GR1000247B - Σταθεραι λυοφιλιωμεναι διαμορφωσεις περιεχουσαι παραγοντας αναπτυξεως. - Google Patents
Σταθεραι λυοφιλιωμεναι διαμορφωσεις περιεχουσαι παραγοντας αναπτυξεως.Info
- Publication number
- GR1000247B GR1000247B GR880100618A GR880100618A GR1000247B GR 1000247 B GR1000247 B GR 1000247B GR 880100618 A GR880100618 A GR 880100618A GR 880100618 A GR880100618 A GR 880100618A GR 1000247 B GR1000247 B GR 1000247B
- Authority
- GR
- Greece
- Prior art keywords
- constant
- formulations containing
- compositions
- containing growing
- growing agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Παρέχονται σταθεραί λυοφιλιωμέναι συνθέσεις περιλαμβάνουσαι πολυπεπτιδικούς παράγοντας αναπτύξεως και θήκες (σακκίδια με τα απαραίτητα) περιέχουσαι τας συνθέσεις. Οι συνθέσεις δύνανται να περιέχουν μέσα επεκτάσεως δια λυοφιλίωσιν και επίσης δύνανται να περιέχουν υδατο-διαλυτά πολυμερή δια να προσδώσουν ιξώδες εις ανασυσταθέν διάλυμα. ω
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9881787A | 1987-09-18 | 1987-09-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
GR880100618A GR880100618A (en) | 1989-06-22 |
GR1000247B true GR1000247B (el) | 1992-05-12 |
Family
ID=22271044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR880100618A GR1000247B (el) | 1987-09-18 | 1988-09-16 | Σταθεραι λυοφιλιωμεναι διαμορφωσεις περιεχουσαι παραγοντας αναπτυξεως. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0308238A1 (el) |
JP (1) | JPH01121223A (el) |
KR (1) | KR890004721A (el) |
AU (1) | AU2223688A (el) |
DK (1) | DK516788A (el) |
GR (1) | GR1000247B (el) |
NZ (1) | NZ226170A (el) |
PT (1) | PT88538A (el) |
ZA (1) | ZA886943B (el) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2020654A1 (en) * | 1989-07-07 | 1991-01-08 | Yohko Akiyama | Stabilized fgf composition and production thereof |
JP2865320B2 (ja) * | 1989-08-07 | 1999-03-08 | 株式会社資生堂 | 固型化粧料組成物 |
US5422340A (en) * | 1989-09-01 | 1995-06-06 | Ammann; Arthur J. | TGF-βformulation for inducing bone growth |
US5188825A (en) * | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
JPH0818999B2 (ja) * | 1990-01-05 | 1996-02-28 | 藤沢薬品工業株式会社 | インシュリン様成長因子iの乾燥製剤 |
WO1991011992A1 (en) * | 1990-02-13 | 1991-08-22 | Zerega Gere S Di | Peritoneal induced medicaments |
US5374620A (en) * | 1990-06-07 | 1994-12-20 | Genentech, Inc. | Growth-promoting composition and its use |
US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
DK148790D0 (da) * | 1990-06-19 | 1990-06-19 | Novo Nordisk As | Farmaceutisk praeparat |
GB9014871D0 (en) * | 1990-07-05 | 1990-08-22 | Erba Carlo Spa | Drug delivery system for administering growth factor |
GB9015824D0 (en) * | 1990-07-18 | 1990-09-05 | Erba Carlo Spa | Stable pharmaceutical compositions containing a fibroblast growth factor |
US5714458A (en) * | 1990-07-18 | 1998-02-03 | Farmitalia Carlo Erba S.R.L. | Stable pharmaceutical compositions containing a fibroblast growth factor |
JP2926930B2 (ja) * | 1990-08-09 | 1999-07-28 | 富士ゼロックス株式会社 | 静電記録装置 |
US5197973A (en) * | 1990-12-14 | 1993-03-30 | Creative Biomolecules, Inc. | Synthetic bioadhesive |
US5206023A (en) * | 1991-01-31 | 1993-04-27 | Robert F. Shaw | Method and compositions for the treatment and repair of defects or lesions in cartilage |
DE4121043A1 (de) * | 1991-06-26 | 1993-01-07 | Merck Patent Gmbh | Knochenersatzmaterial mit fgf |
US5591709A (en) * | 1991-08-30 | 1997-01-07 | Life Medical Sciences, Inc. | Compositions and methods for treating wounds |
HUT67319A (en) * | 1991-08-30 | 1995-03-28 | Life Medical Sciences Inc | Compositions for treating wounds |
US5270300A (en) * | 1991-09-06 | 1993-12-14 | Robert Francis Shaw | Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone |
US5192743A (en) * | 1992-01-16 | 1993-03-09 | Genentech, Inc. | Reconstitutable lyophilized protein formulation |
DE4242889A1 (de) * | 1992-12-18 | 1994-06-23 | Merck Patent Gmbh | Hohlendoprothesen mit Knochenwachstumsfördernder Füllung |
US6828415B2 (en) | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
DE4305225A1 (de) * | 1993-02-19 | 1994-08-25 | Asta Medica Ag | Neues Herstellverfahren für Cetrorelix Lyophilisat |
EP0637450A3 (en) * | 1993-08-04 | 1995-04-05 | Collagen Corp | Method and composition for resuscitation of hereditary tissue. |
US6277828B1 (en) | 1993-08-20 | 2001-08-21 | Syntex (U.S.A.) Inc. | Pharmaceutical formulations of nerve growth factor |
US6288030B1 (en) | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
SE9400036D0 (sv) * | 1994-01-10 | 1994-01-10 | Pharmacia Ab | Low modecular weight hyaluronic acid |
EP0782850A4 (en) * | 1994-10-13 | 1998-03-04 | Wakamoto Pharma Co Ltd | LYOPHILIZED PREPARATION FOR PRODUCING A REVERSIBLE THERMOGELING MEDICINAL WATER-BASED |
US6063396A (en) * | 1994-10-26 | 2000-05-16 | Houston Biotechnology Incorporated | Methods and compositions for the modulation of cell proliferation and wound healing |
AU4027601A (en) * | 1995-07-11 | 2001-07-26 | Snow Brand Milk Products Co., Ltd. | Lyophilized HGF preparations |
JP3927248B2 (ja) * | 1995-07-11 | 2007-06-06 | 第一製薬株式会社 | Hgf凍結乾燥製剤 |
GB9608222D0 (en) * | 1996-04-20 | 1996-06-26 | Innovative Tech Ltd | Dehydrated hydrogels |
US6569172B2 (en) | 1996-08-30 | 2003-05-27 | Verigen Transplantation Service International (Vtsi) | Method, instruments, and kit for autologous transplantation |
US5989269A (en) | 1996-08-30 | 1999-11-23 | Vts Holdings L.L.C. | Method, instruments and kit for autologous transplantation |
JP4388602B2 (ja) * | 1997-02-07 | 2009-12-24 | ストライカー コーポレイション | マトリクスを含まない骨形成デバイス、移植片、およびその使用方法 |
US6284282B1 (en) | 1998-04-29 | 2001-09-04 | Genentech, Inc. | Method of spray freeze drying proteins for pharmaceutical administration |
MXPA01001460A (es) | 1998-08-14 | 2005-06-06 | Verigen Transplantation Serv | Metodos, instrumentos y materiales para el transplante de celulas condrociticas. |
JP2002539172A (ja) * | 1999-03-17 | 2002-11-19 | ノバルティス アクチエンゲゼルシャフト | Tgf−ベータを含む医薬組成物 |
GB9914412D0 (en) * | 1999-06-22 | 1999-08-18 | Worrall Eric E | Method for the preservation of viruses,bacteria and biomolecules |
MXPA02000128A (es) * | 1999-06-22 | 2002-06-21 | Res Dev Foundation | Material mejorado de heridas para mejorar curacion de heridas. |
CA2435146C (en) | 2001-01-25 | 2011-03-29 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Formulation of boronic acid compounds |
US20030068416A1 (en) * | 2001-09-24 | 2003-04-10 | Wilson Burgess | Method of lyophylization to reduce solvent content and enhance product recovery |
TWI436789B (zh) | 2008-01-21 | 2014-05-11 | Intervet Int Bv | 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包 |
US9757418B1 (en) | 2009-07-09 | 2017-09-12 | Pgfx Patent Holdings, Llc | Process for removing growth factors from platelets |
US8734854B2 (en) * | 2009-07-09 | 2014-05-27 | Orogen Biosciences Inc. | Process for removing growth factors from platelets |
US9688735B2 (en) | 2010-08-20 | 2017-06-27 | Wyeth Llc | Designer osteogenic proteins |
ES2893239T3 (es) | 2015-04-21 | 2022-02-08 | Staidson Beijing Biopharmaceuticals Co Ltd | Composición de factor de crecimiento nervioso y polvo de inyección |
CN115869468A (zh) * | 2018-12-28 | 2023-03-31 | 黄玲惠 | 生物支架和用于制备其的方法 |
CN113975193A (zh) * | 2021-11-12 | 2022-01-28 | 广州科妍化妆品有限公司 | 一种冻干面膜及其制备方法 |
CN117205162B (zh) * | 2023-09-12 | 2024-06-25 | 上海腾瑞制药股份有限公司 | 一种重组人酸性成纤维细胞生长因子冻干制剂的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55500053A (el) * | 1978-01-16 | 1980-01-31 | ||
US4469228A (en) * | 1983-05-31 | 1984-09-04 | Schering Corporation | Interferon kit |
US4444760A (en) * | 1983-06-17 | 1984-04-24 | Merck & Co., Inc. | Purification and characterization of a protein fibroblast growth factor |
JPS60258125A (ja) * | 1984-06-06 | 1985-12-20 | Hayashibara Biochem Lab Inc | 蛋白性生理活性物質を含有する水溶性乾燥物 |
EP0193917A3 (en) * | 1985-03-06 | 1987-09-23 | American Cyanamid Company | Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration |
-
1988
- 1988-09-13 NZ NZ226170A patent/NZ226170A/en unknown
- 1988-09-14 AU AU22236/88A patent/AU2223688A/en not_active Abandoned
- 1988-09-16 ZA ZA886943A patent/ZA886943B/xx unknown
- 1988-09-16 GR GR880100618A patent/GR1000247B/el unknown
- 1988-09-16 JP JP63232101A patent/JPH01121223A/ja active Pending
- 1988-09-16 PT PT88538A patent/PT88538A/pt not_active Application Discontinuation
- 1988-09-16 KR KR1019880011969A patent/KR890004721A/ko not_active Application Discontinuation
- 1988-09-16 EP EP88308573A patent/EP0308238A1/en not_active Withdrawn
- 1988-09-16 DK DK516788A patent/DK516788A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0308238A1 (en) | 1989-03-22 |
JPH01121223A (ja) | 1989-05-12 |
KR890004721A (ko) | 1989-05-09 |
NZ226170A (en) | 1990-07-26 |
DK516788A (da) | 1989-03-19 |
PT88538A (pt) | 1989-07-31 |
ZA886943B (en) | 1990-05-30 |
GR880100618A (en) | 1989-06-22 |
AU2223688A (en) | 1989-03-23 |
DK516788D0 (da) | 1988-09-16 |
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