BR0007984A - Composto, processo para preparar um composto, e, composição farmacêutica - Google Patents

Composto, processo para preparar um composto, e, composição farmacêutica

Info

Publication number
BR0007984A
BR0007984A BR0007984-7A BR0007984A BR0007984A BR 0007984 A BR0007984 A BR 0007984A BR 0007984 A BR0007984 A BR 0007984A BR 0007984 A BR0007984 A BR 0007984A
Authority
BR
Brazil
Prior art keywords
compound
chlorophenyl
pharmaceutical composition
halo
methoxy
Prior art date
Application number
BR0007984-7A
Other languages
English (en)
Portuguese (pt)
Inventor
Alan Wellington Faull
Jason Grant Kettle
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0007984A publication Critical patent/BR0007984A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BR0007984-7A 1999-02-05 2000-01-31 Composto, processo para preparar um composto, e, composição farmacêutica BR0007984A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9902461.4A GB9902461D0 (en) 1999-02-05 1999-02-05 Chemical compounds
PCT/GB2000/000265 WO2000046196A1 (en) 1999-02-05 2000-01-31 Indole derivatives and their use as mcp-1 antagonists

Publications (1)

Publication Number Publication Date
BR0007984A true BR0007984A (pt) 2001-11-06

Family

ID=10847084

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0007984-7A BR0007984A (pt) 1999-02-05 2000-01-31 Composto, processo para preparar um composto, e, composição farmacêutica

Country Status (27)

Country Link
US (1) US6737435B1 (enExample)
EP (1) EP1150952B1 (enExample)
JP (1) JP2002536359A (enExample)
KR (1) KR20010094755A (enExample)
CN (1) CN1339025A (enExample)
AR (1) AR022461A1 (enExample)
AT (1) ATE280757T1 (enExample)
AU (1) AU770856B2 (enExample)
BR (1) BR0007984A (enExample)
CA (1) CA2356898A1 (enExample)
CZ (1) CZ20012807A3 (enExample)
DE (1) DE60015296T2 (enExample)
EE (1) EE200100403A (enExample)
GB (1) GB9902461D0 (enExample)
HU (1) HUP0105079A3 (enExample)
ID (1) ID30401A (enExample)
IL (1) IL144611A0 (enExample)
IS (1) IS5980A (enExample)
MY (1) MY133209A (enExample)
NO (1) NO20013809L (enExample)
NZ (1) NZ512680A (enExample)
PL (1) PL350184A1 (enExample)
RU (1) RU2235090C2 (enExample)
SK (1) SK11152001A3 (enExample)
TR (1) TR200102233T2 (enExample)
WO (1) WO2000046196A1 (enExample)
ZA (1) ZA200105311B (enExample)

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GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000625D0 (en) * 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
GB0000626D0 (en) * 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
CN1505613A (zh) 2000-10-10 2004-06-16 ʷ��˿�������ȳ�ķ���޹�˾ 取代的吲哚、含这类吲哚的药物组合物及它们作为PPAR-γ结合剂的用途
AU2002241724A1 (en) 2000-12-20 2002-07-01 Bristol-Myers Squibb Company Diamines as modulators of chemokine receptor activity
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US7842693B2 (en) 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
KR101255356B1 (ko) 2002-06-12 2013-04-17 케모센트릭스, 인크. 염증 및 면역 질병의 치료를 위한 ｃｃｒ１ 길항물질로서사용하기 위한 1-아릴-4-치환된 피페라진 유도체
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US7291615B2 (en) 2003-05-01 2007-11-06 Bristol-Myers Squibb Company Cyclic derivatives as modulators of chemokine receptor activity
US7230133B2 (en) 2003-05-01 2007-06-12 Bristol-Myers Squibb Company Malonamides and malonamide derivatives as modulators of chemokine receptor activity
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US7230022B2 (en) 2004-02-19 2007-06-12 Bristol-Myers Squibb Company Substituted fused bicyclic amines as modulators of chemokine receptor activity
US7288563B2 (en) 2004-02-19 2007-10-30 Bristol-Myers Squibb Company Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity
US7381738B2 (en) 2004-02-19 2008-06-03 Bristol-Myers Squibb Company Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity
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CA2644368A1 (en) 2006-03-10 2007-09-20 Ono Pharmaceutical Co., Ltd. Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
JP5257068B2 (ja) 2006-05-16 2013-08-07 小野薬品工業株式会社 保護されていてもよい酸性基を含有する化合物およびその用途
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US20090325992A1 (en) 2006-07-31 2009-12-31 Ono Pharmaceutical Co., Ltd. Compound having cyclic group bound thereto through spiro binding and use thereof
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JP5379692B2 (ja) 2006-11-09 2013-12-25 プロビオドルグ エージー 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体
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BR112012022478B1 (pt) 2010-03-10 2021-09-21 Probiodrug Ag Inibidores heterocíclicos de glutaminil ciclase (qc, ec 2.3.2.5), seu processo de preparação, e composição farmacêutica
JP5945532B2 (ja) 2010-04-21 2016-07-05 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
KR101350077B1 (ko) * 2010-12-13 2014-01-14 한국화학연구원 신규한 3-인돌리논 유도체 및 이를 포함하는 조성물
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
EP3551034A1 (en) 2016-12-07 2019-10-16 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CA3045310A1 (en) 2016-12-14 2018-06-21 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
WO2020106704A2 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
EP4450494A1 (en) * 2023-04-20 2024-10-23 Consejo Superior De Investigaciones Científicas Indole derivatives as histone deacetylase (hdac) inhibitors for the treatment of cancer

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Also Published As

Publication number Publication date
NZ512680A (en) 2003-11-28
TR200102233T2 (tr) 2001-12-21
NO20013809D0 (no) 2001-08-03
HUP0105079A2 (hu) 2002-04-29
AR022461A1 (es) 2002-09-04
CN1339025A (zh) 2002-03-06
MY133209A (en) 2007-10-31
DE60015296T2 (de) 2006-02-02
IL144611A0 (en) 2002-05-23
US6737435B1 (en) 2004-05-18
WO2000046196A1 (en) 2000-08-10
RU2235090C2 (ru) 2004-08-27
EP1150952B1 (en) 2004-10-27
GB9902461D0 (en) 1999-03-24
DE60015296D1 (de) 2004-12-02
CA2356898A1 (en) 2000-08-10
SK11152001A3 (sk) 2001-12-03
JP2002536359A (ja) 2002-10-29
PL350184A1 (en) 2002-11-18
HUP0105079A3 (en) 2002-11-28
AU2121300A (en) 2000-08-25
AU770856B2 (en) 2004-03-04
CZ20012807A3 (cs) 2001-10-17
EP1150952A1 (en) 2001-11-07
RU2001124567A (ru) 2004-01-10
ZA200105311B (en) 2002-09-27
ATE280757T1 (de) 2004-11-15
NO20013809L (no) 2001-10-02
IS5980A (is) 2001-06-26
EE200100403A (et) 2002-10-15
KR20010094755A (ko) 2001-11-01
ID30401A (id) 2001-11-29

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