EA201491643A1 - Идентификация мутаций канал-опсина-2 (chop2) и способы применения - Google Patents
Идентификация мутаций канал-опсина-2 (chop2) и способы примененияInfo
- Publication number
- EA201491643A1 EA201491643A1 EA201491643A EA201491643A EA201491643A1 EA 201491643 A1 EA201491643 A1 EA 201491643A1 EA 201491643 A EA201491643 A EA 201491643A EA 201491643 A EA201491643 A EA 201491643A EA 201491643 A1 EA201491643 A1 EA 201491643A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- chop2
- opsin
- canal
- mutations
- identification
- Prior art date
Links
- 230000035772 mutation Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261606663P | 2012-03-05 | 2012-03-05 | |
| PCT/US2013/029171 WO2013134295A1 (en) | 2012-03-05 | 2013-03-05 | Identification of channelrhodopsin-2 (chop2) mutations and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201491643A1 true EA201491643A1 (ru) | 2015-02-27 |
Family
ID=47892055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201491643A EA201491643A1 (ru) | 2012-03-05 | 2013-03-05 | Идентификация мутаций канал-опсина-2 (chop2) и способы применения |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US10947281B2 (https=) |
| EP (1) | EP2822964B1 (https=) |
| JP (3) | JP6395611B2 (https=) |
| KR (1) | KR102137717B1 (https=) |
| CN (2) | CN111378020A (https=) |
| AU (4) | AU2013230112A1 (https=) |
| CA (1) | CA2866405A1 (https=) |
| DK (1) | DK2822964T3 (https=) |
| EA (1) | EA201491643A1 (https=) |
| ES (1) | ES2703324T3 (https=) |
| HU (1) | HUE040487T2 (https=) |
| MX (1) | MX360085B (https=) |
| NZ (1) | NZ629843A (https=) |
| PL (1) | PL2822964T3 (https=) |
| PT (1) | PT2822964T (https=) |
| WO (1) | WO2013134295A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101484005A (zh) | 2006-05-04 | 2009-07-15 | 韦恩州立大学 | 通过向体内递送视紫红质核酸恢复视觉响应 |
| WO2011140279A1 (en) | 2010-05-04 | 2011-11-10 | Wayne State University | Aav-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells |
| CA2866405A1 (en) * | 2012-03-05 | 2013-09-12 | Wayne State University | Identification of channelopsin-2 (chop2) mutations and methods of use |
| EP2968476B1 (en) | 2013-03-14 | 2021-05-05 | Wayne State University | A plasmin for use in enhancing delivery of therapeutic compounds to the eyes or for improving vision |
| JP6469669B2 (ja) | 2013-07-08 | 2019-02-13 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | オキシムエステル光開始剤 |
| EP4678754A3 (en) | 2014-03-11 | 2026-04-08 | Wayne State University | A modified mglur6 promoter and methods of use |
| US20170319669A1 (en) | 2016-05-03 | 2017-11-09 | Wayne State University | Method of enhancing viral-mediated gene delivery |
| CN109476720A (zh) * | 2016-06-03 | 2019-03-15 | 马克斯-普朗克科学促进协会 | 通道视紫红质的突变型光诱导离子通道 |
| EP3504227A1 (en) * | 2016-08-29 | 2019-07-03 | Wayne State University | Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof |
| JP6779546B2 (ja) * | 2016-11-06 | 2020-11-04 | ナノスコープ テクノロジーズ エルエルシーＮａｎｏｓｃｏｐｅ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ | 視力回復のための多特性オプシンによる光遺伝学的調節及びその別の用途 |
| US20200115419A1 (en) * | 2017-04-12 | 2020-04-16 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | New optogenetic tool |
| DK3720428T3 (da) * | 2017-12-04 | 2023-03-20 | Salvat Lab Sa | Oftalmisk topisk sammensætning omfattende dobesilsyre til behandling af sygdomme i det bageste øjensegment |
| JP6567153B1 (ja) * | 2018-09-28 | 2019-08-28 | 学校法人東北工業大学 | 対象化合物の特性の予測を行うための方法、コンピュータシステム、プログラム |
| EP4704877A2 (en) * | 2023-04-24 | 2026-03-11 | Nanoscope Therapeutics Inc. | Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4498919A (en) | 1983-10-31 | 1985-02-12 | Corning Glass Works | Method for making colored photochromic prescription ophthalmic lenses |
| US6610287B1 (en) | 1990-04-16 | 2003-08-26 | The General Hospital Corporation | Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication |
| US5827702A (en) | 1994-10-31 | 1998-10-27 | Genentech, Inc. | Ocular gene therapy |
| EP0977880A2 (en) | 1997-04-21 | 2000-02-09 | University Of Florida | Materials and methods for treatment of retinal diseases |
| CA2346262A1 (en) | 1998-09-17 | 2000-03-23 | University Of Florida | Methods for treatment of degenerative retinal diseases |
| US7056502B2 (en) | 2000-04-28 | 2006-06-06 | The Trustees Of The University Of Pennsylvania | Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids |
| WO2002082904A2 (en) | 2001-04-13 | 2002-10-24 | The Trustees Of The University Of Pennsylvania | Method of treating or retarding the development of blindness |
| AU2002323210A1 (en) | 2001-08-16 | 2003-03-03 | Sloan Kettering Institute For Cancer Research | Bio-synthetic photostimulators and methods of use |
| DE10216005A1 (de) | 2002-04-11 | 2003-10-30 | Max Planck Gesellschaft | Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle |
| WO2004009022A2 (en) | 2002-07-18 | 2004-01-29 | The General Hospital Corp. | Method for augmenting vision in persons suffering from photoreceptor cell degeneration |
| US7186699B2 (en) | 2003-06-03 | 2007-03-06 | Cell Genesys, Inc. | Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes |
| US7427138B2 (en) | 2003-11-05 | 2008-09-23 | Neurovision, Inc. | Method and apparatus for improving visual perception |
| EP1919497B1 (en) | 2005-07-22 | 2020-02-12 | The Board of Trustees of the Leland Stanford Junior University | Light-activated cation channel and uses thereof |
| CN101484005A (zh) | 2006-05-04 | 2009-07-15 | 韦恩州立大学 | 通过向体内递送视紫红质核酸恢复视觉响应 |
| WO2011140279A1 (en) * | 2010-05-04 | 2011-11-10 | Wayne State University | Aav-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells |
| KR101945962B1 (ko) * | 2010-09-08 | 2019-02-08 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | 돌연변이 채널로돕신 2 |
| CA2866405A1 (en) * | 2012-03-05 | 2013-09-12 | Wayne State University | Identification of channelopsin-2 (chop2) mutations and methods of use |
| KR101639859B1 (ko) | 2014-03-06 | 2016-07-14 | 포항공과대학교 산학협력단 | 광 자극에 의한 미토콘드리아 활성의 시공간적 가역 조절 방법 |
-
2013
- 2013-03-05 CA CA2866405A patent/CA2866405A1/en active Pending
- 2013-03-05 NZ NZ629843A patent/NZ629843A/en unknown
- 2013-03-05 US US14/383,211 patent/US10947281B2/en active Active
- 2013-03-05 EP EP13710253.9A patent/EP2822964B1/en active Active
- 2013-03-05 MX MX2014010664A patent/MX360085B/es active IP Right Grant
- 2013-03-05 CN CN202010025519.0A patent/CN111378020A/zh active Pending
- 2013-03-05 EA EA201491643A patent/EA201491643A1/ru unknown
- 2013-03-05 KR KR1020147027985A patent/KR102137717B1/ko active Active
- 2013-03-05 PT PT13710253T patent/PT2822964T/pt unknown
- 2013-03-05 AU AU2013230112A patent/AU2013230112A1/en not_active Abandoned
- 2013-03-05 JP JP2014561051A patent/JP6395611B2/ja active Active
- 2013-03-05 DK DK13710253.9T patent/DK2822964T3/en active
- 2013-03-05 WO PCT/US2013/029171 patent/WO2013134295A1/en not_active Ceased
- 2013-03-05 PL PL13710253T patent/PL2822964T3/pl unknown
- 2013-03-05 ES ES13710253T patent/ES2703324T3/es active Active
- 2013-03-05 CN CN201380022635.5A patent/CN104334575A/zh active Pending
- 2013-03-05 HU HUE13710253A patent/HUE040487T2/hu unknown
-
2017
- 2017-10-06 AU AU2017239601A patent/AU2017239601B2/en active Active
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2018
- 2018-04-23 JP JP2018082403A patent/JP2018134098A/ja not_active Withdrawn
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2019
- 2019-07-01 JP JP2019123061A patent/JP2019193656A/ja active Pending
- 2019-08-14 AU AU2019216638A patent/AU2019216638B2/en active Active
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2021
- 2021-03-15 US US17/202,064 patent/US20220033449A1/en not_active Abandoned
- 2021-10-07 AU AU2021245195A patent/AU2021245195B2/en active Active
-
2024
- 2024-04-18 US US18/639,381 patent/US20250066431A1/en active Pending
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