ECSP099692A - Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticas - Google Patents
Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticasInfo
- Publication number
- ECSP099692A ECSP099692A EC2009009692A ECSP099692A ECSP099692A EC SP099692 A ECSP099692 A EC SP099692A EC 2009009692 A EC2009009692 A EC 2009009692A EC SP099692 A ECSP099692 A EC SP099692A EC SP099692 A ECSP099692 A EC SP099692A
- Authority
- EC
- Ecuador
- Prior art keywords
- production
- pharmaceutical substances
- vinylloid
- new
- receiver links
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
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- C—CHEMISTRY; METALLURGY
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- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
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- C07D249/18—Benzotriazoles
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C—CHEMISTRY; METALLURGY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007018149A DE102007018149A1 (de) | 2007-04-16 | 2007-04-16 | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US12/103,667 US8084484B2 (en) | 2007-04-16 | 2008-04-15 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions |
EP2008002997 | 2008-04-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099692A true ECSP099692A (es) | 2009-11-30 |
Family
ID=41360190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009692A ECSP099692A (es) | 2007-04-16 | 2009-10-16 | Ligandos de receptor de vainilloide novedosos y su uso de los mismos para la produccion de sustancias farmaceuticas |
Country Status (14)
Country | Link |
---|---|
JP (1) | JP2010523727A (ru) |
KR (1) | KR20100016593A (ru) |
CN (1) | CN101679370A (ru) |
AU (1) | AU2008238250B2 (ru) |
BR (1) | BRPI0810035A2 (ru) |
CA (1) | CA2683461A1 (ru) |
CO (1) | CO6241154A2 (ru) |
EC (1) | ECSP099692A (ru) |
IL (1) | IL201505A0 (ru) |
MX (1) | MX2009011149A (ru) |
NZ (1) | NZ580411A (ru) |
RU (1) | RU2498982C2 (ru) |
WO (1) | WO2008125342A2 (ru) |
ZA (1) | ZA200907099B (ru) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007018149A1 (de) | 2007-04-16 | 2008-10-23 | Grünenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
US8946204B2 (en) | 2009-05-07 | 2015-02-03 | Gruenenthal Gmbh | Substituted phenylureas and phenylamides as vanilloid receptor ligands |
AR076752A1 (es) * | 2009-05-07 | 2011-07-06 | Gruenenthal Chemie | Fenilureas y fenilamidas sustituidas como ligandos del receptor de vanilloides. |
BR112014001714A2 (pt) | 2011-07-26 | 2017-02-14 | Gruenenthal Gmbh | derivados de carboxamida e ureia aromáticos bicíclicos substituídos como ligantes de receptor vaniloide |
US20130029961A1 (en) | 2011-07-26 | 2013-01-31 | Gruenenthal Gmbh | Substituted Heterocyclic Aza Compounds |
AR088701A1 (es) * | 2011-11-09 | 2014-06-25 | Gruenenthal Gmbh | Derivados de carboxamida y urea basados en pirazolilo, sustituidos, que contienen una porcion fenilo sustituida con un grupo que contiene n como ligandos del receptor de vanilloide |
US9487510B2 (en) * | 2012-03-05 | 2016-11-08 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic acetamides as kappa opioid receptor (KOR) agonists |
KR20160098506A (ko) * | 2013-12-20 | 2016-08-18 | 라보라토리오스 델 드라. 에스테브.에스.에이. | 통증에 대한 다양한 활성을 갖는 피페라진 유도체 |
CN107721919B (zh) * | 2017-10-30 | 2020-12-08 | 中国药科大学 | 苯基喹啉类trpv1拮抗剂及其制备方法和应用 |
KR102334947B1 (ko) * | 2020-04-22 | 2021-12-06 | 주식회사 제이맥켐 | Trpv1 길항제로서 벤즈이미다졸론계 시남아마이드 유도체 및 이를 유효성분으로 함유하는 통증의 치료 또는 예방용 약학적 조성물 |
RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
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EP1451156A4 (en) * | 2001-11-27 | 2005-05-25 | Merck & Co Inc | 4-AMINOQUINOLINE COMPOUNDS |
DE60325834D1 (de) * | 2002-02-20 | 2009-03-05 | Abbott Lab | Kondensierte azabicyclischeverbindungen als inhibitoren des vanilloid-rezeptors 1 (vr1) |
GB0206876D0 (en) * | 2002-03-22 | 2002-05-01 | Merck Sharp & Dohme | Therapeutic agents |
US6933311B2 (en) * | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
CN1813071A (zh) * | 2003-04-29 | 2006-08-02 | 奥克萨根有限公司 | 骨损伤遗传易感性的诊断方法 |
SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
KR20060027338A (ko) * | 2003-06-12 | 2006-03-27 | 아스텔라스세이야쿠 가부시키가이샤 | 벤즈 아미드 유도체 또는 그 염 |
US20050113576A1 (en) * | 2003-08-05 | 2005-05-26 | Chih-Hung Lee | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
GB0322016D0 (en) * | 2003-09-19 | 2003-10-22 | Merck Sharp & Dohme | New compounds |
WO2005044802A2 (en) * | 2003-11-08 | 2005-05-19 | Bayer Healthcare Ag | Tetrahydro-quinolinylurea derivatives as vrl antagonists |
US20050165015A1 (en) * | 2004-01-23 | 2005-07-28 | Ncube Mghele V. | Vanilloid receptor ligands and their use in treatments |
DE102005023943A1 (de) * | 2005-05-20 | 2006-11-23 | Grünenthal GmbH | Pentafluorsulfanyl-substituierte Verbindung und deren Verwendung zur Herstellung von Arzneimitteln |
NZ569327A (en) * | 2005-12-28 | 2011-09-30 | Vertex Pharma | 1-(benzo [d] [1,3] dioxol-5-yl) -n- (phenyl) cyclopropane- carboxamide derivatives and related compounds as modulators of ATP-binding cassette transporters for the treatment of cystic fibrosis |
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2008
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- 2008-04-16 WO PCT/EP2008/003027 patent/WO2008125342A2/de active Application Filing
- 2008-04-16 KR KR1020097023887A patent/KR20100016593A/ko not_active Application Discontinuation
- 2008-04-16 AU AU2008238250A patent/AU2008238250B2/en not_active Ceased
- 2008-04-16 MX MX2009011149A patent/MX2009011149A/es active IP Right Grant
- 2008-04-16 CN CN200880020483A patent/CN101679370A/zh active Pending
- 2008-04-16 NZ NZ580411A patent/NZ580411A/en not_active IP Right Cessation
- 2008-04-16 CA CA002683461A patent/CA2683461A1/en not_active Abandoned
- 2008-04-16 RU RU2009142023/04A patent/RU2498982C2/ru not_active IP Right Cessation
- 2008-04-16 JP JP2010503397A patent/JP2010523727A/ja not_active Ceased
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2009
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- 2009-10-16 EC EC2009009692A patent/ECSP099692A/es unknown
- 2009-10-22 CO CO09118505A patent/CO6241154A2/es active IP Right Grant
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CO6241154A2 (es) | 2011-01-20 |
IL201505A0 (en) | 2010-05-31 |
RU2009142023A (ru) | 2011-05-27 |
AU2008238250A1 (en) | 2008-10-23 |
MX2009011149A (es) | 2009-10-30 |
BRPI0810035A2 (pt) | 2016-07-26 |
WO2008125342A3 (de) | 2009-01-15 |
CA2683461A1 (en) | 2008-10-23 |
AU2008238250B2 (en) | 2013-01-24 |
ZA200907099B (en) | 2013-03-27 |
RU2498982C2 (ru) | 2013-11-20 |
NZ580411A (en) | 2012-06-29 |
CN101679370A (zh) | 2010-03-24 |
WO2008125342A2 (de) | 2008-10-23 |
JP2010523727A (ja) | 2010-07-15 |
KR20100016593A (ko) | 2010-02-12 |
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