorbing material which have a considerably lower processing temperature than normal container glasses, e.g. in the range of about 950-1000 ° C. This not only makes melting easier, it also greatly reduces the risk of inadmissible heating of the biological material. According to the spectral power distribution in incandescent light, an infrared-absorbing material is preferably used, which absorbs preferably in the near infrared.

Vorzugsweise liegt als infrarot-absorbierendes Material ein infrarot-absorbierendes Glas vor. Dieses kann leicht in dem Zuschmelzbereich vorgesehen und verarbeitet werden. Außerdem ergibt sich dabei die Möglichkeit, daß der Behälter ganz aus infrarot-absorbierendem Glas besteht. Das vereinfacht Fertigung und Handhabung.An infrared-absorbing glass is preferably present as the infrared-absorbing material. This can easily be provided and processed in the melting area. In addition, there is the possibility that the container consists entirely of infrared-absorbing glass. This simplifies production and handling.

Infrarot-absorbierendes Glas ist bisher zum Aufbewahren von biologischem Material nicht verwendet worden, weil es im Vergleich zu normalem Behälterglas nicht nur teurer ist, sondern auch in der Regel eine erheblich geringere hydrolytische Beständigkeit aufweist, so daß Wechselwirkungen mit dem stets wasserhaltigen biologischen Material zu befürchten sind. Erfindungsgemäß ist jedoch erkannt worden, daß die höheren Kosten im Vergleich zu den Handhabungsvorteilen des erfindungsgemäßen Behälters keine Rolle spielen, und daß bei den kurzen Verweilzeiten des biologischen Materials in einem Versandbehälter die geringere hydrolytische Beständigkeit des infrarot-absorbierenden Glases noch nicht störend in Erscheinung tritt.Infrared-absorbing glass has so far not been used for storing biological material, because it is not only more expensive than normal container glass, but also generally has a considerably lower hydrolytic resistance, so that there is a fear of interactions with the always water-containing biological material are. According to the invention, however, it has been recognized that the higher costs in comparison to the handling advantages of the container according to the invention play no role, and that the lower hydrolytic resistance of the infrared-absorbing glass does not yet appear to be a nuisance given the short residence times of the biological material in a shipping container.

Der erfindungsgemäße Behälter ist wegen der beschriebenen Vorteile besonders als Standard-Versandbehälter für medizinisches Probenmaterial geeignet, das täglich in großen Mengen versandt wird, z.B. von ärztlichen Praxen zu Untersuchungslaboratorien.Because of the advantages described, the container according to the invention is particularly suitable as a standard shipping container for medical sample material that is dispatched daily in large quantities, e.g. from medical practices to examination laboratories.

Die Erfindung wird im folgenden anhand von Ausführungsbeispielen in Verbindung mit der Zeichnung näher beschrieben.

  • Figur 1 ist eine schematische perspektivische Ansicht eines erfindungsgemäßen Behälters vor dem Zuschmelzen.
  • Figur 2 ist eine der Figur 1 entsprechende Ansicht des Behälters nach dem Zuschmelzen.
  • Figur 3 ist ein schematischer Querschnitt durch eine andere Ausführungsform.
The invention is described below with reference to exemplary embodiments in conjunction with the drawing.
  • Figure 1 is a schematic perspective view of a container according to the invention before melting.
  • Figure 2 is a view corresponding to Figure 1 of the container after melting.
  • Figure 3 is a schematic cross section through another embodiment.

Figur 1 zeigt einen Zuschmelz-Versandbehälter 1 aus Glas für ein in ihn eingefülltes leicht verderbliches biologisches Material 3, bei dem es sich insbesondere um ein medizinisches Probenmaterial handeln kann. Der Behälter 1 weist einen verjüngten Zuschmelzbereich 5 auf, der aus infrarot-absorbierendem Glas besteht. Dadurch kann der Behälter in diesem Zuschmelzbereich 5 leicht mit fokussiertem Glühlicht zugeschmolzen werden. Dies ist in Figur 1 durch eine Glühlampe 7 mit einem elliptischen Reflektor 9 angedeutet; dadurch kann mit der Glühlampe ein Strahlenbündel 11 auf den Zuschmelzbereich 5 fokussiert werden.FIG. 1 shows a melting shipping container 1 made of glass for a perishable biological material 3 filled into it, which can in particular be a medical sample material. The container 1 has a tapered melting area 5, which consists of infrared-absorbing glass. As a result, the container can easily be carried in this melting area 5 focused incandescent light are melted. This is indicated in Figure 1 by an incandescent lamp 7 with an elliptical reflector 9; as a result, a light beam 11 can be focused on the melting region 5 with the incandescent lamp.

Der dargestellte Behälter 1 besteht einstückig ganz aus infrarotabsorbierendem Glas. Dadurch ist die Herstellung leichter möglich als bei Ausführungsformen, bei denen nur in dem Zuschmelzbereich 5 ein infrarot-absorbierendes Material, vorzugsweise aus Glas, vorgesehen ist, das mit den übrigen Teilen des Behälters, die aus normalem Behälterglas bestehen, verbunden, vorzugsweise verschmolzen ist.The container 1 shown consists in one piece entirely of infrared-absorbing glass. This makes production easier than in embodiments in which an infrared-absorbing material, preferably made of glass, is provided only in the melting region 5, which is connected, preferably fused, to the other parts of the container, which consist of normal container glass.

Als infrarot-absorbierendes Glas ist besonders die Glassorte Nr. 8516 der Firma SCHOTT GLASWERKE, Mainz, geeignet. Vorteilhaft ist es ferner, wenn der Behälter zumindest in dem Zuschmelzbereich aus einem Glas besteht, das eine niedrige Verarbeitungstemperatur hat, z.B. etwa 950-1000°C; dies ist bei dem genannten Glas Nr. 8516 der Firma SCHOTT GLASWERKE der Fall.Glass type No. 8516 from SCHOTT GLASWERKE, Mainz, is particularly suitable as infrared-absorbing glass. It is also advantageous if the container, at least in the melting area, consists of a glass that has a low processing temperature, e.g. about 950-1000 ° C; this is the case with the aforementioned glass No. 8516 from SCHOTT GLASWERKE.

Besonders vorteilhaft ist es, wenn der Behälter als Untersuchungsbehälter zur Verwendung bei einer Untersuchung des biologischen Materials ausgebildet ist. Zu diesem Zweck hat der dargestellte Behälter im Querschnitt eine unrunde Form mit zwei gegenüberliegenden parallelen ebenen Seitenwänden 13 und 15. Dadurch kann der Behälter z.B. als Küvette für optische Untersuchungen verwendet werden, so daß ein Umfüllen nicht erforderlich ist.It is particularly advantageous if the container is designed as an examination container for use in examining the biological material. For this purpose, the container shown has a non-circular shape in cross-section with two opposite, parallel, flat side walls 13 and 15. As a result, the container can e.g. can be used as a cuvette for optical examinations, so that refilling is not necessary.

Zweckmäßigerweise weist der Behälter in genügendem Abstand von dem Zuschmelzbereich 5 wenigstens eine Sollbruchzone 17 auf, die in verschiedener Weise hergestellt sein kann, z.B. durch Einritzungen, Anätzungen oder in besonders vorteilhafter Weise in Form einer Vorspannzone, die durch eine örtliche Wärmebehandlung des Behälters hergestellt werden kann. Zweckmäßigerweise hat der Behälter 1 wenigstens eine Markierung 19, die auf den Ort einer Sollbruchzone hinweist.The container expediently has at least one predetermined breaking zone 17 at a sufficient distance from the melting region 5, which can be produced in various ways, for example by scratching, etching or, in a particularly advantageous manner, in the form of a prestressing zone which can be produced by local heat treatment of the container . The container 1 expediently has at least one marking 19 which indicates the location of a predetermined breaking zone.

Um das Zuschmelzen zu erleichtern und den Ort des Zuschmelzens zu kennzeichnen, ist zweckmäßigerweise die Zuschmelzzone 5, wie dargestellt, verjüngt ausgebildet.In order to facilitate the melting and to mark the location of the melting, the melting zone 5 is expediently tapered, as shown.

Figur 2 zeigt den Behälter 12 nach dem Zuschmelzen. Die dabei hergestellte Abschmelzspitze 21 bildet einen hermetischen Verschluß.Figure 2 shows the container 12 after melting. The melting tip 21 produced thereby forms a hermetic seal.

Figur 3 zeigt eine Ausführungsform, bei der ein Behälter 301, der im übrigen wie der in den Figuren 1 und 2 dargestellte Behälter 1 gestaltet sein kann, mit einer zusammenhängenden Kunststoff- schicht 23 ummantelt ist. Diese Kunststoffschicht verhindert bei einem Bruch des Behälters 301 ein Austreten von biologischem Material. Außerdem kann eine Kunststoffschicht verwendet werden, die sich leicht beschriften läßt.FIG. 3 shows an embodiment in which a container 301, which otherwise can be designed like the container 1 shown in FIGS. 1 and 2, is encased with a coherent plastic layer 23. If the container 301 breaks, this plastic layer prevents the escape of biological material. In addition, a plastic layer that can be easily labeled can be used.

Claims (12)

1. A glass dispatch-container (1) which can be sealed by melting, for perishable biological material, in particular medical sample material, and having a region (5) sealable by melting, characterised in that the sealable region presents an infrared-absorbing material.
2. A container according to Claim 1, characterised in that the infrared-absorbing material is a material absorbing preferably in the near infrared.
3. A container according to Claim 1 or 2, characterised in that the infrared-absorbing material is an infrared-absorbing glass.
4. A container according to Claim 3, characterised in that it consists entirely of infrared-absorbing glass.
5. A container according to any one of the preceding claims, characterised in that the container, at least in the sealable region, consists of a glass which has a low manufacturing temperature.
6. A container according to Claim 5, characterised in that the glass has a manufacturing temperature of about 950 to 1000°C.
7. A container according to any one of Claims 3 to 6, characterised in that the infrared-absorbing glass is the glass No. 8516 of SCHOTT GLASWERKE, Mainz.
8. A container according to any one of the preceding claims, characterised in that it is designed as an examination container for use when the biological material is being examined.
9. A container according to any one of the preceding claims, characterised in that it has at least one rated breaking zone (17).
10. A container according to Claim 9, characterised in that the rated breaking zone (17) is a pre-stressed zone.
11. A container according to Claim 9 or 10, characterised in that it has at least one marking (19) pointing to a rated braking zone (17).
12. A container according to any one of the preceding claims, characterised in that it is sheathed with an inherently cohesive layer (23) of plastics material.
EP89104150A 1988-03-31 1989-03-09 Sealable glass shipping container for biological material Expired - Lifetime EP0335145B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT89104150T ATE72396T1 (en) 1988-03-31 1989-03-09 CLOSED GLASS SHIPPING CONTAINER FOR BIOLOGICAL MATERIAL.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3810939 1988-03-31
DE3810939A DE3810939A1 (en) 1988-03-31 1988-03-31 MELTED GLASS SHIPPING CONTAINER FOR BIOLOGICAL MATERIAL

Publications (3)

Publication Number Publication Date
EP0335145A2 EP0335145A2 (en) 1989-10-04
EP0335145A3 EP0335145A3 (en) 1989-12-27
EP0335145B1 true EP0335145B1 (en) 1992-02-05

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EP89104150A Expired - Lifetime EP0335145B1 (en) 1988-03-31 1989-03-09 Sealable glass shipping container for biological material

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US (1) US5105957A (en)
EP (1) EP0335145B1 (en)
JP (1) JPH0296629A (en)
AT (1) ATE72396T1 (en)
DE (2) DE3810939A1 (en)
ES (1) ES2030226T3 (en)
GR (1) GR3003739T3 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413644B2 (en) * 1997-03-03 2002-07-02 R.J. Reynolds Tobacco Company Thin film structures for and method of sealing to glass
JP3902333B2 (en) * 1998-06-24 2007-04-04 日本電気硝子株式会社 Infrared absorbing glass for reed switch
WO2001016042A1 (en) * 1998-06-24 2001-03-08 Nippon Electric Glass Co., Ltd. Infrared absorbing glass for reed switch
DE19940706A1 (en) * 1999-08-27 2001-03-08 Schott Glas Lockable glass container with an overmolded plastic coating and method for its production
US20030021969A1 (en) * 2001-06-29 2003-01-30 Aloisi Robert J. Reflective heat-shrinking film
US20030015274A1 (en) * 2001-06-29 2003-01-23 Mallman A. James Reflective hood for heat-shrinking film onto an open-topped container and method of using same
US7089718B2 (en) * 2002-06-10 2006-08-15 Green-Line Products, Inc. Apparatus for heat-shrinking film onto an open-topped container and method of using same
US20040068968A1 (en) * 2002-06-10 2004-04-15 Biba Scott I. Modular rotational assembly
US20040035088A1 (en) * 2002-06-10 2004-02-26 Loeffler Herbert H. Container positioning device
US7637500B2 (en) * 2006-03-28 2009-12-29 Hewlett-Packard Development Company, L.P. Advancing a media sheet along a media path
US7943189B2 (en) * 2007-10-26 2011-05-17 Lee Ferrell Food preservation packaging system
CN107464597A (en) * 2017-08-30 2017-12-12 中广核研究院有限公司 Hot industry cobalt source anti-leak encapsulating structure and packaging technology

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE473289A (en) *
US2517604A (en) * 1948-08-04 1950-08-08 Owens Illinois Glass Co Ampoule with breakable neck
DE845564C (en) * 1949-12-02 1952-08-04 Mix & Genest Ag Method and device for heating thermoplastic materials by means of heat jets for the purpose of hot working
DE1105560B (en) * 1959-09-01 1961-04-27 Heinz Kock Dr Ampoule-shaped glass container for holding decomposable or non-permanent liquids
NL6510316A (en) * 1965-08-06 1967-02-07
US3535070A (en) * 1966-02-03 1970-10-20 Owens Illinois Inc Method of inducing stress in glass containers and container made with a stressed zone
FR1549511A (en) * 1967-10-31 1968-12-13
DE1796232B1 (en) * 1968-09-25 1971-08-05 Jenaer Glaswerk Schott & Gen HEAT-ABSORBING AND ELECTRICALLY HIGH-ELECTRICALLY INSULATING ZGLAESER WITH THERMAL EXPANSION COEFFICIENTS BETWEEN 91.5 AND 94.9 X 10 UP TO 7 PER DEGREE C (20 TO 300 DEGREES C) TO BE MELTED WITH THE HELP OF HEATING RAYS
GB1497190A (en) * 1975-01-30 1978-01-05 Jenaer Glaswerk Schott & Gen Glass compositions
US3949335A (en) * 1975-04-21 1976-04-06 Corning Glass Works Reed switch construction
US3961970A (en) * 1975-04-21 1976-06-08 Corning Glass Works Reed switch construction
JPS52147617A (en) * 1976-06-03 1977-12-08 Toyo Glass Co Ltd Colored frit
SE414486B (en) * 1977-05-13 1980-08-04 Plm Ab CONTAINER FOR DELICIOUS GOODS
US4156626A (en) * 1977-07-18 1979-05-29 Souder James J Method and apparatus for selectively heating discrete areas of surfaces with radiant energy
FR2446263A1 (en) * 1979-01-12 1980-08-08 Corning Glass Works SEALING GLASS HAVING A HIGH ABSORPTION COEFFICIENT FOR INFRARED RAYS
DE2930912C2 (en) * 1979-07-30 1981-10-15 Jenaer Glaswerk Schott & Gen., 6500 Mainz Crack-resistant, heat-absorbing fusion glasses in the system SiO ↓ 2 ↓ -Al ↓ 2 ↓ O ↓ 3 ↓ -Na ↓ 2 ↓ O-PbO-Fe ↓ 3 ↓ O ↓ 4 ↓ with low processing temperatures for the hermetic encapsulation of electrical components
DE8601774U1 (en) * 1986-01-24 1986-06-12 Bünder Glas GmbH, 4980 Bünde Glass ampoule
DE3615287A1 (en) * 1986-05-06 1987-11-12 Schott Ruhrglas GLASS CASE, IN PARTICULAR AMPOULE, AND METHOD FOR TREATING THIS GLASS CASE
US4826025A (en) * 1986-11-21 1989-05-02 Toppan Printing Co., Ltd. & Mect Corp. Ampoule package

Also Published As

Publication number Publication date
ATE72396T1 (en) 1992-02-15
DE58900811D1 (en) 1992-03-19
EP0335145A3 (en) 1989-12-27
ES2030226T3 (en) 1992-10-16
EP0335145A2 (en) 1989-10-04
GR3003739T3 (en) 1993-03-16
JPH0296629A (en) 1990-04-09
US5105957A (en) 1992-04-21
DE3810939A1 (en) 1989-10-19

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