EE05198B1 - Asendatud aminometlrhma sisaldavad N-(arlsulfonl)beetaaminohappe derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsi£onid - Google Patents
Asendatud aminometlrhma sisaldavad N-(arlsulfonl)beetaaminohappe derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsi£onidInfo
- Publication number
- EE05198B1 EE05198B1 EEP200300417A EEP200300417A EE05198B1 EE 05198 B1 EE05198 B1 EE 05198B1 EE P200300417 A EEP200300417 A EE P200300417A EE P200300417 A EEP200300417 A EE P200300417A EE 05198 B1 EE05198 B1 EE 05198B1
- Authority
- EE
- Estonia
- Prior art keywords
- arsulfone
- aminometric
- hrma
- beta
- preparation
- Prior art date
Links
- 150000001576 beta-amino acids Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
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- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
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- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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Applications Claiming Priority (2)
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FR0104315A FR2822827B1 (fr) | 2001-03-28 | 2001-03-28 | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
PCT/FR2002/001059 WO2002076964A1 (fr) | 2001-03-28 | 2002-03-27 | Derives de n-(arylsulfonyl)beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
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EE200300417A EE200300417A (et) | 2003-12-15 |
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EEP200300417A EE05198B1 (et) | 2001-03-28 | 2002-03-27 | Asendatud aminometlrhma sisaldavad N-(arlsulfonl)beetaaminohappe derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsi£onid |
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EP (1) | EP1373233B1 (sk) |
JP (1) | JP4188695B2 (sk) |
KR (1) | KR100887038B1 (sk) |
CN (1) | CN1297546C (sk) |
AR (1) | AR033686A1 (sk) |
AT (1) | ATE372329T1 (sk) |
AU (1) | AU2002255077B2 (sk) |
BG (1) | BG108201A (sk) |
BR (1) | BR0208489A (sk) |
CA (1) | CA2436225C (sk) |
CY (1) | CY1106980T1 (sk) |
CZ (1) | CZ301337B6 (sk) |
DE (1) | DE60222248T2 (sk) |
DK (1) | DK1373233T3 (sk) |
EA (1) | EA006430B1 (sk) |
EE (1) | EE05198B1 (sk) |
ES (1) | ES2291464T3 (sk) |
FR (1) | FR2822827B1 (sk) |
HK (1) | HK1059931A1 (sk) |
HR (1) | HRP20030748B1 (sk) |
HU (1) | HUP0401538A3 (sk) |
IL (3) | IL157215A0 (sk) |
IS (1) | IS2582B (sk) |
MA (1) | MA26995A1 (sk) |
ME (1) | MEP25408A (sk) |
MX (1) | MXPA03008756A (sk) |
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NZ (1) | NZ527429A (sk) |
PL (1) | PL207553B1 (sk) |
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SK (1) | SK286753B6 (sk) |
TN (1) | TNSN03058A1 (sk) |
TW (1) | TWI233923B (sk) |
UA (1) | UA75906C2 (sk) |
WO (1) | WO2002076964A1 (sk) |
ZA (1) | ZA200306037B (sk) |
Families Citing this family (37)
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CA2442476A1 (en) * | 2001-03-30 | 2002-10-10 | Pfizer Products Inc. | Pyridazinone aldose reductase inhibitors |
FR2840897B1 (fr) * | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
EP1631542A1 (en) | 2003-04-10 | 2006-03-08 | Amgen, Inc. | Bicyclic compounds having bradykinin receptors affinity and pharmaceutical compositions thereof |
WO2004099155A2 (en) * | 2003-05-02 | 2004-11-18 | Elan Pharmaceuticals, Inc. | 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (phenyl) amide derivates and related compounds as bradykinin b1 receptor antagonists for the treatment of inflamatory diseases |
ES2314418T3 (es) * | 2003-05-02 | 2009-03-16 | Elan Pharmaceuticals, Inc. | Derivados de amidas del acido 4-bromo-5-(2-clorobenzoilamino)-1h-pirazol-3-carboxicilico y compuestos relacionados como antagonistas del receptor b1 de bradiquinina para el tratamiento de enfermedades inflamatorias. |
WO2004098590A1 (en) * | 2003-05-02 | 2004-11-18 | Elan Pharmaceuticals, Inc. | 4-bromo-5- (2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (1-(aminocarbonyl) eth-1-yl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases |
AU2004265300A1 (en) * | 2003-08-07 | 2005-02-24 | Merck & Co., Inc. | Sulfonyl substituted N-(biarylmethyl) aminocyclopropanecarboxamides |
AU2004309357B2 (en) * | 2003-12-22 | 2010-10-07 | Merck Sharp & Dohme Corp. | Alpha-hydroxy amides as bradykinin antagonists or inverse agonists |
AU2005289881A1 (en) * | 2004-09-23 | 2006-04-06 | Amgen Inc. | Substituted sulfonamidopropionamides and methods of use |
WO2006041888A2 (en) * | 2004-10-06 | 2006-04-20 | Amgen Inc. | Substituted aryl or heteroarylsulfonylbutanamides for use as anti-inflammatory agents |
CA2583267A1 (en) | 2004-10-12 | 2006-04-27 | Amgen Inc. | Novel b1 bradykinin receptor antagonists |
WO2006044355A1 (en) | 2004-10-13 | 2006-04-27 | Amgen Inc. | Triazoles and their use as bradykinin b1 receptor antagonists |
US20060217362A1 (en) * | 2004-12-29 | 2006-09-28 | Tung Jay S | Novel compounds useful for bradykinin B1 receptor antagonism |
EP1741444A1 (en) * | 2005-07-05 | 2007-01-10 | Jerini AG | Kinin antagonists for treating bladder dysfunction |
ATE428702T1 (de) * | 2005-09-21 | 2009-05-15 | Reddy S Lab Eu Ltd Dr | Verfahren zur herstellung von aminosäurederivaten |
HU230518B1 (hu) | 2005-12-20 | 2016-10-28 | Richter Gedeon Nyrt. | Bradykinin B1 receptor szelektív antagonista hatással rendelkező új fenatridin származékok, eljárás előállításukra, és az ezeket tartalmazó gyógyszerkészítmények |
CA2666406A1 (en) | 2006-10-16 | 2008-04-24 | Gruenenthal Gmbh | Substituted sulfonamide derivatives for use as bradykinin 1 receptor modulators |
HUP0600810A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New sulfonamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600809A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them |
HUP0600808A3 (en) * | 2006-10-27 | 2008-09-29 | Richter Gedeon Nyrt | New benzamide derivatives as bradykinin antagonists, process for their preparation and pharmaceutical compositions containing them |
FR2916352B1 (fr) * | 2007-05-23 | 2009-07-31 | Sanofi Aventis Sa | Utilisation d'un antagoniste non peptidique du recepteur b1 de la bradykinine pour la preparation de medicaments utiles pour la prevention ou le traitement de l'hypertension arterielle. |
WO2008153967A1 (en) * | 2007-06-08 | 2008-12-18 | Contec Therapeutics, Inc. | Bk1 antagonist conjugates |
FR2919803B1 (fr) * | 2007-08-07 | 2011-07-22 | Sanofi Aventis | Utilisation d'un antagoniste non peptidique du recepteur b1 pour la preparation de medicaments utiles pour le traitement de l'obesite et des pathologies liees a l'obesite ou au diabete |
MX2010004431A (es) * | 2007-10-27 | 2010-05-13 | Richter Gedeon Nyrt | Nuevos derivados no peptidicos como antagonistas b1 de la bradiquinina. |
PE20091782A1 (es) * | 2008-04-08 | 2009-11-15 | Gruenenthal Chemie | Derivados de sulfonamida sustituida |
WO2010022300A1 (en) * | 2008-08-21 | 2010-02-25 | Forest Laboratories Holdings Limited | Methods for treating neuropathic pain |
WO2010022304A1 (en) * | 2008-08-21 | 2010-02-25 | Forest Laboratories Holdings Limited | Methods for treating cns disorders |
HUP1000598A2 (en) | 2010-11-05 | 2012-09-28 | Richter Gedeon Nyrt | Indole derivatives |
AR097279A1 (es) | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
JP6448498B2 (ja) * | 2015-08-04 | 2019-01-09 | 日本ゴア株式会社 | 回路基板製造プロセス液用精密フィルタ |
US11458142B2 (en) | 2017-08-25 | 2022-10-04 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compositions and methods for ameliorating pain |
BR112020005489A2 (pt) | 2017-09-22 | 2020-09-24 | Jubilant Epipad Llc, | composto da fórmula (i), composto de fórmula (ii), composto de fórmula (iii), processo de preparação de compostos de fórmula (i), processo de preparação de compostos de fórmula (ii), processo de preparação de compostos de fórmula (iii), composição farmacêutica, método para inibir uma ou mais famílias pad em uma célula, método para tratar uma afeção mediada por um ou mais pads, utilização do composto, método para o tratamento e/ou prevenção de uma afeção mediada por um ou mais distúrbios da família pad, método para o tratamento de artrite reumatoide e método de tratamento de câncer |
PT3697785T (pt) | 2017-10-18 | 2023-04-03 | Jubilant Epipad LLC | Compostos de imidazopiridina como inibidores de pad |
BR112020008851A2 (pt) | 2017-11-06 | 2020-10-20 | Jubilant Prodel LLC | composto da fórmula i, processo de preparação de compostos da fórmula i, composição farmacêutica, método para o tratamento e/ou prevenção de várias doenças, uso, método para o tratamento de câncer, método de tratamento de câncer e método para o tratamento e/ou prevenção de câncer e doenças infecciosas |
JP7368369B2 (ja) | 2017-11-24 | 2023-10-24 | ジュビラント・エピスクライブ・エルエルシー | Prmt5阻害剤としてのヘテロ環式化合物 |
WO2019175897A1 (en) | 2018-03-13 | 2019-09-19 | Jubilant Biosys Limited | Bicyclic compounds as inhibitors of pd1/pd-l1 interaction/activation |
CN114075274B (zh) * | 2022-01-18 | 2022-04-12 | 浙江湃肽生物有限公司深圳分公司 | 一种索玛鲁肽类似物及其制备方法和用途 |
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US5714497A (en) | 1993-02-15 | 1998-02-03 | Sanofi | Compounds bearing sulphamoyl and amidino radicals, their preparation process and pharmaceutical compositions containing them |
FR2701480B1 (fr) * | 1993-02-15 | 1995-05-24 | Sanofi Elf | Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
FR2735128B1 (fr) | 1995-06-07 | 1997-07-25 | Fournier Ind & Sante | Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique. |
DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
FR2743562B1 (fr) * | 1996-01-11 | 1998-04-03 | Sanofi Sa | Derives de n-(arylsulfonyl) aminoacides, leur preparation, les compositions pharmaceutiques en contenant |
CZ298814B6 (cs) * | 1996-01-23 | 2008-02-13 | Shionogi & Co., Ltd. | Sulfonované deriváty aminokyselin a metaloproteasové inhibitory obsahující tyto deriváty |
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- 2002-03-27 EA EA200300942A patent/EA006430B1/ru not_active IP Right Cessation
- 2002-03-27 KR KR1020037012554A patent/KR100887038B1/ko not_active IP Right Cessation
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2003
- 2003-08-03 IL IL157215A patent/IL157215A/en not_active IP Right Cessation
- 2003-08-07 IS IS6906A patent/IS2582B/is unknown
- 2003-08-13 MA MA27279A patent/MA26995A1/fr unknown
- 2003-09-17 HR HR20030748A patent/HRP20030748B1/xx not_active IP Right Cessation
- 2003-09-24 NO NO20034267A patent/NO326519B1/no not_active IP Right Cessation
- 2003-09-25 BG BG108201A patent/BG108201A/bg unknown
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2004
- 2004-04-19 HK HK04102735A patent/HK1059931A1/xx not_active IP Right Cessation
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2007
- 2007-11-07 CY CY20071101426T patent/CY1106980T1/el unknown
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2008
- 2008-06-16 IL IL192233A patent/IL192233A/en not_active IP Right Cessation
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