EA201300780A1 - Способ получения индуцированных плюрипотентных стволовых клеток и дифференцированных клеток - Google Patents
Способ получения индуцированных плюрипотентных стволовых клеток и дифференцированных клетокInfo
- Publication number
- EA201300780A1 EA201300780A1 EA201300780A EA201300780A EA201300780A1 EA 201300780 A1 EA201300780 A1 EA 201300780A1 EA 201300780 A EA201300780 A EA 201300780A EA 201300780 A EA201300780 A EA 201300780A EA 201300780 A1 EA201300780 A1 EA 201300780A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cells
- pluripotent stem
- induced pluripotent
- differentiated
- stem cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Представлены способы получения iPSCs и представляющих интерес дифференцированных клеток путем перепрограммирования донорских клеток, полученных неинвазивным способом. В частности, донорские клетки представляют собой отслоившиеся эпителиальные клетки из мочи (мочевые клетки). Дифференцированные клетки могут быть получены путем дифференцировки перепрограммированных iPSCs или путем прямого перепрограммирования мочевых клеток.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNPCT/CN2010/002226 | 2010-12-31 | ||
EP11152519A EP2481795A1 (en) | 2011-01-28 | 2011-01-28 | Method of generating induced pluripotent stem cells and differentiated cells |
PCT/EP2011/073962 WO2012089669A1 (en) | 2010-12-31 | 2011-12-23 | Method of generating induced pluripotent stem cells and differentiated cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201300780A1 true EA201300780A1 (ru) | 2013-11-29 |
EA028902B1 EA028902B1 (ru) | 2018-01-31 |
Family
ID=45464553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201300780A EA028902B1 (ru) | 2010-12-31 | 2011-12-23 | Способ получения индуцированных плюрипотентных стволовых клеток и дифференцированных клеток |
Country Status (10)
Country | Link |
---|---|
US (1) | US9926532B2 (ru) |
EP (1) | EP2658965B1 (ru) |
JP (2) | JP2014501114A (ru) |
BR (1) | BR112013016592B1 (ru) |
CA (1) | CA2823265C (ru) |
DK (1) | DK2658965T3 (ru) |
EA (1) | EA028902B1 (ru) |
ES (1) | ES2575605T3 (ru) |
PT (1) | PT2658965E (ru) |
WO (1) | WO2012089669A1 (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
JP2016507231A (ja) * | 2013-02-05 | 2016-03-10 | グアンジョウ インスティテュート オブ バイオメディスン アンド ヘルス、チャイニーズ アカデミー オブ サイエンスィズGuangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences | 幹細胞を使用する歯様構造物の調製 |
US11066649B2 (en) * | 2014-03-19 | 2021-07-20 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Method for inducing human cholangiocyte differentiation |
EP3712254A1 (en) | 2014-05-28 | 2020-09-23 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
US11584916B2 (en) | 2014-10-17 | 2023-02-21 | Children's Hospital Medical Center | Method of making in vivo human small intestine organoids from pluripotent stem cells |
CN107429225B (zh) * | 2014-12-22 | 2021-11-02 | 南澳大学 | 使用小分子从尿衍生细胞诱导β细胞的方法 |
CA2995582A1 (en) | 2015-08-19 | 2017-02-23 | Children's Research Institute, Children's National Medical Center | Compositions and methods for treating graft versus host disease |
EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
SG10202105768WA (en) | 2016-12-05 | 2021-06-29 | Childrens Hospital Med Ct | Colonic organoids and methods of making and using same |
KR102150489B1 (ko) * | 2019-04-09 | 2020-09-01 | 고려대학교 산학협력단 | 소변세포로부터 신장전구세포로의 직접 역분화를 유도하는 방법 및 이의 방법으로 역분화된 신장전구세포를 포함하는 신장세포 손상 질환 예방 또는 치료용 약학 조성물 |
CN112143706A (zh) * | 2020-09-27 | 2020-12-29 | 中国科学院广州生物医药与健康研究院 | 一种将尿液细胞重编程为诱导性多能干细胞的方法 |
CN113122505A (zh) * | 2021-04-13 | 2021-07-16 | 四川大学华西医院 | 一种通过逆病毒获取尿源诱导多能干细胞的方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW438973B (en) * | 1995-12-19 | 2001-06-07 | Sysmex Corp | Apparatus and method for analyzing solid components in urine |
JP3589113B2 (ja) * | 1998-09-24 | 2004-11-17 | 田辺製薬株式会社 | 腎疾患治療薬およびそのスクリーニング方法 |
US10398804B2 (en) * | 2007-05-21 | 2019-09-03 | Wake Forest University Health Sciences | Progenitor cells from urine and methods for using the same |
EP3078738B1 (en) | 2007-08-31 | 2020-05-20 | Whitehead Institute for Biomedical Research | Wnt pathway stimulation in reprogramming somatic cells |
WO2009157201A1 (en) | 2008-06-26 | 2009-12-30 | Osaka University | Method and kit for preparing ips cells |
JP5340265B2 (ja) * | 2008-06-27 | 2013-11-13 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
US20120189595A1 (en) * | 2008-09-25 | 2012-07-26 | Salk Institute For Biological Studies | Induced pluripotent stem cells and methods of use |
WO2010065239A1 (en) * | 2008-12-05 | 2010-06-10 | Wake Forest University Health Sciences | Stem cells from urine and methods for using the same |
WO2010084275A1 (fr) * | 2009-01-26 | 2010-07-29 | Fred Zacouto | Procédé simplifié de reprogrammation génétique et épigénétique partielle de cellules. |
JP2010207162A (ja) * | 2009-03-11 | 2010-09-24 | Japan Health Science Foundation | Bacクローンを用いる尿路上皮癌の発生リスク評価方法及び予後予測方法 |
-
2011
- 2011-12-23 PT PT118058585T patent/PT2658965E/pt unknown
- 2011-12-23 DK DK11805858.5T patent/DK2658965T3/da active
- 2011-12-23 WO PCT/EP2011/073962 patent/WO2012089669A1/en active Application Filing
- 2011-12-23 ES ES11805858.5T patent/ES2575605T3/es active Active
- 2011-12-23 JP JP2013546688A patent/JP2014501114A/ja active Pending
- 2011-12-23 BR BR112013016592-8A patent/BR112013016592B1/pt active IP Right Grant
- 2011-12-23 EP EP11805858.5A patent/EP2658965B1/en active Active
- 2011-12-23 EA EA201300780A patent/EA028902B1/ru not_active IP Right Cessation
- 2011-12-23 US US13/997,976 patent/US9926532B2/en active Active
- 2011-12-23 CA CA2823265A patent/CA2823265C/en active Active
-
2017
- 2017-04-24 JP JP2017085186A patent/JP2017169574A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EA028902B1 (ru) | 2018-01-31 |
JP2014501114A (ja) | 2014-01-20 |
ES2575605T3 (es) | 2016-06-29 |
PT2658965E (pt) | 2016-06-06 |
US20130323782A1 (en) | 2013-12-05 |
US9926532B2 (en) | 2018-03-27 |
CA2823265C (en) | 2019-05-21 |
WO2012089669A1 (en) | 2012-07-05 |
EP2658965B1 (en) | 2016-03-02 |
CA2823265A1 (en) | 2012-07-05 |
EP2658965A1 (en) | 2013-11-06 |
BR112013016592B1 (pt) | 2022-03-15 |
JP2017169574A (ja) | 2017-09-28 |
BR112013016592A2 (pt) | 2021-03-30 |
DK2658965T3 (da) | 2016-06-13 |
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Legal Events
Date | Code | Title | Description |
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MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |