EG11013A - Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines - Google Patents

Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines

Info

Publication number
EG11013A
EG11013A EG431/72A EG43172A EG11013A EG 11013 A EG11013 A EG 11013A EG 431/72 A EG431/72 A EG 431/72A EG 43172 A EG43172 A EG 43172A EG 11013 A EG11013 A EG 11013A
Authority
EG
Egypt
Prior art keywords
novel
pyrimidinones
preparation
hydroxy pyrimidines
pyrimidines
Prior art date
Application number
EG431/72A
Other languages
English (en)
Inventor
C Lipinski
J Stam
G George
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG11013A publication Critical patent/EG11013A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EG431/72A 1971-10-29 1972-10-19 Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines EG11013A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
EG11013A true EG11013A (en) 1976-11-30

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
EG431/72A EG11013A (en) 1971-10-29 1972-10-19 Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines

Country Status (25)

Country Link
JP (2) JPS5337870B2 (pl)
AR (2) AR198798A1 (pl)
AT (2) AT321308B (pl)
AU (1) AU467600B2 (pl)
BE (1) BE790125A (pl)
CA (1) CA980778A (pl)
CH (2) CH555832A (pl)
DE (3) DE2248741C3 (pl)
DK (1) DK131465B (pl)
EG (1) EG11013A (pl)
ES (2) ES407730A1 (pl)
FI (1) FI55503C (pl)
FR (1) FR2157865B1 (pl)
GB (2) GB1377720A (pl)
IE (1) IE37043B1 (pl)
IL (2) IL40458A (pl)
LU (1) LU66304A1 (pl)
NL (1) NL166470C (pl)
NO (1) NO136574C (pl)
PH (2) PH10129A (pl)
PL (2) PL84634B1 (pl)
SE (2) SE393376B (pl)
SU (2) SU498908A3 (pl)
YU (2) YU35125B (pl)
ZA (1) ZA727362B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (pl) * 1979-04-17 1980-11-01
JPS5752409Y2 (pl) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
NZ565955A (en) 2005-08-22 2011-08-26 Melior Pharmaceuticals I Inc Methods and formulations for modulating lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
NZ758966A (en) 2017-04-10 2024-08-30 Board Of Supervisors Of Louisiana State Univ And Agricultural And Mechanical College Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
FI55503C (fi) 1979-08-10
NO136574C (no) 1977-09-28
JPS5422995B2 (pl) 1979-08-10
NL166470B (nl) 1981-03-16
DE2248741C3 (de) 1975-06-26
DE2264374A1 (de) 1973-05-24
LU66304A1 (pl) 1973-05-03
AU467600B2 (en) 1975-12-04
GB1377720A (en) 1974-12-18
SE397090B (sv) 1977-10-17
AR198798A1 (es) 1974-07-24
JPS4852780A (pl) 1973-07-24
AT321308B (de) 1975-03-25
GB1377308A (en) 1974-12-11
DE2248741A1 (de) 1973-05-03
PL89852B1 (pl) 1976-12-31
IL40458A (en) 1976-05-31
ES407730A1 (es) 1976-01-16
IL48790A (en) 1976-05-31
DK131465C (pl) 1975-12-08
FR2157865A1 (pl) 1973-06-08
PH11594A (en) 1978-03-31
IE37043B1 (en) 1977-04-27
BE790125A (fr) 1973-04-16
AT320656B (de) 1975-02-25
NL166470C (nl) 1981-08-17
SE7505279L (sv) 1975-05-06
JPS5337870B2 (pl) 1978-10-12
FR2157865B1 (pl) 1975-10-31
NO136574B (pl) 1977-06-20
PL84634B1 (pl) 1976-04-30
DK131465B (da) 1975-07-21
YU255172A (en) 1980-03-15
PH10129A (en) 1976-09-02
DE2264374C3 (de) 1981-07-23
SU498908A3 (ru) 1976-01-05
YU35125B (en) 1980-09-25
IL40458A0 (en) 1972-11-28
IL48790A0 (en) 1976-03-31
DE2264657A1 (de) 1974-06-20
SE393376B (sv) 1977-05-09
ES436624A1 (es) 1977-02-01
CA980778A (en) 1975-12-30
YU99179A (en) 1981-08-31
ZA727362B (en) 1973-11-28
DE2264374B2 (de) 1980-08-07
DE2248741B2 (de) 1974-11-14
AU4722872A (en) 1974-04-04
CH549579A (fr) 1974-05-31
IE37043L (en) 1973-04-29
JPS53116386A (en) 1978-10-11
NL7213959A (pl) 1973-05-02
AR196263A1 (es) 1973-12-10
CH555832A (fr) 1974-11-15
YU36295B (en) 1982-06-18
FI55503B (fi) 1979-04-30
DE2264657C2 (de) 1982-09-16
SU505362A3 (ru) 1976-02-28

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