EE04047B1 - Sidovudiini, 1592U89 ja 3TC või FTC sünergistlikud kombinatsioonid - Google Patents

Sidovudiini, 1592U89 ja 3TC või FTC sünergistlikud kombinatsioonid

Info

Publication number
EE04047B1
EE04047B1 EE9700240A EE9700240A EE04047B1 EE 04047 B1 EE04047 B1 EE 04047B1 EE 9700240 A EE9700240 A EE 9700240A EE 9700240 A EE9700240 A EE 9700240A EE 04047 B1 EE04047 B1 EE 04047B1
Authority
EE
Estonia
Prior art keywords
ftc
zidovudine
synergistic combinations
synergistic
combinations
Prior art date
Application number
EE9700240A
Other languages
English (en)
Estonian (et)
Other versions
EE9700240A (et
Inventor
Walter Barry David
Heider St. Clair Martha
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26306774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04047(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9506490.3A external-priority patent/GB9506490D0/en
Priority claimed from GBGB9506489.5A external-priority patent/GB9506489D0/en
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of EE9700240A publication Critical patent/EE9700240A/xx
Publication of EE04047B1 publication Critical patent/EE04047B1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
EE9700240A 1995-03-30 1996-03-28 Sidovudiini, 1592U89 ja 3TC või FTC sünergistlikud kombinatsioonid EE04047B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506490.3A GB9506490D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
GBGB9506489.5A GB9506489D0 (en) 1995-03-30 1995-03-30 Antiviral combinations
PCT/EP1996/001352 WO1996030025A1 (en) 1995-03-30 1996-03-28 Synergistic combinations of zidovudine, 1592u89 and 3tc or ftc

Publications (2)

Publication Number Publication Date
EE9700240A EE9700240A (et) 1998-04-15
EE04047B1 true EE04047B1 (et) 2003-06-16

Family

ID=26306774

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700240A EE04047B1 (et) 1995-03-30 1996-03-28 Sidovudiini, 1592U89 ja 3TC või FTC sünergistlikud kombinatsioonid

Country Status (35)

Country Link
US (1) US6417191B1 (cs)
EP (1) EP0817637B1 (cs)
JP (1) JP2954357B2 (cs)
KR (1) KR100542536B1 (cs)
CN (1) CN1103593C (cs)
AP (1) AP652A (cs)
AT (1) ATE220551T1 (cs)
AU (1) AU715213B2 (cs)
BR (3) BRPI9607851B8 (cs)
CA (1) CA2216634C (cs)
CZ (1) CZ295940B6 (cs)
DE (3) DE122005000029I1 (cs)
DK (1) DK0817637T3 (cs)
EA (1) EA000626B3 (cs)
EE (1) EE04047B1 (cs)
ES (1) ES2179193T3 (cs)
FR (1) FR05C0022I2 (cs)
GE (1) GEP20022647B (cs)
HU (1) HU224010B1 (cs)
IL (1) IL117727A (cs)
LU (1) LU91171I2 (cs)
MX (1) MX9707316A (cs)
MY (1) MY115461A (cs)
NL (1) NL300195I2 (cs)
NO (2) NO313787B1 (cs)
NZ (1) NZ306419A (cs)
OA (1) OA10616A (cs)
PL (1) PL187085B1 (cs)
PT (1) PT817637E (cs)
RO (1) RO117995B1 (cs)
SI (1) SI0817637T1 (cs)
SK (1) SK283825B6 (cs)
TR (1) TR199701074T1 (cs)
UA (1) UA60293C2 (cs)
WO (1) WO1996030025A1 (cs)

Families Citing this family (32)

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PL330747A1 (en) 1996-06-25 1999-05-24 Glaxo Group Ltd Vx478, zidovudin, ftc and/or 3tc containing combinations for use in treating hiv infections
US6113920A (en) * 1996-10-31 2000-09-05 Glaxo Wellcome Inc. Pharmaceutical compositions
TW536403B (en) * 1997-03-24 2003-06-11 Glaxo Group Ltd An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy
AR012702A1 (es) * 1997-05-17 2000-11-08 Glaxo Group Ltd Combinacion de (-)-(1s,4r)-4-[2-amino-6-(ciclopropilamino)-9h-purin-9-il]- 2-ciclopenteno-1-metanol y un inhibidor dee transcriptasa reversa no nucleosidouna formulacion farmaceutica que comprende la combinacion, su uso medico en terapia para tratar la infeccion de vih, y un empaque para el paciente
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt
AU769660B2 (en) * 1997-05-17 2004-01-29 Glaxo Group Limited Carbocyclic nucleoside hemisulfate and its use in treating viral infections
GB9809213D0 (en) * 1998-04-29 1998-07-01 Glaxo Group Ltd Pharmaceutical compositions
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
GB9820417D0 (en) * 1998-09-18 1998-11-11 Glaxo Group Ltd Antiviral combinations
US6432966B2 (en) 1999-10-29 2002-08-13 Smithkline Beecham Corporation Antiviral combinations
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
AP2220A (en) * 2001-05-11 2011-03-24 Cipla Medpro Pty Ltd Pharmaceutical composition.
AR040242A1 (es) * 2002-06-04 2005-03-23 Glaxo Group Ltd Composiciones farmaceuticas
EP1585527A1 (en) 2003-01-14 2005-10-19 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
AU2004224191A1 (en) 2003-03-24 2004-10-07 F. Hoffmann-La Roche Ag Non-nucleoside reverse transcriptase inhibitors
EP2270511A3 (en) 2003-10-24 2011-08-24 Immunaid Pty Ltd Method of therapy
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
AU2006303368B2 (en) 2005-10-19 2011-05-26 F. Hoffmann-La Roche Ag Non-Nucleoside Reverse Transcriptase Inhibitors
JP5415957B2 (ja) 2006-12-13 2014-02-12 エフ.ホフマン−ラ ロシュ アーゲー 非ヌクレオシド逆転写酵素阻害剤としての2−(ピペリジン−4−イル)−4−フェノキシ−又はフェニルアミノ−ピリミジン誘導体
JP5467870B2 (ja) * 2007-02-09 2014-04-09 アルファファーム ピーティーワイ リミテッド 異なる物理的形態の2種以上の有効医薬成分を含有する投薬形態
ES2548508T3 (es) 2009-05-27 2015-10-19 Biotempus Limited Métodos de tratamiento de enfermedades
DK2531027T3 (en) 2010-01-27 2015-07-20 Viiv Healthcare Co A therapeutic combination comprising dolutegravir, abacavir and lamivudine,
HK1220390A1 (zh) 2013-08-29 2017-05-05 Teva Pharmaceutical Industries Ltd. 包括恩曲他滨,替诺福韦,达芦那韦和利托那韦的单位剂型以及包含达芦那韦和利托那韦的单体片剂
WO2015155673A1 (en) 2014-04-08 2015-10-15 Teva Pharmaceutical Industries Ltd Unit dosage form comprising emtricitabine, tenofovir, darunavir and ritonavir
CN117088931A (zh) 2014-08-12 2023-11-21 莫纳什大学 定向淋巴的前药
CN108137482B (zh) 2015-09-08 2024-03-15 莫纳什大学 定向淋巴的前药
EP4306524A3 (en) 2017-08-29 2024-09-11 PureTech LYT, Inc. Lymphatic system-directing lipid prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US11304954B2 (en) 2017-12-19 2022-04-19 Puretech Lyt, Inc. Lipid prodrugs of mycophenolic acid and uses thereof
US11608345B1 (en) 2017-12-19 2023-03-21 Puretech Lyt, Inc. Lipid prodrugs of rapamycin and its analogs and uses thereof
US20210268115A1 (en) 2020-02-05 2021-09-02 Puretech Lyt, Inc. Lipid prodrugs of neurosteroids

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5047407A (en) 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
US5122517A (en) 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
GB9009861D0 (en) 1990-05-02 1990-06-27 Glaxo Group Ltd Chemical compounds
GB9104740D0 (en) 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
ATE131730T1 (de) * 1991-05-16 1996-01-15 Glaxo Group Ltd Nukleosidanalogen enthaltende antiviren- zubereitungen
ES2138624T3 (es) * 1992-05-13 2000-01-16 Wellcome Found Combinaciones terapeuticas.
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
GB9417249D0 (en) 1994-08-26 1994-10-19 Wellcome Found A novel salt
US5869461A (en) 1995-03-16 1999-02-09 Yale University Reducing toxicity of L-nucleosides with D-nucleosides
ATE230267T1 (de) 1996-06-25 2003-01-15 Glaxo Group Ltd Zusammensetzungen enthaltend vx478, zidovudine und 159u89 für die verwendung in der behandlung von hiv
PL330747A1 (en) 1996-06-25 1999-05-24 Glaxo Group Ltd Vx478, zidovudin, ftc and/or 3tc containing combinations for use in treating hiv infections
DE10226522A1 (de) * 2002-06-14 2003-12-24 Degussa Verwendung von Übergangsmetallkomplexen mit stickstoffhaltigen mehrzähnigen Liganden als Bleichkatalysator und Bleichmittelzusammensetzung

Also Published As

Publication number Publication date
KR19980703420A (ko) 1998-11-05
CA2216634A1 (en) 1996-10-03
AU715213B2 (en) 2000-01-20
ATE220551T1 (de) 2002-08-15
NZ306419A (en) 2000-01-28
PT817637E (pt) 2002-11-29
CZ295940B6 (cs) 2005-12-14
HU224010B1 (hu) 2005-04-28
GEP20022647B (en) 2002-03-25
PL187085B1 (pl) 2004-05-31
DE122005000029I1 (de) 2005-10-06
CA2216634C (en) 2004-07-20
FR05C0022I1 (cs) 2005-06-10
DE122005000029I2 (de) 2006-04-27
AP652A (en) 1998-06-19
SK283825B6 (sk) 2004-02-03
NO2005014I2 (no) 2008-02-11
EP0817637B1 (en) 2002-07-17
EP0817637A1 (en) 1998-01-14
OA10616A (en) 2001-03-15
IL117727A (en) 1999-11-30
EE9700240A (et) 1998-04-15
EA000626B3 (ru) 2016-04-29
EA000626B1 (ru) 1999-12-29
BR9607851A (pt) 1998-07-21
NO313787B1 (no) 2002-12-02
FR05C0022I2 (cs) 2005-10-21
NL300195I2 (nl) 2005-11-01
RO117995B1 (ro) 2002-12-30
NO2005014I1 (no) 2005-06-06
SI0817637T1 (en) 2002-10-31
HUP9801571A2 (hu) 1999-01-28
DE69622386T2 (de) 2003-02-13
UA60293C2 (uk) 2003-10-15
CN1185110A (zh) 1998-06-17
HK1009401A1 (en) 1999-09-10
HUP9801571A3 (en) 2001-04-28
NO974510D0 (no) 1997-09-29
DE69622386D1 (de) 2002-08-22
LU91171I9 (cs) 2018-12-28
MX9707316A (es) 1997-11-29
KR100542536B1 (ko) 2006-03-23
BRPI9607851B8 (pt) 2019-11-05
BRPI9612992B1 (pt) 2020-08-04
AU5497296A (en) 1996-10-16
PL322532A1 (en) 1998-02-02
JPH10511682A (ja) 1998-11-10
SK129597A3 (en) 1998-07-08
ES2179193T3 (es) 2003-01-16
EA199700203A1 (ru) 1998-02-26
DK0817637T3 (da) 2002-11-11
WO1996030025A1 (en) 1996-10-03
NL300195I1 (nl) 2005-08-01
TR199701074T1 (xx) 1998-02-21
CN1103593C (zh) 2003-03-26
NO974510L (no) 1997-09-29
US6417191B1 (en) 2002-07-09
CZ309097A3 (cs) 1998-05-13
BR9607851B1 (pt) 2009-01-13
AP9701089A0 (en) 1997-10-31
IL117727A0 (en) 1996-07-23
LU91171I2 (fr) 2005-07-04
MY115461A (en) 2003-06-30
JP2954357B2 (ja) 1999-09-27

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