EA201171449A1 - Обратная генетика с использованием неэндогенных промоторов pol 1 - Google Patents

Обратная генетика с использованием неэндогенных промоторов pol 1

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Publication number
EA201171449A1
EA201171449A1 EA201171449A EA201171449A EA201171449A1 EA 201171449 A1 EA201171449 A1 EA 201171449A1 EA 201171449 A EA201171449 A EA 201171449A EA 201171449 A EA201171449 A EA 201171449A EA 201171449 A1 EA201171449 A1 EA 201171449A1
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EA
Eurasian Patent Office
Prior art keywords
uneendogenous
pol
promoters
reverse genetics
host cells
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EA201171449A
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English (en)
Other versions
EA021009B1 (ru
Inventor
Филип Дормитцер
Майкл Франти
Пирада Суфафифат
Питер Мейсон
Бьерн Кайнер
Стефания Кротта
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Новартис Аг
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Application filed by Новартис Аг filed Critical Новартис Аг
Publication of EA201171449A1 publication Critical patent/EA201171449A1/ru
Publication of EA021009B1 publication Critical patent/EA021009B1/ru

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    • A—HUMAN NECESSITIES
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    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
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  • Health & Medical Sciences (AREA)
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Abstract

Экспрессия трансгена управляется в клетках-хозяевах с помощью промотора ро1 I, который не является эндогенным для организма из того же таксономического подразделения, из которого происходят клетки-хозяева
EA201171449A 2009-05-21 2010-05-21 ОБРАТНАЯ ГЕНЕТИКА С ИСПОЛЬЗОВАНИЕМ НЕЭНДОГЕННЫХ ПРОМОТОРОВ pol I EA021009B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21691909P 2009-05-21 2009-05-21
PCT/IB2010/001332 WO2010133964A1 (en) 2009-05-21 2010-05-21 Reverse genetics using non-endogenous pol i promoters

Publications (2)

Publication Number Publication Date
EA201171449A1 true EA201171449A1 (ru) 2012-05-30
EA021009B1 EA021009B1 (ru) 2015-03-31

Family

ID=42338045

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201171449A EA021009B1 (ru) 2009-05-21 2010-05-21 ОБРАТНАЯ ГЕНЕТИКА С ИСПОЛЬЗОВАНИЕМ НЕЭНДОГЕННЫХ ПРОМОТОРОВ pol I

Country Status (19)

Country Link
US (3) US9072702B2 (ru)
EP (2) EP2401384B1 (ru)
JP (2) JP5836266B2 (ru)
KR (1) KR101800245B1 (ru)
CN (1) CN102597246B (ru)
AU (1) AU2010250832B2 (ru)
BR (1) BRPI1011171A2 (ru)
CA (1) CA2762802A1 (ru)
DK (1) DK2401384T3 (ru)
EA (1) EA021009B1 (ru)
ES (1) ES2394797T3 (ru)
HK (1) HK1165827A1 (ru)
HR (1) HRP20121048T1 (ru)
NZ (1) NZ596432A (ru)
PL (1) PL2401384T3 (ru)
PT (1) PT2401384E (ru)
SI (1) SI2401384T1 (ru)
SM (1) SMT201300034B (ru)
WO (1) WO2010133964A1 (ru)

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KR101323582B1 (ko) * 2011-03-17 2013-10-30 충북대학교 산학협력단 Ｖｅｒｏ 세포 유래의 ｐｏｌⅠ 프로모터 및 이를 포함하는 재조합 벡터
AU2013354219A1 (en) 2012-12-03 2015-07-02 Novartis Ag Reassortant influenza a viren
AU2014229255B2 (en) 2013-03-13 2018-12-13 Novartis Ag Influenza B virus reassortment
CN105722976A (zh) 2013-06-06 2016-06-29 诺华股份有限公司 流感病毒重配
WO2016148195A1 (ja) * 2015-03-17 2016-09-22 一般財団法人阪大微生物病研究会 インフルエンザウイルス作出用細胞
CN109312362B (zh) 2016-06-20 2022-06-28 扬森疫苗与预防公司 有效和平衡的双向启动子
WO2021099419A1 (en) 2019-11-18 2021-05-27 Seqirus UK Limited Method for producing reassortant influenza viruses
BR102020010208A2 (pt) 2020-05-21 2022-04-12 Fundação Oswaldo Cruz Construção de ácido nucleico, virus influenza recombinante, método para preparar um virus influenza recombinante, composição, e, uso.

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Publication number Publication date
EA021009B1 (ru) 2015-03-31
HRP20121048T1 (hr) 2013-02-28
US20120189656A1 (en) 2012-07-26
PT2401384E (pt) 2012-12-19
EP2401384B1 (en) 2012-10-03
US20190284575A1 (en) 2019-09-19
WO2010133964A1 (en) 2010-11-25
US20160024525A1 (en) 2016-01-28
HK1165827A1 (en) 2012-10-12
NZ596432A (en) 2013-05-31
SI2401384T1 (sl) 2013-01-31
US9072702B2 (en) 2015-07-07
SMT201300034B (it) 2013-05-06
EP2401384A1 (en) 2012-01-04
JP2015204843A (ja) 2015-11-19
CN102597246B (zh) 2014-02-26
KR20120028328A (ko) 2012-03-22
ES2394797T3 (es) 2013-02-05
BRPI1011171A2 (pt) 2015-08-25
AU2010250832A1 (en) 2011-12-08
JP5836266B2 (ja) 2015-12-24
KR101800245B1 (ko) 2017-11-22
EP2573184A1 (en) 2013-03-27
AU2010250832B2 (en) 2013-10-03
CN102597246A (zh) 2012-07-18
JP2012527228A (ja) 2012-11-08
DK2401384T3 (da) 2013-01-14
PL2401384T3 (pl) 2013-03-29
CA2762802A1 (en) 2010-11-25

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