CR20120326A - Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación - Google Patents

Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación

Info

Publication number
CR20120326A
CR20120326A CR20120326A CR20120326A CR20120326A CR 20120326 A CR20120326 A CR 20120326A CR 20120326 A CR20120326 A CR 20120326A CR 20120326 A CR20120326 A CR 20120326A CR 20120326 A CR20120326 A CR 20120326A
Authority
CR
Costa Rica
Prior art keywords
coagulation
portable device
evaluation method
monitoring
response
Prior art date
Application number
CR20120326A
Other languages
English (en)
Inventor
Robert Glenn Dennis
Thomas H Fischer
Joseph A Dacorta
Original Assignee
Entegrion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entegrion Inc filed Critical Entegrion Inc
Publication of CR20120326A publication Critical patent/CR20120326A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N2011/006—Determining flow properties indirectly by measuring other parameters of the system
    • G01N2011/008—Determining flow properties indirectly by measuring other parameters of the system optical properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Se describe un dispositivo, sistema y método en el cual muestras de sangre de volumen pequeño se someten a fuerzas de cizalladura y esfuerzos de cizalladura entre dos superficies planas paralelas a las cuales se imparten trayectorias de movimiento lineales. La formación de coágulos o la coagulación de la muestra se miden a partir del acoplamiento mecánico dinámico que ocurre entre las dos superficies planas paralelas.
CR20120326A 2009-12-18 2012-06-15 Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación CR20120326A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28778009P 2009-12-18 2009-12-18

Publications (1)

Publication Number Publication Date
CR20120326A true CR20120326A (es) 2012-09-24

Family

ID=44151642

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120326A CR20120326A (es) 2009-12-18 2012-06-15 Dispositivo portátil de monitorización de la coagulación y método de evaluación de la respuesta de coagulación

Country Status (17)

Country Link
US (2) US8450078B2 (es)
EP (1) EP2513647B1 (es)
JP (1) JP5655091B2 (es)
CN (1) CN102687009B (es)
AU (1) AU2010330861B2 (es)
BR (1) BR112012014421B8 (es)
CA (1) CA2780492C (es)
CO (1) CO6551732A2 (es)
CR (1) CR20120326A (es)
EC (1) ECSP12011981A (es)
ES (1) ES2543099T3 (es)
HK (1) HK1173497A1 (es)
HN (1) HN2012001269A (es)
MX (1) MX2012007084A (es)
NI (1) NI201200109A (es)
PE (1) PE20121723A1 (es)
WO (1) WO2011075614A2 (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7892188B2 (en) * 2003-10-22 2011-02-22 Hemosonics, Llc Method and apparatus for characterization of clot formation
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
US10739358B2 (en) 2009-12-18 2020-08-11 Entegrion, Inc. Portable coagulation monitoring devices, systems, and methods
CA2795454C (en) 2010-04-08 2023-04-18 Hemosonics, Llc Hemostatic parameter display
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
AU2012364909B2 (en) 2011-02-15 2016-11-24 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
PT2676136T (pt) 2011-02-15 2021-03-25 Hemosonics Llc Dispositivos, sistemas e métodos para avaliação de hemostasia
WO2012159021A2 (en) 2011-05-19 2012-11-22 Hemosonics, Llc Portable hemostasis analyzer
JP5764674B2 (ja) * 2011-12-26 2015-08-19 パナソニックヘルスケアホールディングス株式会社 液体試料測定システム
EP2805158B8 (en) 2012-01-16 2020-10-07 Abram Scientific, Inc. Methods and devices for measuring physical properties of fluid
EP2926115B1 (en) 2012-11-30 2021-05-26 The University of North Carolina At Chapel Hill Methods and systems for determining physical properties of a specimen in a portable point of care diagnostic device
CN108680734B (zh) 2012-12-17 2021-06-25 雅培医护站股份有限公司 便携式临床分析系统的操作和核查
US9949674B2 (en) 2012-12-17 2018-04-24 Abbott Point Of Care Inc. Portable clinical analysis system for hematocrit measurement
US9885706B2 (en) 2012-12-17 2018-02-06 Abbott Point Of Care Inc. Portable clinical analysis system for immunometric measurement
EP2932259B1 (en) 2012-12-17 2019-11-13 Abbott Point Of Care, Inc. Spatial orientation determination in portable clinical analysis systems
US9904761B2 (en) 2012-12-17 2018-02-27 Abbot Point Of Care Inc. Self correction for spatial orientation and motion of portable clinical analyzers
KR101481240B1 (ko) * 2012-12-27 2015-01-19 고려대학교 산학협력단 마이크로 유동칩 기반 혈소판 기능 및 약물반응 검사 장치 및 방법
CN103487377B (zh) * 2013-10-11 2016-03-09 江苏英诺华医疗技术有限公司 一种全血凝血功能检测仪及检测方法
US10823743B1 (en) 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
PE20161194A1 (es) * 2013-11-15 2016-11-27 Entegrion Inc Dispositivos, sistemas y metodos portatiles de control de coagulacion
US9452199B2 (en) * 2014-01-17 2016-09-27 General Electric Company Platelet activation and growth factor release using electric pulses
JP6526717B2 (ja) 2014-05-05 2019-06-05 ヘモネティクス・コーポレーションＨａｅｍｏｎｅｔｉｃｓ Ｃｏｒｐｏｒａｔｉｏｎ 線維素溶解及び線溶亢進を検出するための方法及び試薬
BR112017004506B1 (pt) 2014-09-09 2023-12-19 Perosphere Technologies Inc Microchip de ensaio para a medição de coagulação em uma amostra de sangue ou plasma, dispositivo de microensaio para a medição de coagulação em uma amostra de sangue ou plasma de um indíviduo e método para medição de tempo de coagulação
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
WO2016077657A1 (en) * 2014-11-14 2016-05-19 Cora Healthcare, Inc. Apparatus and method to determine stroke subtype
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
CN105403691B (zh) * 2016-01-01 2017-08-18 赛奥生物科技（青岛）有限公司 一种血液试剂分析系统
CN106198943B (zh) * 2016-08-16 2019-11-12 中国科学院苏州生物医学工程技术研究所 一种血液动力学分析装置
GB2555870A (en) 2016-11-15 2018-05-16 Haemair Ltd Rheometer and method for the use thereof
EP3541443B1 (en) * 2016-11-17 2024-04-10 enicor GmbH Coated articles for blood coagulation testing and methods of preparing the same
CA3065331A1 (en) 2017-04-20 2018-10-25 Hemosonics, Llc Disposable system for analysis of hemostatic function
EP3830573A4 (en) * 2018-07-29 2022-02-23 KOC Universitesi INSTRUMENT FOR MICROFLUIDIC THROMBOELASTOMETRIC
US20210260589A1 (en) * 2020-02-26 2021-08-26 Emmanuel Mpock Method and Apparatus for Measuring Blood Coagulation
KR102414376B1 (ko) * 2020-05-26 2022-06-29 고려대학교 산학협력단 지혈 검사 장치
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023A (en) * 1847-03-20 Stocking-loom
JPH0743388B2 (ja) * 1990-05-29 1995-05-15 日立化成工業株式会社 血液凝固に伴うゲル化反応の測定法，測定装置及び測定用素子
FR2664982B1 (fr) * 1990-07-20 1994-04-29 Serbio Appareil de detection de changement de viscosite, par mesure d'un glissement relatif, en particulier pour la detection du temps de coagulation du sang.
US5838515A (en) * 1996-04-30 1998-11-17 Quantum Corporation PWM/linear driver for disk drive voice coil actuator
US6046051A (en) * 1997-06-27 2000-04-04 Hemosense, Inc. Method and device for measuring blood coagulation or lysis by viscosity changes
US6750053B1 (en) * 1999-11-15 2004-06-15 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
WO2001036666A1 (en) * 1999-11-15 2001-05-25 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
US6743596B1 (en) * 2000-10-27 2004-06-01 Biomerieux, Inc. Method of determining global coagulability hemostatic potential
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
ES2234349B1 (es) * 2002-04-18 2006-11-01 Servicio De Instrumentacion Hospitalaria, S.L. Dispositivo de medicion de tiempo de coagulacion y actividad plaquetaria y, procedimiento del mismo.
CA2522755A1 (en) * 2003-04-16 2004-11-04 Drexel University Acoustic blood analyzer for assessing blood properties
US20040228766A1 (en) * 2003-05-14 2004-11-18 Witty Thomas R. Point of care diagnostic platform
US7399637B2 (en) * 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
CN2916635Y (zh) * 2006-06-09 2007-06-27 姚冬 凝血分析检测装置
JP4675946B2 (ja) * 2007-09-07 2011-04-27 独立行政法人産業技術総合研究所 粘度測定装置

Also Published As

Publication number Publication date
BR112012014421B8 (pt) 2021-07-27
AU2010330861A1 (en) 2012-05-31
AU2010330861B2 (en) 2013-09-26
EP2513647A2 (en) 2012-10-24
US9063161B2 (en) 2015-06-23
CA2780492A1 (en) 2011-06-23
MX2012007084A (es) 2012-10-15
ECSP12011981A (es) 2012-08-31
US20110151491A1 (en) 2011-06-23
JP2013515238A (ja) 2013-05-02
US20130267017A1 (en) 2013-10-10
CA2780492C (en) 2018-07-17
EP2513647B1 (en) 2015-04-22
PE20121723A1 (es) 2012-12-11
CO6551732A2 (es) 2012-10-31
CN102687009B (zh) 2014-07-16
WO2011075614A2 (en) 2011-06-23
HK1173497A1 (en) 2013-05-16
EP2513647A4 (en) 2013-09-04
ES2543099T3 (es) 2015-08-14
US8450078B2 (en) 2013-05-28
NI201200109A (es) 2013-02-15
BR112012014421B1 (pt) 2021-02-02
BR112012014421A2 (pt) 2017-12-19
CN102687009A (zh) 2012-09-19
HN2012001269A (es) 2014-12-01
JP5655091B2 (ja) 2015-01-14
WO2011075614A3 (en) 2011-10-13

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