EE03473B1 - Prootonpumba inhibiitorit sisaldav farmatseutiline kompositsioon - Google Patents

Prootonpumba inhibiitorit sisaldav farmatseutiline kompositsioon

Info

Publication number
EE03473B1
EE03473B1 EE9700244A EE9700244A EE03473B1 EE 03473 B1 EE03473 B1 EE 03473B1 EE 9700244 A EE9700244 A EE 9700244A EE 9700244 A EE9700244 A EE 9700244A EE 03473 B1 EE03473 B1 EE 03473B1
Authority
EE
Estonia
Prior art keywords
proton pump
pump inhibitor
pharmaceutical composition
composition
ppi
Prior art date
Application number
EE9700244A
Other languages
English (en)
Estonian (et)
Other versions
EE9700244A (et
Inventor
J. Dave Kaushik
B. Williams James
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of EE9700244A publication Critical patent/EE9700244A/xx
Publication of EE03473B1 publication Critical patent/EE03473B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
EE9700244A 1995-04-04 1996-03-29 Prootonpumba inhibiitorit sisaldav farmatseutiline kompositsioon EE03473B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/416,275 US5708017A (en) 1995-04-04 1995-04-04 Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
PCT/US1996/004355 WO1996031213A1 (en) 1995-04-04 1996-03-29 Pharmaceutical composition containing proton pump inhibitors

Publications (2)

Publication Number Publication Date
EE9700244A EE9700244A (et) 1998-04-15
EE03473B1 true EE03473B1 (et) 2001-08-15

Family

ID=23649308

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700244A EE03473B1 (et) 1995-04-04 1996-03-29 Prootonpumba inhibiitorit sisaldav farmatseutiline kompositsioon

Country Status (30)

Country Link
US (1) US5708017A (uk)
EP (1) EP0819004B1 (uk)
JP (1) JP4603631B2 (uk)
KR (1) KR100419105B1 (uk)
CN (1) CN1080119C (uk)
AT (1) ATE438380T1 (uk)
AU (1) AU703755B2 (uk)
BR (1) BR9604803A (uk)
CA (1) CA2217515C (uk)
CY (1) CY2613B2 (uk)
CZ (1) CZ287297B6 (uk)
DE (1) DE69637985D1 (uk)
DK (1) DK0819004T3 (uk)
EA (1) EA000087B1 (uk)
EE (1) EE03473B1 (uk)
ES (1) ES2329098T3 (uk)
HK (1) HK1004658A1 (uk)
HU (1) HU227864B1 (uk)
IS (1) IS2706B (uk)
MX (1) MX9707694A (uk)
NO (1) NO312994B1 (uk)
NZ (1) NZ305708A (uk)
PL (1) PL183144B1 (uk)
PT (1) PT819004E (uk)
SI (1) SI0819004T1 (uk)
SK (1) SK282872B6 (uk)
TR (1) TR199701117T1 (uk)
UA (1) UA42061C2 (uk)
WO (1) WO1996031213A1 (uk)
ZA (1) ZA962657B (uk)

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CA2298823C (en) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Stabilized composition comprising a benzimidazole type compound
ATE231857T1 (de) * 1998-08-10 2003-02-15 Winston Pharmateuticals Llc Prodrugs für proton-pump-inhibitoren
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
WO2000020016A1 (en) * 1998-10-06 2000-04-13 Mars U.K. Limited Animal stereotypy
PT1156806E (pt) * 1999-02-23 2004-07-30 Merck & Co Inc Composicao farmaceutica contendo inibidores da bomba de protoes
FR2793688B1 (fr) 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
JP4081273B2 (ja) 1999-10-20 2008-04-23 エーザイ・アール・アンド・ディー・マネジメント株式会社 ベンズイミダゾール系化合物安定化方法
GB2358136A (en) * 2000-01-15 2001-07-18 Univ Montfort A medicament for the treatment of equine oral stereotypies using a pH regulator
US6787342B2 (en) * 2000-02-16 2004-09-07 Merial Limited Paste formulations
DK1286669T3 (da) 2000-05-30 2010-08-09 Merial Ltd Præparater til forebyggelse af mavesår hos heste
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
US20020064555A1 (en) * 2000-09-29 2002-05-30 Dan Cullen Proton pump inhibitor formulation
AU2001211213A1 (en) * 2000-10-20 2002-04-29 Galephar M/F Stable oral formulation containing benzimidazole derivative
MXPA03003511A (es) * 2000-10-27 2004-05-04 Leo Pharma As Composicion topica que contiene al menos una vitamina d o un analogo de vitamina de y al menos un corticosteroide.
CN100536844C (zh) * 2000-12-07 2009-09-09 尼科梅德有限责任公司 包含酸不稳定活性成分的糊剂形式的药物制剂
US7357943B2 (en) * 2000-12-07 2008-04-15 Nycomed Gmbh Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient
GB2398221B (en) * 2001-10-26 2006-04-12 John Kohnke Dosage system & dosage vehicle therefor
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US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
WO2004004690A1 (en) * 2002-07-03 2004-01-15 Abbott Laboratories Liquid dosage forms of proton pump inhibitors
CA2492718C (en) * 2002-07-19 2010-12-21 Michael E. Garst Prodrugs of proton pump inhibitors
GB2394895A (en) * 2002-11-06 2004-05-12 Cipla Ltd Proton pump inhibitor composition in paste form
WO2004064719A2 (en) * 2003-01-24 2004-08-05 State Of Israel, Ministry Of Agriculture Synergistic compositions and methods for potentiating anti-oxidative activity
WO2005000269A1 (en) * 2003-06-26 2005-01-06 Cipla Limited Pharmaceutical formulations comprising a proton pump inhibitor
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005039640A1 (en) * 2003-10-03 2005-05-06 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump inhibitor prodrugs
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
US20070161679A1 (en) * 2004-02-18 2007-07-12 Allergan, Inc. Method and compositions for the intravenous administration of compounds related to proton pump inhibitors
BRPI0507784A (pt) * 2004-02-18 2007-07-17 Allergan Inc métodos e composições para a administração de pró-fármacos de inibidores da bomba de prótons
WO2005097083A2 (en) * 2004-03-30 2005-10-20 Dermatrends,Inc. Transdermal administration of proton pump inhibitors
EP1742630A4 (en) * 2004-04-16 2010-01-20 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND PROKINETIC AGENT
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
WO2006026829A1 (en) * 2004-09-09 2006-03-16 Metelli Pty Ltd Stable paste composition of enteric coated acid labile active agent and use thereof
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
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CA2716367C (en) 2008-02-20 2015-05-26 The Curators Of The University Of Missouri Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same
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Also Published As

Publication number Publication date
AU703755B2 (en) 1999-04-01
SK135097A3 (en) 1998-06-03
MX9707694A (es) 1997-12-31
JPH11503160A (ja) 1999-03-23
CA2217515C (en) 2005-03-15
UA42061C2 (uk) 2001-10-15
TR199701117T1 (xx) 1998-02-21
NO974589L (no) 1997-12-03
HUP9801626A3 (en) 2000-06-28
KR100419105B1 (ko) 2004-05-31
CA2217515A1 (en) 1996-10-10
KR19980703576A (ko) 1998-11-05
CZ287297B6 (en) 2000-10-11
WO1996031213A1 (en) 1996-10-10
EA199700294A1 (ru) 1998-02-26
PL183144B1 (pl) 2002-05-31
BR9604803A (pt) 1998-06-09
ATE438380T1 (de) 2009-08-15
EP0819004A1 (en) 1998-01-21
CY2613B2 (en) 2011-04-06
US5708017A (en) 1998-01-13
DE69637985D1 (de) 2009-09-17
NO974589D0 (no) 1997-10-03
AU5379796A (en) 1996-10-23
NZ305708A (en) 1999-11-29
IS2706B (is) 2011-01-15
ES2329098T3 (es) 2009-11-20
IS4576A (is) 1997-10-02
CN1080119C (zh) 2002-03-06
HK1004658A1 (en) 1998-12-04
CZ313597A3 (cs) 1998-04-15
SI0819004T1 (sl) 2009-12-31
ZA962657B (en) 1996-10-09
JP4603631B2 (ja) 2010-12-22
SK282872B6 (sk) 2003-01-09
PL322619A1 (en) 1998-02-02
EP0819004A4 (en) 2006-01-18
HU227864B1 (en) 2012-05-29
DK0819004T3 (da) 2009-11-30
EE9700244A (et) 1998-04-15
NO312994B1 (no) 2002-07-29
EA000087B1 (ru) 1998-06-25
CN1185107A (zh) 1998-06-17
EP0819004B1 (en) 2009-08-05
PT819004E (pt) 2009-10-12
HUP9801626A2 (hu) 1999-02-01

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