ATE280757T1 - Indolderivate und ihre verwendung als mcp-1 rezeptor antagonisten - Google Patents

Indolderivate und ihre verwendung als mcp-1 rezeptor antagonisten

Info

Publication number
ATE280757T1
ATE280757T1 AT00901259T AT00901259T ATE280757T1 AT E280757 T1 ATE280757 T1 AT E280757T1 AT 00901259 T AT00901259 T AT 00901259T AT 00901259 T AT00901259 T AT 00901259T AT E280757 T1 ATE280757 T1 AT E280757T1
Authority
AT
Austria
Prior art keywords
mcp
receptor antagonists
indole derivatives
indole
derivatives
Prior art date
Application number
AT00901259T
Other languages
English (en)
Inventor
Alan Wellington Faull
Jason Grant Kettle
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE280757T1 publication Critical patent/ATE280757T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT00901259T 1999-02-05 2000-01-31 Indolderivate und ihre verwendung als mcp-1 rezeptor antagonisten ATE280757T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9902461.4A GB9902461D0 (en) 1999-02-05 1999-02-05 Chemical compounds
PCT/GB2000/000265 WO2000046196A1 (en) 1999-02-05 2000-01-31 Indole derivatives and their use as mcp-1 antagonists

Publications (1)

Publication Number Publication Date
ATE280757T1 true ATE280757T1 (de) 2004-11-15

Family

ID=10847084

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00901259T ATE280757T1 (de) 1999-02-05 2000-01-31 Indolderivate und ihre verwendung als mcp-1 rezeptor antagonisten

Country Status (27)

Country Link
US (1) US6737435B1 (de)
EP (1) EP1150952B1 (de)
JP (1) JP2002536359A (de)
KR (1) KR20010094755A (de)
CN (1) CN1339025A (de)
AR (1) AR022461A1 (de)
AT (1) ATE280757T1 (de)
AU (1) AU770856B2 (de)
BR (1) BR0007984A (de)
CA (1) CA2356898A1 (de)
CZ (1) CZ20012807A3 (de)
DE (1) DE60015296T2 (de)
EE (1) EE200100403A (de)
GB (1) GB9902461D0 (de)
HU (1) HUP0105079A3 (de)
ID (1) ID30401A (de)
IL (1) IL144611A0 (de)
IS (1) IS5980A (de)
MY (1) MY133209A (de)
NO (1) NO20013809L (de)
NZ (1) NZ512680A (de)
PL (1) PL350184A1 (de)
RU (1) RU2235090C2 (de)
SK (1) SK11152001A3 (de)
TR (1) TR200102233T2 (de)
WO (1) WO2000046196A1 (de)
ZA (1) ZA200105311B (de)

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DK3461819T3 (da) 2017-09-29 2020-08-10 Probiodrug Ag Inhibitorer af glutaminylcyklase
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Also Published As

Publication number Publication date
ID30401A (id) 2001-11-29
IL144611A0 (en) 2002-05-23
SK11152001A3 (sk) 2001-12-03
CZ20012807A3 (cs) 2001-10-17
AR022461A1 (es) 2002-09-04
ZA200105311B (en) 2002-09-27
EP1150952A1 (de) 2001-11-07
JP2002536359A (ja) 2002-10-29
IS5980A (is) 2001-06-26
EP1150952B1 (de) 2004-10-27
TR200102233T2 (tr) 2001-12-21
AU2121300A (en) 2000-08-25
NO20013809L (no) 2001-10-02
NO20013809D0 (no) 2001-08-03
CN1339025A (zh) 2002-03-06
AU770856B2 (en) 2004-03-04
DE60015296D1 (de) 2004-12-02
KR20010094755A (ko) 2001-11-01
BR0007984A (pt) 2001-11-06
US6737435B1 (en) 2004-05-18
RU2235090C2 (ru) 2004-08-27
DE60015296T2 (de) 2006-02-02
GB9902461D0 (en) 1999-03-24
EE200100403A (et) 2002-10-15
HUP0105079A2 (hu) 2002-04-29
RU2001124567A (ru) 2004-01-10
WO2000046196A1 (en) 2000-08-10
MY133209A (en) 2007-10-31
NZ512680A (en) 2003-11-28
CA2356898A1 (en) 2000-08-10
PL350184A1 (en) 2002-11-18
HUP0105079A3 (en) 2002-11-28

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