EE200100403A - Indooli derivaadid ja nende kasutamine MCP-1 antagonistidena - Google Patents

Indooli derivaadid ja nende kasutamine MCP-1 antagonistidena

Info

Publication number
EE200100403A
EE200100403A EEP200100403A EEP200100403A EE200100403A EE 200100403 A EE200100403 A EE 200100403A EE P200100403 A EEP200100403 A EE P200100403A EE P200100403 A EEP200100403 A EE P200100403A EE 200100403 A EE200100403 A EE 200100403A
Authority
EE
Estonia
Prior art keywords
mcp
antagonists
indole derivatives
indole
derivatives
Prior art date
Application number
EEP200100403A
Other languages
English (en)
Estonian (et)
Inventor
Wellington Faull Alan
Grant Kettle Jason
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200100403A publication Critical patent/EE200100403A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EEP200100403A 1999-02-05 2000-01-31 Indooli derivaadid ja nende kasutamine MCP-1 antagonistidena EE200100403A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9902461.4A GB9902461D0 (en) 1999-02-05 1999-02-05 Chemical compounds
PCT/GB2000/000265 WO2000046196A1 (en) 1999-02-05 2000-01-31 Indole derivatives and their use as mcp-1 antagonists

Publications (1)

Publication Number Publication Date
EE200100403A true EE200100403A (et) 2002-10-15

Family

ID=10847084

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100403A EE200100403A (et) 1999-02-05 2000-01-31 Indooli derivaadid ja nende kasutamine MCP-1 antagonistidena

Country Status (27)

Country Link
US (1) US6737435B1 (enExample)
EP (1) EP1150952B1 (enExample)
JP (1) JP2002536359A (enExample)
KR (1) KR20010094755A (enExample)
CN (1) CN1339025A (enExample)
AR (1) AR022461A1 (enExample)
AT (1) ATE280757T1 (enExample)
AU (1) AU770856B2 (enExample)
BR (1) BR0007984A (enExample)
CA (1) CA2356898A1 (enExample)
CZ (1) CZ20012807A3 (enExample)
DE (1) DE60015296T2 (enExample)
EE (1) EE200100403A (enExample)
GB (1) GB9902461D0 (enExample)
HU (1) HUP0105079A3 (enExample)
ID (1) ID30401A (enExample)
IL (1) IL144611A0 (enExample)
IS (1) IS5980A (enExample)
MY (1) MY133209A (enExample)
NO (1) NO20013809L (enExample)
NZ (1) NZ512680A (enExample)
PL (1) PL350184A1 (enExample)
RU (1) RU2235090C2 (enExample)
SK (1) SK11152001A3 (enExample)
TR (1) TR200102233T2 (enExample)
WO (1) WO2000046196A1 (enExample)
ZA (1) ZA200105311B (enExample)

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EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
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Also Published As

Publication number Publication date
NZ512680A (en) 2003-11-28
TR200102233T2 (tr) 2001-12-21
NO20013809D0 (no) 2001-08-03
HUP0105079A2 (hu) 2002-04-29
AR022461A1 (es) 2002-09-04
CN1339025A (zh) 2002-03-06
MY133209A (en) 2007-10-31
DE60015296T2 (de) 2006-02-02
IL144611A0 (en) 2002-05-23
US6737435B1 (en) 2004-05-18
WO2000046196A1 (en) 2000-08-10
RU2235090C2 (ru) 2004-08-27
EP1150952B1 (en) 2004-10-27
GB9902461D0 (en) 1999-03-24
DE60015296D1 (de) 2004-12-02
CA2356898A1 (en) 2000-08-10
SK11152001A3 (sk) 2001-12-03
JP2002536359A (ja) 2002-10-29
PL350184A1 (en) 2002-11-18
HUP0105079A3 (en) 2002-11-28
AU2121300A (en) 2000-08-25
AU770856B2 (en) 2004-03-04
CZ20012807A3 (cs) 2001-10-17
EP1150952A1 (en) 2001-11-07
RU2001124567A (ru) 2004-01-10
BR0007984A (pt) 2001-11-06
ZA200105311B (en) 2002-09-27
ATE280757T1 (de) 2004-11-15
NO20013809L (no) 2001-10-02
IS5980A (is) 2001-06-26
KR20010094755A (ko) 2001-11-01
ID30401A (id) 2001-11-29

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