PL2822964T3 - Identyfikacja mutacji opsyny kanałowej 2 (chop2) i sposoby stosowania - Google Patents

Identyfikacja mutacji opsyny kanałowej 2 (chop2) i sposoby stosowania

Info

Publication number
PL2822964T3
PL2822964T3 PL13710253T PL13710253T PL2822964T3 PL 2822964 T3 PL2822964 T3 PL 2822964T3 PL 13710253 T PL13710253 T PL 13710253T PL 13710253 T PL13710253 T PL 13710253T PL 2822964 T3 PL2822964 T3 PL 2822964T3
Authority
PL
Poland
Prior art keywords
chop2
channelrhodopsin
mutations
identification
methods
Prior art date
Application number
PL13710253T
Other languages
English (en)
Inventor
Zhuo-Hua Pan
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Publication of PL2822964T3 publication Critical patent/PL2822964T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL13710253T 2012-03-05 2013-03-05 Identyfikacja mutacji opsyny kanałowej 2 (chop2) i sposoby stosowania PL2822964T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606663P 2012-03-05 2012-03-05
EP13710253.9A EP2822964B1 (en) 2012-03-05 2013-03-05 Identification of channelrhodopsin-2 (chop2) mutations and methods of use
PCT/US2013/029171 WO2013134295A1 (en) 2012-03-05 2013-03-05 Identification of channelrhodopsin-2 (chop2) mutations and methods of use

Publications (1)

Publication Number Publication Date
PL2822964T3 true PL2822964T3 (pl) 2019-05-31

Family

ID=47892055

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13710253T PL2822964T3 (pl) 2012-03-05 2013-03-05 Identyfikacja mutacji opsyny kanałowej 2 (chop2) i sposoby stosowania

Country Status (16)

Country Link
US (3) US10947281B2 (pl)
EP (1) EP2822964B1 (pl)
JP (3) JP6395611B2 (pl)
KR (1) KR102137717B1 (pl)
CN (2) CN104334575A (pl)
AU (4) AU2013230112A1 (pl)
CA (1) CA2866405A1 (pl)
DK (1) DK2822964T3 (pl)
EA (1) EA201491643A1 (pl)
ES (1) ES2703324T3 (pl)
HU (1) HUE040487T2 (pl)
MX (1) MX360085B (pl)
NZ (1) NZ629843A (pl)
PL (1) PL2822964T3 (pl)
PT (1) PT2822964T (pl)
WO (1) WO2013134295A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2685900A1 (en) 2006-05-04 2007-11-15 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
DK2822964T3 (en) 2012-03-05 2018-12-10 Univ Wayne State IDENTIFICATION OF CHANNEL RHODOPSIN-2- (CHOP2) MUTATIONS AND METHODS OF USE
EP2968476B1 (en) 2013-03-14 2021-05-05 Wayne State University A plasmin for use in enhancing delivery of therapeutic compounds to the eyes or for improving vision
WO2015004565A1 (en) 2013-07-08 2015-01-15 Basf Se Oxime ester photoinitiators
CA3234028A1 (en) 2014-03-11 2015-09-17 Wayne State University A modified mglur6 promoter and methods of use
MX2018013352A (es) 2016-05-03 2019-08-01 Univ Wayne State Metodo para mejorar suministro de genes mediado por virus en el ojo usando inhibidores de proteosoma.
KR20190020702A (ko) * 2016-06-03 2019-03-04 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. 채널로돕신의 돌연변이 광-유도성 이온 채널
KR102877327B1 (ko) * 2016-08-29 2025-10-27 웨인 스테이트 유니버시티 개선된 광 민감성을 갖는 채널옵신 변이체에서의 돌연변이의 확인 및 이의 용도
US11180537B2 (en) * 2016-11-06 2021-11-23 Nancoscope Technologies LLC Optogenetic modulation by Multi-Characteristic Opsins for vision restoration and other applications
WO2018189247A1 (en) * 2017-04-12 2018-10-18 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. New optogenetic tool
PT3720428T (pt) * 2017-12-04 2023-04-03 Salvat Lab Sa Composição tópica oftálmica compreendendo ácido dobesílico para tratamento de doenças do segmento posterior do olho
JP6567153B1 (ja) * 2018-09-28 2019-08-28 学校法人東北工業大学 対象化合物の特性の予測を行うための方法、コンピュータシステム、プログラム
WO2024226667A2 (en) * 2023-04-24 2024-10-31 Nanoscope Therapeutics Inc. Optogenetic modulation by multi-characteristic opsins for vision restoration and other applications thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
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US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US4498919A (en) 1983-10-31 1985-02-12 Corning Glass Works Method for making colored photochromic prescription ophthalmic lenses
US6610287B1 (en) 1990-04-16 2003-08-26 The General Hospital Corporation Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
US5827702A (en) 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
AU7467598A (en) 1997-04-21 1998-11-13 University Of Florida Materials and methods for treatment of retinal diseases
NZ511037A (en) 1998-09-17 2005-02-25 Univ Florida Methods for treatment of degenerative retinal diseases
WO2001083692A2 (en) 2000-04-28 2001-11-08 The Trustees Of The University Of Pennsylvania Recombinant aav vectors with aav5 capsids and aav5 vectors pseudotyped in heterologous capsids
CA2442670A1 (en) 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
WO2003016486A2 (en) 2001-08-16 2003-02-27 Sloan Kettering Institute For Cancer Research Bio-synthetic photostimulators and methods of use
DE10216005A1 (de) 2002-04-11 2003-10-30 Max Planck Gesellschaft Verwendung von biologischen Photorezeptoren als direkt lichtgesteuerte Ionenkanäle
WO2004009022A2 (en) 2002-07-18 2004-01-29 The General Hospital Corp. Method for augmenting vision in persons suffering from photoreceptor cell degeneration
US7186699B2 (en) 2003-06-03 2007-03-06 Cell Genesys, Inc. Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
US7427138B2 (en) 2003-11-05 2008-09-23 Neurovision, Inc. Method and apparatus for improving visual perception
EP2465925A1 (en) 2005-07-22 2012-06-20 The Board Of Trustees Of The Leland Light-activated cation channel and uses thereof
CA2685900A1 (en) 2006-05-04 2007-11-15 Wayne State University Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
US9453241B2 (en) 2010-05-04 2016-09-27 Wayne State University AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells
US8748578B2 (en) * 2010-09-08 2014-06-10 Max-Planck-Gesellschaft zur Foerderrung der Wissenschaften e.V. Mutant channelrhodopsin 2
DK2822964T3 (en) * 2012-03-05 2018-12-10 Univ Wayne State IDENTIFICATION OF CHANNEL RHODOPSIN-2- (CHOP2) MUTATIONS AND METHODS OF USE
KR101639859B1 (ko) * 2014-03-06 2016-07-14 포항공과대학교 산학협력단 광 자극에 의한 미토콘드리아 활성의 시공간적 가역 조절 방법

Also Published As

Publication number Publication date
DK2822964T3 (en) 2018-12-10
AU2021245195A1 (en) 2021-11-04
HK1205744A1 (en) 2015-12-24
MX2014010664A (es) 2015-03-06
JP6395611B2 (ja) 2018-09-26
US20220033449A1 (en) 2022-02-03
CA2866405A1 (en) 2013-09-12
PT2822964T (pt) 2018-11-29
US10947281B2 (en) 2021-03-16
KR102137717B1 (ko) 2020-07-27
MX360085B (es) 2018-10-10
ES2703324T3 (es) 2019-03-08
WO2013134295A1 (en) 2013-09-12
CN111378020A (zh) 2020-07-07
JP2019193656A (ja) 2019-11-07
AU2021245195B2 (en) 2023-09-28
NZ727041A (en) 2022-01-28
KR20140132401A (ko) 2014-11-17
AU2017239601B2 (en) 2019-05-16
EA201491643A1 (ru) 2015-02-27
HUE040487T2 (hu) 2019-03-28
EP2822964A1 (en) 2015-01-14
US20250066431A1 (en) 2025-02-27
AU2017239601A1 (en) 2017-10-26
US20150044181A1 (en) 2015-02-12
EP2822964B1 (en) 2018-08-22
AU2019216638A1 (en) 2019-09-05
CN104334575A (zh) 2015-02-04
JP2018134098A (ja) 2018-08-30
JP2015510759A (ja) 2015-04-13
AU2019216638B2 (en) 2021-07-08
NZ629843A (en) 2017-03-31
AU2013230112A1 (en) 2014-09-25

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