EE9800248A - Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine - Google Patents

Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Info

Publication number
EE9800248A
EE9800248A EE9800248A EE9800248A EE9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A
Authority
EE
Estonia
Prior art keywords
freeze
preparation
ultrasound contrast
contrast medium
dried
Prior art date
Application number
EE9800248A
Other languages
English (en)
Estonian (et)
Inventor
Helge Gulliksen Per
Undheim Br�nden Jorunn
Kjersti Fahlvik Anne
Swaerd-Nordmo Marit
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of EE9800248A publication Critical patent/EE9800248A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
EE9800248A 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine EE9800248A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Publications (1)

Publication Number Publication Date
EE9800248A true EE9800248A (et) 1999-02-15

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800248A EE9800248A (et) 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Country Status (18)

Country Link
EP (1) EP0885016B1 (ru)
JP (1) JP4250747B2 (ru)
KR (1) KR100501863B1 (ru)
CN (1) CN1092988C (ru)
AT (1) ATE237362T1 (ru)
AU (1) AU722735B2 (ru)
CA (1) CA2246778A1 (ru)
CZ (1) CZ262698A3 (ru)
DE (1) DE69720979T2 (ru)
EA (1) EA000900B1 (ru)
EE (1) EE9800248A (ru)
ES (1) ES2197331T3 (ru)
HU (1) HUP9900812A3 (ru)
IL (1) IL125800A0 (ru)
NO (1) NO313815B1 (ru)
NZ (1) NZ331372A (ru)
PL (1) PL328309A1 (ru)
WO (1) WO1997029782A1 (ru)

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CZ28999A3 (cs) 1996-08-02 1999-07-14 Nycomed Imaging As Použití kontrastního prostředku
GB9717542D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Process
BR0112417A (pt) * 2000-07-13 2003-07-01 Daiichi Seiyaku Co Composições farmacêuticas contendo composto dds
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
ATE299378T1 (de) * 2001-01-31 2005-07-15 Bracco Research Sa Lyophilisierbares kontrastmittel, gasgefüllte mikrobläschen enthaltend
US7931595B2 (en) 2002-11-29 2011-04-26 Ge Healthcare As Ultrasound triggering method to reduce cardiac arrhythmia
WO2004069284A2 (en) * 2003-02-04 2004-08-19 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
WO2005063305A1 (en) 2003-12-22 2005-07-14 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
EP1784228B1 (en) 2004-08-18 2016-10-05 Bracco Suisse SA Gas-filled microvesicles composition for contrast imaging
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
AU2007293888B2 (en) 2006-09-05 2013-05-02 Bracco Suisse S.A. Gas-filled microvesicles with polymer-modified lipids
US8293214B2 (en) 2006-12-19 2012-10-23 Bracco Suisse S.A. Targeting and therapeutic compounds and gas-filled microvesicles comprising said compounds
JP2010539049A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト サイモシンβ４の単独、またはセクロピンＡとの組合せでの、治療剤としてのペプチドの使用
AU2008297905A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a laminin peptide as a therapeutic agent
WO2009039994A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Proadrenomedullin alone or in combination with big gastrin i as a therapeutic agent
WO2009043527A2 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Therapeutic use of human growth hormone 1-43
AU2008303942A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of BFGF 1-24 and optionally (ARG 8) vasopressin to treat eg S. pneumoniae infection
KR20100056518A (ko) 2007-09-11 2010-05-27 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드의 용도
AU2008303932A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of BPP-B as a therapeutic agent
RU2010114058A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение пептида в качестве терапевтического средства
WO2009033714A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
CA2699065A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
EP2197462A2 (en) 2007-09-11 2010-06-23 Mondobiotech Laboratories AG Use of il-1 receptor peptide, alone or in combination with d-ala-gln-octadecyl ester, as a therapeutic agent
US20100204114A1 (en) 2007-09-11 2010-08-12 Dorian Bevec Use of a galanin peptide as a therapeutic agent
EP2090322A1 (en) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of fsh receptor ligands for diagnosis and therapy of cancer
CN102202694B (zh) 2008-10-07 2014-03-12 博莱科瑞士股份有限公司 包含抗-聚合物抗体的靶向构建体和结合它们的脂质体或微泡
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
KR101783653B1 (ko) 2010-08-09 2017-10-10 브라코 스위스 에스.에이. 표적화 기체-충전 미세소포
EP2426202A1 (en) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinases as targets for anti-diabetic therapy
EP2654788B1 (en) 2010-12-24 2018-03-14 Bracco Suisse SA Gas-filled microvesicles for use as vaccine
JP6133308B2 (ja) 2011-10-21 2017-05-24 セレーター ファーマシューティカルズ インコーポレイテッド 凍結乾燥リポソーム
EP2589383A1 (en) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin FKBP subtype-specific rapamycin analogue for use in treatment of diseases
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (en) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
CN107206065A (zh) 2014-12-22 2017-09-26 博莱科瑞士股份有限公司 用作疫苗的气体填充的微囊
EP3762041A1 (en) 2018-03-07 2021-01-13 Bracco Suisse SA Preparation of size-controlled microvesicles
CN114025807A (zh) 2019-06-25 2022-02-08 博莱科瑞士股份有限公司 用于制备标准化充气微泡的冻干组合物
JP2022538769A (ja) * 2019-06-25 2022-09-06 ブラッコ・スイス・ソシエテ・アノニム 校正されたガス充填微小胞を調製するための凍結乾燥組成物
US10953023B1 (en) 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (en) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Antisense-oligonucleotides for prevention of kidney dysfunction promoted by endothelial dysfunction by ephrin-b2 suppression

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US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
JP2000506122A (ja) 2000-05-23
EA000900B1 (ru) 2000-06-26
NZ331372A (en) 2000-01-28
EP0885016A1 (en) 1998-12-23
CZ262698A3 (cs) 1999-03-17
EA199800739A1 (ru) 1999-02-25
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
CN1092988C (zh) 2002-10-23
KR100501863B1 (ko) 2005-09-27
PL328309A1 (en) 1999-01-18
HUP9900812A3 (en) 1999-11-29
ATE237362T1 (de) 2003-05-15
DE69720979T2 (de) 2004-02-26
CN1213971A (zh) 1999-04-14
NO313815B1 (no) 2002-12-09
WO1997029782A1 (en) 1997-08-21
EP0885016B1 (en) 2003-04-16
AU722735B2 (en) 2000-08-10
CA2246778A1 (en) 1997-08-21
JP4250747B2 (ja) 2009-04-08
NO983584L (no) 1998-10-16
ES2197331T3 (es) 2004-01-01
IL125800A0 (en) 1999-04-11
AU1805197A (en) 1997-09-02
DE69720979D1 (de) 2003-05-22
HUP9900812A2 (hu) 1999-07-28

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