EG14639A - Process for preparing of novel spiro oxazolidindiones useful as aldose reductace inhibitors and as therapeutic agent - Google Patents
Process for preparing of novel spiro oxazolidindiones useful as aldose reductace inhibitors and as therapeutic agentInfo
- Publication number
- EG14639A EG14639A EG79509A EG50979A EG14639A EG 14639 A EG14639 A EG 14639A EG 79509 A EG79509 A EG 79509A EG 50979 A EG50979 A EG 50979A EG 14639 A EG14639 A EG 14639A
- Authority
- EG
- Egypt
- Prior art keywords
- reductace
- oxazolidindiones
- aldose
- inhibitors
- preparing
- Prior art date
Links
- 150000001323 aldoses Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 spiro oxazolidindiones Chemical class 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Photosensitive Polymer And Photoresist Processing (AREA)
- Moulding By Coating Moulds (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/935,199 US4200642A (en) | 1978-08-21 | 1978-08-21 | Spiro-oxazolidindiones |
Publications (1)
Publication Number | Publication Date |
---|---|
EG14639A true EG14639A (en) | 1985-03-31 |
Family
ID=25466700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EG79509A EG14639A (en) | 1978-08-21 | 1979-08-20 | Process for preparing of novel spiro oxazolidindiones useful as aldose reductace inhibitors and as therapeutic agent |
Country Status (34)
Country | Link |
---|---|
US (1) | US4200642A (de) |
JP (4) | JPS6011914B2 (de) |
AR (1) | AR225614A1 (de) |
AT (1) | AT366689B (de) |
AU (1) | AU535170B2 (de) |
BE (1) | BE878311A (de) |
CA (1) | CA1121361A (de) |
CH (1) | CH639974A5 (de) |
CS (1) | CS208129B2 (de) |
DD (1) | DD146602A5 (de) |
DE (2) | DE2933441C2 (de) |
DK (1) | DK258479A (de) |
EG (1) | EG14639A (de) |
ES (1) | ES483511A1 (de) |
FI (1) | FI65255C (de) |
FR (3) | FR2442851A1 (de) |
GB (2) | GB2028318B (de) |
GR (1) | GR71913B (de) |
HU (1) | HU179746B (de) |
IE (1) | IE48932B1 (de) |
IL (1) | IL58076A (de) |
IN (1) | IN152416B (de) |
IT (1) | IT1123536B (de) |
LU (1) | LU81613A1 (de) |
NL (1) | NL7906318A (de) |
NO (1) | NO792699L (de) |
NZ (1) | NZ191350A (de) |
PH (1) | PH18091A (de) |
PL (1) | PL130686B1 (de) |
PT (1) | PT70086A (de) |
SE (1) | SE447116B (de) |
SU (1) | SU942597A3 (de) |
YU (1) | YU41488B (de) |
ZA (1) | ZA794379B (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4329459A (en) * | 1980-05-05 | 1982-05-11 | The Upjohn Company | Tetrahydrobenzopyran derivatives |
SG56656G (en) * | 1980-07-28 | 1987-03-27 | Pfizer | Hypoglycemic 5-substituted oxazolidine-2, 4-diones |
US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
ES8400116A1 (es) * | 1981-10-13 | 1983-10-16 | Pfizer | "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona". |
US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
US4464385A (en) * | 1982-04-15 | 1984-08-07 | Alcon Laboratories, Inc. | Treatment of diabetic complications with hydantoins |
US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
ZA832679B (en) * | 1982-05-07 | 1983-12-28 | Ici Plc | Indoline derivatives |
US4430337A (en) | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
US4556670A (en) * | 1982-12-06 | 1985-12-03 | Pfizer Inc. | Spiro-3-hetero-azolones for treatment of diabetic complications |
US4464380A (en) * | 1983-05-25 | 1984-08-07 | Pfizer Inc. | Imidazolidinedione derivatives |
US4533667A (en) * | 1983-05-25 | 1985-08-06 | Pfizer Inc. | Imidazolidinedione derivatives |
DK277484A (da) * | 1983-06-23 | 1984-12-24 | Hoffmann La Roche | Thiazolidinderivater |
JPS61200991A (ja) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤 |
DE3522791C1 (en) * | 1985-06-26 | 1987-01-02 | Ferroplast Gmbh | Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling |
WO1987004344A1 (en) * | 1986-01-17 | 1987-07-30 | Pfizer Inc. | Hydroxyacetic acid derivatives for the treatment of diabetic complications |
US5039672A (en) * | 1990-04-05 | 1991-08-13 | Pfizer Inc. | Heterocyclic compounds as aldose reductase inhibitors |
US5068332A (en) * | 1990-10-12 | 1991-11-26 | American Home Products Corporation | Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors |
US5102886A (en) * | 1990-10-12 | 1992-04-07 | American Home Products Corporation | 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors |
FR2707981B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
CA2377246A1 (en) | 1999-06-18 | 2000-12-28 | Ranjit C. Desai | Arylthiazolidinedione and aryloxazolidinedione derivatives |
EP1194146B1 (de) | 1999-06-18 | 2006-07-19 | Merck & Co., Inc. | Arylthiazolidinedione und aryloxa zolidinedion-derivate |
ITPI20060083A1 (it) * | 2006-07-11 | 2008-01-12 | Univ Pisa | Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico |
USD775790S1 (en) * | 2015-11-18 | 2017-01-10 | Ginger Damon | Motorcycle jacket |
RU2020123382A (ru) | 2017-12-21 | 2022-01-21 | Эссити Хайджин Энд Хелт Актиеболаг | Впитывающее изделие и способ изготовления впитывающего изделия |
WO2019125232A1 (en) | 2017-12-21 | 2019-06-27 | Essity Hygiene And Health Aktiebolag | Absorbent article with channel sealings and method for manufacturing the absorbent article |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1204232B (de) * | 1959-07-16 | 1965-11-04 | Ncr Co | Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)] |
US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
-
1978
- 1978-08-21 US US05/935,199 patent/US4200642A/en not_active Expired - Lifetime
-
1979
- 1979-06-20 DK DK258479A patent/DK258479A/da not_active Application Discontinuation
- 1979-06-21 IN IN451/DEL/79A patent/IN152416B/en unknown
- 1979-07-27 GB GB7926348A patent/GB2028318B/en not_active Expired
- 1979-08-16 YU YU1999/79A patent/YU41488B/xx unknown
- 1979-08-16 CH CH752879A patent/CH639974A5/fr not_active IP Right Cessation
- 1979-08-17 CA CA000333955A patent/CA1121361A/en not_active Expired
- 1979-08-17 DE DE2933441A patent/DE2933441C2/de not_active Expired
- 1979-08-17 HU HU79PI685A patent/HU179746B/hu unknown
- 1979-08-17 DE DE2953954A patent/DE2953954C2/de not_active Expired
- 1979-08-17 FI FI792567A patent/FI65255C/fi not_active IP Right Cessation
- 1979-08-18 JP JP54105459A patent/JPS6011914B2/ja not_active Expired
- 1979-08-20 SE SE7906949A patent/SE447116B/sv not_active IP Right Cessation
- 1979-08-20 AT AT0560579A patent/AT366689B/de not_active IP Right Cessation
- 1979-08-20 LU LU81613A patent/LU81613A1/fr unknown
- 1979-08-20 IE IE1592/79A patent/IE48932B1/en not_active IP Right Cessation
- 1979-08-20 PT PT70086A patent/PT70086A/pt unknown
- 1979-08-20 AU AU50092/79A patent/AU535170B2/en not_active Ceased
- 1979-08-20 IL IL58076A patent/IL58076A/xx unknown
- 1979-08-20 GR GR59870A patent/GR71913B/el unknown
- 1979-08-20 FR FR7920969A patent/FR2442851A1/fr active Granted
- 1979-08-20 BE BE0/196785A patent/BE878311A/fr not_active IP Right Cessation
- 1979-08-20 SU SU792803649A patent/SU942597A3/ru active
- 1979-08-20 ES ES483511A patent/ES483511A1/es not_active Expired
- 1979-08-20 ZA ZA00794379A patent/ZA794379B/xx unknown
- 1979-08-20 EG EG79509A patent/EG14639A/xx active
- 1979-08-20 NZ NZ191350A patent/NZ191350A/en unknown
- 1979-08-20 NO NO792699A patent/NO792699L/no unknown
- 1979-08-20 IT IT25182/79A patent/IT1123536B/it active
- 1979-08-21 NL NL7906318A patent/NL7906318A/nl active Search and Examination
- 1979-08-21 CS CS795699A patent/CS208129B2/cs unknown
- 1979-08-21 DD DD79215099A patent/DD146602A5/de unknown
- 1979-08-21 AR AR277784A patent/AR225614A1/es active
- 1979-08-21 PH PH22931A patent/PH18091A/en unknown
- 1979-08-21 PL PL1979217881A patent/PL130686B1/pl unknown
- 1979-08-27 GB GB8001161A patent/GB2033904B/en not_active Expired
- 1979-11-16 JP JP54148747A patent/JPS5946517B2/ja not_active Expired
- 1979-11-16 JP JP54148749A patent/JPS5943954B2/ja not_active Expired
- 1979-11-16 JP JP54148748A patent/JPS6011915B2/ja not_active Expired
-
1980
- 1980-02-07 FR FR8002698A patent/FR2440950A1/fr active Granted
- 1980-02-07 FR FR8002697A patent/FR2440949A1/fr active Granted
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