EP0191168B1 - Vorrichtung zur Aufbewahrung und zur Erinnerung eines Patienten an eine erforderliche Einnahme von Arzneimitteln - Google Patents

Vorrichtung zur Aufbewahrung und zur Erinnerung eines Patienten an eine erforderliche Einnahme von Arzneimitteln Download PDF

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Publication number
EP0191168B1
EP0191168B1 EP19850115447 EP85115447A EP0191168B1 EP 0191168 B1 EP0191168 B1 EP 0191168B1 EP 19850115447 EP19850115447 EP 19850115447 EP 85115447 A EP85115447 A EP 85115447A EP 0191168 B1 EP0191168 B1 EP 0191168B1
Authority
EP
European Patent Office
Prior art keywords
sensors
disposed
supporting plate
film
medication container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19850115447
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0191168A2 (de
EP0191168A3 (en
Inventor
Udo Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AT85115447T priority Critical patent/ATE50912T1/de
Publication of EP0191168A2 publication Critical patent/EP0191168A2/de
Publication of EP0191168A3 publication Critical patent/EP0191168A3/de
Application granted granted Critical
Publication of EP0191168B1 publication Critical patent/EP0191168B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • G—PHYSICS
    • G04—HOROLOGY
    • G04B—MECHANICALLY-DRIVEN CLOCKS OR WATCHES; MECHANICAL PARTS OF CLOCKS OR WATCHES IN GENERAL; TIME PIECES USING THE POSITION OF THE SUN, MOON OR STARS
    • G04B37/00—Cases
    • G04B37/12—Cases for special purposes, e.g. watch combined with ring, watch combined with button
    • G04B37/127—Cases for special purposes, e.g. watch combined with ring, watch combined with button used as containers or cartridges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
    • A61J7/0436—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system resulting from removing a drug from, or opening, a container

Definitions

  • the invention relates to a device for storing and for reminding a patient of the need to take medication with the features of the preamble of claim 1.
  • Such a device is known from DE-A-3335301 or EP-A-129785 and i.w. a signal generator attached to a blister pack, which is intended to remind the patient of the correct and exact intake of the coated tablets or the like stored in the blister pack.
  • the clock of the known device is equipped with a setting input which is actuated whenever a coated tablet is pressed through the push-through film of the blister. This is done in that a conductor track is placed over the area of the film which can be pushed through and is severed when the area is torn, as a result of which an impulse is given to the watch. Further details relating to the switching of the clock and the formation of the conductor tracks can be found in said publication, all details can also advantageously be used in the present invention.
  • the known device is disadvantageous in that the blister pack itself has to be provided with vapor-deposited or printed lines, which makes the manufacture of the drug itself slightly more expensive, furthermore requires a very costly conversion of the packaging machines used in the pharmaceutical industry and, in particular, represents an unnecessary additional cost burden as not all blister packs with a printed conductor track can actually be used with a clock controlled thereby.
  • the invention has for its object to provide a device for storage to remind a patient of the need to take medication in such a way that the intake signal transmitter (clock) can be controlled as a function of the actual removal of the coated tablets from the blister pack without the Blister pack itself needs to be changed in some way.
  • This object is achieved by the characterizing features of claim 1.
  • the frame is used to hold the sensors and the clock on the medication pack.
  • the holding frame is designed so that the dragees or tablets can be removed from the dragee container, even if it is fastened in the frame.
  • the frame is partially open at least on its underside, so that the coated tablets can be expressed.
  • the upper side can either also be made open, whereby the coated tablets are expressed by direct finger pressure on the depressions of the first film, or a cover plate of some type with flexible elements is provided, via which pressure is indirectly exerted on the depressions to express the coated tablets can.
  • the invention makes it possible to provide ready-made drage containers in a completely unchanged manner with a clock which is precisely controlled by the removal of cans from the package. Furthermore, it is left open in claim 1 whether the sensors are to be arranged directly on the frame or are attached to a separate sensor carrier which can be inserted into the frame or attached to it.
  • the support plate then likewise represents a sensor carrier. If the support plate is designed as a separate plate that can be detached from the frame, a uniform frame can be used for different blister packs, the support plate then represents, as it were, an adaptation adapter for different blister packs. In this case, problem-free electrical contact between frame, watch and in particular support plate To ensure, the support plate is provided with system contacts that are connected to lines leading to the sensors and act on correspondingly arranged counter contacts of the frame or the clock in the operating position.
  • the frame advantageously consists of a lower part and an upper part, the upper part being held in the position of use by a snap-snap connection on the lower part and covering the medicament container on the edge.
  • the hinge can be designed, for example, as a plastic film hinge.
  • Claims 12-15 deal with different types of sensors attached to or interacting with the frame.
  • the sensors are mechanical small switches according to claim 13, which are arranged on or inside the pressure plate.
  • the sensors are severable conductor track sections which are arranged on a separate film which can be partially torn under the medicament container and which can be torn.
  • the generic document P 33 35 308.1 all of the conductor tracks, circuit measures and the like. Similar features can also be used with advantage in the present invention.
  • Claims 17-19 deal with measures as to how the separate film with the necessary exact spatial allocation can be arranged in the frame or on the blister pack.
  • the sensors are electrical pushbutton switches which, via. H. are arranged on the side of the blister pack provided with recesses and apply ejection elements to the recesses of the blister in the ejection direction.
  • the pushbuttons have a double function in that, on the one hand, they cause the dragees to be pushed through the separable second film as pressure elements and, on the other hand, they serve as electrical switching means. It is possible to arrange the sensors in the form of the pushbutton switches in or on a separate holding plate and thus match them to the blister size and drage arrangement in the blister; the pushbutton switches can also be provided in a holding plate formed in one piece with the frame.
  • the sensors are to be arranged on or in the region of the underside of the support plate or are carried by a frame base. It may be advantageous, for optical or functional reasons, to close the frame on its underside and thus i. w. to give a closed, can-like shape.
  • the lid of the can-like container is opened, whereby the welded-in coated tablets are exposed for being pushed through the film.
  • the underside of the tablet blister lies on a support plate, under which the sensors are arranged so that they respond when a dragee passes through the associated opening of the support plate or whatever type of support device (a plurality of support projections is also conceivable, which protrude upwards from the frame base against the underside of the blister and carry it).
  • the sensors are expediently designed as pressure sensors and can be embedded in a flexible and compressible layer. If pushbutton switches are used as sensors (cf. claim 20), it may be expedient to cover them with a flexible layer in order to prevent the coated tablets from being injured when they are pushed through by angular projections of the pushbutton arrangement. It is important that only the pushbutton switch or sensor assigned to the respective dragee may respond if the corresponding dragee is pressed through.
  • pressure-transmitting projections are formed on the flexible layer, which protrude in the direction of the respective dragee and are either shifted in the direction of the sensor or tilted sideways when the dragee is pushed through, as a result of which the sensor also responds.
  • the part carrying the sensors below the coated tablets namely the sensor carrier
  • at least one coated tablet ejection opening in order to ensure that the coated tablet is not inside, ie. H. between the blister / support plate and sensor carrier and possibly damaged.
  • Sensor for example a pushbutton switch
  • both lines assigned to it are acted upon.
  • nxm matrix arrangement it is possible to make do with only n + m lines, which considerably simplifies the line routing (e.g. with thirty sensors arranged in six rows and five columns - eleven lines leading to the clock are sufficient to do so localize the response of each individual sensor).
  • This is particularly advantageous if dragees of different duration of action are provided in a pack and the time intervals of the clock are to be set automatically depending on the duration of action of a dragee removed.
  • the setting device for the clock can also be advantageous to design the setting device for the clock as further pushbutton switches, which are likewise arranged on a plate of the frame in a manner similar to the pushbutton switches described above.
  • the signal transmitter the clock
  • the signal transmitter should also be provided with a memory for storing the times when the medications were taken from the pack, the times of removal being shown on a display on the clock or on a display separate output unit that can be connected to an output of the clock can be represented.
  • the watch advantageously has display means which indicate a missed intake of a dragee, which can be carried out by intermittent flashing or intermittent acoustic signals (reminders of the intake, for example, every 10 minutes) in order to protect the voltage source provided in the watch.
  • the device 1 for storing and reminding a patient of the need to take medication consists i. w. from a medicament container 2 in the form of a blistered dragee container, in which the dragees 3 are welded between a first film 5 provided with recesses 4 forming recesses and a second film 6 which can be pushed through. Furthermore, a signal generator 7 which can be activated according to settable time intervals is provided, which is designed as an electrical clock with signal generator 8 and an optical signal display 9 and a display 10, and has an electrically activatable start input 11 which receives an electrical one when a dragee 3 is first removed from the medicament container 2 Start pulse is supplied, for which 3 responsive sensors are provided for removing the dragees.
  • the signal generator 7 is arranged on a holding frame 13 which at least partially encompasses the edge region 12 of the medicament container 2 and which, due to its at least partially open configuration at least below, enables the dragees 3 to be squeezed out of the coated container inserted in the holding frame, part of which from the signal generator to the sensors carries leading lines 14 and on which the sensors 15 are arranged either directly or via a sensor carrier 16 which can be fastened to the holding frame 13.
  • the signal transmitter 7 is detachably fastened to the holding frame 13 by means of a snap-snap connection 17, input / output contacts of the signal transmitter 7 act on counter contacts arranged on the holding frame, which are connected to the lines 14 provided in the holding frame 13.
  • the holding frame 13 is provided on its underside 18 with a projecting edge 19 which partially covers the underside 20 of the medicament container 2.
  • a support plate 22 provided with push-through recesses 21 is arranged between the projecting edge 19 and the underside 20, which in the exemplary embodiment shown in FIG. 2 simultaneously forms the sensor carrier 16. It is also within the scope of the invention to form the lower frame part 13 "in one piece with the support plate.
  • the sensors 15 are fastened to the support plate in the area of the push-through recesses 21, the support plate 22, which has lines 14 leading to the sensors 15, is provided with the lines 14, electrically connected contact contacts 23, which in the operating position act on correspondingly arranged counter contacts 24 of the holding frame 13 .
  • the support plate 22 is provided on opposite longitudinal sides 25 with inwardly open U-shaped grooves 26 for receiving the side edges of the medicament container 2.
  • the support plate 22 has cutting edges 27 surrounding the push-through recesses 21.
  • the holding frame 13 consists of an upper frame part 13 'and a lower frame part 13 ", the upper part 13' being held in the position of use by a further snap-locking connection 28 on the lower part 13" and covering the medicament container 2 on the edge.
  • the sensors 15, which are fastened in the support plate 22, have a sensor 30 which protrudes into the push-through path of the dragées 3 and which can be designed as a push pin, swivel tongue or the like and with an electrical contact cooperates. Furthermore, it is possible to design the sensor 30 as a fixed contact arranged in the push-through recess, which is acted upon by a foil section of the second metallic foil 6 which tears or tears when pressed through and forms a counter-contact and protrudes into the push-through recess.
  • the sensors 15 are designed as severable conductor track sections 31, which are arranged on a separate film 32 that can be partially torn under the medication container 2, which can be achieved by vapor deposition, printing, gluing and the like. Like. Can happen.
  • the separate film 32 is held between the medicament container 2 and the support plate 22 with a clamp fit, it is also possible to provide the separate film 32 with at least one holding adjustment recess 33 which interacts with a holding and adjustment projection 34 of the frame 13 or the support plate 22.
  • the sensors are designed as electrical pushbutton switches 40, which are switched over, i. H. are arranged on the side of the blister pack provided with the recesses forming the receiving pockets and act on the receiving pockets 4 of the medicament container 2 in the ejection direction (arrow 42) with ejection elements (plunger 41).
  • the push button switches 40 are arranged in a separate holding plate 43 in the illustrated embodiment. However, it is also possible to fasten the pushbutton switches on a plate-like carrier which is formed in one piece with the upper frame part 13 '.
  • the sensors namely the pushbutton switches 40
  • the lines 14 are arranged in a matrix over a corresponding arrangement of coated tablets.
  • input elements are formed on the holding plate 43 with an adjusting device (for example a setting device) of the signal transmitter 7 as further push buttons 46, 47, the function of which can be switched off by means of a switching device (not shown).
  • an adjusting device for example a setting device
  • the function of which can be switched off by means of a switching device (not shown).
  • the sensors 50 are arranged in the region of the underside 51 of the support plate 22.
  • the sensors are designed as pushbutton switches, but are not actuated directly by the operator, but rather by the depressed dragées 3. This is illustrated by the directional arrows 52, 53 in FIG. 9.
  • 54 coated tablet discharge openings 55 are provided in the sensor carrier.
  • the sensors are designed as pressure sensors 57 embedded in a flexible and compressible layer 56, the layer on the side 58 facing the blister of an i. w. closed frame base 59 is arranged.
  • Pressure transmission projections 60 are arranged on the flexible layer 56, which are pushed or tilted when the dragees are pushed through, either in the direction of arrow 61 or in the pushing direction 62, and thus trigger a signal which is sent from sensor 57 to a matrix-like network of row lines 63 and Column lines 64 are given, which are embedded in the flexible and compressible layer 56.
  • the drage ejection opening is not shown and is located on a side surface of the frame.
  • the signal generator 7 (the watch) has a memory 48 for the interrogable storage of the withdrawal times of the medicaments from the package, the removal times being able to be shown on the display 10 of the watch or a separate output unit which can be connected to an output of the watch, which is not shown further.
  • switching means are provided in the clock which, if the dragee is not taken or removed from the pack in a timely manner, actuate a separate display device or display a specific symbol on the display 10 in order to indicate the missed intake.

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Measurement Of Predetermined Time Intervals (AREA)
  • External Artificial Organs (AREA)
  • Warehouses Or Storage Devices (AREA)
  • Packages (AREA)
EP19850115447 1985-02-09 1985-12-05 Vorrichtung zur Aufbewahrung und zur Erinnerung eines Patienten an eine erforderliche Einnahme von Arzneimitteln Expired - Lifetime EP0191168B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT85115447T ATE50912T1 (de) 1985-02-09 1985-12-05 Vorrichtung zur aufbewahrung und zur erinnerung eines patienten an eine erforderliche einnahme von arzneimitteln.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE8503564U DE8503564U1 (de) 1985-02-09 1985-02-09 Vorrichtung zur Aufbewahrung und zeitlich veranlaßten Einnahme von Arzneimitteln
DE8503564U 1985-02-09

Publications (3)

Publication Number Publication Date
EP0191168A2 EP0191168A2 (de) 1986-08-20
EP0191168A3 EP0191168A3 (en) 1987-10-28
EP0191168B1 true EP0191168B1 (de) 1990-03-14

Family

ID=6777235

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19850115447 Expired - Lifetime EP0191168B1 (de) 1985-02-09 1985-12-05 Vorrichtung zur Aufbewahrung und zur Erinnerung eines Patienten an eine erforderliche Einnahme von Arzneimitteln

Country Status (5)

Country Link
US (1) US4660991A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0191168B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS61185267A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE50912T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE8503564U1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836100A1 (de) * 1998-08-10 2000-02-24 Kasper & Richter Gmbh Vorrichtung zur Aufbewahrung eines Arzneimittelbehälters
DE10118313C1 (de) * 2001-04-11 2002-12-12 Dieter Hafner Sensorvorrichtung an einem Arzneimittelbehältnis, insbesondere an einer Blisterpackung für Arzneimittel in Tabletten- oder Drageeform
DE10217929A1 (de) * 2002-04-22 2003-11-06 Sixp Ag Vorrichtung zur Ausgabe von Tabletten
DE10213547C1 (de) * 2002-02-14 2003-11-27 Udo Simon Blisterpackungsanordnung

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ATE50912T1 (de) 1990-03-15
JPH0236264B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-08-16
EP0191168A2 (de) 1986-08-20
JPS61185267A (ja) 1986-08-18
US4660991A (en) 1987-04-28
EP0191168A3 (en) 1987-10-28
DE8503564U1 (de) 1985-05-15
DE3576456D1 (de) 1990-04-19

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