EE9500049A - Bensoksasolüül- ja bensotiasolüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimitena ja nimetatud ühendeid sisaldavad ravimid - Google Patents

Bensoksasolüül- ja bensotiasolüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimitena ja nimetatud ühendeid sisaldavad ravimid

Info

Publication number
EE9500049A
EE9500049A EE9500049A EE9500049A EE9500049A EE 9500049 A EE9500049 A EE 9500049A EE 9500049 A EE9500049 A EE 9500049A EE 9500049 A EE9500049 A EE 9500049A EE 9500049 A EE9500049 A EE 9500049A
Authority
EE
Estonia
Prior art keywords
alkyl
substd
opt
alkoxy
acyl
Prior art date
Application number
EE9500049A
Other languages
English (en)
Estonian (et)
Inventor
H�bich Dieter
Riedl Bernd
Ruppelt Martin
Stolle Andreas
Wild Hanno
Endermann Rainer
Bremm Klaus-Dieter
Kroll Hein-Peter
Labischinski Harald
Schaller Klaus
Werling Hans-Otto
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of EE9500049A publication Critical patent/EE9500049A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
EE9500049A 1994-08-03 1995-08-02 Bensoksasolüül- ja bensotiasolüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimitena ja nimetatud ühendeid sisaldavad ravimid EE9500049A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427475 1994-08-03
DE19514313A DE19514313A1 (de) 1994-08-03 1995-04-18 Benzoxazolyl- und Benzothiazolyloxazolidinone

Publications (1)

Publication Number Publication Date
EE9500049A true EE9500049A (et) 1996-02-15

Family

ID=25938925

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500049A EE9500049A (et) 1994-08-03 1995-08-02 Bensoksasolüül- ja bensotiasolüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimitena ja nimetatud ühendeid sisaldavad ravimid

Country Status (30)

Country Link
US (1) US5529998A (ko)
EP (1) EP0697412B1 (ko)
JP (1) JPH0881463A (ko)
KR (1) KR960007585A (ko)
CN (1) CN1122803A (ko)
AT (1) ATE188698T1 (ko)
AU (1) AU698939B2 (ko)
BG (1) BG62404B1 (ko)
CA (1) CA2155092A1 (ko)
CO (1) CO4410392A1 (ko)
CZ (1) CZ198895A3 (ko)
DE (2) DE19514313A1 (ko)
DZ (1) DZ1920A1 (ko)
EE (1) EE9500049A (ko)
FI (1) FI953665A (ko)
HR (1) HRP950428A2 (ko)
HU (1) HUT75037A (ko)
IL (1) IL114784A (ko)
MA (1) MA23638A1 (ko)
NO (1) NO305701B1 (ko)
NZ (1) NZ272674A (ko)
PE (1) PE2796A1 (ko)
PL (1) PL309848A1 (ko)
RO (1) RO115263B1 (ko)
SK (1) SK97495A3 (ko)
SV (1) SV1995000045A (ko)
TN (1) TNSN95088A1 (ko)
TW (1) TW352386B (ko)
YU (1) YU51095A (ko)
ZA (1) ZA956445B (ko)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) * 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) * 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
KR20010015910A (ko) 1998-01-23 2001-02-26 로렌스 티. 마이젠헬더 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법
KR20010052615A (ko) 1998-06-05 2001-06-25 다비드 에 질레스 옥사졸리디논 유도체, 이것의 제조 방법 및 이것을함유하는 약학 조성물
GB9815880D0 (en) 1998-07-21 1998-09-16 Pfizer Ltd Heterocycles
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
AU1045300A (en) * 1998-11-17 2000-06-05 Bayer Aktiengesellschaft Novel heterocyclyl-substituted oxazolidone derivatives
WO2000045177A1 (en) 1999-01-27 2000-08-03 Pharmacia & Upjohn Company Assays for modulators of elongation factor p activity
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
MY127336A (en) 2000-03-22 2006-11-30 Upjohn Co Container for linezolid iv solution
US6514529B2 (en) 2000-03-22 2003-02-04 Pharmacia & Upjohn Company Oxazolidinone tablet formulation
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2004501965A (ja) 2000-06-30 2004-01-22 ファルマシア・アンド・アップジョン・カンパニー 細菌感染を治療するための組成物および方法
MY138797A (en) * 2000-12-15 2009-07-31 Vertex Pharma Bacterial gyrase inhibitors and uses thereof
ATE319710T1 (de) 2000-12-21 2006-03-15 Pharmacia & Upjohn Co Llc Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
CA2476545A1 (en) * 2002-03-29 2003-10-16 Pharmacia & Upjohn Company Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
MXPA04012628A (es) 2002-06-13 2005-03-23 Patricia Olivershaffer DERIVADOS Y COMPUESTOS RELACIONADOS DEL áCIDO 2-UREIDO-6-HETEROARIL-3H-BENZOIMIDAZOL-4-CARBOXILICO COMO INHIBIDORES DE GIRASA Y/O TOPOISOMERASA IV PARA EL TRATAMIENTO DE INFECCIONES BACTERIALES.
CA2491287A1 (en) * 2002-08-12 2004-02-19 Pharmacia & Upjohn Company N-aryl-2-oxazolidinones and their derivatives
AU2002339721A1 (en) * 2002-09-20 2004-04-08 Lupin Limited Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents
BR0316483A (pt) * 2002-11-21 2005-10-11 Upjohn Co Derivados de n-(4-(piperazin-1-il)-fenil-2-oxazolidinona-5-carboxami da e compostos relacionados como agentes antibacterianos
US7582635B2 (en) * 2002-12-24 2009-09-01 Purdue Pharma, L.P. Therapeutic agents useful for treating pain
US7569591B2 (en) * 2003-01-31 2009-08-04 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7582641B2 (en) 2003-01-31 2009-09-01 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US7618974B2 (en) * 2003-01-31 2009-11-17 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
US8193352B2 (en) * 2003-01-31 2012-06-05 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
BRPI0407304A (pt) * 2003-02-07 2006-01-10 Warner Lambert Co Agentes antibacterianos
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
EP1660488A1 (en) * 2003-08-25 2006-05-31 Warner-Lambert Company LLC Novel antimicrobial aryloxazolidinone compounds
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
US20060004090A1 (en) * 2004-07-01 2006-01-05 Roberts William J Forskolin compositions and methods for administration
CA2637811A1 (en) * 2006-02-01 2007-08-09 Pfizer Products Inc. Benzisoxazole oxazolidinones as antibacterial agents
JP5161070B2 (ja) 2006-03-31 2013-03-13 財団法人乙卯研究所 ヘテロ環を有する新規化合物
MX2009011601A (es) 2007-04-27 2009-11-10 Purdue Pharma Lp Agentes terapeuticos utiles para tratar el dolor.
PL2142529T3 (pl) * 2007-04-27 2014-06-30 Purdue Pharma Lp Antagoniści trpv1 i ich zastosowania
EP2669283A1 (en) 2007-10-02 2013-12-04 Shionogi&Co., Ltd. Oxazolidinone derivative having 7-membered hetero ring
US8349826B2 (en) * 2008-02-22 2013-01-08 Actelion Pharmaceuticals Ltd. Oxazolidinone derivatives
US8703962B2 (en) * 2008-10-24 2014-04-22 Purdue Pharma L.P. Monocyclic compounds and their use as TRPV1 ligands
US8759362B2 (en) * 2008-10-24 2014-06-24 Purdue Pharma L.P. Bicycloheteroaryl compounds and their use as TRPV1 ligands
AU2012205420B2 (en) 2011-01-14 2016-12-08 Spero Therapeutics, Inc. Process of making gyrase and topoisomerase IV inhibitors
AU2012205419B2 (en) 2011-01-14 2016-12-15 Spero Therapeutics, Inc. Solid forms of gyrase inhibitor (R)-1-ethyl-3-[6-fluoro-5-[2-(1-hydroxy-1-methyl-ethyl) pyrimidin-5-yl]-7-(tetrahydrofuran-2-yl)-1H-benzimidazol-2-yl]urea
TW201309676A (zh) 2011-01-14 2013-03-01 Vertex Pharma 旋轉酶抑制劑（ｒ）－１－乙基－３－［５－［２－（１－羥基－１－甲基－乙基）嘧啶－５－基］－７－（四氫呋喃－２－基］－１ｈ－苯并咪唑－２－基］脲之固體形式
EP2663557B1 (en) 2011-01-14 2015-05-27 Vertex Pharmaceuticals Incorporated Pyrimidine gyrase and topoisomerase iv inhibitors
JP5977344B2 (ja) 2011-06-20 2016-08-24 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ ジャイレースおよびトポイソメラーゼ阻害剤のリン酸エステル
RU2621708C2 (ru) 2011-06-22 2017-06-07 ПУРДЬЮ ФАРМА Эл. Пи. Антагонисты trpv1, включающие дигидроксигруппу в качестве заместителя, и их применение
US9394293B2 (en) 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
WO2014014845A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Combination therapy comprising|1 -ethyl-3-[5-[2-{1 -hydroxy-1 -methyl-ethyl}pyrimidin-5-yl]-7-(tetra hydrofuran-2-|yl}-1 h-benzimidazol-2-yl]urea and derivatives thereof to treat mycobacterium|diseases
US9018216B2 (en) 2012-07-18 2015-04-28 Vertex Pharmaceuticals Incorporated Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705799A (en) 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
GB8504871D0 (en) * 1985-02-26 1985-03-27 Ici Plc Heterocyclic compounds
US4921869A (en) 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4965268A (en) 1987-10-09 1990-10-23 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
US4801600A (en) 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
US5254577A (en) 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
WO1990002744A1 (en) * 1988-09-15 1990-03-22 The Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
JP2669579B2 (ja) * 1991-10-23 1997-10-29 エーザイ株式会社 オキサゾリドン誘導体
JP3176626B2 (ja) * 1991-11-01 2001-06-18 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤として有用な置換アリール−およびヘテロアリールフェニルオキサゾリジノン類

Also Published As

Publication number Publication date
HUT75037A (en) 1997-03-28
IL114784A (en) 1999-10-28
US5529998A (en) 1996-06-25
SK97495A3 (en) 1996-06-05
YU51095A (sh) 1998-07-10
HU9502295D0 (en) 1995-09-28
CZ198895A3 (en) 1996-02-14
PL309848A1 (en) 1996-02-05
HRP950428A2 (en) 1997-08-31
CO4410392A1 (es) 1997-01-09
EP0697412A1 (de) 1996-02-21
PE2796A1 (es) 1996-03-23
AU698939B2 (en) 1998-11-12
KR960007585A (ko) 1996-03-22
NO305701B1 (no) 1999-07-12
FI953665A (fi) 1996-02-04
MA23638A1 (fr) 1996-04-01
CN1122803A (zh) 1996-05-22
NO953045D0 (no) 1995-08-02
ZA956445B (en) 1996-03-22
NZ272674A (en) 1997-02-24
TNSN95088A1 (fr) 1996-02-06
RO115263B1 (ro) 1999-12-30
NO953045L (no) 1996-02-05
DE19514313A1 (de) 1996-02-08
JPH0881463A (ja) 1996-03-26
DZ1920A1 (fr) 2002-02-17
TW352386B (en) 1999-02-11
BG62404B1 (bg) 1999-10-29
AU2723095A (en) 1996-02-15
BG99833A (bg) 1996-02-28
CA2155092A1 (en) 1996-02-04
IL114784A0 (en) 1995-11-27
DE59507595D1 (de) 2000-02-17
FI953665A0 (fi) 1995-08-01
SV1995000045A (es) 1996-06-17
ATE188698T1 (de) 2000-01-15
EP0697412B1 (de) 2000-01-12

Similar Documents

Publication Publication Date Title
EE9500049A (et) Bensoksasolüül- ja bensotiasolüüloksasolidinoonid, nende valmistamismeetod, kasutamine ravimitena ja nimetatud ühendeid sisaldavad ravimid
BR9404831A (pt) Composto,formulação farmacêutica e processo de preparação de um composto
DZ1467A1 (fr) Dérivés d'acides amines.
NO305206B1 (no) Oksazolidinonkarboksylsyrederivater, farmas°ytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler
NO306991B1 (no) Alkenylbenzoylguanidinderivater, farmasoeytiske preparater som inneholder slike, samt anvendelse av forbindelsene til fremstilling av legemidler
HUT76480A (en) Alkyl-5-methyl-sulphonyl-benzoyl-guanidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them
NO972312D0 (no) Svovelholdige, heterocykliske bradykininantagonister, fremgangsmåte for fremstilling derav samt anvendelse av forbindelsene
IL119054A0 (en) Substituted 4H-pyrans their preparation and pharmaceutical compositions containing them
DE3366181D1 (en) 2-aminomethyl-6-sulfamoylphenol derivatives, process for their preparation, their use and pharmaceutical preparations based on these compounds
ES2189323T3 (es) Procedimiento para la preparacion de 3-amino-2-oxo-pirrolidinas, productos intermedios y su utilizacion.
NO307998B1 (no) Cykloheksadienderivater, fremgangsmÕte for fremstilling av forbindelsene, anvendelse av forbindelsene for fremstilling av legemidler samt de derved oppnÕdde legemidlene