ECSP12011981A - Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación - Google Patents

Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación

Info

Publication number
ECSP12011981A
ECSP12011981A ECSP12011981A ECSP12011981A EC SP12011981 A ECSP12011981 A EC SP12011981A EC SP12011981 A ECSP12011981 A EC SP12011981A EC SP12011981 A ECSP12011981 A EC SP12011981A
Authority
EC
Ecuador
Prior art keywords
coagulation
flat surfaces
response
portable device
evaluation method
Prior art date
Application number
Other languages
English (en)
Inventor
Robert Glenn Dennis
Thomas H Fischer
Joseph A Dacorta
Original Assignee
Entegrion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entegrion Inc filed Critical Entegrion Inc
Publication of ECSP12011981A publication Critical patent/ECSP12011981A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/006—Determining flow properties indirectly by measuring other parameters of the system
    • G01N2011/008—Determining flow properties indirectly by measuring other parameters of the system optical properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Se describe un dispositivo, sistema y método en el cual muestras de sangre de volumen pequeño se someten a fuerzas de cizalladura y esfuerzos de cizalladura entre dos superficies planas paralelas a las cuales se imparten trayectorias de movimiento lineales. La formación de coágulos o la coagulación de la muestra se miden a partir del acoplamiento mecánico dinámico que ocurre entre las dos superficies planas paralelas. La detección de la respuesta de coagulación puede realizarse por sondeo óptico o por medida de los efectos físicos de la muestra de sangre que se fija a las superficies planas, y restricción del movimiento de las mismas.
ECSP12011981 2009-12-18 2012-06-18 Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación ECSP12011981A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28778009P 2009-12-18 2009-12-18
PCT/US2010/060911 WO2011075614A2 (en) 2009-12-18 2010-12-17 Portable coagulation monitoring device and method of assessing coagulation response

Publications (1)

Publication Number Publication Date
ECSP12011981A true ECSP12011981A (es) 2012-08-31

Family

ID=44151642

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12011981 ECSP12011981A (es) 2009-12-18 2012-06-18 Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación

Country Status (16)

Country Link
US (2) US8450078B2 (es)
EP (1) EP2513647B1 (es)
JP (1) JP5655091B2 (es)
CN (1) CN102687009B (es)
AU (1) AU2010330861B2 (es)
BR (1) BR112012014421B8 (es)
CA (1) CA2780492C (es)
CO (1) CO6551732A2 (es)
CR (1) CR20120326A (es)
EC (1) ECSP12011981A (es)
ES (1) ES2543099T3 (es)
HN (1) HN2012001269A (es)
MX (1) MX2012007084A (es)
NI (1) NI201200109A (es)
PE (1) PE20121723A1 (es)
WO (1) WO2011075614A2 (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7892188B2 (en) 2003-10-22 2011-02-22 Hemosonics, Llc Method and apparatus for characterization of clot formation
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
BRPI1006722A2 (pt) 2009-04-09 2017-10-10 Entegrion Inc "método de preparação de hemoderivados desidratado, hemoderivados desidratados, bandagem ou auxílio cirúrgico, método para a preparação de plaquetas sanguíneas fixas desidratadas, plaquetas sanguíneas fixas desidratadas, método para o tratamento de um paciente que sofre de um distúrbio sanguíneo e plaquetas de sangue fixas secas por atomização tendo geometria com cavidades esféricas"
US20110142885A1 (en) 2009-09-16 2011-06-16 Velico Medical, Inc. Spray-dried human plasma
US12405280B2 (en) 2009-12-18 2025-09-02 Entegrion, Inc. Portable coagulation monitoring devices, systems, and methods
US10739358B2 (en) 2009-12-18 2020-08-11 Entegrion, Inc. Portable coagulation monitoring devices, systems, and methods
DK2555704T3 (da) 2010-04-08 2019-08-05 Hemosonics Llc Visning af hæmostatiske parametre
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
CA2826770C (en) 2011-02-15 2020-06-23 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
DK2676136T3 (da) 2011-02-15 2021-03-15 Hemosonics Llc Indretninger, systemer og fremgangsmåder til vurdering af hæmostase
WO2012159021A2 (en) 2011-05-19 2012-11-22 Hemosonics, Llc Portable hemostasis analyzer
WO2013099238A1 (ja) * 2011-12-26 2013-07-04 パナソニック株式会社 液体試料測定システム及び測定装置
JP2015503767A (ja) 2012-01-16 2015-02-02 エイブラム サイエンティフィック，インコーポレーテッド 流体の物理的特性を測定するための方法、デバイス、およびシステム
WO2014085804A1 (en) 2012-11-30 2014-06-05 The University Of North Carolina At Chapel Hill Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care diagnostic device
EP2932250B1 (en) 2012-12-17 2017-10-04 Abbott Point Of Care, Inc. Self correction for spatial orientation and motion of portable clinical testing devices
CN105008920B (zh) 2012-12-17 2019-03-29 雅培医护站股份有限公司 便携式临床分析系统中的空间方位确定
WO2014099421A1 (en) 2012-12-17 2014-06-26 Abbott Point Of Care Inc Operation and verification of a portable clinical analysis system
WO2014099419A1 (en) 2012-12-17 2014-06-26 Abbott Point Of Care Inc A portable clinical analysis system for hematocrit measurement
WO2014099420A1 (en) 2012-12-17 2014-06-26 Abbott Point Of Care Inc A portable clinical analysis system for immunometric measurement
KR101481240B1 (ko) * 2012-12-27 2015-01-19 고려대학교 산학협력단 마이크로 유동칩 기반 혈소판 기능 및 약물반응 검사 장치 및 방법
CN103487377B (zh) * 2013-10-11 2016-03-09 江苏英诺华医疗技术有限公司 一种全血凝血功能检测仪及检测方法
US10823743B1 (en) * 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
EP3069135B1 (en) * 2013-11-15 2024-10-30 Entegrion, Inc. Coagulation monitoring method and test cartridge
US9452199B2 (en) * 2014-01-17 2016-09-27 General Electric Company Platelet activation and growth factor release using electric pulses
US9354243B2 (en) 2014-05-05 2016-05-31 Haemonetics Corporation Methodologies and reagents for detecting fibrinolysis and hyperfibrinolysis in a blood sample using viscoelastic analysis
HRP20230171T1 (hr) * 2014-09-09 2023-03-31 Perosphere Technologies Inc. Univerzalni test koagulacije na bazi mikrofluidnog čipa
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
EP3218723B1 (en) * 2014-11-14 2021-10-06 Haemonetics Corporation Apparatus and method to determine stroke subtype
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
CN105403691B (zh) * 2016-01-01 2017-08-18 赛奥生物科技（青岛）有限公司 一种血液试剂分析系统
CN106198943B (zh) * 2016-08-16 2019-11-12 中国科学院苏州生物医学工程技术研究所 一种血液动力学分析装置
GB2555870A (en) 2016-11-15 2018-05-16 Haemair Ltd Rheometer and method for the use thereof
EP3541443B1 (en) * 2016-11-17 2024-04-10 enicor GmbH Coated articles for blood coagulation testing and methods of preparing the same
JP7432500B2 (ja) 2017-04-20 2024-02-16 ヘモソニックス エル・エル・シー 止血機能の分析のための使い捨てシステム
EP3830573B1 (en) * 2018-07-29 2024-10-16 KOC Universitesi Microfluidic thromboelastometry instrument
US12019041B2 (en) 2018-11-20 2024-06-25 Xatek, Inc. Portable dielectric spectroscopy device
CN113412420A (zh) 2019-02-04 2021-09-17 仪宝科技公司 流体性质测量装置和方法
EP4097471A4 (en) 2020-01-29 2024-07-03 Ifirst Medical Technologies, Inc. Medical analyzer and diagnostic sample profiler
US20210260589A1 (en) * 2020-02-26 2021-08-26 Emmanuel Mpock Method and Apparatus for Measuring Blood Coagulation
KR102414376B1 (ko) * 2020-05-26 2022-06-29 고려대학교 산학협력단 지혈 검사 장치
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US12539355B2 (en) 2022-09-15 2026-02-03 Velico Medical, Inc. Dryer for a spray drying system
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
WO2024059770A1 (en) 2022-09-15 2024-03-21 Velico Medical, Inc. Rapid spray drying system
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
US12571587B2 (en) 2022-09-15 2026-03-10 Velico Medical, Inc. Finishing apparatus for a spray drying system
CN117783546A (zh) * 2023-11-22 2024-03-29 苏州科技大学 一种基于激光的床边血型检测装置及其检测方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023A (en) * 1847-03-20 Stocking-loom
JPH0743388B2 (ja) * 1990-05-29 1995-05-15 日立化成工業株式会社 血液凝固に伴うゲル化反応の測定法，測定装置及び測定用素子
FR2664982B1 (fr) * 1990-07-20 1994-04-29 Serbio Appareil de detection de changement de viscosite, par mesure d'un glissement relatif, en particulier pour la detection du temps de coagulation du sang.
US5838515A (en) * 1996-04-30 1998-11-17 Quantum Corporation PWM/linear driver for disk drive voice coil actuator
US6046051A (en) * 1997-06-27 2000-04-04 Hemosense, Inc. Method and device for measuring blood coagulation or lysis by viscosity changes
KR20020065519A (ko) * 1999-11-15 2002-08-13 아이-스탯 코오포레이션 유체 샘플 중의 응고물을 분석하기 위한 장치 및 방법
US6750053B1 (en) * 1999-11-15 2004-06-15 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
US6743596B1 (en) * 2000-10-27 2004-06-01 Biomerieux, Inc. Method of determining global coagulability hemostatic potential
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
ES2234349B1 (es) * 2002-04-18 2006-11-01 Servicio De Instrumentacion Hospitalaria, S.L. Dispositivo de medicion de tiempo de coagulacion y actividad plaquetaria y, procedimiento del mismo.
CA2522755A1 (en) * 2003-04-16 2004-11-04 Drexel University Acoustic blood analyzer for assessing blood properties
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US7399637B2 (en) * 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
CN2916635Y (zh) * 2006-06-09 2007-06-27 姚冬 凝血分析检测装置
JP4675946B2 (ja) * 2007-09-07 2011-04-27 独立行政法人産業技術総合研究所 粘度測定装置

Also Published As

Publication number Publication date
NI201200109A (es) 2013-02-15
CO6551732A2 (es) 2012-10-31
CR20120326A (es) 2012-09-24
US20110151491A1 (en) 2011-06-23
HN2012001269A (es) 2014-12-01
PE20121723A1 (es) 2012-12-11
BR112012014421B1 (pt) 2021-02-02
CA2780492A1 (en) 2011-06-23
CA2780492C (en) 2018-07-17
EP2513647A4 (en) 2013-09-04
WO2011075614A3 (en) 2011-10-13
EP2513647B1 (en) 2015-04-22
US8450078B2 (en) 2013-05-28
US20130267017A1 (en) 2013-10-10
BR112012014421B8 (pt) 2021-07-27
CN102687009A (zh) 2012-09-19
EP2513647A2 (en) 2012-10-24
AU2010330861B2 (en) 2013-09-26
JP2013515238A (ja) 2013-05-02
WO2011075614A2 (en) 2011-06-23
CN102687009B (zh) 2014-07-16
AU2010330861A1 (en) 2012-05-31
ES2543099T3 (es) 2015-08-14
HK1173497A1 (en) 2013-05-16
JP5655091B2 (ja) 2015-01-14
US9063161B2 (en) 2015-06-23
BR112012014421A2 (pt) 2017-12-19
MX2012007084A (es) 2012-10-15

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