EE9900116A - Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks - Google Patents

Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks

Info

Publication number
EE9900116A
EE9900116A EEP199900116A EE9900116A EE9900116A EE 9900116 A EE9900116 A EE 9900116A EE P199900116 A EEP199900116 A EE P199900116A EE 9900116 A EE9900116 A EE 9900116A EE 9900116 A EE9900116 A EE 9900116A
Authority
EE
Estonia
Prior art keywords
pentaerythritol
intermediates
synthesis
preparation
novel derivatives
Prior art date
Application number
EEP199900116A
Other languages
English (en)
Estonian (et)
Inventor
Hess Ulrich
Windeck Anne-Katrin
Brosig Holger
Original Assignee
Isis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19641667A external-priority patent/DE19641667A1/de
Priority claimed from DE1996152345 external-priority patent/DE19652345A1/de
Priority claimed from DE19726812A external-priority patent/DE19726812A1/de
Application filed by Isis Pharma Gmbh filed Critical Isis Pharma Gmbh
Publication of EE9900116A publication Critical patent/EE9900116A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C06EXPLOSIVES; MATCHES
    • C06BEXPLOSIVES OR THERMIC COMPOSITIONS; MANUFACTURE THEREOF; USE OF SINGLE SUBSTANCES AS EXPLOSIVES
    • C06B25/00Compositions containing a nitrated organic compound
    • CCHEMISTRY; METALLURGY
    • C06EXPLOSIVES; MATCHES
    • C06BEXPLOSIVES OR THERMIC COMPOSITIONS; MANUFACTURE THEREOF; USE OF SINGLE SUBSTANCES AS EXPLOSIVES
    • C06B25/00Compositions containing a nitrated organic compound
    • C06B25/10Compositions containing a nitrated organic compound the compound being nitroglycerine
    • CCHEMISTRY; METALLURGY
    • C06EXPLOSIVES; MATCHES
    • C06BEXPLOSIVES OR THERMIC COMPOSITIONS; MANUFACTURE THEREOF; USE OF SINGLE SUBSTANCES AS EXPLOSIVES
    • C06B25/00Compositions containing a nitrated organic compound
    • C06B25/32Compositions containing a nitrated organic compound the compound being nitrated pentaerythritol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00Esters of nitric or nitrous acid
    • C07C203/02Esters of nitric acid
    • C07C203/04Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
EEP199900116A 1996-10-10 1997-10-10 Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks EE9900116A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19641667A DE19641667A1 (de) 1996-10-10 1996-10-10 Neue Ester der Salpetersäure sowie deren Herstellung und Verwendung
DE1996152345 DE19652345A1 (de) 1996-12-17 1996-12-17 Neue Salpetersäureester, deren Herstellung und Verwendung
DE19726812A DE19726812A1 (de) 1997-06-25 1997-06-25 Neue Derivate des Pentaerythrits, deren Herstellung und Verwendung sowie Intermediate zur Synthese derselben
PCT/DE1997/002328 WO1998015521A1 (de) 1996-10-10 1997-10-10 Neue derivate des pentaerythrits, deren herstellung und verwendung sowie intermediate zur synthese derselben

Publications (1)

Publication Number Publication Date
EE9900116A true EE9900116A (et) 1999-10-15

Family

ID=27216719

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900116A EE9900116A (et) 1996-10-10 1997-10-10 Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks

Country Status (20)

Country Link
US (1) US6180664B1 (no)
EP (1) EP1009730A1 (no)
JP (1) JP2001501627A (no)
CN (1) CN1239944A (no)
AU (1) AU736253B2 (no)
BG (1) BG103303A (no)
BR (1) BR9715045A (no)
CA (1) CA2267129A1 (no)
CZ (1) CZ9901223A3 (no)
EA (1) EA001959B1 (no)
EE (1) EE9900116A (no)
HR (1) HRP970546A2 (no)
IL (1) IL129339A0 (no)
NO (1) NO991622L (no)
NZ (1) NZ335057A (no)
PL (1) PL332594A1 (no)
SK (1) SK43499A3 (no)
TR (1) TR199900791T2 (no)
WO (1) WO1998015521A1 (no)
YU (1) YU17999A (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ501414A (en) 1997-06-11 2001-12-21 Isis Pharma Gmbh Pentaerythritol derivatives, the production and uses thereof and intermediate products for the synthesis of active agents for treating heart/circulation and vascular illnesses
WO1999067430A2 (de) * 1998-06-24 1999-12-29 Alpharma-Isis Gmbh & Co. Kg Analytische substrate und antioxidative mittel
DE19950483A1 (de) * 1999-10-19 2001-05-10 Isis Pharma Gmbh Verfahren zur Herstellung von 3-Nitryloxy-2,2-bis(nitryloxymethyl)-propanal
US20050203142A1 (en) * 2002-10-24 2005-09-15 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
US20040087558A1 (en) * 2002-10-24 2004-05-06 Zeldis Jerome B. Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
US20050065184A1 (en) * 2003-08-29 2005-03-24 Aaipharma Inc. Method of reducing the risk of oxidative stress
CN103848704A (zh) * 2012-11-30 2014-06-11 陕西省汉阴华能新材料研究有限公司 回收油的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1883045A (en) * 1931-11-20 1932-10-18 Du Pont Explosive composition
GB442850A (en) * 1934-05-14 1936-02-17 Bombrini Parodi Delfino Improvements in and relating to the production of explosives
US2389228A (en) * 1943-04-14 1945-11-20 Trojan Powder Co Preparation of tripentaerythritol octanitrate
NL110701C (no) * 1960-03-14
US3419571A (en) * 1966-04-06 1968-12-31 Warner Lambert Pharmaceutical Method for relieving coronary insufficiency
US4394329A (en) * 1979-06-26 1983-07-19 Thiokol Corporation 2-Hydroxymethyl-1,3-propanediol nitrate ester
CS221031B1 (en) * 1981-12-28 1983-04-29 Svatopluk ZEMAN Method of making the nitrates,derivatives of the trimethylmethane

Also Published As

Publication number Publication date
NO991622D0 (no) 1999-04-06
SK43499A3 (en) 2000-02-14
JP2001501627A (ja) 2001-02-06
AU736253B2 (en) 2001-07-26
TR199900791T2 (xx) 1999-07-21
NZ335057A (en) 2000-09-29
NO991622L (no) 1999-06-04
WO1998015521A1 (de) 1998-04-16
CA2267129A1 (en) 1998-04-16
PL332594A1 (en) 1999-09-27
EP1009730A1 (de) 2000-06-21
BR9715045A (pt) 2001-01-16
AU5115598A (en) 1998-05-05
US6180664B1 (en) 2001-01-30
IL129339A0 (en) 2000-02-17
CN1239944A (zh) 1999-12-29
EA001959B1 (ru) 2001-10-22
CZ9901223A3 (cs) 2002-10-16
EA199900363A1 (ru) 1999-12-29
BG103303A (bg) 2000-01-31
YU17999A (sh) 2002-03-18
HRP970546A2 (en) 1998-08-31

Similar Documents

Publication Publication Date Title
NO990756L (no) FremgangsmÕte for fremstilling av mellomprodukter for florfenikol
FI960889A (fi) Naftyyliyhdisteitä, välituotteita, koostumuksia ja menetelmiä
NO980720D0 (no) Pyridazin-3-on-derivater, deres anvendelse og mellomprodukter for deres fremstilling
AU2196897A (en) Novel asymmetric synthesis of r-alpha-propyl-piperonyl amine and its analogs
NO990295D0 (no) FremgangsmÕte for katalytisk fremstilling av N-acylglycinderivater
BR9710648A (pt) S¡ntese de indolilmaleimidas
NO991254L (no) FremgangsmÕter og mellomprodukter for fremstilling av substituerte kromanolderivater
EE9900116A (et) Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks
EE04812B1 (et) 2-fenüülpüraan-4-ooni derivaadid, nende valmistamismeetod ja kasutamine, vaheühendite kasutamine jafarmatseutiline kompositsioon
NO990913D0 (no) Naftylforbindelser, intermediater, sammensetninger og metoder for anvendelse
BR9711363A (pt) Sintese de bis-indolilmaleimidas
EE9900568A (et) Pentaerütriidi uued derivaadid, nende valmistamine, kasutamine ja vaheühendid nende sünteesiks
ID16838A (id) Komposisi dekafluoropentana
NO20001896D0 (no) Fremgangsmõte for syntese av klorpurinmellomprodukter
BR9708718A (pt) Sínteses de aminas substituídas
AU2775597A (en) Process for the preparation of ureide derivatives and new intermediates of synthesis
FI951725A (fi) Aminoboronihappojohdannaisia, niiden valmistus ja käyttö synteesivälituotteina
AU1538397A (en) Synthesis of omeprazole-type pyridine derivatives and intermediates thereof
ID17419A (id) Komposisi dekafluoropentana
AU8868498A (en) 1,3-oxazolinyl-biphenyl derivatives, preparation method and use as synthesis intermediates
FR2747308B1 (fr) Association de margousier, de (-) hydroxycitrate et de ceramides et compositions les renfermant
FR2758326B1 (fr) Derives de pyridone, leur prepaparation et leur utilisation comme intermediaires de synthese
PT796843E (pt) Derivados de 1,25-di-hidroxi-16,22,23-trisde-hidro-colecalciferol
EE200100333A (et) Meetod 2-halo-3-nitro-4-aminopüridiini valmistamiseks ja selleks vajalike vaheühendite saamine
FI945561A (fi) Triatyyliboraanijohdannaisia, niiden valmistus ja niiden käyttö synteesivälituotteina