EA202191656A1 - Анти-il-36 антитела и способы их применения - Google Patents

Анти-il-36 антитела и способы их применения

Info

Publication number
EA202191656A1
EA202191656A1 EA202191656A EA202191656A EA202191656A1 EA 202191656 A1 EA202191656 A1 EA 202191656A1 EA 202191656 A EA202191656 A EA 202191656A EA 202191656 A EA202191656 A EA 202191656A EA 202191656 A1 EA202191656 A1 EA 202191656A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibodies
methods
application
proteins
binding
Prior art date
Application number
EA202191656A
Other languages
English (en)
Russian (ru)
Inventor
Цзинвэй Вивиан Ли
Жермена Фу-Келли
Луиза Шарф
Тина Тай
Ашка Пател
Шашанк Бхарилл
Эрик Эдвард Каррер
Original Assignee
23Эндми, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 23Эндми, Инк. filed Critical 23Эндми, Инк.
Publication of EA202191656A1 publication Critical patent/EA202191656A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EA202191656A 2018-12-21 2019-12-19 Анти-il-36 антитела и способы их применения EA202191656A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862784316P 2018-12-21 2018-12-21
PCT/US2019/067435 WO2020132220A1 (en) 2018-12-21 2019-12-19 Anti-il-36 antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
EA202191656A1 true EA202191656A1 (ru) 2021-10-26

Family

ID=69187940

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202191656A EA202191656A1 (ru) 2018-12-21 2019-12-19 Анти-il-36 антитела и способы их применения

Country Status (20)

Country Link
US (2) US11884719B2 (https=)
EP (1) EP3898673A1 (https=)
JP (1) JP2022514950A (https=)
KR (1) KR20210107721A (https=)
CN (1) CN113454113A (https=)
AR (1) AR123405A1 (https=)
AU (1) AU2019405782A1 (https=)
BR (1) BR112021010374A2 (https=)
CA (1) CA3120474A1 (https=)
CL (1) CL2021001615A1 (https=)
CO (1) CO2021007882A2 (https=)
EA (1) EA202191656A1 (https=)
IL (1) IL283884A (https=)
MX (1) MX2021007589A (https=)
PE (1) PE20211295A1 (https=)
PH (1) PH12021551422A1 (https=)
SG (1) SG11202106100VA (https=)
TW (1) TW202035460A (https=)
WO (1) WO2020132220A1 (https=)
ZA (1) ZA202103311B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115925932A (zh) 2015-04-15 2023-04-07 安奈普泰斯生物有限公司 针对白细胞介素36受体（il-36r）的抗体
WO2021259880A1 (en) * 2020-06-22 2021-12-30 Almirall, S.A. Anti-il-36 antibodies and methods of use thereof
BR112022026999A2 (pt) * 2020-07-17 2023-01-24 Boehringer Ingelheim Int Anticorpos anti-il-36r para tratamento de dermatoses neutrofílicas
CN112094349B (zh) * 2020-11-04 2021-02-09 上海华奥泰生物药业股份有限公司 靶向于白介素36r的抗体及其制备方法和应用
WO2022150644A1 (en) * 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for acne
WO2022150642A1 (en) * 2021-01-08 2022-07-14 Anaptysbio, Inc. Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa

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Also Published As

Publication number Publication date
BR112021010374A2 (pt) 2021-08-24
EP3898673A1 (en) 2021-10-27
US20240132582A1 (en) 2024-04-25
MX2021007589A (es) 2021-12-10
PE20211295A1 (es) 2021-07-20
US11884719B2 (en) 2024-01-30
CA3120474A1 (en) 2020-06-25
KR20210107721A (ko) 2021-09-01
JP2022514950A (ja) 2022-02-16
CL2021001615A1 (es) 2021-11-26
ZA202103311B (en) 2022-10-26
TW202035460A (zh) 2020-10-01
IL283884A (en) 2021-07-29
AR123405A1 (es) 2022-11-30
SG11202106100VA (en) 2021-07-29
CO2021007882A2 (es) 2021-06-21
CN113454113A (zh) 2021-09-28
PH12021551422A1 (en) 2022-05-02
WO2020132220A9 (en) 2020-09-10
AU2019405782A1 (en) 2021-06-17
WO2020132220A1 (en) 2020-06-25
US20200199217A1 (en) 2020-06-25

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