EE03687B1 - Furaandiarüülmetülideeni derivaadid, nende valmistamise meetod ja kasutamine teraapias - Google Patents
Furaandiarüülmetülideeni derivaadid, nende valmistamise meetod ja kasutamine teraapiasInfo
- Publication number
- EE03687B1 EE03687B1 EE9800333A EE9800333A EE03687B1 EE 03687 B1 EE03687 B1 EE 03687B1 EE 9800333 A EE9800333 A EE 9800333A EE 9800333 A EE9800333 A EE 9800333A EE 03687 B1 EE03687 B1 EE 03687B1
- Authority
- EE
- Estonia
- Prior art keywords
- furandiarylmethylidene
- therapy
- derivatives
- preparation
- furandiarylmethylidene derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Rheumatology (AREA)
- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9604236A FR2747123B1 (fr) | 1996-04-04 | 1996-04-04 | Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique |
FR9607922A FR2747124B1 (fr) | 1996-04-04 | 1996-06-26 | Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique |
PCT/FR1997/000602 WO1997037984A1 (fr) | 1996-04-04 | 1997-04-03 | Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
EE9800333A EE9800333A (et) | 1999-04-15 |
EE03687B1 true EE03687B1 (et) | 2002-04-15 |
Family
ID=9490907
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EE9800333A EE03687B1 (et) | 1996-04-04 | 1997-04-03 | Furaandiarüülmetülideeni derivaadid, nende valmistamise meetod ja kasutamine teraapias |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0891345B1 (et) |
JP (1) | JP2000508638A (et) |
KR (1) | KR20000005146A (et) |
CN (1) | CN1215396A (et) |
AR (1) | AR006539A1 (et) |
AT (1) | ATE204268T1 (et) |
AU (1) | AU717146B2 (et) |
BG (1) | BG62808B1 (et) |
BR (1) | BR9708510A (et) |
CA (1) | CA2248949A1 (et) |
CZ (1) | CZ318898A3 (et) |
DE (1) | DE69706157T2 (et) |
DK (1) | DK0891345T3 (et) |
EE (1) | EE03687B1 (et) |
ES (1) | ES2162678T3 (et) |
FR (2) | FR2747123B1 (et) |
GE (1) | GEP20032924B (et) |
IL (1) | IL126105A (et) |
NO (1) | NO984624L (et) |
NZ (1) | NZ331672A (et) |
PL (1) | PL329213A1 (et) |
PT (1) | PT891345E (et) |
RU (1) | RU2189979C2 (et) |
SI (1) | SI0891345T1 (et) |
SK (1) | SK283292B6 (et) |
TW (1) | TW353660B (et) |
WO (1) | WO1997037984A1 (et) |
ZA (1) | ZA972894B (et) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6180651B1 (en) * | 1996-04-04 | 2001-01-30 | Bristol-Myers Squibb | Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics |
CA2285567A1 (en) * | 1997-04-02 | 1998-10-08 | Merck Frosst Canada & Co. | Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors |
FR2775477B1 (fr) * | 1998-02-27 | 2000-05-19 | Union Pharma Scient Appl | Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique |
CN1106392C (zh) * | 2000-10-24 | 2003-04-23 | 中国科学院上海有机化学研究所 | 一种β位不含取代基的丁烯酸内酯及其合成的方法 |
US7323495B2 (en) * | 2002-11-05 | 2008-01-29 | Magnachem International Laboratories, Inc. | Synthetic lactone formulations and method of use |
CN100569747C (zh) * | 2003-03-31 | 2009-12-16 | 科学与工业研究会 | 巯基-苯基-萘基-甲烷衍生物及其制备 |
ATE342722T1 (de) | 2003-05-07 | 2006-11-15 | Osteologix As | Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen |
US8779168B2 (en) * | 2010-12-16 | 2014-07-15 | Transitions Optical, Inc. | Lactone compounds and materials made therefrom |
WO2022195579A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6027694A (en) * | 1993-01-15 | 1994-08-15 | G.D. Searle & Co. | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
US5585504A (en) * | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
-
1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/fr not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/fr not_active Expired - Lifetime
-
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/zh active
- 1997-04-03 CA CA002248949A patent/CA2248949A1/fr not_active Abandoned
- 1997-04-03 DE DE69706157T patent/DE69706157T2/de not_active Expired - Lifetime
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/cs unknown
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/fr not_active Application Discontinuation
- 1997-04-03 AT AT97919476T patent/ATE204268T1/de active
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 EE EE9800333A patent/EE03687B1/et unknown
- 1997-04-03 SI SI9730222T patent/SI0891345T1/xx unknown
- 1997-04-03 PL PL97329213A patent/PL329213A1/xx unknown
- 1997-04-03 BR BR9708510A patent/BR9708510A/pt not_active IP Right Cessation
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/ru not_active IP Right Cessation
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/ko not_active Application Discontinuation
- 1997-04-03 IL IL12610597A patent/IL126105A/xx not_active IP Right Cessation
- 1997-04-03 CN CN97193543A patent/CN1215396A/zh active Pending
- 1997-04-03 EP EP97919476A patent/EP0891345B1/fr not_active Expired - Lifetime
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 SK SK1375-98A patent/SK283292B6/sk not_active IP Right Cessation
- 1997-04-03 PT PT97919476T patent/PT891345E/pt unknown
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 ES ES97919476T patent/ES2162678T3/es not_active Expired - Lifetime
- 1997-04-03 JP JP9535910A patent/JP2000508638A/ja active Pending
- 1997-04-03 DK DK97919476T patent/DK0891345T3/da active
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/xx unknown
- 1997-04-04 AR ARP970101359A patent/AR006539A1/es not_active Application Discontinuation
-
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/bg unknown
- 1998-10-02 NO NO984624A patent/NO984624L/no not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
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KB4A | Valid patent at the end of a year |
Effective date: 20021231 |
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KB4A | Valid patent at the end of a year |
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KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20091231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20101231 |