ECSP034547A - Derivados de pirazol para el tratamiento de enfermedades virales - Google Patents
Derivados de pirazol para el tratamiento de enfermedades viralesInfo
- Publication number
- ECSP034547A ECSP034547A EC2003004547A ECSP034547A ECSP034547A EC SP034547 A ECSP034547 A EC SP034547A EC 2003004547 A EC2003004547 A EC 2003004547A EC SP034547 A ECSP034547 A EC SP034547A EC SP034547 A ECSP034547 A EC SP034547A
- Authority
- EC
- Ecuador
- Prior art keywords
- alkyl
- optionally substituted
- aryl
- heterocyclyl
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
La invención se refiere a nuevos y conocidos derivados de pirazol, un proceso para su elaboración, las composiciones farmacéuticas y el uso de tales compuestos en medicina, en particular, los compuestos de fórmula I son inhibidores de la enzima transcriptasa reversa del virus de inmunodeficiencia humana que esta implicada en la replicación viral. Por consiguiente los compuestos de esta invención se pueden usar favorablemente como agentes terapéuticos para los procesos mediados por el virus de inmunodeficiencia humana (VIH. Específicamente la invención describe el uso de compuestos de fórmula I en donde (Gráfico) R1 es un C1-12- alquilo sustituido opcionalmente, arilo, heterociclilo o C1-4-alquilo sustituido con fenilo opcionalmente sustituido; R3 es C1-12-alquilo o C1-4alcoxi-C1-4-alquilo; A indica un grupo seleccionado de CH2-(aril-C1-4-alquilamino), CH2-(aril-C1-4-alcoxi), C1-4-alquilo sustituido con arilo opcionalmente sustituido o con heterociclilo opccionalmente sustituido; o A indica un grupo de fórmula CH2-U-heterociclilo, en donde U representa O, S o NR", donde R" es hidrógeno o C1-4 -alquilo; oA indica un grupo de fórmula CH(V)Z, en donde V representa OH o F, y en donde Z representa arilo o heterociclilo sustituido opcionalmente; X representa SoO; para el tratamiento de enfermedades mediadas por el virus de la inmunodeficiencia humana (VIH) o para la preparación de un medicamento para dicho tratamiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0024795.7A GB0024795D0 (en) | 2000-10-10 | 2000-10-10 | Pyrazole derivatives for the treatment of viral diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP034547A true ECSP034547A (es) | 2003-05-26 |
Family
ID=9900999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2003004547A ECSP034547A (es) | 2000-10-10 | 2003-04-08 | Derivados de pirazol para el tratamiento de enfermedades virales |
Country Status (29)
Country | Link |
---|---|
US (2) | US6699887B2 (es) |
EP (1) | EP1326843A1 (es) |
JP (1) | JP4015548B2 (es) |
KR (1) | KR100534158B1 (es) |
CN (2) | CN1191239C (es) |
AR (1) | AR030858A1 (es) |
AU (2) | AU2165102A (es) |
BR (1) | BR0114483A (es) |
CA (1) | CA2423515A1 (es) |
CZ (1) | CZ20031297A3 (es) |
EC (1) | ECSP034547A (es) |
GB (1) | GB0024795D0 (es) |
GT (1) | GT200100201A (es) |
HK (1) | HK1061021A1 (es) |
HR (1) | HRP20030251A2 (es) |
HU (1) | HUP0302722A2 (es) |
IL (1) | IL154875A0 (es) |
MA (1) | MA26951A1 (es) |
MX (1) | MXPA03003070A (es) |
NO (1) | NO20031615L (es) |
NZ (1) | NZ524740A (es) |
PA (1) | PA8530301A1 (es) |
PE (1) | PE20020750A1 (es) |
PL (1) | PL362918A1 (es) |
RU (1) | RU2270832C2 (es) |
UY (1) | UY26956A1 (es) |
WO (1) | WO2002030907A1 (es) |
YU (1) | YU27203A (es) |
ZA (1) | ZA200302519B (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60138658D1 (de) * | 2000-09-29 | 2009-06-18 | Topotarget Uk Ltd | Carbaminsäurederivate enthaltend eine Amidgruppe zur Behandlung von Malaria |
GB0113524D0 (en) * | 2001-06-04 | 2001-07-25 | Hoffmann La Roche | Pyrazole derivatives |
BR0314709A (pt) * | 2002-09-26 | 2005-07-26 | Pfizer | Derivados de pirazol |
JP2006505625A (ja) | 2002-09-26 | 2006-02-16 | ファイザー・インク | Hiv感染症を治療するためのピラゾールアミド |
US7230025B2 (en) | 2002-09-26 | 2007-06-12 | Pfizer, Inc. | Pyrazole derivatives |
US6933312B2 (en) | 2002-10-07 | 2005-08-23 | Agouron Pharmaceuticals, Inc. | Pyrazole derivatives |
GB0223232D0 (en) * | 2002-10-07 | 2002-11-13 | Pfizer Ltd | Chemical compounds |
GB0223234D0 (en) * | 2002-10-07 | 2002-11-13 | Pfizer Ltd | Chemical compounds |
TW200423930A (en) * | 2003-02-18 | 2004-11-16 | Hoffmann La Roche | Non-nucleoside reverse transcriptase inhibitors |
EP1608629A1 (en) | 2003-03-24 | 2005-12-28 | F. Hoffmann-La Roche Ag | Benzyl-pyridazinons as reverse transcriptase inhibitors |
US7220772B2 (en) | 2003-09-05 | 2007-05-22 | Pfizer, Inc. | Pyrazole derivatives |
CN1976938B (zh) * | 2004-07-01 | 2012-08-15 | 第一三共株式会社 | 具有pde7抑制活性的噻吩并吡唑衍生物 |
US20070005049A1 (en) * | 2005-06-30 | 2007-01-04 | Comben Richard H | Apparatus and Method of Treating Urinary Incontinence by Heating Urethra |
NZ574207A (en) * | 2006-07-05 | 2010-10-29 | Pfizer Prod Inc | Pyrazole derivatives as cytochrome p450 inhibitors |
PT2057125E (pt) | 2006-08-16 | 2011-05-31 | Hoffmann La Roche | Inibidores n?o nucle?sidos de transcriptase inversa |
GB0713479D0 (en) * | 2007-07-11 | 2007-08-22 | Syngenta Participations Ag | Substituted aromatic heterocyclic compounds as fungicides |
KR101610415B1 (ko) | 2007-12-21 | 2016-04-07 | 에프. 호프만-라 로슈 아게 | 헤테로사이클릭 항바이러스 화합물 |
GB0823000D0 (en) * | 2008-12-17 | 2009-01-28 | Syngenta Participations Ag | Isothiazole and pyrazole derivatives with plant growth regulating properties |
AU2010218853A1 (en) | 2009-02-25 | 2011-10-06 | Daiichi Sankyo Company, Limited | Tricyclic pyrazolopyrimidine derivative |
FR2951549B1 (fr) | 2009-10-15 | 2013-08-23 | Olivier Schussler | Procede d'obtention de bioprotheses medicales implantables |
JPWO2012026433A1 (ja) | 2010-08-23 | 2013-10-28 | 第一三共株式会社 | 三環性ピラゾロピリミジン誘導体のフリー体結晶 |
JP5701884B2 (ja) | 2010-08-23 | 2015-04-15 | 第一三共株式会社 | 三環性ピラゾロピリミジン誘導体の結晶 |
WO2014074628A1 (en) * | 2012-11-08 | 2014-05-15 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Compounds for treating hiv and methods for using the compounds |
US9925190B2 (en) | 2015-02-16 | 2018-03-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Small molecules targeting HIV-1 Nef |
BR112020019804A2 (pt) | 2018-03-30 | 2021-01-05 | Sumitomo Chemical Company, Limited | Composto heterocíclico e composição de controle de peste artrópode contendo o mesmo |
WO2020081856A1 (en) * | 2018-10-18 | 2020-04-23 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Inhibitors of hiv-1 nef for the treatment of hiv disease |
FR3121927B1 (fr) | 2021-04-19 | 2023-03-31 | Eiffage Genie Civil Terrassement | Procédé d’inertage des boues d’excavation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0627423A4 (en) | 1992-01-22 | 1995-02-15 | Nissan Chemical Ind Ltd | SUBSTITUTED PYRAZOLE DERIVATIVES AND BACTERICIDES FOR AGRICULTURE AND GARDENING. |
US6005109A (en) | 1997-10-30 | 1999-12-21 | Pflizer Inc. | Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity |
WO2006027423A1 (fr) * | 2004-08-09 | 2006-03-16 | Simag Developpement | Dispositif de saisie comportant un capteur optique suivi d’un moyen de filtrage |
-
2000
- 2000-10-10 GB GBGB0024795.7A patent/GB0024795D0/en not_active Ceased
-
2001
- 2001-09-20 US US09/956,656 patent/US6699887B2/en not_active Expired - Fee Related
- 2001-10-04 PL PL01362918A patent/PL362918A1/xx not_active Application Discontinuation
- 2001-10-04 BR BR0114483-9A patent/BR0114483A/pt not_active Application Discontinuation
- 2001-10-04 JP JP2002534293A patent/JP4015548B2/ja not_active Expired - Fee Related
- 2001-10-04 AU AU2165102A patent/AU2165102A/xx active Pending
- 2001-10-04 AU AU2002221651A patent/AU2002221651B2/en not_active Ceased
- 2001-10-04 CZ CZ20031297A patent/CZ20031297A3/cs unknown
- 2001-10-04 YU YU27203A patent/YU27203A/sh unknown
- 2001-10-04 CN CNB018171710A patent/CN1191239C/zh not_active Expired - Fee Related
- 2001-10-04 CA CA002423515A patent/CA2423515A1/en not_active Abandoned
- 2001-10-04 EP EP01986680A patent/EP1326843A1/en not_active Withdrawn
- 2001-10-04 CN CNA2005100088329A patent/CN1680333A/zh active Pending
- 2001-10-04 NZ NZ524740A patent/NZ524740A/en unknown
- 2001-10-04 WO PCT/EP2001/011474 patent/WO2002030907A1/en active IP Right Grant
- 2001-10-04 IL IL15487501A patent/IL154875A0/xx unknown
- 2001-10-04 MX MXPA03003070A patent/MXPA03003070A/es active IP Right Grant
- 2001-10-04 HU HU0302722A patent/HUP0302722A2/hu unknown
- 2001-10-04 KR KR10-2003-7004984A patent/KR100534158B1/ko not_active IP Right Cessation
- 2001-10-04 RU RU2003112610/04A patent/RU2270832C2/ru not_active IP Right Cessation
- 2001-10-05 PE PE2001000993A patent/PE20020750A1/es not_active Application Discontinuation
- 2001-10-05 AR ARP010104697A patent/AR030858A1/es not_active Application Discontinuation
- 2001-10-09 UY UY26956A patent/UY26956A1/es not_active Application Discontinuation
- 2001-10-09 PA PA20018530301A patent/PA8530301A1/es unknown
- 2001-10-09 GT GT200100201A patent/GT200100201A/es unknown
-
2003
- 2003-03-31 ZA ZA200302519A patent/ZA200302519B/en unknown
- 2003-04-03 HR HR20030251A patent/HRP20030251A2/hr not_active Application Discontinuation
- 2003-04-07 MA MA27096A patent/MA26951A1/fr unknown
- 2003-04-08 EC EC2003004547A patent/ECSP034547A/es unknown
- 2003-04-09 NO NO20031615A patent/NO20031615L/no unknown
-
2004
- 2004-01-27 US US10/766,712 patent/US7183296B2/en not_active Expired - Fee Related
- 2004-06-03 HK HK04103975A patent/HK1061021A1/xx not_active IP Right Cessation
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