AU1538397A - Synthesis of omeprazole-type pyridine derivatives and intermediates thereof - Google Patents

Synthesis of omeprazole-type pyridine derivatives and intermediates thereof

Info

Publication number
AU1538397A
AU1538397A AU15383/97A AU1538397A AU1538397A AU 1538397 A AU1538397 A AU 1538397A AU 15383/97 A AU15383/97 A AU 15383/97A AU 1538397 A AU1538397 A AU 1538397A AU 1538397 A AU1538397 A AU 1538397A
Authority
AU
Australia
Prior art keywords
omeprazole
intermediates
synthesis
pyridine derivatives
type pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU15383/97A
Inventor
Michel Bekhazi
Michel Zoghbi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PDI Research Laboratories Inc
Original Assignee
PDI Research Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2168939 external-priority patent/CA2168939A1/en
Priority claimed from CA 2173820 external-priority patent/CA2173820A1/en
Application filed by PDI Research Laboratories Inc filed Critical PDI Research Laboratories Inc
Publication of AU1538397A publication Critical patent/AU1538397A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/02—Monothiocarbonic acids; Derivatives thereof
    • C07C329/04—Esters of monothiocarbonic acids
    • C07C329/06—Esters of monothiocarbonic acids having sulfur atoms of thiocarbonic groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU15383/97A 1996-02-06 1997-02-05 Synthesis of omeprazole-type pyridine derivatives and intermediates thereof Abandoned AU1538397A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CA 2168939 CA2168939A1 (en) 1996-02-06 1996-02-06 Synthesis of pharmaceutically useful pyridine derivatives
CA2168939 1996-02-06
CA 2173820 CA2173820A1 (en) 1996-04-10 1996-04-10 Synthesis of pharmaceutically useful pyridine derivatives and intermediates for such pyridine derivatives
CA2173820 1996-04-10
PCT/CA1997/000081 WO1997029103A2 (en) 1996-02-06 1997-02-05 Synthesis of omeprazole-type pyridine derivatives and intermediates thereof

Publications (1)

Publication Number Publication Date
AU1538397A true AU1538397A (en) 1997-08-28

Family

ID=25678329

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15383/97A Abandoned AU1538397A (en) 1996-02-06 1997-02-05 Synthesis of omeprazole-type pyridine derivatives and intermediates thereof

Country Status (2)

Country Link
AU (1) AU1538397A (en)
WO (1) WO1997029103A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197962B1 (en) * 1998-01-26 2001-03-06 Kuraray Co., Ltd. Method for producing 2-sulfonylpyridine derivatives and method for producing 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole derivatives
US6350876B2 (en) 1998-01-26 2002-02-26 Kuraray Co., Ltd. 4-chloro-3,5-dimethyl-2-sulfonyl pyridines
DE10140492A1 (en) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrates of optionally substituted 2- (2-pyridinyl) methylthio-1H-benzimidazoles and process for their preparation
EP1615913A2 (en) 2003-06-10 2006-01-18 Teva Pharmaceutical Industries Limited Process for preparing 2-(pyridinyl)methyl sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
US8691995B2 (en) 2004-12-16 2014-04-08 Cipla Limited Process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (en) * 1978-04-14 1979-10-15 Haessle Ab Gastric acid secretion
FR2650825B1 (en) * 1989-08-11 1991-12-06 Isochem Sa NOVEL PYRANONE, PROCESS FOR ITS PREPARATION, ITS APPLICATION TO THE PREPARATION OF A NEW PYRIDINONE AND ITS PREPARATION PROCESS
ES2026761A6 (en) * 1990-10-31 1992-05-01 Genesis Para La Investigacion A process for the preparation of omeprazol.
US5374730A (en) * 1993-11-04 1994-12-20 Torcan Chemical Ltd. Preparation of omeprazole and lansoprazole

Also Published As

Publication number Publication date
WO1997029103A3 (en) 1997-10-23
WO1997029103A2 (en) 1997-08-14

Similar Documents

Publication Publication Date Title
AU4237896A (en) Method and intermediates for the synthesis of korupensamines
AU4416497A (en) Synthesis of quinazolinone libraries and derivatives thereof
AU7644998A (en) Anti-inflammatory piperazinyl-benzyl-tetrazole derivatives and intermediates thereof
PL327998A1 (en) Novel derivatives of 19-nor-pregnene
PL329875A1 (en) Derivatives of carbolin
PL329195A1 (en) Derivatives of 6-phenylpyridol-2-amine
IL123162A0 (en) Pyridazin-3-one derivatives their use and intermediates for their production
AU3075795A (en) Anti-helicobacter acyl derivatives of azolones
AU3039995A (en) Heterocyclic derivatives of N-phenylamides
AU7129098A (en) Synthesis and use of alpha-ketoamide derivatives and arrays
AU6566098A (en) Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis
AU5381696A (en) Synthesis of bis-indolylmaleimides
AU2217797A (en) Synthesis of indolylmaleimides
AU3075595A (en) Anti-helicobacter heterocyclic derivatives of azolones
AU5923998A (en) 2-benzoylamino-3-phenylpropenamide derivatives and methods of using the same
HUP0004855A3 (en) Method for the synthesis of quinoline derivatives and intermediates
AU2454195A (en) Synthetic method of hymenialdisine and its derivatives and their synthetic intermediates, and those synthetic intermediates
AU4157097A (en) Synthesis of bisindolylmalimides
AU7022098A (en) Synthesis of pharmaceutically useful pyridine derivatives
AU6284596A (en) Production of mono-n-alkyl-dinitroalkylanilines and n-alkyl-dinitroaniline derivatives
AU1089599A (en) Synthesis of azetidine derivatives
AU1538397A (en) Synthesis of omeprazole-type pyridine derivatives and intermediates thereof
AU4877196A (en) Derivatives of 3-pyrrolidylidene-2-one-cephalosporines
AU8869098A (en) Preparation of pyridine derivatives
AU1870295A (en) Novel derivatives of tetramethylcyclopropane