EE9800248A - Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine - Google Patents

Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Info

Publication number
EE9800248A
EE9800248A EE9800248A EE9800248A EE9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A
Authority
EE
Estonia
Prior art keywords
freeze
preparation
ultrasound contrast
contrast medium
dried
Prior art date
Application number
EE9800248A
Other languages
English (en)
Estonian (et)
Inventor
Helge Gulliksen Per
Undheim Br�nden Jorunn
Kjersti Fahlvik Anne
Swaerd-Nordmo Marit
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of EE9800248A publication Critical patent/EE9800248A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EE9800248A 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine EE9800248A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Publications (1)

Publication Number Publication Date
EE9800248A true EE9800248A (et) 1999-02-15

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800248A EE9800248A (et) 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Country Status (18)

Country Link
EP (1) EP0885016B1 (xx)
JP (1) JP4250747B2 (xx)
KR (1) KR100501863B1 (xx)
CN (1) CN1092988C (xx)
AT (1) ATE237362T1 (xx)
AU (1) AU722735B2 (xx)
CA (1) CA2246778A1 (xx)
CZ (1) CZ262698A3 (xx)
DE (1) DE69720979T2 (xx)
EA (1) EA000900B1 (xx)
EE (1) EE9800248A (xx)
ES (1) ES2197331T3 (xx)
HU (1) HUP9900812A3 (xx)
IL (1) IL125800A0 (xx)
NO (1) NO313815B1 (xx)
NZ (1) NZ331372A (xx)
PL (1) PL328309A1 (xx)
WO (1) WO1997029782A1 (xx)

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GB9717542D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Process
AU2001271037A1 (en) * 2000-07-13 2002-01-30 Daiichi Pharmaceutical Co., Ltd. Pharmaceutical compositions containing dds compounds
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
DK1228770T3 (da) * 2001-01-31 2005-11-07 Bracco Int Bv Törret kontrastmiddel
WO2004049950A1 (en) 2002-11-29 2004-06-17 Amersham Health As Ultrasound triggering method
ATE480263T1 (de) 2003-02-04 2010-09-15 Bracco Suisse Sa Ultraschall kontrastmittel und verfahren zur erstellung
US9750821B2 (en) 2003-12-22 2017-09-05 Bracco Suisse S.A. Gas-filled microvesicle assembly for contrast imaging
EP1784228B1 (en) 2004-08-18 2016-10-05 Bracco Suisse SA Gas-filled microvesicles composition for contrast imaging
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
EP2061517B1 (en) 2006-09-05 2010-06-02 Bracco Research S.A. Gas-filled microvesicles with polymer-modified lipids
EP2117603A2 (en) 2006-12-19 2009-11-18 Bracco International B.V. Targeting and therapeutic compounds and gas-filled microvesicles comprising said compounds
WO2009046859A2 (en) 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Use of af12198 and dago as therapeutic agents
JP2010539007A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 治療剤としてのペプチドの使用
RU2010114012A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) ПРИМЕНЕНИЕ Tyr-W-Mif-1 И УРОКОРТИНА 2 В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКИХ СРЕДСТВ
WO2009033792A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Gamma 1 msh alone or in combination with pentagastrin as a therapeutic agent
WO2009040036A2 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
US20100210558A1 (en) 2007-09-11 2010-08-19 Dorian Bevec Minigastrin as a therapeutic agent
CA2698751A1 (en) 2007-09-11 2009-04-02 Dorian Bevec Use of a peptide as a therapeutic agent
CA2698783A1 (en) 2007-09-11 2009-03-19 Dorian Bevec Use of a peptide as a therapeutic agent
US20100184676A1 (en) 2007-09-11 2010-07-22 Dorian Bevec Use of a peptide as a therapeutic agent
WO2009039996A2 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
RU2010114058A (ru) 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение пептида в качестве терапевтического средства
KR20100058554A (ko) 2007-09-11 2010-06-03 몬도바이오테크 래보래토리즈 아게 치료제로서의 망막 콜린성 뉴런을 위한 신경영양성 인자 （ｎｆｒｃｎ） 및 융모성 고나도트로핀―베타 （１０９―１４５）의 용도
EP2090322A1 (en) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of fsh receptor ligands for diagnosis and therapy of cancer
AU2009301141B2 (en) 2008-10-07 2015-08-27 Bracco Suisse S.A. Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
AU2011288511B2 (en) 2010-08-09 2016-01-07 Bracco Suisse Sa Targeted gas-filled microvesicles
EP2426202A1 (en) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinases as targets for anti-diabetic therapy
BR112013016244B1 (pt) 2010-12-24 2021-12-21 Bracco Suisse Sa Formulação farmacêutica compreendendo microvesículas cheias de gás e precursor da mesma
CN108853031A (zh) 2011-10-21 2018-11-23 切拉托尔制药公司 冻干脂质体
EP2589383A1 (en) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin FKBP subtype-specific rapamycin analogue for use in treatment of diseases
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) * 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (en) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
CN107206065A (zh) 2014-12-22 2017-09-26 博莱科瑞士股份有限公司 用作疫苗的气体填充的微囊
JP2021516684A (ja) 2018-03-07 2021-07-08 ブラッコ・スイス・ソシエテ・アノニム サイズが制御された微小胞の調製
WO2020260423A1 (en) * 2019-06-25 2020-12-30 Bracco Suisse Sa Freeze-dried composition for preparing calibrated gas-filled microvesicles
DK3990032T3 (da) 2019-06-25 2023-12-18 Bracco Suisse Sa Frysetørret sammensætning til fremstilling af kalibrerede gasfyldte mikrovesikler
US10953023B1 (en) 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (en) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Antisense-oligonucleotides for prevention of kidney dysfunction promoted by endothelial dysfunction by ephrin-b2 suppression

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US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
KR100501863B1 (ko) 2005-09-27
CN1092988C (zh) 2002-10-23
EP0885016A1 (en) 1998-12-23
NO983584L (no) 1998-10-16
EA000900B1 (ru) 2000-06-26
ES2197331T3 (es) 2004-01-01
CZ262698A3 (cs) 1999-03-17
NO313815B1 (no) 2002-12-09
HUP9900812A2 (hu) 1999-07-28
CA2246778A1 (en) 1997-08-21
EA199800739A1 (ru) 1999-02-25
ATE237362T1 (de) 2003-05-15
JP4250747B2 (ja) 2009-04-08
IL125800A0 (en) 1999-04-11
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
NZ331372A (en) 2000-01-28
PL328309A1 (en) 1999-01-18
DE69720979T2 (de) 2004-02-26
AU722735B2 (en) 2000-08-10
AU1805197A (en) 1997-09-02
HUP9900812A3 (en) 1999-11-29
WO1997029782A1 (en) 1997-08-21
JP2000506122A (ja) 2000-05-23
CN1213971A (zh) 1999-04-14
DE69720979D1 (de) 2003-05-22
EP0885016B1 (en) 2003-04-16

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